Adverse Maternal Outcomes and Associated Factors Among Mothers of Advanced Age delivering at a Tertiary Hospital, Southwestern Uganda: A Cross-Sectional Study. by Masembe, Sezalio, Migisha, Richard, Turyasingura, Godwin, Aheisibwe, Hillary, Nzabandora, Emmanuel, Lule, John C.

“…We conducted a cross-sectional study at the Maternity Ward of KRRH from April to September 2023. We consecutively enrolled pregnant women aged≥35 years during their immediate post-delivery period and before discharge. …”
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Factors Associated with Healthcare-Seeking Behavior among Health Profession Students in Selected Universities in Southwestern Uganda. by Wamaani, Hannington Gamukama, Olum, Ronald, Ajuna, Noble, Atwijukire, Humphrey, Kabami, Jane, Asiimwe, John Baptist

“…Results: A total of 400 HPS were enrolled, 60.3% were males, and the mean age of the participants was 23.06 (SD =2.74) years. …”
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Developing a clinical prediction model to modify empirical antibiotics for non-typhoidal Salmonella bloodstream infection in children under-five in the Democratic Republic of Congo by Bieke Tack, Daniel Vita, Jules Mbuyamba, Emmanuel Ntangu, Hornela Vuvu, Immaculée Kahindo, Japhet Ngina, Aimée Luyindula, Naomie Nama, Tito Mputu, Justin Im, Hyonjin Jeon, Florian Marks, Jaan Toelen, Octavie Lunguya, Jan Jacobs, Ben Van Calster

“…Results NTS bloodstream infection was diagnosed in 12.7% (295/2327) of enrolled children. The area under the curve was 0.79 (95%CI: 0.76–0.82) for the prediction model, and 0.78 (0.85–0.80) for the scoring system. …”
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Comparative Analysis of Automated and Handheld Breast Ultrasound Findings for Small (≤1 cm) Breast Cancers Based on BI-RADS Category by Han Song Mun, Eun Young Ko, Boo-Kyung Han, Eun Sook Ko, Ji Soo Choi, Haejung Kim, Myoung Kyoung Kim, Jieun Kim

“…Patients with tumors measuring ≤1 cm on either modality were enrolled. Two breast radiologists retrospectively evaluated multiple imaging features, including shape, orientation, margin, echo pattern, and posterior characteristics and assigned BI-RADS categories. …”
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Effect of prenatal multiple micronutrient supplementation on birth weight in Ethiopia: protocol for a pragmatic cluster-randomised trial by Joanna Schellenberg, Charles Opondo, Tanya Marchant, Lars Åke Persson, Masresha Tessema, Atkure Defar, Alemneh Kabeta Daba, Girum Taye, Senait Alemayehu, Elias Asfaw, Anene Tesfa, Bedasa Tessema, Kalkidan Zenebe

“…During the study period, the birth weights of all eligible babies born in enrolled health facilities in these 42 districts are continuously recorded alongside data on maternal receipt and use of either multiple micronutrient or iron-folic acid supplementation. …”
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Sofosbuvir-Based Therapies for Patients with Hepatitis C Virus Infection: Real-World Experience in China by Chengguang Hu, Guosheng Yuan, Junwei Liu, Huaping Huang, Yanyu Ren, Yinping Li, Xuefu Chen, Wei Li, Tao Wu, Hong Deng, Yanzhong Peng, Yong-Yuan Zhang, Yuanping Zhou

“…A total of 226 patients receiving SOF plus daclatasvir (DCV), ledipasvir (LDV), or velpatasvir (VEL) were enrolled from December 2014 to June 2017. The primary observation point was the percentage of patients with a sustained virologic response (SVR) at posttreatment week 12 (SVR12), and all adverse events were monitored during treatment and follow-up period. …”
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Longitudinal associations between air pollution and incident dementia as mediated by MRI-measured brain volumes in the UK Biobank by Rhiannon Thompson, Xinning Tong, Xueyi Shen, Jinjun Ran, Shengzhi Sun, Xiaoxin Iris Yao, Chen Shen

“…Methods: UK Biobank is a large long-term study of 500,000 adults enrolled from 2006 to 2010 age 40–69 years. ICD-10 classified reports of dementia cases up to 2022 (Alzheimer’s disease, vascular dementia, dementia in other classified diseases, and unspecified dementia) were identified from health record linkage. …”
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Low transthyretin is associated with the poor prognosis of colorectal cancer by Zhe Zhang, Zhe Zhang, Zhe Zhang, Chenhao Hu, Chenhao Hu, Chenhao Hu, Feiyu Shi, Feiyu Shi, Feiyu Shi, Lei Zhang, Lei Zhang, Lei Zhang, Ya Wang, Ya Wang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Xiaojiang Zhang, Xiaojiang Zhang, Xiaojiang Zhang, Junjun She, Junjun She, Junjun She

