Diagnostic accuracy of calculated serum osmolarity to predict dehydration in older people: adding value to pathology laboratory reports by Lee Shepstone, John F Potter, Lee Hooper, Asmaa Abdelhamid, Amy Jennings, Paul R Hunter, W Garry John, Neil P Walsh, Adam Ali, Diane K Bunn, Susan Kerry, Gregor Lindner, Carmen A Pfortmueller, Fredrik Sjöstrand, Susan J Fairweather-Tait

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Costs of community-wide mass drug administration and school-based deworming for soil-transmitted helminths: evidence from a randomised controlled trial in Benin, India and Malawi by Judd Walson, ROBIN BAILEY, Katya Galactionova, Maitreyi Sahu, Samuel Paul Gideon, Saravanakumar Puthupalayam Kaliappan, Chloe Morozoff, Sitara Swarna Rao Ajjampur, Khumbo Kalua, Euripide Avokpaho, Moudachirou Ibikounle, Arianna Rubin Means, James Simwanza, Wongani Lungu, Parfait Houngbegnon, Adrian J F Luty, Rachel Pullan

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Safety of influenza vaccination during pregnancy: a systematic review by Brian Hutton, David Moher, Danielle B Rice, Claire Butler, Andrea C Tricco, Becky Skidmore, Candyce Hamel, Chantelle Garritty, Paul A Khan, Marco Ghassemi, Charlene Soobiah, Leila Esmaeilisaraji, Dianna M Wolfe, Deshayne Fell, Mona Hersi, Nadera Ahmadzai, Alan Michaud, Angela Sinilaite

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Prehospital scale to differentiate intracerebral hemorrhage from large-vessel occlusion patients: a prospective cohort study by A. Freixa-Cruz, G. Jimenez-Jimenez, G. Mauri-Capdevila, Y. Gallego-Sánchez, A. García-Díaz, R. Mitjana-Penella, M. Paul-Arias, C. Pereira-Priego, E. Ruiz-Fernández, S. Salvany-Montserrat, A. Sancho-Saldaña, E. San-Pedro-Murillo, E. Saureu, D. Vázquez-Justes, Francisco Purroy

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Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice by Fabiola Silva Angulo, Claudine Vanessa Joseph, Lou Delval, Lucie Deruyter, Séverine Heumel, Marie Bicharel, Patricia Brito Rodrigues, Valentin Sencio, Tom Bourguignon, Marina Gomes Machado, Marie Fourcot, Stéphane Delhaye, Sophie Salomé-Desnoulez, Philippe Valet, Serge Adnot, Isabelle Wolowczuk, Jean-Claude Sirard, Muriel Pichavant, Bart Staels, Joel T. Haas, Ruxandra Gref, Jimmy Vandel, Arnaud Machelart, Hélène Duez, Benoit Pourcet, François Trottein

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Comparative effectiveness of urine drug screening strategies alongside opioid agonist treatment in British Columbia, Canada: a population-based observational study protocol by Malcolm Maclure, M Eugenia Socías, Evan Wood, Paul Gustafson, Robert W Platt, Bohdan Nosyk, Jeong Eun Min, Micah Piske, Julie Bruneau, U Siebert, P Todd Korthuis, Paxton Bach, B Carolina Guerra-Alejos, Megan Kurz, Laura M Dale, X Joan Hu, Kyle Kampman, Tom Loughin

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Prediction of pathological complete response after neoadjuvant chemotherapy for HER2-negative breast cancer patients with routine immunohistochemical markers by Lothar Häberle, Ramona Erber, Paul Gass, Alexander Hein, Melitta Niklos, Bernhard Volz, Carolin C. Hack, Rüdiger Schulz-Wendtland, Hanna Huebner, Chloë Goossens, Matthias Christgen, Thilo Dörk, Tjoung-Won Park-Simon, Andreas Schneeweiss, Michael Untch, Valentina Nekljudova, Sibylle Loibl, Arndt Hartmann, Matthias W. Beckmann, Peter A. Fasching

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Anti-phenolic glycolipid antibodies in Mycobacterium bovis infected cattle by Zijie Zhou, Anouk van Hooij, J. Hessel M. van Dijk, Nina Musch, Louise Pierneef, Hamza Khalid, Kees Franken, Thomas Holder, Neil Watt, Anita L. Michel, Jeroen D.C. Codée, Martin Vordermeier, Paul L.A.M. Corstjens, Elisabeth M.D.L. van der Heijden, Jayne C. Hope, Annemieke Geluk

