Trabeculectomy versus stepwise treatment for breaking the attack of acute primary angle closure in patients with long attack duration: study design and protocol for a multicentre r... by Jing Jiang, Qing Zhang, Bo Qu, Chao Dai, Mingguang He, Ye Zhang, Ning-Li Wang, Shuning Li, Guangxian Tang, Su Jie Fan, Zhi Li, Chi Liu, Xinqi Chang, Yanyan Cheng

“…Eligible participants will be identified at either emergency department or glaucoma clinics, then randomised into stepped treatment group or trabeculectomy group using a computer central randomisation service. …”
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Are deprivation-specific cancer survival patterns similar according to individual-based and area-based measures? A cohort study of patients diagnosed with five malignancies in Engl... by Lucy Elliss-Brookes, Aurélien Belot, Matthew Baker, Fiona C Ingleby, Laura M Woods, Iain M Atherton

“…Objective To investigate if measured inequalities in cancer survival differ when using individual-based (‘person’) compared with area-based (‘place’) measures of deprivation for three socioeconomic dimensions: income, deprivation and occupation.Design Cohort study.Setting Data from the Office for National Statistics Longitudinal Study of England and Wales, UK, linked to the National Cancer Registration Database.Participants Patients diagnosed with cancers of the colorectum, breast, prostate, bladder or with non-Hodgkin’s lymphoma during the period 2008–2016.Primary and secondary outcome measures Differentials in net survival between groups defined by individual wage, occupation and education compared with those obtained from corresponding area-level metrics using the English and Welsh Indices of Multiple Deprivation.Results Survival was negatively associated with area-based deprivation irrespective of the type analysed, although a trend from least to most deprived was not always observed. …”
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The Effect of Whey Protein Consumption on Postprandial Glucose, Insulin and Incretin Responses in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Acute-Term... by Zahra Salimi, Maryam Asadi, Anahita Mansoori

“…Results: The pooled analysis of the included trials indicated a significant reduction in the mean of glucose in the area under the curve [standard mean difference (SMD)=-1.295, 95% CI: -1.878 to -0.712, P<0.001] and also an increase in the mean of insulin, gastric inhibitory polypeptide (GIP) and glucagon‐like peptide‐1 (SMD=0.562, 95% CI: 0.303 to 0.822, P<0.001, SMD=0.349, 95% CI: 0.074 to 0.624, P=0.013 and SMD=0.439, 95% CI: 0.154 to 0.724, P=0.003, respectively) in participants who consumed whey protein compared with the control group. …”
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Investigating the relationship between thought interference, somatic passivity and outcomes in patients with psychosis: a natural language processing approach using a clinical reco... by Robert Stewart, Anna Kolliakou, Jyoti Sanyal, Rashmi Patel, Thibault Thierry Magrangeas

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Safety and effectiveness of appropriately and inappropriately dosed rivaroxaban or apixaban versus warfarin in patients with atrial fibrillation: a cohort study with nested case–co... by Luis Alberto García Rodríguez, Pareen Vora, Luke Roberts, Gunnar Brobert, Samuel Fatoba, María Eugenia Sáez, Antonio González-Pérez

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Association between terminal pleural elastance and radiographic lung re-expansion after therapeutic thoracentesis in patients with symptomatic pleural effusion: a post-hoc analysis... by Fabien Maldonado, Michael Lester, Otis B Rickman, Lance J Roller, Sameer K Avasarala, James M Katsis, Robert J Lentz

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Association between chiropractic spinal manipulative therapy and benzodiazepine prescription in patients with radicular low back pain: a retrospective cohort study using real-world... by Jeffery A Dusek, Robert James Trager, Zachary A Cupler, Kayla J DeLano, Jaime A Perez

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Risk factors for thromboembolic and bleeding events in anticoagulated patients with atrial fibrillation: the prospective, multicentre observational PREvention oF thromboembolic eve... by Raffaele De Caterina, Kurt Huber, Richard Schilling, Miklos Rohla, Thomas W Weiss, Ladislav Pecen, Giuseppe Patti, Jolanta M Siller-Matula, Renate B Schnabel, Dipak Kotecha, Markus Lucerna, Paulus Kirchhof

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Initial treatment with a single capsule containing half-dose quadruple therapy vs standard-dose dual therapy in hypertensive patients (QUADUAL): a randomized, blinded, crossover tr... by Xiexiong Zhao, Tao Liu, Qiong Yang, Guoping Yang, Xingli Li, Xiaohong Tang, Jingle Li, Zhongshu Liang, Anying Li, Lixiong Zeng, Juan Wen, Xiaoyan Wang, Liping Peng, Wenjuan Wang, Jingjing Cai, Ye Chen, Miao Huang, Ruixuan Li, Ru Fu, Lin Zhao, Xiaogang Li, Weihong Jiang

“…Results A total of 90 eligible participants were randomized between July 13, 2022, and April 20, 2023. …”
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The effect of knowledge, attitude, and practice model-based health education on psychological well-being and self-efficacy of patients with concurrent cerebrovascular stenosis and... by Qiyu Zhou, Yuli Qian, Dan Zhang, Huan Xu, Bei Yuan, Wenfeng Tian, Qiong Li

“…Patients were randomly assigned to either a control group (n = 30) or an intervention group (n = 30). …”
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Does Treatment with Sodium-Glucose Cotransporter-2 Inhibitors Affect Adherence to International Society Criteria for Diabetic Ketoacidosis in Adult Patients with Type 2 Diabetes? A... by Aongus O’Brolchain, Joshua Maletsky, Ibrahim Mian, Serena Edwards

