PReventing Idiopathic SCOliosis PROgression (PRISCOPRO): A protocol for a quadruple-blinded, randomized controlled trial comparing 3D designed Boston brace to standard Boston brace... by Elias Diarbakerli, Anastasios Charalampidis, Allan Abbott, Paul Gerdhem

“…Treatment strategies aim to halt progression of the curve. Patients are treated mainly with thoracolumbosacral orthosis (TLSO) if indicated. …”
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The Efforts to Implement a Malaria Elimination Strategy in The Highly Endemic Malaria Region of Papua Province, Indonesia by Erni Juwita Nelwan

“…The authors explored various factors, including the prevalence of malaria, patient characteristics, history of malaria exposure, housing and environmental conditions, as well as malaria prevention measures among the study participants. …”
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One-Year Review Of Reduced Fetal Movements In Izzat Ali Shah MCH Center: A Predictor Of Poor Perinatal Outcome by Humera Rani, Gulwish Salahuddin, Ayesha Naz, Noreen Majeed, Faiza Safdar, Shazia Rafique

“…Results: Out of a total of 160 patients, 144 had alive and stable babies. Regarding the age group, out of 160, six patients were teenagers (3.75%), 98 (61.25%) were between 20-30 years, and 55(34.3%) were in the age group of 30-40 years. …”
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Nutritional intake of micronutrient and macronutrient and type 2 diabetes: machine learning schemes by Mohammad Rashidmayvan, Amin Mansoori, Elahe Derakhshan-Nezhad, Davoud Tanbakuchi, Fatemeh Sangin, Maryam Mohammadi-Bajgiran, Malihehsadat Abedsaeidi, Sara Ghazizadeh, MohammadReza Mohammad Taghizadeh Sarabi, Ali Rezaee, Gordon Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…For ten years (until 2020), the participants in the study were monitored to determine the incidence of T2D. …”
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The Impact of Online Interactive Platform Services on Oral Health Behaviors in Older Adults With Mild Cognitive Impairment: Protocol for a Randomized Controlled Trial by Yin Q, Chai Z, Tao B, Liu P, Luo Y, Zhao Q, Yang B

“…The participants will be randomly assigned to two groups. …”
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METTL14-mediated m6A modification of DDIT4 promotes its mRNA stability in aging-related idiopathic pulmonary fibrosis by Dan Li, Li Qian, Yufeng Du, Lifang Liu, Ziyue Sun, Yongkang Han, Xiangrui Guo, Chao Shen, Zheng Zhang, Xuejun Liu

“…Three-milliliter venous blood was collected from IPF patients and healthy controls. MeRIP-seq and RNA-seq were utilized to investigate differential m6A modification. …”
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Association of outpatient use of renin–angiotensin–aldosterone system blockers on outcomes of acute respiratory illness during the COVID-19 pandemic: a cohort study by Molly Moore Jeffery, Lucas Oliveira J e Silva, Fernanda Bellolio, Nathan W Cummins, Timothy M Dempsey, Vesna D Garovic, Andrew Limper

“…Objectives Evaluate the associations between patients taking ACE inhibitors and angiotensin receptor blockers (ARBs) and their clinical outcomes after an acute viral respiratory illness (AVRI) due to COVID-19.Design Retrospective cohort.Setting The USA; 2017–2018 influenza season, 2018–2019 influenza season, and 2019–2020 influenza/COVID-19 season.Participants People with hypertension (HTN) taking an ACEi, ARB or other HTN medications, and experiencing AVRI.Main outcome measures Change in hospital admission, intensive care unit (ICU) or coronary care unit (CCU), acute respiratory distress (ARD), ARD syndrome (ARDS) and all-cause mortality, comparing COVID-19 to pre-COVID-19 influenza seasons.Results The cohort included 1 059 474 episodes of AVRI (653 797 filled an ACEi or ARB, and 405 677 other HTN medications). 58.6% were women and 72.9% with age ≥65. …”
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Efficacy and Safety of Mesenchymal Stem Cells in Treatment of Complex Perianal Fistulas: A Meta-Analysis by Fang Cheng, Zhong Huang, Zhi Li

