Parallel-group, randomised, controlled, non-inferiority trial of high-flow nasal cannula versus non-invasive ventilation for emergency patients with acute cardiogenic pulmonary oed... by Apichaya Monsomboon, Onlak Ruangsomboon, Nattakarn Praphruetkit

“…Therefore, we planned this study to investigate the effects of HFNC compared with NIPPV for emergency patients with ACPE.Methods and analysis In this single-centred, non-blinded, parallel-group, randomised, controlled, non-inferiority trial, we will randomly allocate 240 patients visiting the emergency department with ACPE in a 1:1 ratio to receive either HFNC or NIPPV for at least 4 hours using computer-generated mixed-block randomisation concealed by sealed opaque envelopes. …”
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Do cognitive bias and heuristics influence improvement in knee pain in patients with knee osteoarthritis treated with open label placebo? The CHIPS study - An exploratory study usi... by Tommy Kok Annfeldt, Elisabeth Ginnerup-Nielsen, Eva Elisabeth Wæhrens, Lene Vase, Lars Erik Kristensen, Tanja Schjødt Jørgensen

“…Results: 103 participants received the questionnaire, and 60 finalised questionnaires were included in the analysis showing that the reduction in pain was associated with the patient-experience and that the affect heuristic acted as an effect modifier. …”
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Fluoxetine for reducing postoperative cognitive dysfunction in elderly patients after total knee replacement: study protocol for a single-centre, double-blind, randomised, parallel... by Yusheng Yao, Hong Ye, Yushan Wu, Daoyi Lin, Lulu Yu, Jiaxin Chen

“…Five hundred elderly patients undergoing unilateral TKA will be randomly assigned to the fluoxetine and placebo groups. …”
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Influence of the metabolic control in patients with type 1 diabetes on their oral health status and the need for orthodontic treatment in a group of Spanish children (aged 6–12 yea... by Adrián Curto, Cristina Gómez-Polo, Daniel Curto, Marta Muñoz-Bruguier, Mari Cruz Lorenzo-Luengo, Javier Montero

“…A total of 260 children with type 1 diabetes (aged between 6 and 12 years) participated. The sample was divided into two study groups based on their metabolic control: good metabolic control (HbA1c < 7%) (n = 130) and poor metabolic control (HbA1c > 7%) (n = 130). …”
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Perception of phage therapy and research across selected professional and social groups in Poland by Maciej Żaczek, Marcin W. Zieliński, Andrzej Górski, Andrzej Górski, Andrzej Górski, Beata Weber-Dąbrowska, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki

“…There is no doubt that in the last 15 years phage therapy has re-emerged from the shadow of antibiotics, from the perspective of both scientists and various patient advocacy groups. Despite some important progress, there is little to no data on phage therapy perceptions in key groups, i.e., patients and their relatives, physicians and anyone who could potentially become infected with antibiotic-resistant bacteria. …”
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Elevation of Circulating miR-210 Participates in the Occurrence and Development of Type 2 Diabetes Mellitus and Its Complications by Xi Chen, Feng Tian, Zhilian Sun, Guoqing Zeng, Ping Tang

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Model of quality of life in a group of people with chronic low back pain by Urszula Ziętalewicz, Kamilla Bargiel-Matusiewicz

“…The present study aimed to test the relationships between the variables in Wilson and Cleary’s QoL model in a CLBP group and to compare them to a nonpain group. Participants and procedure Data were obtained from 177 people with CLBP and 160 nonpain participants. …”
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TEC-ADHERE: Real-World Persistence and Adherence on Dimethyl Fumarate in Patients with Relapsing–Remitting Multiple Sclerosis in the French OroSEP Patient-Support Program by Pierre Labauge, Alain Créange, Thibault Moreau, Jocelyne Nouvet-Gire, Bernard Pedespan, Olivier Heinzlef, Nathalie Texier, Marilyn Gros, Catherine Marti, Marta Ruiz, Mikel Martinez, Giovanni Castelnovo

“…Secondary outcomes included persistence at M1 and M3, adherence at M6 (Girerd questionnaire), anxiety (Generalized Anxiety Disorder Assessment), patient satisfaction at M6 (Treatment Satisfaction Questionnaire for Medication), patient and neurologist satisfaction with OroSEP participation, and adverse events (AEs). …”
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Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study by Manuel R Blum, Patricia M Kearney, Rose Galvin, Christine Baumgartner, Anette Van Dorland, Stephen Byrne, Nicolas Rodondi, Simon P Mooijaart, Carol Sinnott, Rosalinde K E Poortvliet, Jacobijn Gussekloo, David O Riordan, Carole Elodie Aubert, Kieran A Walsh, Robert S Du Puy, J Wouter Jukema, Vera McCarthy, Elaine K Walsh, Tinh-Hai Collet, Olaf M Dekkers

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Gut microbiota and kidney function in autosomal dominant polycystic kidney disease participants in Cameroon: a cross-sectional study by Inès Obolo Nwaga, Victorine Bandolo Nzana, Rhoda Nsen Bughe, Isaac Dah, Cheboh Cho-Fon, Maimouna Mahamat, Emmanuelle Ndjong, Aristide Nono, Jean Claude Mballa, Fon Abongwa Acho, Vicky Ama Moor, Wilfred Fon Mbacham, François Folefack Kaze