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Subcutaneous sarilumab for the treatment of hospitalized patients with moderate to severe COVID19 disease: A pragmatic, embedded randomized clinical trial. by Westyn Branch-Elliman, Ryan Ferguson, Gheorghe Doros, Patricia Woods, Sarah Leatherman, Judith Strymish, Rupak Datta, Rekha Goswami, Matthew D Jankowich, Nishant R Shah, Thomas H Taylor, Sarah T Page, Sara J Schiller, Colleen Shannon, Cynthia Hau, Maura Flynn, Erika Holmberg, Karen Visnaw, Rupali Dhond, Mary Brophy, Paul A Monach

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A Retrospective, Single-Center Assessment of Changes in Pain, Agitation, and Delirium Management Before and During the COVID-19 Pandemic by Rachel L. Winner, PharmD, BCCCP, Lydia R. Ware, PharmD, BCPS, BCCCP, Kevin M. Dube, PharmD, BCPS, BCCCP, Mary P. Kovacevic, PharmD, BCPS, BCCCP, Kenneth E. Lupi, PharmD, BCPS, BCCCP, Paul M. Szumita, PharmD, FCCM, FASHP, BCCCP, BCPS, Jeremy R. DeGrado, PharmD, BCCCP

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Association of exposure to second-hand smoke during childhood with blood DNA methylation by Marta Cosin-Tomas, Thanh Hoang, Cancan Qi, Giulietta S. Monasso, Ryan Langdon, Simon Kebede Merid, Lucinda Calas, Paula de Prado-Bert, Rebecca Richmond, Vincent VW Jaddoe, Liesbeth Duijts, John Wright, Isabella Annesi-Maesano, Regina Grazuleviciene, Marianna Karachaliou, Gerard H. Koppelman, Erik Melén, Olena Gruzieva, Martine Vrijheid, Paul Yousefi, Janine F. Felix, Stephanie J. London, Mariona Bustamante

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Impact of COVID-19 on rheumatic diseases in india: Determinants of mortality and adverse outcome: A retrospective, cross-sectional cohort study by Avinash Jain, Vineeta Shobha, S Chandrashekara, Padmanabha Shenoy, Sapan C Pandya, Prakash Chotalia, Sharath Kumar, Sourabh Malviya, Yogesh Preet Singh, Abhishek Patil, Vikas Gupta, Puja Srivastava, Vijaya Prasanna Parimi, Chanakya Kodishala, Ramya Janardana, Benzeeta Pinto, Sudhir Bhandari, Govind Rankawat, Praveen Pratap Jadhav, Damodaram Potugari, Vishnu Sharma, Alpana Parmar, Sunitha Kayidhi, Paul T Antony, Ashish Badika, Amit Sharma

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TARGET Protein: the effect of augmented administration of enteral protein to critically ill adults on clinical outcomes—statistical analysis plan for a cluster randomized, cross-se... by Sophie Zaloumis, Matthew J. Summers, Jeffrey J. Presneill, Rinaldo Bellomo, Lee-anne S. Chapple, Marianne J. Chapman, Adam M. Deane, Suzie Ferrie, Craig French, Sally Hurford, Nima Kakho, Matthew J. Maiden, Stephanie N. O’Connor, Sandra L. Peake, Emma J. Ridley, An Tran-Duy, Patricia J. Williams, Paul J. Young, Amalia Karahalios, on behalf of the TARGET Protein Investigators, the Australian, New Zealand Intensive Care Society Clinical Trials Group

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Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS... by Ramakanth Kavuluru, Xuan Wang, Paul Avillach, Florence Bourgeois, Kee Yuan Ngiam, Gabriel A Brat, Isaac Kohane, Tianxi Cai, Yuk-Lam Ho, Yuan Luo, Harrison G Zhang, Kelly Cho, Vincent Benoit, Antoine Neuraz, Chuan Hong, Sehi L'Yi, Griffin Weber, Bryce W Q Tan, Alba Gutiérrez-Sacristán, Clara-Lea Bonzel, Nathan P Palmer, Alberto Malovini, Valentina Tibollo, Meghan R Hutch, Molei Liu, Riccardo Bellazzi, Luca Chiovato, Fernando J Sanz Vidorreta, Trang T Le, William Yuan, Bertrand Moal, Michele Morris, David A Hanauer, Sarah Maidlow, Kavishwar Wagholikar, Shawn Murphy, Hossein Estiri, Adeline Makoudjou, Patric Tippmann, Jeffery Klann, Robert W Follett, Nils Gehlenborg, Gilbert S Omenn, Zongqi Xia, Arianna Dagliati, Shyam Visweswaran, Lav P Patel, Danielle L Mowery, Emily R Schriver, Malarkodi Jebathilagam Samayamuthu, Sara Lozano-Zahonero, Daniela Zöller, Amelia L M Tan, Byorn W L Tan, John H Holmes, Petra Schubert, Brett K. Beaulieu-Jones, Miguel Pedrera-Jiménez, Noelia García-Barrio, Pablo Serrano-Balazote, Andrew South

