Comparing Antibody Responses to Homologous vs. Heterologous COVID-19 Vaccination: A Cross-Sectional Analysis in an Urban Bangladeshi Population by Kazi Istiaque Sanin, Mansura Khanam, Azizur Rahman Sharaque, Mahbub Elahi, Bharati Rani Roy, Md. Khaledul Hasan, Goutam Kumar Dutta, Abir Dutta, Md. Nazmul Islam, Md. Safiqul Islam, Md. Nasir Ahmed Khan, Mustufa Mahmud, Nuzhat Nadia, Fablina Noushin, Anjan Kumar Roy, Protim Sarker, Fahmida Tofail

“…Methods: This cross-sectional study enrolled 723 adults in urban Dhaka who had received COVID-19 booster doses within the last six months. …”
Get full text

Surgical Treatment of Idiopathic Macular Hole Using Different Types of Tamponades and Different Postoperative Positioning Regimens by M. Veith, J. Vránová, J. Němčanský, J. Studnička, M. Penčák, Z. Straňák, P. Mojžíš, P. Studený, D. P. Piñero

“…Prospective randomized clinical trial enrolling 104 eyes of 100 patients (age, 57–87 years) undergoing MH surgery. …”
Get full text

Vδ2 T-cells response in people with Mpox infection: a three-month longitudinal assessment by Eleonora Cimini, Eleonora Tartaglia, Francesco Messina, Andrea Coppola, Valentina Mazzotta, Massimo Tempestilli, Giulia Matusali, Stefania Notari, Annalisa Mondi, Gianluca Prota, Alessandra Oliva, Carla Fontana, Enrico Girardi, Fabrizio Maggi, Andrea Antinori

“…Fourteen MSM subjects (5 PWH, 35.7%) were enrolled in a longitudinal study from May to July 2022. …”
Get full text

Association of β-Blocker Therapy at Discharge with Clinical Outcomes after Acute Coronary Syndrome in Patients without Heart Failure by Yan Chen, Xiao-fang Tang, Run-lin Gao, Yue-jin Yang, Bo Xu, Jin-qing Yuan

“…A total of 10,724 consecutive patients who underwent PCI throughout 2013 were prospectively enrolled in the study. Among these, we analyzed 5,631 ACS patients who were discharged with LVEF≥40%. …”
Get full text

The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled mult... by Toby M Maher, A John Simpson, Anthony Cahn, David Thickett, Luke Vale, Allan B Clark, Nazia Chaudhuri, Ian Forrest, Lisa G Spencer, Christopher Ward, Stephen Jones, Ganesh Raghu, Andrew M Wilson, Helen Parfrey, Megan Jones, Matthew Hammond, Jaclyn Ann Smith, Shajahan Wahed

“…We aim to undertake an adequately powered double-blind placebo-controlled randomised multicentre clinical trial to assess the change in forced vital capacity (FVC), cough and other important patient-reported outcomes, following 12-month therapy with PPIs in people with IPF.Methods and analysis A total of 298 patients with IPF diagnosed by a multidisciplinary team according to international guidelines who are not receiving PPIs will be enrolled. Patients are randomised equally to receive two capsules of lansoprazole or two placebo capsules, two times per day for 12 months. …”
Get full text

High HDL-C and high LDL-C are risk factors of pterygium in a population-based cross-sectional study in Southern China: the Dongguan Eye Study by Liang Zhang, Min Zhang, Ying Cui, Lixin Zhang, Guanrong Zhang, Qingyang Liu, Haike Guo, Qianli Meng, Siwen Zang, Chun-Han Lo, Yanlei Chen, Jin Zeng

“…Objectives To investigate the relationship between serum lipids and pterygium in a large-scale rural population aged 40 years or older from Southern China.Study design The Dongguan Eye Study was a cross-sectional population-based study from September 2011 to February 2012.Setting The area was set in the rural area of Dongguan, Southern China.Participants Adult rural population aged 40 or older.Methods Participants underwent physical, haematological and ophthalmic examinations.Primary and secondary outcome measures The frequency and risk factors of pterygium.Results A total of 11 357 participants were eligible for inclusion and 8952 (78.8%) participants were enrolled for the systemic and ophthalmic examinations. …”
Get full text

Pediatric bacterial meningitis in southern China: analysis of 838 cases by Lianfeng Chen, Wen-Lin Wu, Yuanyuan Gao, Xiaojing Li, Sida Yang, Huici Liang, Kelu Zheng, Yani Zhang, Haixia Zhu, Yang Tian, Bingwei Peng, Haisheng Lin, Xiuying Wang, Shuyao Ning, Yinyan Gan, Chi Hou, Yinting Liao, Huiling Sheng, Wen-Xiong Chen, Wen-Xiong Chen

