Evaluation of Chest CT Scan as a Screening and Diagnostic Tool in Trauma Patients with Coronavirus Disease 2019 (COVID-19): A Cross-Sectional Study by Hossein Abdolrahimzadeh Fard, Salahaddin Mahmudi-Azer, Sepideh Sefidbakht, Pooya Iranpour, Shahram Bolandparvaz, Hamid Reza Abbasi, Shahram Paydar, Golnar Sabetian, Mohamad Mahdi Mahmoudi, Masoume Zare, Leila Shayan, Maryam Salimi

Get full text

Examining the therapeutic potential and side effects of calcium channel blockers in mortality and morbidity of patients with stroke: A systematic review of pre-clinical and clinica... by Sevak Hatamian, Asad Abdi, Fatemeh Sadat Seyedi Asl, Armin Tafazolimoghadam, Arian Tavasol, Seyed Ali Mousavi Nejad, Reza Madadi, Zohre Tajabadi, Mina Dehghani, Najmeh Ahmadpoor, Mobina Fathi, Mohammadreza Hajiesmaeili, Navid Nooraei

Get full text

Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by Graham McIlroy, Charlotte Gaskell, Aimee Jackson, Emily Yafai, Rachel Tasker, Catherine Thomas, Sonia Fox, Rebecca Boucher, Fitsum Ghebretinsea, Claire Harrison, Adam J. Mead, Mary Frances McMullin

Get full text

Comparison of Nasal Colonization of Methicillin-Resistant Staphylococcus aureus in HIV-Infected and Non-HIV Patients Attending the National Public Health Laboratory of Central Nepa... by Kalash Neupane, Binod Rayamajhee, Jyoti Acharya, Nisha Rijal, Dipendra Shrestha, Binod G C, Mahesh Raj Pant, Pradeep Kumar Shah

“…Among the HIV-infected, patients of age group 31–40 years were the ones with highest carriage rate 36 (45%), while in non-HIV patients, the highest rate 13 (28.9%) of carriage was detected among the patients of age group 21–30 years. …”
Get full text

Oxygenation targets for endovascular therapy in acute ischemic stroke patients (Oxy-TARGET): protocol for a single-centre, open-label randomised controlled trial by Anxin Wang, Zhengfang Hu, Ruquan Han, Fa Liang, Youxuan Wu, Minyu Jian, Xinyan Wang, Yunzhen Wang, Haiyang Liu, Xuan Hou, Kangda Zhang, Zihui Zhang

Get full text

Delayed PCI 12 Hours after the Onset of Symptoms Is Associated with Improved Outcomes for Patients with ST-Segment Elevation Myocardial Infarction: A Real-World Study by Wen-Juan Xiu, Hai-Tao Yang, Ying-Ying Zheng, Yi-Tong Ma, Xiang Xie

“…The number of all-cause deaths in the delayed PCI group and that in the MT group were 55 (9.3%) and 138 (28.9%), respectively, and a significant difference between the groups was indicated for this variable (P<0.001). …”
Get full text

Impact of pharmacist-led intervention for reducing drug-related problems and improving quality of life among chronic kidney disease patients: A randomized controlled trial. by Roheena Zafar, Inayat Ur Rehman, Yasar Shah, Long Chiau Ming, Khang Wen Goh, Amal K Suleiman, Tahir Mehmood Khan

“…This study was aimed to evaluate the impact of clinical pharmacist-led interventions on the mean number of DRPs and the mean QoL score difference per patient DRPs in CKD patients.…”
Get full text

Study protocol for an observational study of cerebrospinal fluid pressure in patients with degenerative cervical myelopathy undergoing surgical deCOMPression of the spinal CORD: th... by Armin Curt, Carl Moritz Zipser, Nikolai Pfender, Jose Miguel Spirig, Michael Betz, Jose Aguirre, Markus Hupp, Mazda Farshad, Martin Schubert

Get full text

SERS Platform Based on Bimetallic Au-Ag Nanowires-Decorated Filter Paper for Rapid Detection of miR-196ain Lung Cancer Patients Serum by Ji Xia, Yifan Liu, Menglin Ran, Dan Lu, Xiaowei Cao, Youwei Wang

Get full text

Randomised cross-over trial of vildagliptin and pioglitazone as add-on therapy in patients with type 2 diabetes: predicting Which One is Right Here (WORTH) study protocol by Yannan Jiang, Tony R Merriman, Rui Qian Yeu, Rebecca Brandon, Dale Griffiths, Kate Smallman, Allan Moffitt, Glenn Doherty, Ryan Paul, Jennie Harré Hindmarsh, Kerry Macaskill-Smith, Brandon Orr-Walker, Rinki Murphy

Get full text

Correlation between Glycated Hemoglobin Levels and Knowledge, Attitude, and Practice of Type 2 Diabetic Patients Attending Primary Health Care Centers in Dubai Health Authority by Hind Al Razooqi, Bashayer AlNajjar, Ebrahim AlShamsi, Kaltham Ibrahim, Wadeia Sharief, Hamda Khansaheb, Marwan Zidan