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The NANOGrav 15 Yr Data Set: Removing Pulsars One by One from the Pulsar Timing Array by Gabriella Agazie, Akash Anumarlapudi, Anne M. Archibald, Zaven Arzoumanian, Jeremy G. Baier, Paul T. Baker, Bence Bécsy, Laura Blecha, Adam Brazier, Paul R. Brook, Sarah Burke-Spolaor, J. Andrew Casey-Clyde, Maria Charisi, Shami Chatterjee, Tyler Cohen, James M. Cordes, Neil J. Cornish, Fronefield Crawford, H. Thankful Cromartie, Kathryn Crowter, Megan E. DeCesar, Paul B. Demorest, Heling Deng, Lankeswar Dey, Timothy Dolch, Elizabeth C. Ferrara, William Fiore, Emmanuel Fonseca, Gabriel E. Freedman, Emiko C. Gardiner, Nate Garver-Daniels, Peter A. Gentile, Kyle A. Gersbach, Joseph Glaser, Deborah C. Good, Lydia Guertin, Kayhan Gültekin, Jeffrey S. Hazboun, Ross J. Jennings, Aaron D. Johnson, Megan L. Jones, Andrew R. Kaiser, David L. Kaplan, Luke Zoltan Kelley, Matthew Kerr, Joey S. Key, Nima Laal, Michael T. Lam, William G. Lamb, Bjorn Larsen, T. Joseph W. Lazio, Natalia Lewandowska, Tingting Liu, Duncan R. Lorimer, Jing Luo, Ryan S. Lynch, Chung-Pei Ma, Dustin R. Madison, Alexander McEwen, James W. McKee, Maura A. McLaughlin, Natasha McMann, Bradley W. Meyers, Patrick M. Meyers, Hannah Middleton, Chiara M. F. Mingarelli, Andrea Mitridate, Christopher J. Moore, Cherry Ng, David J. Nice, Stella Koch Ocker, Ken D. Olum, Timothy T. Pennucci, Benetge B. P. Perera, Nihan S. Pol, Henri A. Radovan, Scott M. Ransom, Paul S. Ray, Joseph D. Romano, Jessie C. Runnoe, Alexander Saffer, Shashwat C. Sardesai, Ann Schmiedekamp, Carl Schmiedekamp, Kai Schmitz, Brent J. Shapiro-Albert, Xavier Siemens, Joseph Simon, Magdalena S. Siwek, Sophia V. Sosa Fiscella, Ingrid H. Stairs, Daniel R. Stinebring, Kevin Stovall, Abhimanyu Susobhanan, Joseph K. Swiggum, Stephen R. Taylor, Jacob E. Turner, Caner Unal, Michele Vallisneri, Alberto Vecchio, Sarah J. Vigeland, Haley M. Wahl, Caitlin A. Witt, David Wright, Olivia Young

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The Eczema Bathing Study: Weekly versus daily bathing for people with eczema? Protocol of an online, randomised controlled trial [version 2; peer review: 1 approved, 2 approved wit... by Paul Leighton, Wei Chern Gavin Fong, Ingrid Muller, Laura Howells, Arabella Baker, Eleanor J Mitchell, Eleanor Harrison, Leila Thuma, Yimin Jiang, Lucy Bradshaw, Alan Montgomery, Fiona Cowdel, Matthew J Ridd, Jane Ravenscroft, Reiko J Tanaka, Miriam Santer, Richard Swinden, Nicholas Hilken, Carron Layfield, Richard Dooley, Sophia Collins, Clare Upton, Tracy Owen, Firoza Davies, Devin Patel, Mars Eddis-Finbow, Hywel C Williams, Goldie Putrym, Kim S Thomas, Amanda Roberts

