The Combination of Ketorolac with Local Anesthesia for Pain Control in Day Care Retinal Detachment Surgery: A Randomized Controlled Trial by Xiaohong Chen, Bingqian Liu, Xiaoling Liang, Jiaqing Li, Tao Li, Yonghao Li, Xiling Yu, Cancan Lyu, Xiujuan Zhao, Silvia Tanumiharjo, Chenjin Jin, Lin Lu

“…All participants underwent conventional local anesthesia while patients in the K group received an extra administration of preoperative ketorolac. …”
Get full text

Variation in Clinical Presentation, Metabolic Profile, Hormonal Parameters and Inflammatory Markers in Polycystic Ovary Syndrome Women with and without Polycystic Ovary Morphology... by Sweekruti Jena, Ipsita Mishra, Anoj Kumar Baliarsinha, Debarchan Jena, Madhumita Debata

“…Materials and Methods: A total of 37 patients had PCOM as per the diagnostic criteria for PCOS (Group 1), while 33 patients did not have PCOM on USG and were designated as Group 2. …”
Get full text

Eccentric strengthening vs. conventional therapy in sub-acute stroke survivors: a randomized controlled trial by Kalthoum Belghith, Kalthoum Belghith, Mustapha Zidi, Lhéo Vincent, Lhéo Vincent, Jean-Michel Fedele, Rayan Bou-Serhal, Wael Maktouf

“…A randomized controlled trial will be conducted, adhering to CONSORT guidelines, with participants assigned to either a Conventional Therapy Group or an Eccentric Training Group. …”
Get full text

Vaginal progesterone as luteal phase support in natural cycle frozen-thawed embryo transfer (ProFET): protocol for a multicentre, open-label, randomised controlled trial by Kenny A Rodriguez-Wallberg, Christina Bergh, Ali Khatibi, Annika Strandell, Mats Brännström, Caroline Stadelmann, Kristbjörg Heiður Olsen, Margareta Kitlinski, Susanne Liffner, Eva Lundborg, Göran Westlander, Gabriella Widlund, Åsa Magnusson

Get full text

BCI-Based Rehabilitation on the Stroke in Sequela Stage by Yangyang Miao, Shugeng Chen, Xinru Zhang, Jing Jin, Ren Xu, Ian Daly, Jie Jia, Xingyu Wang, Andrzej Cichocki, Tzyy-Ping Jung

“…Study results showed evidence that patients in the BCI group achieved larger functional improvements than those in the control group and that the BCI-FES system is effective in restoring motor function to upper extremities in stroke patients. …”
Get full text

The care needs of persons with oropharyngeal dysphagia and their informal caregivers: A scoping review. by Aurora Ninfa, Valeria Crispiatico, Nicole Pizzorni, Marta Bassi, Giovanni Casazza, Antonio Schindler, Antonella Delle Fave

“…<h4>Introduction</h4>Besides affecting physical health, Oropharyngeal Dysphagia (OD) entails limitations in daily activities and social participation for both patients and their informal caregivers. …”
Get full text

Efficacy and safety of Xiongzhitongluo granules in the treatment of acute ischemic stroke: study protocol for a randomized controlled trial by Yunmeng Chen, Jingjing Wei, Xiao Liang, Yue Liu, Lina Miao, Di Zhao, Yunfan Zhang, Hongxi Liu, Yunling Zhang

“…Our team developed Xiongzhitongluo granules specifically for AIS and is conducting a randomized controlled trial (RCT) to validate their effectiveness.Methods and analysisThis multi-center, randomized, double-blind, placebo-controlled clinical trial includes 120 participants randomly allocated to the intervention or placebo group. …”
Get full text

Protocol paper: randomized controlled trial of the smart online-to-offline model development for chronic diseases management through digital health in real world setting by Jae Eun Shin, Juho Choi, Heejung Lee, Suk-Won Lee, Juhwan Oh

“…Participants are randomized into treatment and control arms for each group. …”
Get full text

Alterations in Serum Adropin, Adiponectin, and Proinflammatory Cytokine Levels in OSAS by Hakan Celikhisar, Gulay Dasdemir Ilkhan

“…The mean age of the OSAS patients was 50.9 ± 5.7 years and BMI was 32.4 ± 6.0 kg/m2, and there was no statistically significant difference determined with the control group (49.3 ± 5.8 years and 30.6 ± 5, 6 kg/m2) (p>0.05). …”
Get full text

Price tag of glaucoma care is minor compared with the total direct and indirect costs of glaucoma: Results from nationwide survey and register data. by Petri K M Purola, Joonas Taipale, Saku Väätäinen, Mika Harju, Seppo V P Koskinen, Hannu M T Uusitalo

“…Indirect costs covered premature retirement and productivity losses among participants aged 30-64 years. Glaucoma patients (n = 192) were compared with non-glaucomatous population (n = 6,952).…”
Get full text

Increased Serum Angiotensin II Is a Risk Factor of Nonalcoholic Fatty Liver Disease: A Prospective Pilot Study by Yue Li, Feng Xiong, Wen Xu, Side Liu

