Characteristics and publication status of minimally invasive glaucoma surgery trials registered in ClinicalTrials.gov, 2007–2024: a cross-sectional study by Chuzhi Peng, Hongyan Jia, Jianping Hu, Yonghong Jiao

“…The majority of MIGS trials were not overseen by a Data Monitoring Committee (DMC) (71.4%) and enrolled fewer than 200 participants (85.2%). MIGS trials targeting Schlemm’s canal (SC) (60.2%) were significantly more prevalent than those targeting subconjunctival space (24.6%) and suprachoroidal/supraciliary space (15.3%). …”
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Mental health in public safety personnel with workplace injuries requiring surgery: a longitudinal population-wide administrative data study in Manitoba, Canada by Tracie O Afifi, Jitender Sareen, Dan Chateau, Alyson Mahar, Jordan Nantais, James Bolton, Allen Kraut, Sarvesh Logsetty, Thomas Turgeon, Brenda Comaskey, Justin Gawaziuk, Rae Spiwak, Lauren Burton, Anthony Wightman, Jai Sareen, Natalie Mota

“…The objective of this study was to investigate whether PSP with traumatic physical workplace injuries requiring surgery with anaesthetic have higher post-injury rates of mental disorders compared with the general population with similar non-workplace injuries.Design Retrospective longitudinal cohort study.Setting Population-based study using linked anonymised administrative data for PSP and the general population in Manitoba, Canada.Participants This study compared two groups hospitalised for a traumatic physical injury requiring surgery with anaesthetic between 1 January 2002 and 31 December 2018: (1) PSP (n=293) injured in the workplace and matched 1:5 on sex, age, geographical region and surgical procedure code with (2) individuals in the general population (GenPop) injured outside the workplace (no Workers Compensation Board claim) (n=1198).Primary and secondary outcomes and measures As planned in the study protocol, the prevalence of mental disorders including anxiety, depression and substance use was measured in the cohorts 2 years pre- and post-injury.Results This study found an elevated unadjusted risk of depression in PSP compared with the general population in the 2 years post-injury, adjusting for pre-injury mental health (rate ratio, 1.49; 95% CI, 1.02 to 2.17; p<0.0001). …”
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Role Of Low Dose Aspirin In Preventing Preterm Birth In Patients With Previous History Of Preterm Delivery by Maliha Sadaf, Aasia Saleem, Tallat Farkhanda, Khansa Iqbal, Sabeen Ashraf, Amna Iftikhar

“…Results: The age of participants included in the study was 18 to 40 years. …”
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Strategies adopted by men to deal with uncertainty and anxiety when following an active surveillance/monitoring protocol for localised prostate cancer and implications for care: a... by Chris Metcalfe, Jenny Donovan, Julia Wade, Vincent J Gnanapragasam, Michael Davis, David Neal, Richard Martin, Athene Lane, Edward Rowe, Freddie Hamdy, James Catto, Emma Turner, David Gillatt, Eleanor Walsh, Derek Rosario, Tim Peters, Roger Kockelbergh, Alan Paul, Peter Holding, Howard Kynaston, Owen Hughes, Prasad Bollina, Alan Doherty, Edgar Paez

“…This study investigated men’s strategies for coping with the uncertainties of active monitoring (AM, a surveillance strategy within the Prostate testing for cancer and Treatment, ProtecT trial) over the longer term and implications for optimising supportive care.Design Longitudinal serial in-depth qualitative interviews every 2–3 years for a median 7 (range 6–14) years following diagnosis.Setting Four centres within the UK Protect trial.Participants Purposive sample of 20 men with localised PCa: median age at diagnosis 64 years (range 52–68); 15 (75%) had low-risk PCa; 12 randomly allocated to, 8 choosing AM. …”
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Association of oxidative balance score with the risk of all-cause and CVD mortality in younger US adults with diabetes by Chang Liu, Guoan Xiang, Dan Liang, Xuanbo Zhao, Kun Xiao, Lixin Xie

“…This study enrolled 3501 participants. The endpoints were all-cause and CVD mortality, determined by the National Death Index (NDI). …”
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Beverage consumption modifies the risk of type 2 diabetes associated with ambient air pollution exposure by Chaonan Fan, Wenjuan Wang, Wenxue Xiong, Zhiyao Li, Li Ling

