Development of a machine learning-based prediction model for extremely rapid decline in estimated glomerular filtration rate in patients with chronic kidney disease: a retrospectiv... by Shingo Fukuma, Yukio Yuzawa, Daijo Inaguma, Hiroki Hayashi, Ryosuke Yanagiya, Akira Koseki, Toshiya Iwamori, Michiharu Kudo

“…We aimed to identify clusters of patients with extremely rapid eGFR decline and develop a prediction model using a machine learning approach.Design Retrospective single-centre cohort study.Settings Tertiary referral university hospital in Toyoake city, Japan.Participants A total of 5657 patients with CKD with baseline eGFR of 30 mL/min/1.73 m2 and eGFR decline of ≥30% within 2 years.Primary outcome Our main outcome was extremely rapid eGFR decline. …”
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Adaptive clinical trial of AZD7442 and SARS-CoV-2 vaccination in immunosuppressed patients highly vulnerable to infection with SARS-CoV-2 virus (RAPID-PROTECTION): protocol for a m... by Ernest Choy, Kerenza Hood, Emma Thomas-Jones, Eleanor Barnes, Keith Wilson, Christian H Ottensmeier, Debbie Harris, Adrian Hill, Mark Tuthill, Richard Adams, Catherine Porter, Katie Ewer, Sian Griffin, Rebecca Tangney, Joanne Euden, Shirley Pringle, Lawrence Raisanen, Ruby Ray, Lisette Sheena Nixon, Melanie Varley, Craig Bodman, Paola Cicconi, Vivien Dagley, Steven Knapper

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Impaired Emotion Recognition after Left Hemispheric Stroke: A Case Report and Brief Review of the Literature by Hugo P. Aben, Yael D. Reijmer, Johanna M. A. Visser-Meily, Jacoba M. Spikman, Geert Jan Biessels, Paul L. M. de Kort, PROCRAS Study Group

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Protocol for a multicentre, prospective, open-label, randomised controlled trial to compare PROs and safety outcomes between preoperative and postmastectomy radiotherapy in locally... by Li Zhang, Jiong Wu, Guangyu Liu, Shuang Hao, Jianjing Hou, Changming Zhou, Yifeng Hou, Keda Yu, Zhen Hu, Genhong Di, Zhi Min Shao, Xiaoli Yu

“…Patients will be randomly assigned (1:1) to a preoperative radiotherapy group or a postoperative radiotherapy group. …”
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plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN): a protocol for a prospective diagnostic accuracy study of point-of-care testing in patients suspected of acute... by Thomas R Fanshawe, Philip J Turner, Gail N Hayward, Margaret Glogowska, Alastair D Hay, Michael Moore, Mark Lown, Christopher C Butler, Mandy Wootton, Mark H Wilcox, Jane Freeman, Nicola Kenealy, Valerie Tate, Owain Llion, Rebecca Lowe

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Investigation of the effects of combined exercises and self-management education, with and without functional exercises, on pain and functional outcomes in patients with avascular... by Zohreh Gholami, Seyedeh Tahereh Faezi, Elham Madreseh, Raghad Mimar

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Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer:... by Joachim G J V Aerts, Sjoerd H van der Burg, Martijn P Lolkema, Sai Ping Lau, Freek R van ’t Land, Marjolein Y V Homs, Casper H J van Eijck

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Revealing viral hepatitis epidemiology in the Democratic Republic of Congo: insights from yellow fever surveillance reanalysis by Patrick Mukadi-Kakoni, Yannick Munyeku-Bazitama, Gracia Kashitu-Mujinga, Marguerite Manwana-Pemba, Niclette Zenga-Bibi, Patient Okitale-Talunda, Christelle Mbelu-Kabongo, Fleurette Domai-Mbuyakala, Elisabeth Pukuta-Simbu, Pierre Mutantu-Nsele, Yoshinao Kubo, Sheila Makiala-Mandanda, Steve Ahuka-Mundeke, Koya Ariyoshi, Jean-Jacques Muyembe-Tamfum

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Urinary Sodium Concentration Is an Independent Predictor of All-Cause and Cardiovascular Mortality in a Type 2 Diabetes Cohort Population by Pierre-Jean Saulnier, Elise Gand, Stéphanie Ragot, Lise Bankir, Xavier Piguel, Frédéric Fumeron, Vincent Rigalleau, Jean-Michel Halimi, Richard Marechaud, Ronan Roussel, Samy Hadjadj, SURDIAGENE Study group

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The prevalence and 6-year incidence of myopic tessellation in a Chinese rural adult population: the Handan Eye Study by Caixia Lin, Jian Wu, Kai Cao, Bingsong Wang, Yuxin Fang, Ohno-Matsui Kyoko, Yunyun Sun, Jie Hao, Lixia Ma, Ye Zhang, Qing Zhang, Ningli Wang, the Handan Eye Study Group

