Robotic-assisted surgery and kinematic alignment in total knee arthroplasty (RASKAL study): a protocol of a national registry-nested, multicentre, 2×2 factorial randomised trial as... by Ian A Harris, Samuel J MacDessi, Aziz Bhimani, Darren B Chen, Ian Harris, Michelle Lorimer, David Parker, Tamara Hooper, Richard Boyle, Jonathan Mulford, Daniel Franks, Gregory C Wernecke, Durga Bastiras, Emma Heath, Anthony Leong, Brett Fristch, David Penn, George Kirsh, John Limbers, Julian Yu, Maurice Guzman, Peter McEwen

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Case report: The case of T-cell acute lymphoblastic leukemia treated with chemotherapy followed by anti-CD7 CAR-T cells using retroviral vector by Huanhuan Zhou, Wenxiang Zhu, Qihong Ma, Ning Liu, Mengdi Jin, Yaru Feng, Lijun Zhao, Rui Sun, Rongyou Li, Huaxiu Li, Yuanyuan Shi, Jianxun Wang, Liqiong Liu, Zhi Guo, Zhi Guo, Zhi Guo

“…The CAR-T product was a novel anti-CD7 CAR-T based on retroviral vectors (RV). After infusion, the patient achieved CR within 1 month after anti-CD7 CAR-T infusion and the remission has been ongoing for 9 months to date. …”
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Class 3 Obesity in a Multidisciplinary Metabolic Weight Management Program: The Effect of Preexisting Type 2 Diabetes on 6-Month Weight Loss by David M. Medveczky, Raymond Kodsi, Kathryn Skelsey, Kathy Grudzinskas, Flavia Bueno, Vincent Ho, Nic Kormas, Milan K. Piya

“…There was no difference in percentage weight loss in those with or without T2DM (4.2±4.9% vs. 3.6±4.7%, p=0.35). Additionally, T2DM patients benefited from a 0.47% reduction in HbA1c (p<0.01) and a reduction in the number of medications from baseline to 6 months (1.8±1.0/patient vs. 1.0±1.2/patient, p<0.001). …”
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Protocol of the Nurses’ Mental Health Study (NMHS): a nationwide hospital multicentre prospective cohort study by Jiaxin Yang, Chongmei Huang, Shuiyuan Xiao, Xuting Li, Meng Ning, Zengyu Chen, Yusheng Tian, Qiang Yu, Yamin Chen, Ya-Min Li

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Efficacy and safety of an algorithm using C-reactive protein to guide antibiotic therapy applied through a digital clinical decision support system: a study protocol for a randomis... by Vandack Nobre, Pedro R Povoa, Vitoria Moura Leite Rabelo Rezende, Isabela Nascimento Borges, Cecilia Gomez Ravetti, Renan Pedra De Souza, Paula Frizera Vassalo, Ana Clara de Paula Caldas, Felipe Rodrigues Gatto, Getulio Hideyoshi Okamura, Raquel Lopes de Brito Lacerda

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Oral Midazolam Premedication for Children Undergoing General Anaesthesia for Dental Care by Saad A. Sheta, Maha AlSarheed

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Long-term sublingual bacterial immunotherapy prevents ear, nose and throat infections: A real-life study by Paula F Aarestrup, Matheus F Aarestrup, Beatriz JV Aarestrup, Edir P Cheloni, Fernando M Aarestrup

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The Kidney Transplant Evaluation Process in the Elderly: Reasons for Being Turned down and Opportunities to Improve Cost-Effectiveness in a Single Center by Beatrice P. Concepcion, Rachel C. Forbes, Aihua Bian, Heidi M. Schaefer

“…Variables were collected to identify reasons for patients being turned down and to determine the number of unnecessary tests performed. …”
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EXPERIENCE OF USING TELEMEDICINE TOOLS TO PROVIDE MEDICAL CARE IN THE TERRITORY OF DONETSK REGION DURING MARTIAL LAW IN UKRAINE by Oleksandr Heiko, Taras Gutor

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Comparative efficacy and safety of intra-articular analgesics after knee arthroscopy: a Bayesian network meta-analysis protocol by Yilun Wang, Hongyi He, Yuchen He, Dong-Xing Xie, Xiaoxiao Li

