Global prevalence of platelet-type von Willebrand disease by Omid Seidizadeh, Andrea Cairo, Maha Othman, Flora Peyvandi

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Refining prognostic assessment of diffuse large B-cell lymphoma: insights from multi-omics and single-cell analysis unveil SRM as a key target for regulating immunotherapy by Xiaojie Liang, Jia Guo, Baiwei Luo, Weixiang Lu, Qiumin Chen, Yeling Deng, Yunong Yang, Liang Wang

“…Genomic analysis revealed extensive copy-number loss in the chemokine and interleukin coding regions within HPSI. …”
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Effectiveness of Intravitreal Ranibizumab in Nonvitrectomized and Vitrectomized Eyes with Diabetic Macular Edema: A Two-Year Retrospective Analysis by Ozgun Melike Gedar Totuk, Ayse Yagmur Kanra, Mohammed Nadim Bromand, Guler Kilic Tezanlayan, Sevil Ari Yaylalı, Irem Turkmen, Aylin Ardagil Akcakaya

“…The medical records of 28 eyes (11 vitrectomized and 17 nonvitrectomized) of 28 patients (mean age, 59.0 ± 9.6 years; male to female ratio 1 : 1) who were diagnosed with DME and had received IVR treatment were reviewed retrospectively. …”
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Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled... by Eva Skovlund, Rune Haaverstad, Henrik Zetterberg, Jorunn L Helbostad, Rolf Busund, Johan Raeder, Theis Tønnessen, Torgeir Bruun Wyller, Melanie R Simpson, Nils Kristian Skjærvold, Bjørn Erik Neerland, Svein Aslak Landsverk, Ieva Martinaityte, Hilde Margrethe Norum, Geir Selbaek, Elisabeth Skaar, Arjen JC Slooter, Øyvind Sverre Svendsen, Alexander Wahba

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The Effect of Postoperative Tranexamic Acid and Dexamethasone on Quality of Recovery After Arthroscopic Rotator Cuff Repair: a Double-Blinded, Randomized Controlled Trial by Jiang X, Xu C, Yuan C, Gao W, Liu W, Wang Y, Wang H, Yu W, He Y

“…This study aimed to determine whether the combined application of TXA and DEX could improve postoperative recovery during the first 24 hours in ARCR patients. Our goal is to relieve the acute postoperative pain and promote fast recovery and rapid discharge for ARCR patients.Patients and Methods: Ninety-six patients who underwent ARCR from December 2023 to March 2024 were enrolled in this double-blinded, randomized control trial (Registration number, ChiCTR2300078507). …”
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The diagnostic performance of indocyanine green for the sentinel node biopsy in prostate cancer: A systematic review and meta-analysis by Siyang Ma, Jianxuan Sun, Jinzhou Xu, Ye An, Mengyao Xu, Chenqian Liu, Sihan Zhang, Lintao Miao, Xingyu Zhong, Na Zeng, Haodong He, Shaogang Wang, Qidong Xia

“…The protocol has been registered in the International Prospective Register of Systematic Reviews database, and the register number is CRD42023421911. Four bibliographic databases were searched, i.e., PubMed, EMBASE, Cochrane Library, and Web of Science, to retrieve articles studying the diagnostic performance of ICG for the SNB in PCa from the inception to Sep 9, 2023. …”
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Rationale and design of the HOVON 170 DLBCL-ANTICIPATE trial: preventing anthracycline-induced cardiac dysfunction with dexrazoxane by Marijke Linschoten, Jesse Geels, Erik van Werkhoven, Heleen Visser-Wisselaar, Martine E. D. Chamuleau, Arco J. Teske, Lourens Robbers, Simone Oerlemans, Heleen Crommelin, Marleen Breems-de Ridder, Astrid Schut, Folkert W. Asselbergs, Anna van Rhenen, on behalf of the HOVON 170 DLBCL – ANTICIPATE consortium

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High-dose dual therapy for Helicobacter pylori eradication inducing less impact on the gut microbiota by Jia-Lun Guan, Ting-Ting Xu, Ya Lin, Yan-Shuai Mo, Bi-Yu He, Ying-Ying Han, Ji-Yan Li, Su-Hong Xia, Ya-Ni Zhou, Jia-Zhi Liao, Pei-Yuan Li

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Utility of 5-ALA for resection of CNS tumours other than high-grade gliomas: a protocol for a systematic review by Michael D Jenkinson, Ashwin Venkatesh, Colin Watts, Michael T C Poon, Victoria Wykes, Stephen John Price, Puneet Plaha, Georgios Solomou, Melissa Gough, Conor S Gillespie, Aref-Ali Gharooni, Waqqas Patel

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Exploring the clinical profiles and management of juvenile dermatomyositis in Africa: a survey of African rheumatology care providers by Jessica Perfetto, Laura B. Lewandowski, Dawn M. Wahezi, Vanessa Ogega, Joan Ahimbisibwe, Kate Webb, Christiaan Scott, Angela Migowa

