Experiences of general practitioners explaining central sensitisation to patients with persistent physical symptoms: a focus group study by Henriëtte E van der Horst, Johannes C van der Wouden, Berend Terluin, Annette H Blankenstein, Carine den Boer

“…We explored how GPs used the CS model in their consultations with patients with PPS.Design and setting A qualitative focus group study among GPs in the Netherlands.Methods We instructed 33 GPs on how to explain CS to patients with PPS. …”
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Health-related Quality of Life and hospital costs of Finnish melanoma patients participating in the second Multicenter Selective Lymphadenectomy Trial (MSLT-II) by Pia J. Heino, Jukka Pappinen, John F. Thompson, Micaela Hernberg, Tiina A. Jahkola, Mark B. Faries

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Tough choices: the experience of family members of critically ill patients participating in ECMO treatment decision-making: a descriptive qualitative study by Xiangying Yang, Yao Lin, Amao Tang, Xiaokang Zeng, Weiying Dai, Qian Zhang, Li Ning

“…The cohort included nineteen family members of critically ill ICU patients from a general hospital in China. Results Eleven family members consented to ECMO treatment, and 8 refused. 4 themes and 10 subthemes emerged: (1) tough choices: the dilemma in the emergency situation, the guilt and remorse after giving up; (2) rationalisation of decision-making: ethics and morality guide decision-making, expected efficacy influences decision making, and past experience promotes decision making; (3) decision-making methods: independent decision-making, group decision-making, decision making based on patient preferences; (4) influencing factors of decision making: information and communication, social support. …”
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Improving influenza vaccine uptake in clinical risk groups: patient, provider and commissioner perspectives on the acceptability and feasibility of expanding delivery pathways in E... by Sandra Mounier-Jack, Rajeka Lazarus, Ben Kasstan, Ifra Ali

“…Healthcare providers in non-primary care settings rarely discussed or recommended influenza vaccination across patient pathways, despite being able to address the concerns raised by participants in clinical risk groups. …”
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Acceptability of donor funding for clinical trials in the UK: a qualitative empirical ethics study using focus groups to elicit the views of research patient public involvement gro... by Simon Bowman, Heather Draper, Alexander Masters, Dominic Nutt, Kirstie Shearman

“…Data were analysed using inductive thematic approach informed by the study aims and ethical analysis.Participants 22 participants were recruited: 8 research patient public involvement group members, 7 REC chairs and 7 clinical researchers. …”
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The Impact of Mild Stroke on Participation in Physical Fitness Activities by Mary Hildebrand, Megan Brewer, Timothy Wolf

“…We found a significant decrease in numbers of high-demand leisure activities in all participants and in each demographic group after mild stroke. …”
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Knowledge and understanding of information after taking decision to participate or not in a randomized trial of surgery vs radiotherapy among patients with locally advanced prostat... by Yvonne Brandberg, Olof Akre, Mia Bergenmar

“…Patients were categorized in ‘Non-participants’ or ‘Participants’. …”
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The Strength of a Story: Partnering With a Community Organization to Destigmatize Substance Use Disorder by Noah Sorkow, Cameron Lauf, Stephen H. Berns

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Identification of strengths and weaknesses of the healthcare system for persons living with rare diseases in Catalonia (Spain), and recommendations to improve its comprehensive att... by José Hernández-Rodríguez, Fernando Martínez-Valle, Xènia Acebes, Carmen Alerany, Jordi Antón, Gonzalo Calvo, Marian Corral, Jordi Cruz, M. Antònia Mangues-Bafalluy, José Mateo, Josefa Rivera, Albert Salazar, Roser Francisco, Cristina Mallol, Rita Reig-Viader, Ariadna Tigri-Santiña, Assumpta Ricart, Francesc Palau

“…Methods A task force of 13 participants with multidisciplinary expertise on RDs completed a questionnaire and participated in two focus groups. …”
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Patient safety culture through the lenses of surgical patients: a qualitative study by Magnhild Vikan, Arvid S. Haugen, Berit T. Valeberg, Ann K. Bjørnnes, Vigdis K. S. Husby, Ellen CT. Deilkås, Stein O. Danielsen

“…We purposefully recruited former surgical patients from Norwegian user organizations based on group characteristics sampling. …”
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Experiences and Perceptions on Community Client-Led ART Delivery (CCLADS) Model of Antiretroviral (ART) Delivery: Patients’ and Providers’ Perspectives in South Western Uganda. by Kasande, Meble, Tusimiirwe, Happiness, Taremwa, Michael, Lamulatu, Kabiite, Amanyire, Mark, Nakidde, Gladys, Kabami, Jane

“…Experiences also included enough time, learning some activities, and good adherence. Conclusion: Participation in the CCLADS groups provides several benefits to the patient including reduced transport, longer refills, and good adherence. …”
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Enhancement of Executive Functions but Not Memory by Multidomain Group Cognitive Training in Patients with Parkinson’s Disease and Mild Cognitive Impairment: A Multicenter Randomiz... by Elke Kalbe, Ann-Kristin Folkerts, Anja Ophey, Carsten Eggers, Saskia Elben, Karina Dimenshteyn, Patricia Sulzer, Claudia Schulte, Nele Schmidt, Christian Schlenstedt, Daniela Berg, Karsten Witt, Lars Wojtecki, Inga Liepelt-Scarfone

