Pragmatic algorithm for visual assessment of 4-Repeat tauopathies in [18F]PI-2620 PET Scans by Theresa Bauer, Matthias Brendel, Mirlind Zaganjori, Alexander M. Bernhardt, Alexander Jäck, Sophia Stöcklein, Maximilian Scheifele, Johannes Levin, Thilo van Eimeren, Alexander Drzezga, Osama Sabri, Henryk Barthel, Robert Perneczky, Günter Höglinger, Nicolai Franzmeier, Johannes Gnörich

“…Methods: A total of 83 individuals with [18F]PI-2620 PET scans were included. Participants were classified as probable 4R-tauopathies (n = 29), Alzheimer's disease (AD) (n = 20), α-synucleinopathies (n = 15), and healthy controls (n = 19) based on clinical criteria. …”
Get full text

Supervised vs. Self-Managed Exercise Therapy for Improving Shoulder Function After Traumatic Dislocation and Sprain: A Systematic Review and Meta-Analysis by Daniel Koska, Robert Zetzsche, Tobias A. Mayer, Christian Maiwald

“…Five studies with a total 689 participants were included (conservative: <i>n</i> = 538 across two studies; post-surgical: <i>n</i> = 151 across three studies). …”
Get full text

Lack of Male-Female Differences in Disposition and Esterase Hydrolysis of Ramipril to Ramiprilat in Healthy Volunteers after a Single Oral Dose by Tom B. Vree, Erik Dammers, Ivan Ulc, Stefan Horkovics-Kovats, Miroslav Ryska, IJsbrand Merkx

“…Plasma concentration and area under the concentration-time curve until the last measured concentration (AUCt) data of ramipril and its active metabolite ramiprilat (-diacid) were obtained from a randomised, cross-over bioequivalence study in 36 subjects (18 females and 18 males). Participants received a single 5-mg oral dose of two different formulations of ramipril (Formulation I and II). …”
Get full text

Feasibility study of Omaha System in the construction of health education program for elderly patients with chronic obstructive pulmonary disease (奥马哈系统在老年慢性阻塞性肺疾病健康教育方案构建中的可行性研究)... by YANG Yuanqin (杨元琴), YIN Cuihong (尹翠红), SHEN Xiaohong (申晓红), WU Sichao (吴思超), WANG Anxiu (王安秀)

“…Conclusion The Omaha system articles can describe most of the clinical health problems in elderly COPD patients, and the relevant knowledge and skills of these health problems are particularly important for the disease management of elderly COPD patients. …”
Get full text

Attention speed and anterior cingulate cortex volume in female and male veterans with suicide ideation and attempts by Erin C. McGlade, Erin C. McGlade, Erin C. McGlade, James R. Yancey, James R. Yancey, James R. Yancey, Keenan E. Roberts, Keenan E. Roberts, Keenan E. Roberts, Audrey Elias, Audrey Elias, Chelsea Carson, Chelsea Carson, Chelsea Carson, Jiyoung Ma, Jiyoung Ma, Margaret R. Legarreta, Margaret R. Legarreta, Deborah A. Yurgelun-Todd, Deborah A. Yurgelun-Todd, Deborah A. Yurgelun-Todd

“…A subset of Veterans also completed a structural magnetic resonance imaging protocol. Participants were grouped on history of suicidal ideation (SI), suicide attempt (SA), and no SB (HC).ResultsAnalyses from the Ruff 2 &amp; 7 test showed that Veterans with a history of SA performed more slowly on Automatic Detection Speed (ADS) and Controlled Search Speed (CSS) compared to Veterans with SI and no SB. …”
Get full text

Impact of subgingival periodontal treatment on systemic markers of inflammation in patients with metabolic syndrome: a systematic review of randomized clinical trials by Marie Chavez, Asshly Ramirez, Akram Hernández-Vásquez, Daniel Comandé, Diego Azañedo