“…Patients were divided into two groups (NAFLD group and Control group), and the serum Ang II level, IL-1β, IL-18, and lipids were analyzed. …”
Get full text

Artificial intelligence-assisted clinical decision support for childhood asthma management: A randomized clinical trial. by Hee Yun Seol, Pragya Shrestha, Joy Fladager Muth, Chung-Il Wi, Sunghwan Sohn, Euijung Ryu, Miguel Park, Kathy Ihrke, Sungrim Moon, Katherine King, Philip Wheeler, Bijan Borah, James Moriarty, Jordan Rosedahl, Hongfang Liu, Deborah B McWilliams, Young J Juhn

“…There was no difference in the proportion of duration when patients had well-controlled asthma during the study period between the intervention and the control groups.…”
Get full text

Histopathological and Biochemical Assessment of Neuroprotective Effects of Sodium Valproate and Lutein on the Pilocarpine Albino Rat Model of Epilepsy by Aziza Rashed Al-Rafiah, Khlood Mohammed Mehdar

“…To achieve this aim, fifty rats were randomly divided into five groups. Group I: control, group II: received PLC (400 mg/kg intraperitoneally), group III: received PLC + SVP (500 mg/kg orally), group IV: received PLC + SVP + L (100 mg/kg orally), and group V: received (PLC + L). …”
Get full text

Intraoperative Complications of Cataract Surgery Using Intracameral Illumination in the Elderly over 75 Years by Yu Jeong Kim, Su Jin Park, Jong Yeon Lee, Dae Yeong Lee, Dong Heun Nam

“…A retrospective, consecutive, interventional case series Participants. Two hundred eighty-six eyes of 184 patients older than 75 years who underwent cataract surgery using microscope and intracameral illuminations. …”
Get full text

Effectiveness of progesterone supplementation in women presenting low progesterone levels on the day of frozen embryo transfer: a randomised controlled trial by Quang Thanh Le, Thi Minh Chau Le, Khue Tu Duong, Quoc Anh Nguyen, Phuc Thinh Ong, Thi Hong Nhung Nguyen, Thi Cam Thu Thai, Matheus Roque, Carlo Alviggi

“…After signing the informed consent, participants are randomised into two groups: the study group using vaginal micronised progesterone supplemented with progesterone intramuscular 50 mg per day and the control group using only vaginal micronised progesterone. …”
Get full text

Differences in catheter-related complications to insertion site selection for long peripheral intravenous catheters in antimicrobial therapy: a randomized controlled trial by Linfang Zhao, Xianghong Jin, Xiangyun Li, Chang Liu, Jie Wang, Xiuzhu Cao, Xufen Zeng, Yiyu Zhuang

“…Methods This randomized controlled trial included 90 participants randomly assigned to either the control or experimental group, with 45 patients in each group. …”
Get full text

The Impact of Adequate Selenium Intake on Severity Symptoms and Quality of Life among People with Allergic Rhinitis by Thanyapron Tiyawisutsri, Napassorn Suwanpanyakul, Weeraya Kongkasri, Kamonwan Thongsri, Roger Timothy Callaghan, Alongkote Singhato

“…Results: The participants in InadSe group obtained significantly higher scores in almost all the aspects of the severity of symptoms and quality of life impairment compared with participants in adSe group (P<0.05). …”
Get full text

Demographic clinical trial diversity assessment methods: Use of real-world data by Hua Chen, Nnadozie Emechebe, Sudeep Karve, Leon Raskin, Jailene Leal, Ning Cheng, Wendy Sebby, Kim Ribeiro, Samuel Crawford

“…Diversity in clinical trials is defined by the inclusion of clinical trial participants from various demographic groups that are representative of the broader population impacted by a disease state. …”
Get full text

Acute Effects of Percussive Therapy on the Posterior Shoulder Muscles Differ Based on the Athlete’s Soreness Response by Jack H Trainer, Matthew Pascarella, Ryan W Paul, Stephen J Thomas

“… # Study Design Cross-sectional laboratory study # Methods Fifty-five healthy individuals were assessed on a subjective soreness scale before and after a five-minute percussive therapy session on the dominant arm posterior rotator cuff muscles. Participants with no change or a decrease in muscle soreness were assigned to the positive response group and participants who reported an increase in muscle soreness were assigned to the negative response group. …”
Get full text

Antiamoebic Chemoprophylaxis Using Quinfamide in Children: A Comparative Study by Nicolas Padilla, Rosalinda Diaz, Alfonso Alarcon, Roberto Barreda

“…Those included in the study received a single 4.3-g/kg dose of quinfamide, and we performed PSC on days 5, 6, and 7 following dose administration to examine whether quinfamide had affected the presence of the cysts. The study participants who tested negative for cysts were divided into three groups: Group 1 had 102 patients who underwent quinfamide treatment and three CPS analyses after the 12 months of the study; Group 2 had 98 subjects who underwent the quinfamide treatment and three CPS analyses at months 3, 6, 9, and 12 after their entrance into the study; and Group 3 had 102 patients, who underwent the quinfamide treatment and series of three CPS analyses at months 6 and 12 of the study. …”
Get full text