“…The adipose-derived MSC group can obtain higher HR than the control group (OR=2.29; 95% CI 1.38, 3.79; P=0.001). …”
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A qualitative study of community perceptions and practices relating to blood donation in Cameroon by Solange Dabou, Wilfred Ngwa, Ngo Valery Ngo, Constantine T Asahngwa, Ghyslaine Bruna Djeunang Dongho, Regina Sinsai, Evrard Kepgang, Odette D Kibu, Ronald Mbua Gobina, Denis Alemka Foretia

“…Introduction Blood and blood products are essential for patients in need of transfusion therapy, especially those undergoing surgical procedures, childbirth and other injuries. …”
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Identifying factors that underpin student decisions to pursue the Doctor of Pharmacy degree at Atlantic Canadian Universities: Protocol for a mixed methods study. by Tiffany A Lee, Amit Sundly, Stephen D Coombs, Gerald J Galway

“…Semi-structured interviews with a sample of 12 to 15 participants will be conducted to further understand and explain the quantitative results. …”
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Comparative Evaluation of Implant-Protected Occlusion in Partially Edentulous Fixed Restoration Using Qualitative and Quantitative Assessment – A Prospective Clinical Trial by Ramesh Chowdhary, S Bukkapatnam

“…Materials and Methods: A total of 20 patients in the age group of 25–61 yrs participated in this study. …”
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Effects of an Aquatic Physical Exercise Program on Ventilatory Parameters in People with Parkinson’s Disease by Bruna Yamaguchi, Dielise Debona Iucksch, Luis Henrique Paladini, Vera Lúcia Israel

“…., walking difficulties) and the patients’ perception of fatigue. The objective of this study was to analyze the effects of an aquatic physical exercise intervention program on ventilatory parameters, perception of fatigue, and gait capacity in participants with PD. …”
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Investigation on the effectiveness of progranulin as a novel predictive biomarker for allergic disorders by Nisreen Waleed Mustafa, Zaid Nabeel Elia, Abeer Mansour Abdel Rasool, Sanaria Fawzi Jarjes, Salam Farid Nawara, Shakhawan Hamid

“…Patients were divided into two groups, 38 were classified as having allergies related to the respiratory system and 46 with allergies related to the skin, based on their clinical diagnosis. …”
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Machine learning prediction of anxiety symptoms in social anxiety disorder: utilizing multimodal data from virtual reality sessions by Jin-Hyun Park, Yu-Bin Shin, Dooyoung Jung, Ji-Won Hur, Seung Pil Pack, Heon-Jeong Lee, Hwamin Lee, Chul-Hyun Cho, Chul-Hyun Cho

“…This study aimed to develop ML algorithms to predict the upper tertile group of various anxiety symptoms based on multimodal data from virtual reality (VR) therapy sessions for social anxiety disorder (SAD) patients and to evaluate their predictive performance across each data type.MethodsThis study included 32 SAD-diagnosed individuals, and finalized a dataset of 132 samples from 25 participants. …”
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Consensus on rapid screening for prodromal Alzheimer’s disease in China by Yao Lu, Ying Wang, Jianping Jia, Qihao Guo, Ya Miao, Lin Huang, Xiaochun Chen, Qinjie Li, Fengfeng Pan, Liang Cui, Tianlu Chen, Yatian Li, Jingnan Wu

“…The supportive evidence and grades of recommendations are based on a systematic literature review and focus group discussion. National meetings were held to allow participants to review, vote and provide their expert opinions to reach a consensus. …”
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Identification of Health Needs in Ukrainian Refugees Seen in a Primary Care Facility in Tenerife, Spain by Willian-Jesús Martín-Dorta, Cristo-Manuel Marrero-González, Eva-Lourdes Díaz-Hernández, Pedro-Ruymán Brito-Brito, Domingo-Ángel Fernández-Gutiérrez, Oxana-Migalievna Rebryk-De Colichón, Ana-Isabel Martín-García, Estrella Pavés-Lorenzo, María-Candelaria Rodríguez-Santos, Juan-Francisco García-Cabrera, Janet Núnez-Marrero, Alfonso-Miguel García-Hernández