“…Topics included respondent specialty, number of JDM patients followed, severe manifestations, and available diagnostic tools and medications (with and without considering cost). …”
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How Much Do We Know about the Biopsychosocial Predictors of Glycaemic Control? Age and Clinical Factors Predict Glycaemic Control, but Psychological Factors Do Not by Mohammad Farris Iman Leong Bin Abdullah, Hatta Sidi, Arun Ravindran, Paula Junggar Gosse, Emily Samantha Kaunismaa, Roslyn Laurie Mainland, Norlaila Mustafa, Nurul Hazwani Hatta, Puteri Arnawati, Amelia Yasmin Zulkifli, Luke Sy-Cherng Woon

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A Multicenter, Prospective Study of a New Fully Covered Expandable Metal Biliary Stent for the Palliative Treatment of Malignant Bile Duct Obstruction by Bret T. Petersen, Michel Kahaleh, Richard A. Kozarek, David Loren, Kapil Gupta, Thomas Kowalski, Martin Freeman, Yang K. Chen, Malcolm S. Branch, Steven Edmundowicz, Michael Gluck, Kenneth Binmoeller, Todd H. Baron, Raj J. Shah, Timothy Kinney, William Ross, Paul Jowell, David Carr-Locke

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Genome-Wide Profiling of Human Papillomavirus DNA Integration into Human Genome and Its Influence on PD-L1 Expression in Chinese Uygur Cervical Cancer Women by Feng Yang-chun, Wang Sen-yu, Zhang Yuan, Huang Yan-chun

“…Logistic regression analysis showed that 9p24.1 existing integration sites and the number of all gene integration were risk factors for PD-L1 expression (odds ratio 17.313 and 1.012; 95% confidence interval 1.691-177.213 and 1.001-1.023). …”
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TMBocelot: an omnibus statistical control model optimizing the TMB thresholds with systematic measurement errors by Xin Lai, Shaoliang Wang, Xuanping Zhang, Xiaoyan Zhu, Yuqian Liu, Zhili Chang, Zhili Chang, Xiaonan Wang, Xiaonan Wang, Yang Shao, Yang Shao, Jiayin Wang, Yixuan Wang

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Diagnostic accuracy of CCTA-derived versus angiography-derived quantitative flow ratio (CAREER) study: a prospective study protocol by Liang Zhang, Yang Chen, Cheng Li, Ming Li, Shaofeng Guan, Xinkai Qu, Tingwen Weng, Qian Gan, Zehang Li, Wenzheng Han, Xinrong Zhai, Lin Qi, Xifeng Chang, Shengxian Tu

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ANGPTL3 overcomes sorafenib resistance via suppression of SNAI1 and CPT1A in liver cancer by Yang-Hsiang Lin, Cheng-Yi Chen, Hsiang-Cheng Chi, Meng-Han Wu, Ming-Wei Lai, Chau-Ting Yeh

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Long-Term Results of Medical and Surgical Methods for Elimination of the Internal Anal Sphincter Spasm in Chronic Anal Fissure (NCT03855046) by S. I. Achkasov, R. Yu. Khryukin, E. E. Zharkov, A. A. Ponomarenko, O. Yu. Fomenko, N. I. Klopkov, Z. Z. Kamaeva, E. Yu. Lebedeva, K. I. Sagidova

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How far back do we need to look to capture diagnoses in electronic health records? A retrospective observational study of hospital electronic health record data by Tom Marshall, Elizabeth Sapey, Miles D Witham, Steve Harris, Rachel Cooper, Chris Plummer, Felicity Evison, James Wason, Heather J Cordell, Suzy Gallier, Fiona E Matthews, Ewan Pearson, Avan A Sayer, Mervyn Singer, Joanne Field, Mohammed Osman, Sian Robinson, Victoria Bartle, Thomas Scharf, Jadene Lewis, Rominique Doal, Peta le Roux, Ray Holding, Paolo Missier

“…For each diagnosis, we derived the number of patients with the diagnosis recorded at least once over the full 10-year lookback period, and then compared this with shorter lookback periods from 1 year to 9 years prior to the index admission.Results Seven of the top 10 most common diagnoses in the COPD dataset reached >90% completeness by 6 years of lookback. …”
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Acceptance commitment therapy (ACT) for psychological distress associated with inflammatory bowel disease (IBD): protocol for a feasibility trial of the ACTforIBD programme by Richard Gearry, Matthew Fuller-Tyszkiewicz, Andrew McCombie, Peter Gibson, Simon Knowles, Lisa Olive, Antonina Mikocka-Walus, Subhadra Evans, Leanne Raven, Daniel Romano, Eric O, Madeleine Dober, Leesa van Niekerk, Susan Chesterman

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Feasibility study of a randomised controlled trial of preoperative and postoperative nutritional supplementation in major lung surgery by Amelia Swift, Sebastian T Lugg, Babu Naidu, Nikolaos Efstathiou, Amy Kerr, Hazem Fallouh, Maninder Kalkat, Richard Steyn, Salma Kadiri, Ehab Bishay, Krishna Kholia, Venessa Rogers

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