Investigating the effectiveness of ailurophobia treatment using virtual reality technique compared to metacognitive therapy: a randomized clinical trial by Alireza Ebrahimi, Farzad Akbarzadeh, Negar Asgharipour, Razie Salehabadi, Malihe Arjamandi

“…Methods The present study was a Randomized Clinical Trial study that was conducted on 28 patients with Ailurophobia. Based on simple random sampling, the participants were allocated in two groups: metacognitive intervention and virtual reality intervention. …”
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HER-SAFE study design: an open-label, randomised controlled trial to investigate the safety of withdrawal of pharmacological treatment for recovered HER2-targeted therapy-related c... by Robin Chung, James C Moon, Alexander R Lyon, Charlotte H Manisty, Muhummad Sohaib Nazir, Malcolm Walker, Peter Kellman, Benjamin Dowsing, Daniel Chen, Jessica Artico, Mark Westwood, Hakim-Moulay Dehbi, Rebecca Roylance, Tom Crake, Peter Schmid, Arjun Ghosh, Maria Sol Andres, Joanna Pedra, Orla Worn

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Changes in tear cytokine and lactoferrin levels in postmenopausal women with primary acquired nasolacrimal duct obstruction complicated with obstructed meibomian gland dysfunction by Haili Jin, Xianjie Chen, Feng Ji, Yin Liu, Yonghong Sheng, Guoping Wang, Linfeng Han, Xiaohu Wang, He Ding, Jing Liu, Qingqing Fu

“…The IL-10 and EGF levels were not significantly different among the groups. Conclusion The level of pro-inflammatory factors in the tears of patients with PANDO complicated with OMGD was significantly increased, which is likely to cause further damage to ocular surface. …”
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Evaluation of Childhood Traumas, Depressive Symptoms, and Dissociative Experiences in Tinnitus Cases by Mustafa Altıntaş, Deniz Sarlak, Erdinç Özturk, Osman Celbiş

“…This study aimed to evaluate childhood traumas and dissociative experiences, which may be predisposing factors in patients with tinnitus. Methods: The study included 90 voluntary patients (45 patients with tinnitus and 45 in the control group) aged older than 18 years who applied to the otorhinolaryngology clinic between November 2018 and February 2019 and were diagnosed with subjective tinnitus. …”
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Mixed methods evaluation of the Getting it Right First Time programme in elective orthopaedic surgery in England: an analysis from the National Joint Registry and Hospital Episode... by Stephen Morris, James Mason, Rosalind Raine, Peter Martin, Naomi J Fulop, Elena Pizzo, Andrew Hutchings, Helen Barratt, Jean Ledger, Raj Mehta, Sarah Jasim, Fiona Aspinal, Rafael Gafoor

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Problems And Challenges Of Attendance In Medical Students by Muhammad Khurram

“…Medical training in Large Group Interactive Sessions and Clinical Clerkships is designed to equip students with knowledge, skills, and experience necessary to practice medicine safely and effectively. …”
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Perceptions and reflections of embryo donation recipients: a qualitative follow-up study by Seungho Lee, Salomeh Salari, Mona El-Gayar, Joshua Mangels, Rebecca Flyckt, Jody Madeira, Susan Klock, Steven R Lindheim

“…Interviews were transcribed using Temi software and coding was conducted in accordance with grounded theory methodology by five independent researchers to identify themes.Participants came from three embryo donation programmes across the USA. 28 participants, with an average age of 48 years (range: 34–69), volunteered to participate in interviews from a larger subject group. …”
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Adapting the World Health Organization’s Surgical Safety Checklist to High-Income Settings: A Hybrid Effectiveness-Implementation Trial Protocol by Nathan Turley, MA, MBA, Karolina Kogut, BA, Barbara Burian, PhD, Rachel Moyal-Smith, DrPH, PA-C, James Etheridge, MD, MPH, Yves Sonnay, MScPH, William Berry, MD, MPH, Alan Merry, MD, MBChB, Alexander Hannenberg, MD, Alex B. Haynes, MD, MPH, Roger D. Dias, MD, PhD, MBA, Kathryn Hagen, MD, George Molina, MD, MPH, Lisa Spruce, DNP, RN, Carla Williams, RN, MHSM, Mary E. Brindle, MD, MPH, FRCSC

“…A pre–post intervention design will be used to assess the impact of the modified SSC on surgical processes, team culture, patient experience, and safety. This mixed-methods study includes quantitative and qualitative data derived from surveys, semi-structured interviews, patient focus groups, and SSC performance observations. …”
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Altered brain functional network connectivity and topology in type 2 diabetes mellitus by Weiwei Ni, Weiyin Vivian Liu, Mingrui Li, Shouchao Wei, Xuanzi Xu, Shutong Huang, Lanhui Zhu, Jieru Wang, Fengling Wen, Hailing Zhou

“…Node network topology analysis indicated reduced clustering coefficient, degree centrality, eigenvector centrality, and nodal efficiency in multiple nodes in the T2DM group. MoCA scores positively correlated with clustering coefficient and nodal efficiency in the bilateral precentral gyrus in the T2DM group.DiscussionThis study demonstrated significant abnormalities in connectivity and topology of large-scale brain functional networks in T2DM patients. …”
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The association between serum fructosamine and random spot urine fructose levels with the severity of non-alcoholic fatty liver disease – an analytical cross-sectional study by H Kamuzinzi, M Kgomo, P Rheeder, N Dada, P Bester