“…A qualitative synthesis of the evidence was performed.ResultsTwo RCTs with 228 participants (ages 35–65) were included. Montero et al. reported significant reductions in CRP levels favoring the treatment group at 3 months (2.7 mg/L ± SE: 0.4 vs. 3.9 mg/L ± SE: 0.6; p = 0.001) and 6 months (2.9 mg/L ± SE: 0.4 vs. 4.0 mg/L ± SE: 0.8; p = 0.004). …”
Get full text

Rationale and design of a multicentre randomised controlled trial on circulating tumour DNA-guided neoadjuvant treatment strategy for locally advanced rectal cancer (CINTS-R) by Bin Wu, Yi Xiao, Xiao Zhang, Tao Xu, Qian Liu, Wei Fu, Yang An, Yongheng Li, Guole Lin, Huadan Xue, Guoju Wu, Jiaolin Zhou, Hongwei Yao, Zhenjun Wang, Weijie Chen, Junyang Lu, Guannan Zhang, Xiaoyuan Qiu

“…The secondary endpoints include time to recurrence, 2-year overall survival, 2-year disease-free survival, clinical complete response (cCR) rate, near cCR rate and pathologically complete response rate, pathological tumour regression grade and quality of life.Ethics and dissemination This protocol has been approved by the ethics committee of Peking Union Medical College Hospital, with approval number I-23PJ157, and by the institutional review boards of all the participating centres. All data will be collected and stored in a specially designed database. …”
Get full text

Smoking cessation is a protective factor for lung cancer onset and mortality: a population-based prospective cohort study by Wei Yin, Zhuochen Lin, Wei-Jie Gong, Wen-Xuan Wang, Ying-Ying Zhu, Yi-Lin Fu, Han Yang, Jin-Xin Zhang, Peng Lin, Ji-Bin Li

“…Generalized linear regression models were used for AAO of LC outcomes and Cox models for mortality outcomes. Results Participants over 60 years old could still benefit from smoking cessation to prolong AAOs (β = 1.613 for men, P = 0.003; β = 1.533 for women, P = 0.018). …”
Get full text

Hospital in-reach family-centred social prescribing pilot for children with neurodisability: mixed methods evaluation with social return on investment analysis by Laura Gordon, Megan Hastry, Angela Bate, Katie Gordon, Emily Greaves, Simoni Dimitriadou, Tim Rapley, Anna Purna Basu

“…We recruited children aged < 16y with neurodisability, identified during inpatient stays, their parents/carers and siblings. Participants received link worker support for 6 months, extending beyond hospital discharge. …”
Get full text

Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized control... by Chenhui Wang, Mengwei Yan, Yuru Li, Lei Han, Hongqian Wang, Shufeng Jia, Xingchen Liu, Yang Liu, Fan Wu, Baoguo Wang

“…Our study aims to assess the therapeutic potential of hydrogen-oxygen mixture (H2-O2) inhalation for KOA.MethodsIn this randomized controlled trial, eligible elderly KOA patients were randomly assigned to either Group H or Group C. Both groups participated in a 12-week home-based exercise (HBE) program, which included knee-joint exercises and health education. …”
Get full text

READMISSIONS TO ADOLESCENT PSYCHIATRIC INPATIENT CARE: A REGISTER STUDY by VISA VADÉN, RIITTAKERTTU KALTIALA, TIMO HOLTTINEN

“…To explore independent associations of the partially overlapping explaining variables, we used multivariable analyses. …”
Get full text

Comparison of anterior versus posterior approach for the treatment of cervical compressive myelopathy due to ossification of the posterior longitudinal ligament by Amr A. A Gaber, Mohamad Alaa El-Din Habib, Mohamed AR AbdelFatah, Mostafa K. Ghobashy

“…This systematic review and meta-analysis (MA) covered 12 research articles including 1070 participants. Results Showed no statistically significant variations among the anterior group and posterior group regarding preoperative modified Japanese Orthopedic Association Score (mJOA score) (P = 0.23, SMD = 0.9; heterogeneity: P = 0.85; I 2 = 18%). …”
Get full text