“…Annual average concentrations of fine particulate matter (PM2.5 and PM10) and nitrogen oxides (NO2 and NOX) were estimated to represent the long-term AP exposure using the land use regression model. …”
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The relation of traumatic childhood experiences with psychological symptoms and self-esteem in physical education and sport students by Azize Atlı Ozbas, Mehmet Kocak, Nermin Gurhan

“…A hundred and five students who agreed participating in the study and filled in the data collection forms fully were recruited the study. …”
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Relationship between oxidative balance indicators and Chronic Kidney Disease. by Xinyun Chen, Fangyu Shi, Wenhui Yu, Chang Gao, Shenju Gou, Ping Fu

“…A total of 18,951 participants were included after applying specific inclusion criteria. …”
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Deciphering the potential ability of DExD/H-box helicase 60 (DDX60) on the proliferation, diagnostic and prognostic biomarker in pancreatic cancer: a research based on silico, RNA-... by Dongdong Zhang, Enze Zhang, Ying Cai, Yixin sun, Peiji Zeng, Xiaohua Jiang, Yifan Lian

“…Conclusion In summary, DDX60 can be used as a novel biomarker related to the diagnosis and treatment of pancreatic cancer, participate in tumor proliferation, and is associated with poor prognosis in patients.…”
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Chlamydia cases in women of reproductive age, 2006–2020: an analysis of surveillance data from Southern China by Peizhen Zhao, Peng Liang, Jinshen Wang, Wenqian Xu, Shujie Huang, Cheng Wang

“…The reported rate among women of reproductive age correlated with the net migration rate (RR = 1.2; 95% CI: 1.2–1.3) and the ratio of those participating in child-bearing insurance to the permanent population (RR = 1.5; 95% CI: 1.4–1.6). …”
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Blockade of IL-17A/IL-17R Pathway Protected Mice from Sepsis-Associated Encephalopathy by Inhibition of Microglia Activation by Bo Ye, Tianzhu Tao, Andong Zhao, Liyuan Wen, Xiaofei He, Yi Liu, Qiang Fu, Weidong Mi, Jingsheng Lou

“…In conclusion, blockade of the IL-17A/IL-17R pathway inhibited microglia activation and neuroinflammation, thereby partially reversing sepsis-induced cognitive impairment. …”
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Magnitude, patterns, and factors associated with liver disease among clinically suspected clients in Eastern Ethiopia: hidden public health tragedy by Aliya Nuri, Sufian Jeilu, Yared Teklu, Kadir Abdu, Ahmed Muhye, Milkiyas Solomon Getachew, Imam Dagne, Muluken Yigezu, Sewmehon Amsalu Adugna, Vanisha S. Nambiar, Abdu Oumer

“…Results A total of 388 (92%) adults were included and liver disease was diagnosed among 295 (76%; 71.5–80.2) of the study participants, where chronic liver disease due to non-viral (65.1%) and viral causes (34.9%) were prevalent. …”
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Variability and performance of NHS England’s ‘reason to reside’ criteria in predicting hospital discharge in acute hospitals in England: a retrospective, observational cohort study... by Elizabeth Sapey, Simon Ball, David McNulty, Felicity Evison, Suzy Gallier, Katherine Reeves

“…We aimed to understand the degree of intercentre and intracentre variation in R2R-related metrics reported to NHSE, define an SDM implemented within a single centre Electronic Health Record to generate an electronic R2R (eR2R) and evaluate its performance in predicting subsequent discharge.Design Retrospective observational cohort study using routinely collected health data.Setting 122 NHS Trusts in England for national reporting and an acute hospital in England for local reporting.Participants 6 602 706 patient-days were analysed using 3-month national data and 1 039 592 patient-days, using 3-year single centre data.Main outcome measures Variability in R2R-related metrics reported to NHSE. …”
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Time to Relapse and Relapse Predictors in Patients with Schizophrenia at Ayder Comprehensive Specialized Hospital, Northern Ethiopia by Habtamu Endashaw Hareru, Kebede Embaye Gezae, Daniel Sisay W/tsadik, Gebremedhin Berhe Gebregergs

“…The survival experiences of participants were compiled using a life table. Both univariate and multivariate Cox regression models were used for variable selection. …”
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Factors influencing health-related quality of life in children with asthma: insights from Addis Ababa public hospitals by Tsehaynew Kasse, Selemaye Zenebe, Yalemzer Agegnehu, Arega Abebe Lonsako