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Robotic Versus Laparoscopic Liver Resection: A Nationwide Propensity Score Matched Analysis by Gabriela Pilz da Cunha, MD, Jasper P. Sijberden, MD, PhD, Susan van Dieren, PhD, Paul Gobardhan, MD, PhD, Daan J. Lips, MD, PhD, Türkan Terkivatan, MD, PhD, Hendrik A. Marsman, MD, PhD, Gijs A. Patijn, MD, PhD, Wouter K. G. Leclercq, MD, PhD, Koop Bosscha, MD, PhD, J. Sven D. Mieog, MD, PhD, Peter B. van den Boezem, MD, PhD, Maarten Vermaas, MD, PhD, Niels F. M. Kok, MD, PhD, Eric J. T. Belt, MD, PhD, Marieke T. de Boer, MD, PhD, Wouter J. M. Derksen, MD, PhD, Hans Torrenga, MD, PhD, Paul M. Verheijen, MD, PhD, Steven J. Oosterling, MD, PhD, Arjen M. Rijken, MD, PhD, Marielle M. E. Coolsen, MD, PhD, Mike S. L. Liem, MD, PhD, T.C. Khé Tran, MD, PhD, Michael F. Gerhards, MD, PhD, Vincent Nieuwenhuijs, MD, PhD, Mohammad Abu Hilal, MD, PhD, Marc G. Besselink, MD, PhD, Ronald M. van Dam, MD, PhD, Jeroen Hagendoorn, MD, PhD, Rutger-Jan Swijnenburg, MD, PhD, for the Dutch Hepatobiliary Audit Group

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Investigation of the use of a sensor bracelet for the presymptomatic detection of changes in physiological parameters related to COVID-19: an interim analysis of a prospective coho... by Stefanie Aeschbacher, David Conen, Diederick E Grobbee, Raphael Twerenbold, Thomas Lung, Theo Rispens, Jakob Kjellberg, Lorenz Risch, Martin Risch, Marianna Mitratza, Harald Renz, Spiros Denaxas, Billy Franks, Diederick Grobbee, Martina Rothenbühler, Janneke Wijgert, Santiago Montes, Richard Dobson, Hans Reitsma, Christian Simon, Titia Leurink, Charisma Hehakaya, Patricia Bruijning, Kirsten Grossmann, Ornella C Weideli, Marc Kovac, Fiona Pereira, Nadia Wohlwend, Corina Risch, Dorothea Hillmann, Daniel Leibovitz, Vladimir Kovacevic, Andjela Markovic, Paul Klaver, Timo B Brakenhoff, George S Downward, Ariel Dowling, Maureen Cronin, Brianna M Goodale, Brianna Goodale, Ornella Weideli, Regien Stokman, Hans Van Dijk, Eric Houtman, Jon Bouwman, Kay Hage, Lotte Smets, Marcel van Willigen, Maui Chodura, Niki de Vink, Tessa Heikamp, Timo Brakenhoff, Wendy van Scherpenzeel, Wout Aarts, Alison Kuchta, Antonella Chiucchiuini, Steve Emby, Annemarijn Douwes, George Downward, Nathalie Vigot, Pieter Stolk, Duco Veen, Daniel Oberski, Amos Folarin, Pablo Fernandez Medina, Eskild Fredslund

