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Reflecting on the impact of the COVID pandemic on patient management and its subsequent influence on long-term outcomes: a case–control study in the field of esophago-gastric cance...
Published 2025-01-01“…Results A consistent demographic profile across these periods was maintained, but with a significant decrease in patient referrals during P1 (35.25% reduction from PP to P1 and 9.5% reduction from PP to P2), quicker ‘time to treatment’ during P1 (130.8 days in P1 vs 162 in PP and 178.9 in P2), and notable changes in treatment modalities. …”
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TERTp Mutation and its Prognostic Value in Glioma Patients Under the 2021 WHO Classification: A Real‐World Study
Published 2025-01-01“…Samples were analyzed for TERTp mutation and 59 other gene alterations and chromosome copy number variations. Results A total of 207 patients were included. …”
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Clinico-epidemiological characteristics of patients reported with intra-hospital infection in the Pediatric Intensive Care Unit. Cienfuegos, 2015-2019
Published 2022-02-01“…Four patients died.<br /><strong>Conclusions:</strong> the nosocomial infection rate is comparable with the numbers reported internationally. …”
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Cost–Benefit Analysis of in vivo Reflectance Confocal Microscopy for Melanoma Diagnosis in a Real-World Clinical Setting
Published 2025-01-01“…Studi Analisi Valutazioni Economiche S.r.l., Health Economics & Outcomes Research, Milan, Italy; 3Azienda Unità Sanitaria Locale – IRCCS di Reggio Emilia, Skin Cancer Center, Reggio Emilia, Italy; 4Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy; 5Skin Cancer Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy; 6Department of Medicine and Surgery, University of Parma, Parma, Italy; 7Dermatology Unit, Department of Surgical, Medical, Dental & Morphological Sciences with Interest Transplant, Oncological & Regenerative Medicine, University of Modena and Reggio Emilia, Modena, 41125, Italy; 8Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy; 9Porphyria and Rare Diseases Unit, San Gallicano Dermatological Institute-IRCCS, Roma, Italy; 10Department of Drug Sciences, CEFAT-Center of Pharmaceuticals Economics and Medical Technologies Evaluation, University of Pavia, Pavia, Italy; 11Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Dermatology Clinic, Sapienza University of Rome, Rome, Italy*These authors contributed equally to this workCorrespondence: Giacomo Matteo Bruno, Department of Drug Sciences, University of Pavia, Pavia, Italy, Email giacomomatteo.bruno@unipv.itBackground: In a recent prospective, multicenter, two-arm randomized controlled trial (RCT), we demonstrated that adjunctive reflectance confocal microscopy (RCM) in routine clinical practice provides clinical benefits, including safe melanoma detection and a 43.3% reduction in the number needed to excise (NNE).Methods: A cost–benefit analysis was conducted based on NNEs for standard care (5.3) and adjunctive RCM (3.0). …”
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Examining patient distress and unmet need for support across UK renal units with varying models of psychosocial care delivery: a cross-sectional survey study
Published 2020-09-01“…The questionnaire was completed by 509 patients, resulting in an overall response rate of 67.7%.Outcome measures The prevalence of distress and patient-reported need for support.Results The results showed that 48.9% (95% CI 44.5 to 53.4) of respondents experienced distress. …”
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Genomic analysis of the SMN1 gene region in patients with clinically diagnosed spinal muscular atrophy: a retrospective observational study
Published 2025-02-01“…Furthermore, for 1 patient with a homozygous SMN1 missense mutation, SMA was not suspected by the current copy number screening method. …”
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Adherence and influencing factors of high-flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease: A meta-analysis
Published 2025-01-01“…Meta-analysis results showed a COPD patient HFNC adherence rate of 32.7%. Negative factors included the number of acute exacerbations (odds ratio [OR] =2.17), adverse reactions (OR = 4.13), regular follow-up (OR = 9.45), educational level (OR = 5.38), and concurrent medications (OR = 4.71). …”
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Risk factors for lymphatic leakage following radical cystectomy and pelvic lymph node dissection in patients with muscle-invasive bladder cancer
Published 2025-01-01“…On multivariate analysis, higher number of dissected lymph nodes (OR 3.278, 95% CI 1.135–9.471, p = 0.028) was found to be a independent risk factor for lymphatic leakage. …”
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Prevalence and Risk Factors of Medication Errors in Enteral Tube Feeding Among ICU Patients: A Comprehensive Cross-Sectional Analysis
Published 2024-04-01“…These errors were influenced by factors such as the number of drugs received by the patient, the hospital, and specific shifts. …”
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Budget Impact Analysis of Treatment Flow Optimization in Epilepsy Patients: Estimating Potential Impacts with Increased Referral Rate to Specialized Care
Published 2021-06-01“…**Results:** In the current treatment flow, the number of refractory patients treated with four drugs by non-specialized care were estimated as 8766 and yielded JPY5.8 billion annually. …”
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Comparison of Efficacy and Safety of Lispro and Aspart Evaluated by Continuous Glucose Monitoring System in Patients with Newly Diagnosed Type 2 Diabetes
Published 2018-01-01“…This is a single-blind randomized controlled trial. A total of 110 patients with newly diagnosed T2DM and with hemoglobin A1c (HbA1c%) above 9% was hospitalized and randomly divided into two groups: group Asp (NovoRapid group) and group Lis (Prandilin group). …”
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