“…Knowledge, attitude, and practice (KAP) significantly impact the outcome of self-management in patients with diabetes, yet the association between KAP of type 2 diabetes and the combined control of the glycated hemoglobin (HbA1c) level to date remains uncertain due to lack in the number of studies. …”
Get full text

Anti-vascular Endothelial Growth Factor Outpatient Treatment Patterns in Patients with Exudative Age-related Macular Degeneration from a Japanese Hospital Claims Database by Tomohiro Iida, Aya Narimatsu, Kenji Adachi, Edward CY Wang

Get full text

Robot-Assisted versus Laparoscopic-Assisted Gastrectomy among Gastric Cancer Patients: A Retrospective Short-Term Analysis from a Single Institution in China by Li-Fei Sun, Kai Liu, Xue-Shang Su, Xuan Wei, Xiao-Long Chen, Wei-Han Zhang, Xin-Zu Chen, Kun Yang, Zong-Guang Zhou, Jian-Kun Hu

“…RAG was safe and feasible for gastric cancer patients, with superiority in the dissection of No. 9 lymph nodes.…”
Get full text

Neurocognitive impact of different irradiation modalities for patients with grade I-II skull base meningioma: a prospective multi-arm cohort study (CANCER COG) by Paul Lesueur, Florence Joly, Benedicte Clarisse, Justine Lequesne, Dinu Stefan, Jacques Balosso, Marie Lange, Sebastien Thureau, Aurelie Capel, Marie Castera, Berenice Legrand, Nicolas Goliot, Jean Michel Grellard, Thomas Tessonier, Helene Castel, Samuel Valable

Get full text

Discontinuation of immune checkpoint inhibitors for reasons other than disease progression and the impact on relapse and survival of advanced melanoma patients. A systematic review... by Konstantinos Lallas, Eftychia Chatziioannou, Derya Durak, Georg Frey, Lina Maria Serna-Higuita, Marie-Lena Rasch, Athanassios Kyrgidis, Eleni Timotheadou, Zoe Apalla, Ulrike Leiter, Lukas Flatz, Lukas Flatz, Aimilios Lallas, Teresa Amaral, Teresa Amaral

“…Random-effects models were preferred, and subgroup and sensitivity analyses were conducted to investigate possible sources of heterogeneity.Results38 and 35 studies were included in qualitative and quantitative synthesis, respectively. From 2542 patients discontinued treatment with ICIs electively or due to TLTs, 495 experienced progression [number of studies (n)=34, RR 20.9%, 95%CI 17.1 – 24.7%, I2 85%) and higher rates were detected in patients with TLTs compared to elective discontinuation. …”
Get full text

TIGIT inhibitor M6223 as monotherapy or in combination with bintrafusp alfa in patients with advanced solid tumors: a first-in-human, phase 1, dose-escalation trial by Wei Gao, Ping Hu, Aung Naing, Meredith McKean, Anthony Tolcher, Lillian L Siu, Keyvan Tadjalli-Mehr, Anja Victor, Emilia Richter, Marco A F Nogueira Filho, Thomas Kitzing, Stephan Gleicher, Daniel Holland

“…Further evaluation of M6223 is ongoing in combination with the PD-L1 inhibitor avelumab in patients with advanced urothelial carcinoma (JAVELIN Bladder Medley; NCT05327530).Trial registration number NCT04457778.…”
Get full text

Daily versus three-times-weekly azithromycin in Chinese patients with non-cystic fibrosis bronchiectasis: protocol for a prospective, open-label and randomised controlled trial by Jing Li, Fei Chen, Wei Xiao, Feng Li, Lan Chen, Ting He, Yanxiong Mao, Aiping Zou, Bo Fan, Weihao Ni, Huimin You, Wenjiang Fu

Get full text

Efficacy and safety of rivaroxaban in preventing venous thromboembolism in postoperative patients with gynecological malignancies: protocol for a randomised controlled open-label t... by Hong Zhou, Fei He, Ting Wei, Shuyi Wu, Jinhua Zhang, Huan Yi

Get full text

A multidisciplinary collaborative care model involving family members in the treatment of type 2 diabetes mellitus and associated diabetes distress in young and middle-aged patient... by Wang Yan-Ping, Peng Lu-Yao, Yuan Xian-Ming, Chen Ting-Ting, Li Lin, Deng Kai-Qin

Get full text

A novel intraoperative Esophagus-Sparing Anastomotic Narrowing Revision (ESANR) technique for patients who underwent esophagojejunostomy: three case reports and a review of the lit... by Jian Zhou, Zhenhong Wang, Guobiao Chen, Yi Li, Min Cai, Fathima Shifly Pannikkodan, Xiangzhi Qin, Dan Bai, Zhenbing Lv, Lei Gong, Yunhong Tian

Get full text