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Predicting dupilumab effectiveness with Type-2 biomarkers: A real-world study of severe asthma
Published 2025-01-01“…Background: The therapeutic effectiveness of dupilumab for severe asthma in real-world settings is yet to be prospectively investigated across multiple institutions, and uncertainties persist regarding predictive factors for its effectiveness. …”
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Assessing Groundwater Connection/Disconnection to Waterholes Along the Balonne River and in the Barwon–Darling River System in Queensland and New South Wales, Australia, for Waterh...
Published 2025-01-01“…To assess the persistence of waterholes the groundwater contribution to the water balance needs to be addressed. …”
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World Café approach: exploring the future vision of oral anticoagulants for patients with atrial fibrillation (AF) in Ireland
Published 2020-09-01“…Objectives To explore and reflect on the current anticoagulation therapy offered to patients with atrial fibrillation (AF), potential challenges and the future vision for oral anticoagulants for patients with AF and healthcare professionals in Ireland.Design A multistakeholder focus group using a World Café approach.Participants Nine participants from academic, clinical and health backgrounds attended the focus group together with a facilitator.Results Enhanced patient empowerment; more effective use of technology and developing system-based medical care pathways would provide improved supports for AF management. …”
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Real-world assessment of effectiveness and safety of filgotinib in 286 patients with ulcerative colitis in 9 UK centres
Published 2025-01-01“…Conclusions: In a large real-world cohort of patients with UC, filgotinib appears to be effective and welltolerated.…”
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Comparison of Healthcare Encounters and Drug Persistence in Patients With Pulmonary Arterial Hypertension Receiving Oral Selexipag, Inhaled Iloprost, or Parenteral Treprostinil: A...
Published 2022-06-01“…**Conclusions:** In real-world use, selexipag appears to be associated with lower rates of hospitalization and outpatient visits than inhaled iloprost or parenteral treprostinil. …”
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Retrospective database analysis on the demographics and resource utilization of patients with Parkinson’s disease in Quebec, Canada
Published 2025-01-01“…Despite its recognized significance, there remains a paucity of recent studies reporting treatment utilization and the economic impact of PD in a real-world setting, especially in Canada. This study aimed to analyze real-world treatment patterns and health care resource utilization (HCRU) of patients with PD in Quebec, Canada. …”
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Persistent cross-species transmission systems dominate Shiga toxin-producing Escherichia coli O157:H7 epidemiology in a high incidence region: A genomic epidemiology study
Published 2025-01-01“…Several areas of the world suffer a notably high incidence of Shiga toxin-producing Escherichia coli. …”
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Real-world clinical outcome of unresectable locally advanced & de-novo metastatic pancreatic ductal adenocarcinoma: a multicentre retrospective study
Published 2025-01-01“…This study aimed to evaluate the real-world clinical characteristics, treatment patterns, and outcomes of patients with locally advanced unresectable and de-novo metastatic PDAC in Saudi Arabia, providing regional data to compare with international benchmarks. …”
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Tumour necrosis factor inhibitors in Ulcerative colitis: real-world data on Therapeutic drug monitoring and evaluation of current treatment targets (STRIDE II)
Published 2025-12-01“…Among 102 treatment persistent patients, 54% were in combined remission after twelve months. …”
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Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation in relation to the Patients’ Age: Results from a Large Real-World Multicenter Observational Project
Published 2021-01-01“…Background. The real-world efficacy and safety of atrial fibrillation (AF) ablation in particularly young and elderly patients are still under debate. …”
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Real-World Clinical Outcomes and Treatment Patterns Among Black and Non-Black Patients With Prostate Cancer Initiated on Apalutamide in a Urology Setting
Published 2024-08-01“…**Conclusions:** In this real-world study of patients with mCSPC or nmCRPC initiated on apalutamide, treatment persistence was high and apalutamide demonstrated robust real-world effectiveness with respect to progression to castration resistance, CRFS, and MFS, overall and among Black and non-Black patients.…”
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Risdiplam utilization, adherence, and associated health care costs for patients with spinal muscular atrophy: a United States retrospective claims database analysis
Published 2024-12-01“…This retrospective claims database analysis assessed real-world treatment adherence and persistence, and all-cause health care costs by adherence status, for patients with SMA receiving risdiplam. …”
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Evaluating the Benefit of Home Support Provider Services for Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea: Protocol for an Ambispective International R...
Published 2025-01-01“…Hierarchical models, adjusted for preidentified confounding factors, will be used to assess the net effect of home support provider services on PAP adherence and persistence while minimizing real-world study biases and considering the influence of country-level contextual factors. …”
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