Survival in patients with CKD 3–5 after 12 months of exercise training – a post-hoc analysis of the RENEXC trial by Sara Denguir, Matthias Hellberg, Martin Almquist, Naomi Clyne

“…Patients were categorized into five groups: improved ≥ 5%, unchanged, deteriorated ≥ 5%, non-completers, missing data. …”
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Early prediction of in-hospital mortality in patients with congestive heart failure in intensive care unit: a retrospective observational cohort study by Tao Huang, Rui Yang, Jun Lyu, Didi Han, Fengshuo Xu, Shuai Zheng, Luming Zhang, Haiyan Yin

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The efficacy of sodium-glucose transporter 2 inhibitors in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis by Hongsheng Li, Yanli Hou, Wenyong Xin, Lina Ding, Ying Yang, Yikun Zhang, Wenqi Wu, Zhibin Wang, Wenyu Ding

“…Eleven articles (n = 805 patients with NAFLD) were included in this study. Of these, 408 participants received SGLT-2 inhibitors, while 397 participants were in the control group. …”
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Considering Psychosocial Factors When Investigating Blood Pressure in Patients with Short Sleep Duration: A Propensity Score Matched Analysis by Ningjing Qian, Dandan Yang, Huajun Li, Siyin Ding, Xia Yu, Qingqiu Fan, Zhebin Yu, Shenfeng Ye, Hualiang Yu, Yaping Wang, Xiaohong Pan

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The Significance of a Cerebrovascular Accident Outcome Prediction Model for Patients, Family Members, and Health Care Professionals: Qualitative Evaluation Study by Corinne G Allaart, Sanne van Houwelingen, Pieter HE Hilkens, Aart van Halteren, Douwe H Biesma, Lea Dijksman, Paul B van der Nat

“…MethodsWe designed a mock-up version, including visualizations, based on our recently developed prediction model. We conducted focus groups with CVA patients and informal caregivers, and separate focus groups with health care professionals (HCPs). …”
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Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional study by Feixia Ni, Tingting Cai, Tingting Zhou, Changrong Yuan

“…Results: A total of 640 patients participated in this study. The findings revealed three subgroups in terms of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: low physical-social-cognitive function, high physical-low cognitive function, and high physical-social-cognitive function. …”
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Assessment of Home Isolation Measures and Factors Associated with Adherence Among Patients During the Pandemic in Nepal: A CrossSectional Study by Lisasha Poudel, Bikram Adhiakri1 , Deekshya Neupane, Pranita Maharjan, Tek Bahadur, Pramita Shrestha, Rashmi Maharjan, Nishan Katuwal, Brish Bahadur Shahi, 3akhat Bhandari, Rajeev Shrestha, Biraj Man Karmacharya, Archana Shrestha

“…Conclusion State and local authorities are recommended to develop specific measures to enhance the knowledge and practice of the participant groups likely to exhibit low adherence to home isolation measures.   …”
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Differential risk of cardiovascular complications in patients with type-2 diabetes mellitus in Ghana: A hospital-based cross-sectional study. by Christian Obirikorang, Evans Asamoah Adu, Anthony Afum-Adjei Awuah, Samuel Nkansah Darko, Frank Naku Ghartey, Samuel Ametepe, Eric N Y Nyarko, Enoch Odame Anto, William Kwame Boakye Ansah Owiredu

“…<h4>Results</h4>The study identified three groups in female patients according to body mass index, relative fat mass, glycated hemoglobin, and triglyceride-glucose index. …”
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The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pil... by Mia T. Minen, Erin K. Waire, John Torous, Jessica Fishman, Richard B. Lipton, Scott W. Powers

“…We also compared our adherence data at 90-days (a secondary endpoint to assess the durability of the effect) with adherence data from similar published studies without the adherence-enhancing package. We enrolled 26 participants (n = 15 low intensity group, n = 11 high-intensity group). …”
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Comparison of two bolus doses of dexmedetomidine for prophylaxis against postoperative nausea and vomiting in highly susceptible patients: A randomized controlled trial by Maha Mohamed Ismail Youssef, Amr Raafat Mahmoud Seif, Kareem Nagy Abbass Ahmed, Ghada Abo Bakr, Gihan Mohamed Obayah, Mohamed Ramadan Ahmed Mohamed

“…Materials and Methods: This randomized, double-blinded trial was conducted on 180 patients undergoing total thyroidectomy. Participants were randomly divided equally into three groups. …”
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The Effect of Lower-Limb Exercise on Pain Management of the Patients Undergoing Posterior Lumbar Fusion Surgery: A Retrospective Case-Control Study by Tong Wu, Yong Ye

“…After surgery, some patients took celecoxib for analgesia (celecoxib group, 200 mg/day) while the others took celecoxib together with lower-limb exercise (combined group, celecoxib-200 mg/day). …”
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Spirituality-based palliative care education on quality of life, death anxiety, and resilience of heart failure patients: Randomized controlled clinical trial by Roghayeh Balaghi Inaloo, Mostafa Bijani, Leila Nikrouz, Azizallah Dehghan, Abdulhakim Alkamel, Ali Taghinezhad, Zahra Khiyali

