THERAPEUTIC GENE EDITING FOR HEMOGLOBINOPATHIES by Ugo Testa, Giuseppe Leone, Maria Domenica Cappellini

“… In the last ten years, a consistent number of clinical studies have evaluated different gene approaches for the treatment of patients with sickle cell disease (SCD) and transfusion-dependent b-thalassemia (TDT). …”
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How do serum cytokine levels change in myocarditis and inflammatory dilated cardiomyopathy relative to healthy individuals? A protocol for a systematic review and meta-analysis by Romuald Wojnicz, Piotr Lewandowski, Maciej Baron, Marcin A Rojek, Marcin Goławski, Karol Krystek, Magdalena Żegleń, Pascal Zytkiewicz, Jakub Kancerek, Klaudia Gabriela Lis, Jakub Warecki, Jakub Kufel, Kamila Kuśpiel

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Timosin alpha-1 immunomodulating properties by M. V. Mayevskaya

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Chinese Herbal Medicine Combined with Intravitreal Antivascular Growth Factor Agents in Treatment of Macular Edema Secondary to Retinal Vein Occlusion: A Systematic Review and Meta... by Su Xiaojuan, Li Xiaodong, Fu Zhongmei, Ye Hejiang

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Pharmacovigilance imbalance analysis of VEGFR-TKI-related taste and smell disorders by Zhong-hua Fu, Chenglong Zhao, Yaqin Wang, Lei Zhang, Lei Wang

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Acupuncture combined with multiple therapies for angina pectoris: a systematic review and network meta-analysis by Xiangyu Kong, You Gu, Zhao Qiu

“…A random-effects Bayesian NMA was performed using R (version 4.3.1) and Stata (version 16.0).Results46 RCTs were enrolled, with 3976 patients with angina pectoris. In reducing the number of angina episodes, acupuncture [MD: −3.79; 95% CrI (−6.34, −1.31)] and acupuncture + TCM [MD: −3.06; 95% CrI (−5.49, −0.62)] were superior to antianginal therapies, with acupuncture having the best efficacy (SUCRA: 78.2%). …”
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Global, regional, and national burden of young COPD, 1990–2021, with forecasts to 2050: a systematic analysis for the global burden of disease study 2021 by Yi Zhu, Tao Shen, Ruixin Guo, Ke Liu, Xiyu Cao, Xiuli Yang, Chuantao Zhang

“…The leading DALYs attributable to risk factors for young COPD are household air pollution from solid fuels (20.4%), ambient particulate matter pollution (17.9%), and smoking (13.5%). Conclusions The global burden of ASPR, ASIR, ASDR, and age-standardised DALYs rates in young COPD has decreased, however, the absolute number of patients has increased. …”
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Environmental surveillance of SARS-CoV-2 for outbreak detection in hospital: A single centre prospective study by Hania Siddiqui, Alexandra M.A. Hicks, Aaron Hinz, Prachi Ray, Jennie Johnstone, Derek R. MacFadden, Jason A. Moggridge, Michael Fralick

“…Number of patients with COVID-19, confirmed and suspected COVID-19 outbreaks, and acute transfers to another hospital were recorded over the study duration. …”
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Hypoglycemic natural products with in vivo activities and their mechanisms: a review by Wenyi Ma, Longgao Xiao, Haiyang Liu, Xiaojiang Hao

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Resultados a corto y largo plazo tras trasplante cardíaco en pacientes con cardiopatías congénitas by Marta Molina, Elena Roselló, Manel Tauron, Juan F. Tabilo, Constanza Fernandez, Carla Gotsens, Exzequiel Pueblas, José Montiel, Sandra Casellas, Angela Irabien, Laura Corominas, Laura López, Sonia Mirabet, Antonino Ginel

“…The number of transplanted patients with congenital heart disease has increased; 59.5% of such patients was transplanted in the last 10 years. …”
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Neonatal Surgery Intensive Care Unit: Hacettepe University Experience by Umit Ayse Tandircioglu, Hasan Tolga Celik, Sule Yigit, Murat Yurdakok

“…Thereupon, premature babies with other diseases were hospitalized for an average of 9.6 days; however, those patients who require surgery were hospitalized for 33.0 days (p<0.05). …”
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Endophthalmitis following Intravitreal Injection, Cataract Surgery, and Vitrectomy: Clinical Features and Visual Outcomes by Ana Maria Cunha, Maria Manuel Iglésias, Amândio Rocha-Sousa, Fernando Falcão-Reis, Manuel Falcão