“…Furthermore, an additional cohort of 377 CRC patients enrolled between January 2014 and December 2015 was included as an external validation.ResultsBased on the optimal cut-off value of 121.3 mg/L, we divided the patients into the TTR-lower group (<121.3 mg/L) and the TTR-higher group (≥121.3 mg/L). …”
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Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders by Jeffrey A Meyerhardt, Sunil Kumar, Jessica A Zerillo, Aparna Parikh, James M Cleary, Scott Rodig, Benjamin Schlechter, Kimmie Ng, Stephanie K Dougan, Nora Horick, Glenn J Hanna, Andrew L Coveler, Anuj K Patel, Nadine J McCleary, Douglas A Rubinson, Jeffrey W Clark, Kent Mouw, Kathleen Pfaff, Thomas A Abrams, Matthew B Yurgelun, Eliezer M Van Allen, S Jennifer Wang, Leah H Biller, Harshabad Singh, Emma L Welsh, Brandon M Huffman, Lestat R Ali, Megan T Hoffman, Katherine A Metayer, Shayla Murray, Alexandra Bird, Jennifer A Chan, Wolfram Goessling, Jeffrey S Wisch, Brendan Reardon, Robert J Mayer, Catherine Del Vecchio Fitz, Charlotte Kuperwasser

“…Background Recent trials suggest that programmed cell death 1 (PD-1)-directed immunotherapy may be beneficial for some patients with anal squamous cell carcinoma and biomarkers predictive of response are greatly needed.Methods This multicenter phase II clinical trial (NCT02919969) enrolled patients with metastatic or locally advanced incurable anal squamous cell carcinoma (n=32). …”
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Lymphocyte-C-reactive protein ratio upon admission to predict disease progression and ICU admission in adult patients with diabetic ketoacidosis by Yi-Jia Hu, Shu-Xiao Qiu, Jian-Nan Zhang, Qi-Qi Lai, Yi-Lu Lin, Lin-Qiong Liu, Di Wu, Hui-Ying Liu, Huan Meng, Jia-Xi Xu, Jia-Ning Zhang, Bo-Wen Liu, Yan Gao, Kai Kang, Yang Gao

“…A total of 271 adult DKA patients were enrolled and categorized into three groups: mild group (n = 42), moderate group (n = 64), and severe group (n = 165). …”
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Safety and Efficacy of Subcutaneous Rituximab in Previously Untreated Patients with CD20+ Diffuse Large B-Cell Lymphoma or Follicular Lymphoma: Results from an Italian Phase IIIb S... by Mario Petrini, Gianluca Gaidano, Andrea Mengarelli, Ugo Consoli, Armando Santoro, Anna Maria Liberati, Marco Ladetto, Vincenzo Fraticelli, Attilio Guarini, Donato Mannina, Paola Ferrando, Paolo Corradini, Pellegrino Musto, Caterina Stelitano, Dario Marino, Andrea Camera, Marco Murineddu, Roberta Battistini, Giuseppe Caparrotti, Mauro Turrini, Luca Arcaini, Simone Santini, Manuela Cerqueti, Andres J. M. Ferreri, Nicola Cantore, Alessandro Inzoli, Giovanni Cardinale, Benedetto Ronci, Giorgio La Nasa, Stefano Massimi, Gianfranco Gaglione, Valentina Barbiero, Maurizio Martelli

“…Overall, 159 patients (73 DLBCL, 86 FL) were enrolled: 103 (54 DLBCL, 49 FL) completed induction and 42 patients with FL completed 12 maintenance cycles. …”
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Associations Between Patient-Reported Nutritional Status, Toxicity, and Survival in Limited-Stage SCLC by Evgenia Taranova, Marianne Aanerud, MD, PhD, Tarje O. Halvorsen, MD, PhD, Kristin T. Killingberg, MD, PhD, Marit Slaaen, MD, PhD, Bjørn H. Grønberg, MD, PhD

“…Median PG-SGA SF score was 3.0; 52.2% had low, 29.2% intermediate, and 18.6% had high malnutrition risk; and 22.1% had 5% or more weight loss three months before enrolment. There were no significant differences in grade 3 to 4 toxicity (low: 88.1%, intermediate: 90.9%, high: 85.7%; p = 0.86), median progression-free survival (low: 15.8 months, intermediate: 11.8 months, high: 47.0 months; p = 0.25) or median OS (low: 35.5 months, intermediate: 26.8 months, high: 47.0 months; p = 0.24) across malnutrition categories. …”
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Individualized diagnosis of Parkinson’s disease based on multivariate magnetic resonance imaging radiomics and clinical indexes by Qianqian Ye, Chenhui Lin, Fangyi Xiao, Tao Jiang, Jialong Hou, Yi Zheng, Jiaxue Xu, Jiani Huang, Keke Chen, Jinlai Cai, Jingjing Qian, Weiwei Quan, Yanyan Chen