“…To determine CT effects in PD patients with mild cognitive impairment (PD-MCI) on cognitive and noncognitive outcomes compared to an active control group (CG) and to analyze CT success predictors. …”
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Protocol of a parallel group Randomized Control Trial (RCT) for Mobile-assisted Medication Adherence Support (Ma-MAS) intervention among Tuberculosis patients. by Zekariyas Sahile, Lua Perimal-Lewis, Paul Arbon, Anthony John Maeder

“…A total of 186 participants (93 per group) will be individually randomized into one of the two groups with a 1:1 allocation ratio by a computer-generated algorithm. …”
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Efficacy and safety of edoxaban in patients with chronic thromboembolic pulmonary hypertension: protocol for a multicentre, randomised, warfarin-controlled, parallel group trial -... by Keiichi Fukuda, Satoshi Yasuda, Hiroyuki Tsutsui, Toyoaki Murohara, Kohtaro Abe, Koichiro Tatsumi, Junji Kishimoto, Yu Taniguchi, Yuichi Tamura, Koji Todaka, Shun Minatsuki, Kazuya Hosokawa, Yuko Kobayakawa, Takumi Inami, Nobutaka Ikeda

“…The present trial seeks to evaluate whether edoxaban is non-inferior to warfarin in preventing worsening of CTEPH.Methods and analysis The KABUKI trial (is an investigator-initiated, multicentre, phase 3, randomised, single-blind, parallel-group, warfarin-controlled, non-inferiority trial to evaluate the efficacy and safety of edoxaban versus warfarin (vitamin K Antagonist) in subjects with chronic thromBoembolic pUlmonary hypertension taking warfarin (vitamin K antagonIst) at baseline) is designed to prove the non-inferiority of edoxaban to warfarin in terms of efficacy and safety in patients with CTEPH.Ethics and dissemination This study is approved by the Institutional Review Board of each participating institution. …”
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Exploring barriers and facilitators of primary care physicians towards optimising statin therapy in patients with hyperlipidaemia in the very high-risk group: a qualitative study i... by Chun Yen Beh, Rose Wai-Yee Fok, Lay Hoon Goh

“…Objectives To explore the perspectives of primary care physicians with regard to the barriers and facilitators towards optimising statin therapy in patients with hyperlipidaemia in the very high-risk group.Design Qualitative descriptive study.Setting Four polyclinics in a public primary care institution in Singapore.Participants Seven men and five women working as primary care physicians were recruited for in-depth interviews.Results The major barriers to statin optimisation identified were patients’ lack of knowledge and awareness, patients’ fear of side effects, negative external influences on patients, poor doctor–patient relationship, time constraint during consultations, physicians’ unfamiliarity with guidelines, low health literacy among the local population and lack of strong national policy. …”
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Reporting and representation of participant race and ethnicity in phase III clinical trials for solid tumors by Tianyi Wang, Dinorah J Villanueva, Ambily Banerjee, Dina Gifkins

“…Hispanic/Latino constituted 6.4% of participants. The proportion of non-White groups increased from 19.4% in trials started before 2011 to 26.2% after 2015. …”
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An open-label, randomized, post-authorization study of mirabegron in Chinese participants with overactive bladder by Zhipeng Zhang, Deyi Luo, Zhong Chen, Peng Zhang, Ganping Zhong, Keji Xie, Zhuoqun Xu, Xudong Li, Jianye Wang, Yingfan Yang, Farid Abdul Hadi, Arianne Schild

“…Secondary efficacy endpoints were the change in mean number of micturitions at weeks 4 and 8 in the mirabegron 50 mg/day group and weeks 4, 8, and 12 in the mirabegron 25 mg/day group, change from baseline to weeks 4, 8, and 12 in Grade 3 or 4 urgency episodes on the Patient Perception of Intensity of Urgency Scale, episodes of daytime incontinence, nighttime incontinence, and urgency incontinence, and Overactive Bladder Symptom Score for mirabegron 50 mg/day and 25 mg/day groups. …”
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Patients’ acceptability and implementation outcomes of a case management approach to encourage participation in colorectal cancer screening for people with schizophrenia: a qualita... by Tempei Miyaji, Yosuke Uchitomi, Hiroyuki Okada, Masatoshi Inagaki, Maiko Fujimori, Taichi Shimazu, Masaki Fujiwara, Masafumi Kodama, Ryuhei So, Takanori Matsushita, Yusaku Yoshimura, Shigeo Horii, Hirokazu Takahashi, Naoki Nakaya, Shiro Hinotsu, Keita Harada, Norihito Yamada, Yuto Yamada, Tsuyoshi Etoh

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Benefits of a Juvenile Arthritis Support Program (JASP-1) for children recently diagnosed with Juvenile Idiopathic Arthritis and their parents by Karina Mördrup, Johanna Granhagen Jungner, Eva Broström, Karin Palmblad, Cecilia Bartholdson

“…Moreover, the aim was to explore patients´ and parents´ experiences with JASP-1 and its potential impact on patients´ physical health. …”
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Incidence Of Helicobacter Pylori Infection in Association With ABO Blood Groups by Amina Zehra, Maimoona Sabir, Sumaira Sarwar, Afsheen Ishfaq, Kishmain Ahmad, Afshan Saleem

“… Objective: The study aimed to investigate the association between ABO blood groups and helicobacter infection. Method: 150 participants, including 93 females and 57 males between the age group of 18-60 years, were involved in the study. …”
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