“…Logistic regression was employed to identify factors influencing health-related quality of life Statistical significance was set at p < 0.05 with a 95% confidence interval.ResultsThe study found that 46% [95% CI: 37.6–54.4%] of the study participants had a poor quality of life. Factors associated with an increased likelihood of poor quality of life included caregivers’ lack of formal education (Adjusted Odds Ratio [AOR]: 1.39 [1.80–10.69]), a family history of asthma (AOR: 2.51 [1.46–4.299]), longer asthma duration (AOR: 3.47 [1.89–6.39]), uncontrolled asthma (AOR: 3.47 [1.89–6.39]), moderate persistent asthma (AOR: 2.4 [1.40–4.20]), and comorbidities (AOR: 2.4 [1.40–4.20]).ConclusionThe study highlights almost half of asthmatic children had a poor quality of life in Addis Ababa. …”
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Effectiveness and safety of metformin in 51 675 patients with type 2 diabetes and different levels of renal function: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Soffia Gudbjörnsdottir, Ann-Marie Svensson, Björn Eliasson, Linus Schioler, Björn Zethelius, Nils Ekström, Jan Cederholm, Junmei Miao Jonasson

“…Objective To evaluate the effectiveness and safety of metformin use in clinical practice in a large sample of pharmacologically treated patients with type 2 diabetes and different levels of renal function.Design Observational study between July 2004 and December 2010, mean follow-up 3.9 years.Setting Hospital outpatient clinics and primary care in Sweden.Participants 51 675 men and women with type 2 diabetes, registered in the Swedish National Diabetes Register, and on continuous glucose-lowering treatment with oral hypoglycaemic agents (OHAs) or insulin.Main outcome measures Risks of cardiovascular disease (CVD), all-cause mortality and acidosis/serious infection, associated with each treatment regimens, were analysed in all patients and in subgroups with different estimated glomerular filtration rate (eGFR) intervals. …”
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ehealth literacy and health literacy among immigrants and their descendants compared with women of Danish origin: a cross-sectional study using a multidimensional approach among pr... by Claus Thorn Ekstrøm, Richard H Osborne, Sarah Fredsted Villadsen, Hajer Hadi, Israa Ismail, Lars Kayser

“…Objective To explore ehealth literacy, ability to actively engage with healthcare providers and health system navigation among pregnant immigrant women and their descendants compared with women of Danish origin.Design and setting A cross-sectional survey at antenatal clinics in 2016, Denmark.Participants Pregnant women attending antenatal care (n=405).Outcome measures The eHealth Literacy Questionnaire (eHLQ) and two domains from the Health Literacy Questionnaire (HLQ): ability to actively engage with healthcare providers and health system navigation. …”
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The Impact of the COVID-19 Surge Response on Motivation Among Anesthesiology Residents and Fellows: A discussion of findings from semi-structured interviews at Montefiore Medical C... by Sujatha Ramachandran, Kateryna Slinchenkova, Jonathan Leff, David Adams, Sarang Koushik, Omar Viswanath, Naum Shaparin

“… # Methods All residents and fellows (Focus Group 1) of the Anesthesiology Department of Montefiore Medical Center in Bronx, NY were invited to participate in a semi-structured interview via Zoom, held on two separate dates. …”
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Practice and factors associated with sunlight exposure of infants among mothers in Ethiopia: a systematic review and meta-analysis by Shambel Dessale Asmamaw, Tibebu Habte Zewde, Abiel Teshome, Esayas Nigussie

“…The quality assessment of included articles was evaluated using the Newcastle–Ottawa Scale. …”
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Antibiotic Resistance of Enteric Bacteria in HIV-Infected Patients at the Banka Ad-Lucem Hospital, West Region of Cameroon by Ornella J. T. Ngalani, Armelle T. Mbaveng, Wiliane J. T. Marbou, Roland Y. Ngai, Victor Kuete

“…CD4+ T-lymphocyte count and serum hs-CRP of HIV-positive and HIV-negative patients were examined, respectively, by flux cytometry and the ELISA solid-phase direct sandwich method. Among all the participants, 39 (26.35%) were males and 109 (73.65%) were females. …”
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