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Community pharmacist-and psychologist-led program of neuropsychological screening in the aftermath of the COVID-19 pandemic: A cross-sectional survey by Nicola Luigi BRAGAZZI, Fiorella PALOMBO-FERRETTI, Rocco CARBONE, Tania Simona RE, "Pharmacists- and Psychologists in community pharmacies-led Psychological Screening for Cognitive issues in the aftermath of the COVID-19 pandemic" (PsyChOVID) WORKING GROUP

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A national study of choanal atresia in tertiary care centers in Canada – part I: clinical presentation by Josee Paradis, Agnieszka Dzioba, Hamdy El-Hakim, Paul Hong, Frederick K. Kozak, Lily H. P. Nguyen, Demitri Perera, Evan Jon Propst, Jennifer M. Siu, Monika Wojtera, Murad Husein, National Choanal Atresia Study Working Group

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A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management by Josee Paradis, Agnieszka Dzioba, Hamdy El-Hakim, Paul Hong, Frederick K. Kozak, Lily H. P. Nguyen, Demitri Perera, Evan Jon Propst, Jennifer M. Siu, Monika Wojtera, Murad Husein, National Choanal Atresia Study Working Group

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Increased Early‐Mortality in Children With Solid Tumors During the COVID‐19 Pandemic in a Middle‐Income Country by Oscar Ramirez, Vivian Piedrahita, Santiago Bolivar, Karina Grillo, Adriana Linares, Carlos Pardo, Martha Piña, Amaranto Suarez, Carlos A. Portilla, Jesus Ardila, Viviana Lotero, Luz A. Urcuqui, Angela Trujillo, Patricia Montenegro, Luis E. Bravo, Paula Aristizabal, VIGICANCER Working Group

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Cluster randomised controlled trial of screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the pilot study for the SAFER trial by Martin R Cowie, Stephen Morris, Gregory Lip, Richard J McManus, Stephen Sutton, Jonathan Mant, Simon J Griffin, Sarah Hoare, Jenni Burt, Rachel Johnson, Mark Lown, Alison Powell, Natalie Armstrong, FD Richard Hobbs, Trudie Lobban, Rakesh Narendra Modi, Ben Freedman, David A Fitzmaurice, Stephen Kaptoge, Jenny Lund, Duncan Edwards, Kate Williams, H Thom, Francesco Fusco, Michael J Sweeting, Andrew Dymond, The SAFER Authorship Group

“…An economic evaluation using the pilot data will confirm whether it is plausible that screening might be cost-effective.Ethics and dissemination The London—Central Research Ethics Committee (19/LO/1597) and Confidentiality Advisory Group (19/CAG/0226) provided ethical approval. Dissemination will be via publications, patient-friendly summaries, reports and engagement with the UK National Screening Committee.Trial registration number ISRCTN72104369.…”
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Local Recurrence of Rectal Cancer After Transanal Total Mesorectal Excision and Risk Factors: A Nationwide Multicenter Cohort Study in Japan by Takeru Matsuda, MD, PhD, Ichiro Takemasa, MD, PhD, Hideki Endo, MD, MPH, Shinichiro Mori, MD, PhD, Suguru Hasegawa, MD, PhD, Koya Hida, MD, PhD, Takuya Tokunaga, MD, PhD, Keitaro Tanaka, MD, PhD, Toshiki Mukai, MD, PhD, Jun Watanabe, MD, PhD, Junichiro Kawamura, MD, PhD, Kei Kimura, MD, PhD, Yoshihiro Kakeji, MD, PhD, Masahiko Watanabe, MD, PhD, Seiichiro Yamamoto, MD, PhD, Takeshi Naitoh, MD, PhD, Ta-Ta-Mi study group collaboratives in Japan Society of Laparoscopic Colorectal Surgery

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Implementing a Care Model for Bedridden Stroke Survivors: A Qualitative Study in Northeastern Thailand by Panpanit L, Jongudomkarn D, Doungmungkorn A, Boontoch K, Neelasmith S, Manorat M, Maneerat T

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Barriers to Adherence to Standard of Care in Appalachia: A Qualitative Assessment in Gastrointestinal Cancers by Levy BE, Castle JT, Bardhan R, Dignan M, Bhakta A

“…The purpose of this investigation was to improve understanding of barriers that cancer patients residing in rural areas not served directly by tertiary medical systems must overcome in completing adjuvant therapy.Methods: Participants were recruited from two medical centers: A tertiary care NCI designated Cancer Center and a regional hospital. …”
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Ethical and Bioethical Dilemmas in Paediatric Primary Health Care Setting by José Jesús García Mendiola, Gisselle Chi Gil, Maite Piñeiro Barreiro, Niurka Tamara Callejas Sánchez

“…Medical Ethics gathers a group of principles and standards that rule out the behaviour amongst the health staff and amongst the doctor-patient and doctor-relatives relationship in order to preserve the patient’s health, treatment and rehabilitation. …”
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Using Real‐Time Power BI Formative Feedback to Improve Nurse Anesthesia Students' Clinical Competence: An Educational Intervention by Ali Khalafi, Sajjad Choopani, Nooshin Sarvi‐Sarmeydani, Elham Maraghi

“…Methods This educational intervention was conducted with the participation of nurse anesthesia students who were enrolled into intervention and control groups. …”
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