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Large range sizes link fast life histories with high species richness across wet tropical tree floras by Timothy R. Baker, Stephen Adu-Bredu, Kofi Affum-Baffoe, Shin-ichiro Aiba, Perpetra Akite, Miguel Alexiades, Everton Almeida, Edmar Almeida de Oliveira, Esteban Alvarez Davila, Christian Amani, Ana Andrade, Luiz Aragao, Alejandro Araujo-Murakami, Eric Arets, Luzmila Arroyo, Peter Ashton, Suspense A. Averti Ifo, Gerardo A. C. Aymard, Michel Baisie, William Balee, Michael Balinga, Lindsay F. Banin, Olaf Banki, Christopher Baraloto, Jorcely Barroso, Jean-Francois Bastin, Hans Beeckman, Serge Begne, Natacha Nssi Bengone, Nicholas Berry, Wemo Betian, Vincent Bezard, Lilian Blanc, Pascal Boeckx, Damien Bonal, Frans Bongers, Francis Q. Brearley, Roel Brienen, Foster Brown, Musalmah Bt. Nasaradin, Benoit Burban, David F. R. P. Burslem, Plinio Camargo, Jose Luis Camargo, Wendeson Castro, Carlos Ceron, Victor Chama Moscoso, Colin Chapman, Jerome Chave, Eric Chezeaux, Murray Collins, James Comiskey, David Coomes, Fernando Cornejo Valverde, Flavia R. C. Costa, Aida Cuni-Sanchez, Lola da Costa, Douglas C. Daly, Martin Dančák, Armandu Daniels, Greta Dargie, Stuart Davies, Charles De Canniere, Thales de Haulleville, Jhon del Aguila Pasquel, Geraldine Derroire, Kyle G. Dexter, Anthony Di Fiore, Marie-Noel K. Djuikouo, Jean-Louis Doucet, Vincent Droissart, Gerald Eilu, Thaise Emillio, Julien Engel, Bocko Yannick Enock, Fidele Evouna Ondo, Corneille Ewango, Sophie Fauset, Ted R. Feldpausch, Muhammad Fitriadi, Gerardo Flores Llampazo, Ernest G. Foli, Gabriella Fredriksson, David R. Galbraith, Martin Gilpin, Emanuel Gloor, Christelle Gonmadje, Rene Guillen Villaroel, Jefferson Hall, Keith C. Hamer, Alan Hamilton, Olivier Hardy, Terese Hart, Radim Hédl, Rafael Herrera, Niro Higuchi, Claude Marcel Hladik, Eurídice Honorio Coronado, Isau Huamantupa-Chuquimaco, Walter Huaraca Huasco, Wannes Hubau, Muhammad Idhamsyah, Sascha A. Ismail, Kath Jeffery, Eliana Jimenez, Tommaso Jucker, Elizabeth Kearsley, Lip Khoon Kho, Timothy Killeen, Kanehiro Kitayama, William Laurance, Susan Laurance, Miguel Leal, Simon L. Lewis, Stanislav Lhota, Jeremy Lindsell, Gabriela Lopez-Gonzalez, Jon Lovett, Richard Lowe, William E. Magnusson, Jean-Remy Makana, Yadvinder Malhi, Beatriz Marimon, Ben Hur Marimon Junior, Andrew Marshall, Colin Maycock, Faustin Mbayu, Casimiro Mendoza, Irina Mendoza Polo, Faizah Metali, Vianet Mihindou, Abel Monteagudo-Mendoza, Sam Moore, Patrick Mucunguzi, Jacques Mukinzi, Pantaleo Munishi, Laszlo Nagy, Petrus Naisso, David Neill, Adriano Nogueira Lima, Percy Nunez Vargas, Lucas Ojo, Walter Palacios, Nadir Pallqui Camacho, Alexander Parada Gutierrez, Julie Peacock, Kelvin S.-H. Peh, Antonio Pena Cruz, Colin Pendry, Toby Pennington, Maria Cristina Penuela-Mora, Pascal Petronelli, Oliver L. Phillips, Georgia Pickavance, G. John Pipoly, Nigel Pitman, Axel Dalberg Poulsen, Ghillean T. Prance, Adriana Prieto, Richard B. Primack, Lan Qie, Simon A. Queenborough, Terry Sunderland, Carlos Quesada, Freddy Ramirez Arevalo, Hirma Ramirez-Angulo, Jan Reitsma, Maxime Réjou-Méchain, Anand Roopsind, Francesco Rovero, Ervan Rutishauser, Kamariah Abu Salim, Rafael Salomao, Ismayadi Samsoedin, Muhd Shahruney Saparudin, Juliana Schietti, Ricardo A. Segovia, Julio Serrano, Rafizah Serudia, Douglas Sheil, Natalino Silva, Javier Silva Espejo, Marcos Silveira, Murielle Simo-Droissart, James Singh, Bonaventure Sonké, Thaise Emilio Lopes De Sousa, Juliana Stropp, Rahayu Sukri, Terry Sunderland, Martin Svátek, Michael Swaine, Hermann Taedoumg, Joey Talbot, Sylvester Tan, James Taplin, David Taylor, Hans ter Steege, John Terborgh, Armando Torres-Lezama, John Tshibamba Mukendi, Darlington Tuagben, Peter van de Meer, Geertje van der Heijden, Peter van der Hout, Mark van Nieuwstadt, Bert van Ulft, Rodolfo Vasquez Martinez, Ronald Vernimmen, Barbara Vinceti, Simone Vieira, Ima Celia Guimaries Vieira, Emilio Vilanova Torre, Jason Vleminckx, Lee White, Simon Willcock, Mathew Williams, John T. Woods, Tze Leong Yao, Ishak Yassir, Roderick Zagt, Lise Zemagho

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Validation of a New Saliva Test for Helicobacter pylori Infection by OF Bathe, AJ Rae, P Zetler, IGM Cleator

“…The saliva test was determined to be 80% sensitive and 80% specific for H pylori infection when the cut-off for a positive test was 0.3 ELISA U/mL. …”
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