“…ObjectiveThis work aims to study the clinical features and risk factors of children with bacterial meningitis (BM) in southern China.MethodsClinical data of children with BM between 2012 and 2018 from one national center were analyzed retrospectively.ResultsA total of 838 patients (male/female = 1.8:1) were enrolled, with 90.6% under 1 year old. Common symptoms included fever, seizure, lethargy, vomiting, anorexia, poor feeding, and irritability. …”
Get full text

Cross-sectional design and protocol for Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) by Gerald McGwin, Linda M Zangwill, Nicholas Evans, Shannon McWeeney, Cecilia S Lee, Bhavesh Patel, Jeffrey C Edberg, Cynthia Owsley, Aaron Lee, Cecilia Lee, Sally L Baxter, Michael Snyder, Samantha Hurst, Nicole Ehrhardt, Christopher Chute, Dawn S Matthies, Julia P Owen, Amir Bahmani, Sally Baxter, Edward Boyko, Aaron Cohen, Jorge Contreras, Garrison Cottrell, Virginia de Sa, Jeffrey Edberg, Irl Hirsch, Michelle Hribar, T.Y. Alvin Liu, Bonnie Maldenado, Sara Singer, Bradley Voytek, Joseph Yracheta, Linda Zangwill

“…The fundamental rationale for promoting health resilience in T2DM stems from its high prevalence of 10.5% of the world’s adult population and its contribution to many adverse health events.Methods AI-READI is a cross-sectional study whose target enrollment is 4000 people aged 40 and older, triple-balanced by self-reported race/ethnicity (Asian, black, Hispanic, white), T2DM (no diabetes, pre-diabetes and lifestyle-controlled diabetes, diabetes treated with oral medications or non-insulin injections and insulin-controlled diabetes) and biological sex (male, female) (Clinicaltrials.org approval number STUDY00016228). …”
Get full text

Application of Minocycline-Containing Bismuth Quadruple Therapies as First-Line Regimens in the Treatment of Helicobacter pylori by Lingyun Zhang, Yu Lan, Qi Wang, Yuexia Zhang, Xiaobei Si

“…A total of 360 patients with an untreated H. pylori infection were enrolled in this study between June 2017 and October 2018. …”
Get full text

Epi-Off versus Epi-On Corneal Collagen Cross-Linking in Keratoconus Patients: A Comparative Study through 2-Year Follow-Up by F. Cifariello, M. Minicucci, F. Di Renzo, D. Di Taranto, G. Coclite, S. Zaccaria, S. De Turris, C. Costagliola

“…Forty eyes from 32 patients with progressive keratoconus were prospectively enrolled from June 2014 to June 2015 in this nonblinded, randomized comparative study. …”
Get full text

Socio-demographic portrait of the applicant and the main motives for choosing the "Therapy and rehabilitation" speciality by S.V. Zakharov, O.B. Nekhanevych, O.O. Rusakova, O.V. Smolianova

“…To achieve this goal, a voluntary anonymous survey of 39 domestic applicants enrolled to complete the bachelor's degree program in speciality 227 "Therapy and rehabilitation" at Dnipro State Medical University was conducted. …”
Get full text

Incidence and risk factors for clinical omphalitis among neonates in Eastern Uganda using chlorhexidine gel for cord care: a community-cohort study by John Wogabaga, Kathy Burgoine, Abel Kakuru, Brendah Nambozo, Martin Chebet, Josephine Tumuhamye, Benon Wanume, Faith Oguttu, Milton W. Musaba, Agnes Napyo, Solomon Wani, Peter Olupot-Olupot, Andrew D. Weeks, Thorkild Tylleskär, David Mukunya

“…Results A total of 2052 neonates were enrolled; half of which were female (51.1%). The incidence of omphalitis was 3.0% (62/2052; 95% confidence interval (CI): 1.9%, 4.4%). …”
Get full text

Enhancing healthcare utilization and reducing preventable hospitalizations: exploring the healthcare-seeking propensity of patients with non-communicable diseases in Rural China by Yanqiu Hou, Wenyu Li, Shangai Li, Linxuan Chen, Jiayu An, Shan Lu

“…Factors such as age, education level, income, accessibility to healthcare, and enrollment in family doctor services influenced healthcare-seeking propensity for both types of symptoms. …”
Get full text