“…Objectives: This study investigated the effects of spirituality-based palliative care education on quality of life, death anxiety, and resilience among heart failure patients in southern Iran. Methods: This investigation employed a randomized controlled clinical trial design without blinding, incorporating both experimental and control groups. 80 patients who were randomly assigned to intervention and control groups (40 patients per group). …”
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Changes of Cell Adhesion Molecules and T Cell Subset Populations in Acute Myeloid Leukemia Patients Undergoing Intravenous Administration of Cytarabine Supplemented with Idarubicin by Jinhua Piao, Didi Wang, Siying Pei, Tangdong Ge, Jing Li, Pengxia Zhang

“…Methods. A total of 88 AML patients eligible for inclusion and exclusion criteria participated in the study and were randomly assigned into the control group (n = 44) in which the patients received intravenous administration of cytarabine and daunorubicin and the study group (n = 44) in which the patients received intravenous administration of cytarabine and idarubicin. …”
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The potential of an integrated pharmaceutical care model with telepharmacy in adherence and knowledge about pharmacological treatment in patients with mental disorders: A clinical... by Núbia Cristina Burgo Godoi de Carvalho, Ana Carolina Figueiredo Modesto, Mércia Pandolfo Provin

“…A parallel randomized clinical trial was conducted with a two-arm study in two Psychosocial Care Centers located in a state capital in Brazil. Participants in the intervention group received a comprehensive pharmaceutical care model that included attitudinal, technical, and educational interventions, while the control group received standard routine care. …”
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Decreased Gray Matter Volume in the Frontal Cortex of Migraine Patients with Associated Functional Connectivity Alterations: A VBM and rs-FC Study by Zhijian Cao, Wenjing Yu, Zhengxiang Zhang, Maosheng Xu, Jiangnan Lin, Luping Zhang, Wenwen Song

“…Methods. Thirty-four patients with a history of migraine without aura presenting during the interictal period (MwoA-DI), 10 patients with migraine without aura presenting during the acute attack (MwoA-DA), and 32 healthy controls (HCs) were recruited in this study. …”
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Efficacy of linaclotide in combination with polyethylene glycol for bowel preparation in Chinese patients undergoing colonoscopy polypectomy: protocol for a randomised controlled t... by Jing Xu, Ping-ping Chen, Dong Chen, Hui-Ying Zhao, Xiao-Feng Cai, Xiao-Bin Wang, Chao-Xu Liu

“…A total of 422 participants will be randomly assigned in a 1:1 ratio to either the intervention group (2 L PEG combined with 580 µg linaclotide) or the control group (4 L PEG). …”
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Comparison of the Response to Pulpal Sensibility Tests in Well-Controlled and Uncontrolled Type II Diabetes Mellitus Patients: A Cross-Sectional Study by Fatemeh Owlia, Faezeh Zarezadeh, Sara Jambarsang, Maryam Kazemipoor

“…At last, 51 diabetic patients were allocated to each group of well-controlled (HbA1C < 7) and uncontrolled (HbA1C ≥ 7). …”
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Effects of Pioglitazone on Asymmetric Dimethylarginine and Components of the Metabolic Syndrome in Nondiabetic Patients (EPICAMP Study): A Double-Blind, Randomized Clinical Trial by Pedram Shokouh, Adel Joharimoghadam, Hamidreza Roohafza, Masoumeh Sadeghi, Allahyar Golabchi, Maryam Boshtam, Nizal Sarrafzadegan

“…The present trial aimed to investigate the effects of pioglitazone on the serum level of asymmetric dimethylarginine (ADMA), a marker of endothelial function, and some indices of inflammation and glucose and lipid metabolism in nondiabetic metabolic syndrome patients. 104 eligible participants (57% female; age between 20 and 70) were enrolled in a double-blind placebo-controlled trial and were randomized to receive either pioglitazone (uptitrated to 30 mg/day) or matching placebo for 24 weeks. …”
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Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus by Haoyi Yang, Yuwen Zhang, Yuxin Hong, Yuan Wei, Yuning Zhu, Lei Huang, Yuanxun Yang, Runbin Sun, Runbin Sun, Runbin Sun, Juan Li, Juan Li, Juan Li

“…ContextAs a novel SGLT1 inhibitor, SY-009 has been preliminarily confirmed in a phase Ib clinical study for its ability to reduce postprandial blood glucose in patients with type 2 diabetes mellitus (T2DM). However, the effects of SY-009 on human plasma metabolomics are still unknown.ObjectiveThis study aimed to explore the effects of SY-009 on plasma metabolomics in patients with T2DM and the potential metabolic regulatory mechanism involved.Study designIn the phase Ib study, a total of 50 participants with T2DM were enrolled and randomly assigned to the 0.5 mg BID, 1 mg BID, 2 mg BID, 1 mg QD, and 2 mg QD dose groups, with a 4:1 random allocation within each group to receive either the SY-009 capsule or placebo. …”
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Trazodone effectiveness in depression: impacts of trazodone extended release vs SSRIs on the health status and quality of life of patients with major depressive disorder by Marcin Siwek, Adrian Andrzej Chrobak, Anna Julia Krupa, Aleksandra Gorostowicz, Andrzej Juryk, Dominika Dudek

“…More participants reported mixed changes in their health status and HRQoL in the SSRI group than the trazodone XR group.DiscussionHealth status and HRQoL improved in both treatment arms, with preferable scores in trazodone XR vs. …”
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