“…Lactobacillus abundance was lower in ADPKD participants with more pronounced kidney function decline (CKD G3-5: 0.58 ng/μL) than in those with milder damage and controls (G1-2: 0.64 ng/μL, p = 0.047; controls: 0.71 ng/μL, p = 0.043), while Enterobacteriaceae abundance was greater in ADPKD patients with lower kidney function (CKD G3-5: 78.6 ng/μL) than in those in the other two groups (G1-2: 71.6 ng/μL, p = 0.048; controls: 70.5 ng/μL, p = 0.045). …”
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Evaluating the Effectiveness of Patient-Centered Standardized Prophylaxis Processes in Enhancing Patient Satisfaction and Return Intentions by Wen Tao, Tingfang Liu

“…Conducted in a first-tier city in China from 9 June to 26 July 2023, the cross-sectional survey included 826 patients from 38 dental clinics. Among the respondents, 438 received standardized prophylaxis services, while 388 were in the non-standardized group, with a mean age of 38.2 ± 12.1 years and 50.24% male participation. …”
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Can nebulised heparin reduce acute lung injury in patients with SARS‑CoV‑2 requiring advanced respiratory support in Ireland: the CHARTER‑Ireland phase Ib/IIa, randomised, parallel... by David Cosgrave, Bairbre McNicholas, Ciara Hanley, John Robert Sheehan, Padraig Calpin, Maeve Kernan, Darragh Murphy, Alberto Alvarez‑Iglesias, John Ferguson, Camilla Giacomini, Christine Greene, Catriona Cody, Shane McGeary, Marion Murphy, Marianne Fitzgerald, Gerard Curley, Barry Dixon, Roger J. Smith, Claire Masterson, Daniel O’Toole, Frank van Haren, John G. Laffey

“…Fourteen patients suffered at least one serious adverse event, 9 patients the Heparin group and 5 in the control group. …”
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Identifying threshold concepts in postgraduate general practice training: a focus group, qualitative study by Katherine Hall, Anna Chae

“…Participants were asked to describe their most transformative learning experiences. …”
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Nurse Participation in Colonoscopy Observation versus the Colonoscopist Alone for Polyp and Adenoma Detection: A Meta-Analysis of Randomized, Controlled Trials by Lei Xu, Yu Zhang, Haojun Song, Weihong Wang, Sijie Zhang, Xiaoyun Ding

“…Three RCTs with a total of 1676 patients were included. The pooled data showed a significantly higher ADR in the NP group than colonoscopist alone (CA) (45.7% versus 39.3%; RR 1.16; 95% CI, 1.04–1.30). …”
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Decision-making and role preferences for receiving individual pharmacogenomic research results among participants at a Ugandan HIV research institute by Sylvia Nabukenya, Catriona Waitt, Adelline Twimukye, Brian Mushabe, Barbara Castelnuovo, Stella Zawedde-Muyanja, Richard Muhindo, David Kyaddondo, Erisa S. Mwaka

“…A convergent parallel mixed methods study was conducted, comprising a survey of 221 research participants and five deliberative focus group discussions with 30 purposively selected research participants. …”
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Telehealth group intervention for adolescents and young adults with cancer: a feasibility pilot study protocol by Sherilynn F. Chan, Joanna Patten, Nancy Lau

“…Aim 1 is to determine the feasibility and acceptability of the intervention for all patients who participate in groups in their clinical care. …”
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Cohort retention in a pandemic response study: lessons from the SARS-CoV2 Immunity & Reinfection Evaluation (SIREN) study by Anna Howells, Katie Munro, Sarah Foulkes, Atiya Kamal, Jack Haywood, Sophie Russell, Dominic Sparkes, Erika Aquino, Jennie Evans, Dale Weston, Susan Hopkins, Jasmin Islam, Victoria Hall

“…The insights gained from this population group are important, as a highly exposed group fulfilling an essential pandemic response and patient care function. …”
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Magnesium, Aging, and the Elderly Patient by Mladen Davidovic, Dejan Trailov, Dragoslav Milosevic, Branimir Radosavljevic, Pavle Milanovic, Snezana Djurica, Helena Loncar-Stevanovic, Radmila Stevic

“…Magnesium levels in the diuretic group (100 patients) were 0.93 ± 0.094 mmol/l, while the average levels in the control group of 56 patients were 0.89 ± 0.075 mmol/l. …”
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Correlates for the severity of suicidal risk in participants with common mental disorders with comorbid chronic medical conditions in rural primary healthcare settings in India by Johnson-Pradeep Ruben, Maria L. Ekstrand, Elsa Heylen, Krishnamachari Srinivasan

“…There are limited studies assessing factors linked to the severity of suicidal risk in patients with depression and comorbid chronic medical disorders in primary healthcare (PHC) settings. …”
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Experiences and Perspectives of Medication Information and Use Among Arabic-Speaking Migrant Women in Sweden: A Multistage Focus Group Study by Al Musawi A, Axelsson M, Eriksson T, Rämgård M

“…Data were analyzed using Braun and Clark’s six-phase reflexive thematic analysis.Results: Four multistage focus group sessions with 15 participants were conducted. …”
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