“…Patients were divided into two groups by treatment with SGLT2i at the time of diagnosis. …”
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Impact of a phone call with a medical student/general practitioner team on morbidity of chronic patients during the first French COVID-19 lockdown (COVIQuest): a cluster randomised... by Bruno Giraudeau, Estelle Boivin, Vincent Camus, Agnes Caille, Olivier Saint-Lary, Jean-Pierre Lebeau, Stéphanie Sidorkiewicz, Denis Pouchain, Maeva Jego, Sophie Sun, Denis Angoulvant, Wissam El-Hage, Sébastien Bruel, Clarisse Dibao-Dina, Julie Léger, Isabelle Ettori-Ajasse, Juliette Chambe, Karim Abou-Mrad-Fricquegnon, Baptiste Motte, Benoit Chiron, Cam-Anh Khau, Tiphanie Bouchez, Maria Ghali, Leslie Guillon-Grammatico, Emeline Laurent, Rémy Boussageon

“…Clusters were GPs from eight French regions.Participants Patients ≥70 years old with chronic CVD (COVIQuest_CV subtrial) or ≥18 years old with MHD (COVIQuest_MH subtrial).Interventions A standardised GP-initiated phone call aiming to evaluate patients’ need for urgent healthcare, with a control group benefiting from usual care (ie, the contact with the GP was by the patient’s initiative).Main outcome measures Hospital admission within 1 month after the phone call.Results In the COVIQuest_CV subtrial, 131 GPs and 1834 patients were included in the intervention group and 136 GPs and 1510 patients were allocated to the control group. …”
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Sensitivity and specificity of the Patient Health Questionnaire (PHQ-9, PHQ-8, PHQ-2) and General Anxiety Disorder scale (GAD-7, GAD-2) for depression and anxiety diagnosis: a cros... by David Villarreal-Zegarra, Juan Carlos Bazo-Alvarez, Juan Barrera-Begazo, Sharlyn Otazú-Alfaro, Nikol Mayo-Puchoc, Jeff Huarcaya-Victoria

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Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraep... by Fei Chen, Jinghe Lang, Peter Hillemanns, Youzhong Zhang, Zoltán Novák, Long Sui, Ling Han, Christian Dannecker, Ctirad Mokráš, Zhixue You

“…The aim is to include at least 384 patients, which will be randomised to either Cevira or placebo group (2:1). …”
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Transauricular vagus nerve stimulation in preventing post-traumatic stress disorder in emergency trauma surgery patients in China: a study protocol for a multicenter, double-blind,... by Jun Zhang, Xin Yu, Gang Chen, Yu Li, Qi-Hong Shen, Xinru Lin, Tieshuai Liu, Yunyun Yu, Jingwen Liang

“…Introduction The incidence of post-traumatic stress disorder (PTSD) in emergency trauma surgery patients is 24%, emphasising the urgent need for effective early interventions and treatments. …”
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Nissen-Sleeve procedure versus laparoscopic Roux-en-Y gastric bypass in patients with morbid obesity and gastro-oesophageal reflux disease: protocol for a non-inferiority randomise... by Jan A Apers, Martin Dunkelgrun, Ivonne Leeuwenburgh, Judith W H 't Hart, Bo J Noordman, Laser U Biter

“…For patients with a contraindication for LRYGB or a strong preference for LSG, the Nissen-Sleeve procedure may be a viable new option. …”
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Activities of daily living after surgery among older patients with gastrointestinal and hepatobiliary-pancreatic cancers: a retrospective observational study using nationwide healt... by Ayako Okuyama, Takahiro Higashi, Hisashi Kosaka, Asao Ogawa, Masaki Kaibori

“…This study aimed to evaluate activities of daily living (ADLs) after oncological surgery in patients with gastrointestinal and hepatobiliary-pancreatic cancers by age groups in Japan.Design Retrospective observational study using health services utilisation data from 1 January 2015 to 31 December 2016.Setting Data for patients with gastrointestinal and hepatobiliary-pancreatic cancers diagnosed in 2015 from 431 hospitals nationwide in Japan.Participants Patients who underwent endoscopic submucosal dissection (ESD), endoscopic mucosal resection (EMR) and laparoscopic or open surgery were included.Outcome measures The proportion of ADL decline at discharge, death and unexpected readmission within 6 weeks postsurgery was calculated by age groups (40–74, 75–79 and ≥80 years).Results Data for 68 032 patients were analysed. …”
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Perceived stress, trust, safety and severity of SARS-CoV-2 infection among patients discharged from hospital during the COVID-19 pandemic’s first wave: a PREMs survey by Henk Verloo, Eric Bonvin, Nadine Tacchini-Jacquier, Sevrine Monnay

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Study protocol for virtual leisure investigating the effect of virtual reality-delivered stress reduction, entertainment and distraction on the use of coercion and need-based medic... by Julie Midtgaard, Lars Clemmensen, Louise Birkedal Glenthøj, Gry Jørgensen, Kristina Ballestad Gundersen, Lisa Charlotte Smith, Stephane Bouchard, Christina Plambøck Thomsen, Louise Turgut

“…Feasibility and acceptability will be explored with qualitative interviews supplemented with non-participant observations and focus groups. The study began on 1 January 2023, and we expect to complete data collection by 31 December 2024.Ethics and dissemination The study is registered at Danish Data Protection Agency (j.no P-2022-466) and is approved by the Committee on Health Research Ethics of the capital region of Denmark (j.no 22013313). …”
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Adaptation and Feasibility Study of a Digital Health Program to Prevent Diabetes among Low-Income Patients: Results from a Partnership between a Digital Health Company and an Acade... by Valy Fontil, Kelly McDermott, Lina Tieu, Christina Rios, Eliza Gibson, Cynthia Castro Sweet, Mike Payne, Courtney R. Lyles

“…The majority of focus group participants were receptive to the program. …”
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