“…Endophthalmitis post-PPV had a worse visual outcome (88.9% of patients with VA worse than or equal to CF 95% CI 51.3 to 100.0%) than endophthalmitis following cataract surgery (25.9% of patients with VA worse than or equal to CF 95% CI 11.0 to 39.9%) and the IVI subgroup (44.0% of VA worse than or equal to CF 95% CI 24.0 to 67.0%) (p=0.001 and p=0.047). …”
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Relationship between Schlemm’s canal incision length and the results of ab interno gonioscopy-assisted transluminal suture trabeculotomy by Hirotaka Tanabe, Shunsuke Nakakura, Kazuaki Nishimura, Etsuko Terao, Yasuko Fujisawa, Yuki Nagata, Satomi Oogi, Miku Adachi, Kanae Matsuya

“…GATST with and without cataract surgery was performed on 87 (phakia) [77.0%] and 26 eyes (pseudophakia) [23.0%], respectively; 102 [90.3%] eyes had primary open-angle glaucoma, and 11 [9.7%] had pseudoexfoliation glaucoma. Intraocular pressure (IOP) significantly decreased at 3/6/12 months, and the antiglaucoma eyedrop number significantly decreased at 6/12 months (all P values < 0.001). …”
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Association between Hyperreflective Foci on Spectral-Domain Optical Coherence Tomography and Early Recurrence of Diabetic Macular Edema after Intravitreal Dexamethasone Implantatio... by Kyung Tae Kim, Dong Yoon Kim, Ju Byung Chae

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Hydrocortisone for Preventing Adverse Drug Reactions to Snake Antivenom: A Meta-Analysis by Jihua Feng, Zimeng Wu, Qiao Yu, Hongyuan Li, Pan Ji, Yanli Yang, Xiaoliang Zeng, Xiaowen Zheng, Chunling Zhao, Jianfeng Zhang

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Longitudinal Screening for Diabetic Retinopathy in a Nationwide Screening Program: Comparing Deep Learning and Human Graders by Jirawut Limwattanayingyong, Variya Nganthavee, Kasem Seresirikachorn, Tassapol Singalavanija, Ngamphol Soonthornworasiri, Varis Ruamviboonsuk, Chetan Rao, Rajiv Raman, Andrzej Grzybowski, Mike Schaekermann, Lily H. Peng, Dale R. Webster, Christopher Semturs, Jonathan Krause, Rory Sayres, Fred Hersch, Richa Tiwari, Yun Liu, Paisan Ruamviboonsuk

“…Results. There were 5,738 patients (12.3% STDR) in the first screening. DL and HG captured different numbers of STDR cases, and after simulated referral and excluding ungradable cases, 4,148 and 4,263 patients remained in the second screening, respectively. …”
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Charlson comorbidity index has no incremental value for mortality risk prediction in nursing home residents with COVID-19 disease by Anum Zahra, Maarten van Smeden, Petra J. M. Elders, Jan Festen, Jacobijn Gussekloo, Karlijn J. Joling, Anouk van Loon, Kim Luijken, René J. F. Melis, Simon P. Mooijaart, Karel G. M. Moons, Geeske Peeters, Harmke A. Polinder-Bos, Fenne Wouters, Anne de Hond

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Informasi Dini Terhadap Penyakit Kanker Payudara berbasis Telepon Pintar by Hesti Lina Wiraswati, Savira Ekawardhani, Sarasati Windria, Arina Al Khaq, Fauzia Nurfitri, Dini Wahyuni, Nadya Rachmawati, Rusdi Toriq Baasin, Annissa Retno Arimdayu, Annisa Retno Arimdayu

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Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples by Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Vladimir Lyadov, Vladimir Lyadov, Vladimir Lyadov, Maria Suntsova, Marat Garipov, Anna Semenova, Natalia Popova, Egor Guguchkin, Rustam Heydarov, Marianna Zolotovskaia, Xiaowen Zhao, Qing Yan, Ye Wang, Evgeny Karpulevich, Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin

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Is global health truly global? A hashtag analysis of #GlobalHealth disparities on X by Zara Arshad, Pranav Sharma, Shweta Sharma, Mustafa Sajjad Cheema, Mustafa Sajjad Cheema, Charu Agarwal, Charu Agarwal, Tamara Tango, Tamara Tango, Farhan Bin Matin, Atanas G. Atanasov, Atanas G. Atanasov, Atanas G. Atanasov, Bodrun Naher Siddiquea, Maima Matin, Olga Adamska, Artur Stolarczyk, Rahul Kashyap, Rahul Kashyap, Faisal A. Nawaz, Faisal A. Nawaz

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