“…A secondary objective was to determine the association, if any, between serum transaminases, the aspartate aminotransferase (AST) to platelet ratio index (APRI) score, serum fructosamine and urine fructose in different groups with steatosis. Methods. Using a cross-sectional study design, 65 patients with three different levels of NAFLD, as detected by imaging, were enrolled. …”
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Intraoperative haemodynamic optimisation using the Hypotension Prediction Index and its impact on tissular perfusion: a protocol for a randomised controlled trial by Javier Ripollés-Melchor, Ane Abad-motos, Juan Victor Lorente, Ignacio Jimenez, Alejandra Becerra, Wilbert Wesselink, Francesca Reguant, Irene Mojarro, Maria de los Angeles Fuentes, Elizabeth Agudelo, Francisco Herrero-Machancoses, Paula Callejo, Joan Bosch, Manuel Ignacio Monge

“…All participants will be randomly assigned to a control or intervention group. …”
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Acupuncture as prophylaxis for chronic migraine: a protocol for a single-blinded, double-dummy randomised controlled trial by Claire Shuiqing Zhang, Bin Li, Lin Zeng, Lu Liu, Luo-peng Zhao, Kelun Wang, Jingxia Zhao, Linpeng Wang, Xianghong Jing

“…This study is designed as a single-blinded, double-dummy randomised controlled trial to evaluate the efficacy and safety of acupuncture compared with topiramate in patients with chronic migraine.Methods and analysis A total of 60 participants will be randomly assigned to two different groups. …”
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Efficacy and cost-effectiveness of an ACT and compassion-based intervention for women with breast cancer: study protocol of two randomised controlled trials {1} by Inês A. Trindade, Andreia Soares, David Skvarc, Diogo Carreiras, Joana Pereira, Óscar Lourenço, Filipa Sampaio, Bruno de Sousa, Teresa C. Martins, Paula Boaventura, Joana Marta-Simões, Mind Project Team, Helena Moreira

“…Greater improvements in psychosocial, biological and resource use are expected in the Mind group, when compared to the control group(s). Results will likely support the potential benefits of the Mind programme for breast cancer patients and highlight the clinical relevance of integrative and holistic interventions in oncology. …”
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Investigating the impact of couple counseling based on the CHARMS model on sexual quality of life and marital satisfaction of wives of men suffering from myocardial infarction: a r... by Delniya Ghafuri, Soheila Rabeipoor, Kamal Khademvatani, Samira Barjasteh, Atefeh Yas

“…Sampling was done on a convenience basis. Participants were randomly allocated into two groups: control (50 couples) and intervention (50 couples). …”
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Multi-cancer early detection tests for general population screening: a systematic literature review by Ros Wade, Sarah Nevitt, Yiwen Liu, Melissa Harden, Claire Khouja, Gary Raine, Rachel Churchill, Sofia Dias

“…While some differences were observed by ethnicity, these results should be interpreted with caution as most participants recruited were white and the numbers of participants from other ethnic groups were small. …”
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The Relationship Between LRP-5 and LRP-6 Gene Mutations and Postmenopausal Type 2 Diabetes and Obesity by Jun Li, Ya Li, Yunqiu Lu, Siyuan Li, Yecheng Zhu, Chuanbing Sun, Partab Rai, Xuehai Jia

“…This study aimed to evaluate the polymorphisms in LRP5 and LRP6 genes in postmenopausal patients with T2DM and OB. Methods: Participants were categorized into the Non-T2DM group (n = 53) and the T2DM group (n = 89) based on glycemic levels. …”
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Video Laryngoscopy for Endotracheal Intubation: A Consideration for Manual In-Line Stabilization Without Cervical Collar Versus Full Immobilization by Aramvanitch K, Leela-Amornsin S, Tienpratarn W, Nuanprom P, Aussavanodom S, Yuksen C, Boonsri S, Boonjarus N, Sanepim S

“…Secondary outcomes included attempts, time for successful intubation, and Cormack-Lehane classification.Results: Fifty-six participants were evaluated; 28 were in the full immobilization group, and another 28 were in the MILS without cervical hard collar group. …”
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The Gut Microbiota in Women Suffering from Gestational Diabetes Mellitus with the Failure of Glycemic Control by Lifestyle Modification by Guangyong Ye, Long Zhang, Min Wang, Yunbo Chen, Silan Gu, Keyi Wang, Jianhang Leng, Yujia Gu, Xinyou Xie

“…Our results showed that Blautia, Eubacterium_hallii_group, and Faecalibacterium in the gut microbiota showed significant differences among the normoglycemic mother, GDM1, and GDM2 groups, respectively. …”
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When specific exercise is more effective than medication - Sensorimotor training is currently the most promising option to treat and prevent chemotherapy-induced peripheral neuropa... by Fiona Streckmann, Maryam Balke, Céline Hammadou, Bianca Schmidli, Oliver Faude, Sarah Koch

“…Participants in the intervention groups performed supervised sensorimotor training (SMT) or whole-body vibration training (WBV), twice a week, concomitant to medical therapy. …”
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Sex Differences in Computed Tomography Coronary Stenosis Severity Versus Flow Impairment and Impact on Revascularization, Clinical Events and Health Care Costs: A FORECAST Substudy by Lavinia Gabara, Jonathan Hinton, Mohamed Kira, James Shambrook, Ausami Abbas, Sam Wilding, Jonathon A. Leipsic, Pamela S. Douglas, Nick Curzen

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