Developing a comprehensive inventory to define harm reduction housing by Sofia Zaragoza, Joseph Silcox, Sabrina Rapisarda, Charlie Summers, Patricia Case, Clara To, Avik Chatterjee, Alexander Y. Walley, Miriam Komaromy, Traci C Green

“…The initial 44-item inventory of services, policies and site best practices was further refined with expert and participant feedback and application, then finalized to generate a 32-item inventory. …”
Get full text

L-shaped association of dietary inflammatory index (DII) and chronic diarrhea: results from NHANES 2005–2010 by Qing Zhao, Yue Xu, Xiangrui Li, Xiaotian Chen

“…Stratified by sex, the analysis revealed a notable rise in the risk of chronic diarrhea with increasing DII among female participants (all P for trend < 0.05). This tendency remained constant even after full adjustment (P for trend = 0.0192), whereas no significant association was noted in males (all P for trend > 0.05). …”
Get full text

Characteristics of the Approximate-Optimal Training Indicators of Goalkeepers in Modern Football by Igor Doroshenko, Andrii Svatyev, Valerij Shamardin, Bogdan Khorkavyy, Daria Vaniuk, Eduard Doroshenko

“…Analysis of the competitive activity of qualified goalkeepers allows us to state that the average goalkeeper in modern football – a participant in the latest world and European championships, UEFA tournaments has the following anthropometric parameters: height – 195 ± 2 cm; weight – 90 ± 2 kg; weight-height index – 0.45 ± 0.01 c.u. …”
Get full text

Combination of mentor-based and resident-based learning may benefit to improving the ability of clinical practice in resident training by Min Li, Tao Liu, Yiqiong Wen, Min Zhang, Wenye Zhu, Xuming Wang, Yunjiao Hou, Lin Li, Anju Zu, Shibo Sun

“…Methods Seventy-two residents who participated in standardized resident training (SRT) were recruited and randomly divided into the CMRL and MBL groups. …”
Get full text

New Onset of Diabetes Mellitus and Associated Factors among COVID-19 Patients in COVID-19 Care Centers, Addis Ababa, Ethiopia 2022 by Asaminew Habtamu Sane, Migbar Sibhat Mekonnen, Melsew Getnet Tsegaw, Wuletaw Chane Zewde, Edmialem Getahun Mesfin, Hailu Asmare Beyene, Taye Mezgebu Ashine, Kasie Gebeyehu Tiruneh, Melkie Ambaw Mengistie

“…The mean age of the study participants was 53.2 years with (SD=13.35). The study findings showed that 31.1% (CI: 25.4-37.4) of COVID-19 patients had new onset of diabetes mellitus; of those, 11.8% had type 1 and 88.2% had type 2 diabetes. …”
Get full text

Association between dietary patterns and chronic kidney disease in elderly patients with type 2 diabetes: a community-based cross-sectional study by Ling Cao, Peng Yu, Lei Zhang, Qiuming Yao, Fang Zhou, Xiaoying Li, Xiaomu Li

“…Dietary intake was assessed using a validated food frequency questionnaire, and dietary patterns were identified using factor analysis. Each participant was assigned a score for each identified dietary pattern, with higher scores indicating a greater alignment of their diet with the respective pattern. …”
Get full text

Écriture en langue africaine et communication sociale au Sénégal : le cas de la publicité urbaine dakaroise en wolof by Oneil BOUPENGA -MOUMOSSY

“…L’intégration de la langue wolof en tant qu’outil d’unité nationale permet de développer une communication sociale efficace qui participe au développement de l’écriture en wolof, renforçant bien évidemment son statut de langue majoritaire. …”
Get full text

Penerapan Algoritma Support Vector Machine pada Analisis Sentimen Terhadap Identitas Kependudukan Digital by Rita Ajeng Lestari, Adhitia Erfina, Wisuda Jatmiko

“…The government has committed to supporting efforts to digitize E-KTP into Identitas Kependudukan Digital which the public must participate in supporting this digitization effort. …”
Get full text