“…Results: The sample comprised 59 individuals (45.4% of all patients seen). Eight participants from five family groups took part in the focus group. …”
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The efficacy of a low-dose combination of febuxostat and benzbromarone versus each drug used alone for the treatment of gout by Caiyu Zheng, Caiyu Zheng, Qingwen Tong, Qingwen Tong, Zhijun Zhang, Chunmei Lin, Zhiyi Wang, Dongshu Kang, Yanmei Lin, Jianqing Tian

“…The analysis of medication Treatment effects, Period effects and Patient-Within-Sequence effects for different treatment options was performed by cross-test ANOVA.ResultThe cross-trial analysis revealed no significant differences in the magnitude of uric acid decline among the three groups after treatment. …”
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Assessing the Comparative Efficacy and Safety of Warfarin and Rivaroxaban for Cancer Associated Thrombosis: Experience From a Resource Limited Setting by Abel Tenaw Tasamma, Tsegab Alemayehu Bukate, Abdulrahim Mehadi, Bereket Tagesse Handiso, Beniam Yohannes Kassa, Eman Omer Hassen, Zekarias Seifu Ayalew, Dawit Habtie Tegegne, Gebeyehu Tessema Azibte, Tigest Abebaw Zewdie, Tinsaye Zergaw Shihur, Yonas Degelo Geremamo, Yeabsira Dessalegne Mesfin, Rediet M. Alemayehu, Amanuel Kassu Asefa, Fozia Abdela, Addisu Melkie

“…The Cox regression model was used to compare the outcome of the two groups. The baseline mean (standard deviation) age of the patients was 48.4 (15.0) and 140 (69.7%) of them were female. 41.3% of the participants had one or more comorbidities, and the most common types of cancer were gynecologic (28.9%), hematologic (21.4%), and intra‐abdominal (16.9%). …”
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Clinical Outcomes of Intrauterine Insemination for Male Infertility in Brunei Darussalam by Aeryza Sufiri, Rehana Rehman, Faiza Alam

“… Objectives: This study aims to evaluate the factors influencing the success of Intrauterine insemination (IUI) in infertile patients due to male causes in Brunei Darussalam. Methodology: Pre-diagnosed male infertility patients of all ages were included in this retrospective cohort analysis from the “Raja Isteri Pengiran Anak Saleha (RIPAS) Hospital's” Brunei Darussalam between January 2015 and December 2020. …”
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Exploring the experiences of healthcare professionals in South Africa and Uganda around communicating with children about life-threatening conditions: a workshop-based qualitative... by Sue Ziebland, Julia Ambler, Julia Downing, Alan Stein, Elizabeth Namukwaya, Elizabeth Nabirye, Louise Walker, Elizabeth Rapa, Jeffrey R Hanna, Louise J Dalton, Teresa Pollard, Stephanie Santos-Paulo, Yasmin Gogay, David Kavuma, Ruth Mary Kemigisha, Juliet Namyeso, Tracey Brand, Beverley G Neethling

“…Objectives This study aimed to explore how published communication frameworks could be amended to ensure applicability and cultural appropriateness for professionals to support family-centred conversations by investigating’ healthcare professionals’ (1) experiences of providing support to families when a caregiver or a dependent child (<18 years old) has a life-threatening condition, (2) perceived challenges for caregivers and healthcare professionals in communicating with children about illness, (3) perceptions of how clinicians could be equipped to facilitate conversations between caregivers and children about an adult or the child’s own life-threatening condition and (4) suggestions for amendments to previously published guidelines to ensure cultural relevance in South Africa and Uganda.Design A qualitative study involving two 2-day workshops with embedded focus group discussions, break out rooms and consensus discussions.Setting Health and social care and third sector organisations in South Africa and Uganda.Participants Thirty-two professionals providing care to families affected by life-threatening conditions in South Africa or Uganda who were aged 18 years or older and able to converse in English.Results Participants identified obstacles to having conversations with caregivers about children and to telling children about serious illness during consultations. …”
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