Use of cannabis during pregnancy and birth outcomes in an Aboriginal birth cohort: a cross-sectional, population-based study by Deirdre Gartland, Stephanie J Brown, Karen Glover, Fiona K Mensah, Cathy Leane, Jane Yelland, Jackie Ah Kit, Deanna Stuart-Butler, Donna Weetra, Jonathan Newbury

“…Data include: maternal cannabis use, exposure to stressful events/social health issues, infant birth weight and gestation.Participants 344 eligible women with a mean age of 25 years (range 15–43 years), enrolled in the study. Participants were representative in relation to maternal age, infant birth weight and gestation.Results 1 in 5 women (20.5%) used cannabis during pregnancy, and 52% smoked cigarettes. …”
Get full text

Effectiveness of Frequent Point-of-Care Molecular COVID-19 Surveillance in a Rural Workplace: Nonrandomized Controlled Clinical Trial Among Miners by Akshay Sood, William “Cotton” Jarrell, Xin W Shore, Nestor Sosa, Alisha Parada, Nicholas Edwardson, Alexandra V Yingling, Teah Amirkabirian, Qiuying Cheng, Ivy Hurwitz, Linda S Cook, Shuguang Leng, Orrin B Myers, Douglas J Perkins

“…MethodsIn this nonrandomized controlled clinical trial conducted from February 2021, to March 2022, 169 miners in New Mexico (intervention cohort) and 61 miners in Wyoming (control cohort) were enrolled. Investigators performed point-of-care rapid antigen testing on midnasal swabs (NSs) self-collected by intervention miners. …”
Get full text

Immune checkpoint inhibitor‐related type 1 diabetes incidence, risk, and survival association by Fumika Kamitani, Yuichi Nishioka, Miyuki Koizumi, Hiroki Nakajima, Yukako Kurematsu, Sadanori Okada, Shinichiro Kubo, Tomoya Myojin, Tatsuya Noda, Tomoaki Imamura, Yutaka Takahashi

“…Patients administered ICI between 2014 and 2022 were enrolled in the study, including 21,121 patients. The risk factors for ICI‐T1DM development and their characteristics were evaluated by logistic regression analysis. …”
Get full text

Prediction model study focusing on eHealth in the management of urinary incontinence: the Personalised Advantage Index as a decision-making aid by Huibert Burger, Henk van der Worp, Marco H Blanker, Marjolein Y Berger, Anne Martina Maria Loohuis, Nienke Wessels, Janny Dekker, Alec GGA Malmberg

“…Objective To develop a prediction model and illustrate the practical potential of personalisation of treatment decisions between app-based treatment and care as usual for urinary incontinence (UI).Design A prediction model study using data from a pragmatic, randomised controlled, non-inferiority trial.Setting Dutch primary care from 2015, with social media included from 2017. Enrolment ended on July 2018.Participants Adult women were eligible if they had ≥2 episodes of UI per week, access to mobile apps and wanted treatment. …”
Get full text

Early Changes in Tumor Perfusion from T1-Weighted Dynamic Contrast-Enhanced MRI following Neural Stem Cell-Mediated Therapy of Recurrent High-Grade Glioma Correlate with Overall Su... by Prativa Sahoo, Paul Frankel, Julie Ressler, Margarita Gutova, Alexander J. Annala, Behnam Badie, Jana Portnow, Karen S. Aboody, Massimo D’Apuzzo, Russell C. Rockne

“…A total of 12 patients were included in this retrospective study. All patients were enrolled in a first-in-human study (NCT01172964) of NSC-mediated therapy for recurrent high-grade glioma. …”
Get full text

Luteal Phase Stimulation in the Same Cycle Is an Effective Strategy to Rescue POSEIDON Poor Responders with No Embryos after the First Follicular Stimulation by Abha Majumdar, Gaurav Majumdar, Neeti Tiwari, Anu Singh, Shweta Mittal Gupta, Ruma Satwik

“…Settings and Design: This was a retrospective cohort study of 131 patients who enrolled to undergo DuoStim cycles from January 2021 to Sept. 2022, at a IVF center in a tertiary care hospital. …”
Get full text

Relationship between CCL25/CCR9 Levels in Follicular Fluid and High Ovarian Response in Patients with Polycystic Ovary Syndrome by Yongxin Hao, Qianqian Yin, Fangfang Hu, Xiaoyan Liu, Yaru Yang, Fang Sun, Xiaonan Yan

“…A total of 200 PCOS patients who received a fixed regimen of gonadotropin-releasing hormone (GnRH) antagonist were enrolled in this study. The cohort comprised 118 patients exhibiting HOR and 82 patients demonstrating a normal ovarian response (NOR). …”
Get full text