“…ObjectiveTo explore MRI-based radiomics models, integrating clinical characteristics, for differential diagnosis of Parkinson’s disease (PD) to evaluate their diagnostic performance.MethodsA total of 256 participants [153 PD, 103 healthy controls (HCs)] from the First Affiliated Hospital of Wenzhou Medical Hospital, were enrolled as the training set, and 120 subjects (74 PD, 46 HCs) from the PPMI dataset served as the test set. …”
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Percutaneous Coronary Intervention Complexity and Risk of Adverse Events in relation to High Bleeding Risk among Patients Receiving Drug-Eluting Stents: Insights from a Large Singl... by Hao-Yu Wang, Yang Wang, Dong Yin, Run-Lin Gao, Yue-Jin Yang, Bo Xu, Ke-Fei Dou

“…Between January 2013 and December 2013, 10,167 consecutive patients undergoing PCI were prospectively enrolled in Fuwai PCI Registry. Complex PCI was defined when having at least one of the following characteristics: 3 vessels treated, ≥3 stents implanted, ≥3 lesions treated, bifurcation with 2 stents implanted, total stent length >60 mm, treatment of chronic total occlusion, unprotected left main PCI, in-stent restenosis target lesion, and severely calcified lesion. …”
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Multimodal data-based longitudinal prognostic model for predicting atrial fibrillation recurrence after catheter ablation in patients with patent foramen ovale and paroxysmal atria... by Shoupeng Duan, Xujun Li, Jun Wang, Yuhong Wang, Tianyou Xu, Fuding Guo, Yijun Wang, Lingpeng Song, Zeyan Li, Xiaomeng Yang, Xiaoyu Shi, Hengyang Liu, Liping Zhou, Yueyi Wang, Hong Jiang, Lilei Yu

“…Methods Patients with PFO and PAF who underwent catheter ablation at the Renmin Hospital of Wuhan University from January 2018 to June 2020 were consecutively enrolled. The identification of potential risk factors was conducted using the regression method known as least absolute shrinkage and selection operator. …”
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Impact of family socio-economic status on the prognosis of heart transplantation in children by Shun Liu, Han Mo, Yiqi Zhao, Xiao Chen, Weiteng Wang, Yijing Li, Ningning Zhang, Mengni Bao, Zeyu Cui, Qian Zhao, Jun Yan, Xiumeng Hua, Jiangping Song

“…Results 64 children (median age at operation 14 years, IQR 13–15) were enrolled and one case died in hospital due to primary graft dysfunction, 63 (98.4%) children had a median follow-up of 60 months (IQR 5.9-113.9). …”
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Hyperglycemia and Correlated High Levels of Inflammation Have a Positive Relationship with the Severity of Coronavirus Disease 2019 by Wen Zhang, Chuanwei Li, Yu Xu, Binfeng He, Mingdong Hu, Guoqiang Cao, Li Li, Shuang Wu, Xia Wang, Chun Zhang, Jianping Zhao, Jungang Xie, Zihui Xu, Qi Li, Guansong Wang

“…Four hundred and sixty-one patients were enrolled in our study, and 71.58% of patients with diabetes and 13.03% of patients without diabetes had hyperglycemia. …”
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Predicting survival rates: the power of prognostic nomograms in distal cholangiocarcinoma by Jiangfeng Hu, Yuping Shi, Lihua Jin, Suhong Yi, Jinsuo Chen, Dadong Wan, Weixin Ye, Jingnan Chen, Yajing Zhang, Yang Jiang, Bensong Duan, Yuwei Dong

“…These patients were randomly assigned to either the training or validation group in a ratio of 6:4. 228 patients were enrolled from 9 hospitals in China as the external validation cohort. …”
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A multicenter retrospective study of early cardiac toxicity in operable breast cancer patients receiving concurrent dual or mono anti-HER2 therapy with postoperative radiation ther... by Jing Yang, Meng-Yun Zhou, Bo Yu, Qing Lin, Yuan Yao, Hua-Ling Wu, Qi-Wei Zhu, Ming Ye, Hua-Ying Xie, Jian-Wei Wu, Gang Cai, Rong Cai, Wei-Xiang Qi, Jia-Yi Chen, Lu Cao

“…Results: In total, 681 patients were enrolled in the analysis, of whom 567 were treated with trastuzumab-alone and 124 patients received dual anti-HER2 therapy. …”
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Association between estimated glucose disposal rate and cardiovascular diseases in patients with diabetes or prediabetes: a cross-sectional study by Jinhao Liao, Linjie Wang, Lian Duan, Fengying Gong, Huijuan Zhu, Hui Pan, Hongbo Yang

“…Methods 10,690 respondents with diabetes and prediabetes from the NHANES 1999–2016 were enrolled in the study. Three machine learning methods (SVM-RFE, XGBoost, and Boruta algorithms) were employed to select the most critical variables. …”
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