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Opioid use and opioid overdose in the Netherlands – a 10 years retrospective study of naloxone administration in Dutch emergency departments by Bram Kok, Joris Holkenborg, Alba van der Have, Brigitte van de Kerkhof – van Bon, Joris Datema, Pieter Veenstra, Djoke Douma-den Hamer, Cornelis Kramers

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A retrospective study of pembrolizumab combined with XELOX regimen in the treatment of advanced gastric cancer by FENG Huizhi, LIU Jingmei, BU Xiaoqian

“…This study was approved by the ethics committee of Shanxi Province Cancer Hospital (ethics number: KY2023081). Results: After treatment, the proportion of progressive disease (PD) in the observation group was 20.0% (9/45), which was lower than that in the control group (40.0%, 18/45). …”
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Hereditary neuropathy with liability to pressure palsies: a case series report by S. Naudžiūnaitė, R. Bunevičiūtė, B. Burnytė

“…Three patients (42.9%) reported that symptoms were caused by direct mechanical compression of the nerve. …”
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Profile of Skin Disorders in Unreached Hilly Areas of North India by Deepak Dimri, Venkatashiva Reddy B, Amit Kumar Singh

“…Of the total patients 16.9% were affected by dermatitis and 16.7% by acne. …”
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Consumption of folk medicine in men-seeking treatment for infertility by Abdulaziz Baazeem, Thamer Mishal M. Alqurashi, Yasser Homaidi H. Alharbi, Raad Abdullah D. Aldahhas, Mutaz Hassan A. Fatani

“…About 55.3% of the patients were 40 years old or less. Patients who consumed some form of alternative medicine are 38.9%. …”
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Inappropriate medication prescribing, polypharmacy, potential drug-drug interactions and medication regimen complexity in older adults attending three referral hospitals in Asmara,... by Nuru Abdu, Saleh Idrisnur, Hanae Said, Lude Kifle, Natnael Habte, Semira Ghirmai, Tomas Tewelde, Senai Mihreteab Siele, Eyasu H. Tesfamariam

“…The number of drugs prescribed was a determinant of MRCI score (r = 0.625, p < 0.001). …”
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Instagram's impact on dental consumers: analyzing toothpaste hashtags by Khalifa S. Al-Khalifa, Rasha AlSheikh, Basmah O. Alakloby, Hind M. Alharbi, Razan F. Alghamdi, Saqib Ali, Laila Al Dehailan

“…The contents of each post, including the number of likes, number of followers, content type, poster role, post content, post theme, post type, and account type were collected. …”
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Protocol of a randomised controlled phase II clinical trial investigating PREoperative endoscopic injection of BOTulinum toxin into the sphincter of Oddi to reduce postoperative pa... by Phillip Knebel, Thilo Hackert, Markus W Büchler, Thomas Bruckner, Peter Sauer, Markus K Diener, Christine Tjaden, Ulla Klaiber, Pascal Probst, Eike Martin, Steffen Luntz

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Epidemiology, Disease Severity and Outcome of Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza Viruses Coinfection Seen at Egypt Integrated Acute Respiratory Infection... by Manal Fahim, Wael H. Roshdy, Ola Deghedy, Reham Kamel, Amel Naguib, Shymaa Showky, Nancy Elguindy, Mohammad Abdel Fattah, Salma Afifi, Amira Mohsen, Amr Kandeel, Khaled Abdelghaffar

“…Cocirculation of influenza (Flu) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (SARS-CoV-2/Flu) represent a public health concern as it may worsen the severity and increase fatality from coronavirus disease 2019. An increase in the number of patients with coinfection was recently reported. …”
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The Impact of COVID-19 on Hospitalised COPD Exacerbations in Malta by Yvette Farrugia, Bernard Paul Spiteri Meilak, Neil Grech, Rachelle Asciak, Liberato Camilleri, Stephen Montefort, Christopher Zammit

“…There was no significant difference in patient demographics or medical comorbidities. In 2020, there was a significantly lower number of patients with AECOPD who received nebulised medications during admission (60.4% in 2020 vs. 84.9% in 2019; p≤0.001). …”
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