Vitamin K‐dependent gamma‐carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGF... by Zheng Wu, Qing Ye, Shan Zhang, Li‐Peng Hu, Xiao‐Qi Wang, Lin‐Li Yao, Lei Zhu, Shu‐Yu Xiao, Zong‐Hao Duan, Xue‐Li Zhang, Shu‐Heng Jiang, Zhi‐Gang Zhang, De‐Jun Liu, Dong‐Xue Li, Xiao‐Mei Yang

“…Abstract Background Vitamin K‐dependent γ‐glutamic acid carboxylation (Gla) proteins are calcium‐binding and membrane‐associated, participating in coagulation, bone turnover, and cancer biology. …”
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Exploring the association between socioeconomic inequalities in chronic respiratory disease and all-cause mortality in China: findings from the China Health and Retirement Longitud... by Zhuo Zhang, Guoshuai Shi, Faguang Jin, Yan Zhang

“…Additionally, Cox regression analysis showed that participants with CRD had an increased risk of all-cause mortality (HR = 1.49, 95% CI: 1.34, 1.65).ConclusionInequalities exists in CRDs in China, with the prevalence of these diseases primarily concentrated among economically disadvantaged groups. …”
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Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report by Norny Syafinaz Ab Rahman, Nur Alyaa Anisa Mat Harom, Nor Ilyani Mohamed Nazar

“…Case Presentations: This case report presents two cases involving patients with chronic diseases residing in a rural area of Pahang, Malaysia, who participated in pharmacist-led HMR visits. The first case describes a 62-year-old single Malay female with multiple chronic conditions, including Type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, and bronchial asthma, managed with eight prescribed medications. …”
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Bacteriological Profile of Chronic Suppurative Otitis Media and its Antibiotic Sensitivity Pattern at a Tertiary Care Hospital by Geeta Geeta, Naveen G, Apoorva P, Harish MO, Arathi Nair, Harshitha MC, Kiran Revankar, Girish PB

“…Results Mean age of participants was 33.5 years. 94.1% had the unilateral infection. 94.4% had a tubo-tymphanic type while 5.6% had attico-antral type. 70 (77.8%) samples showed mono-microbial growth, 13 (14.4%) showed poly-microbial growth and 7 (7.8%) samples showed no growth in aerobic culture. …”
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Differential attainment at national selection for higher surgical training: a retrospective cohort study by Amanda Lee, Jennifer Cleland, John Hines, Peter Brennan, Ricky Ellis, Yasin Al-Tawarah

“…The objective of this study was to characterise the relationship between candidate sociodemographic factors and performance at National Selection for HST in the UK.Design A retrospective cohort study.Setting National Selection for HST in the UK.Participants All UK graduates in the UKMED database (https://www.ukmed.ac.uk) who underwent selection for HST from 2012 to 2019.Outcomes and measures Performance at HST Selection for each surgical specialty is measured by assessment of the candidate’s academic portfolio and multiple objective structured clinical examination style stations testing knowledge and skills. …”
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Correlation between Parenting Style by Personality Traits and Mental Health of College Students by Minggui Ge, Xiaomeng Sun, Zhen Huang

“…There is no significant difference in their average scores of the partiality of father or mother between the high-anxiety group and the low-anxiety group. …”
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Profile of non-invasive physical health indicators associated with cognitive performance in Chinese older adults: evidence from the China Health and Retirement Longitudinal Study by Xiyu Wei, Chao Li, Dongyu Liu, Jieyi Chen, Yumeng Ju, Jin Liu, Bangshan Liu, Yan Zhang

“…Methods The present study utilized a three-year longitudinal cohort design, with data from the China Health and Retirement Longitudinal Study (CHARLS). 4,869 participants aged 60–97 years from CHARLS wave 2015 and 2018 who were cognitively and physically healthy were included in analysis. …”
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Approach to shoulder instability: a randomized, controlled trial by Julien Caron, MD FRCSC, Kellen Walsh, MD FRCSC, Tinghua Zhang, MSc, Rashed AlAhmed, MBChB MSc FRCSC, Peter B. MacDonald, MD FRCSC, Cristina Bassi, MD, J Whitcomb Pollock, MD FRCSC MSc, Katie McIlquham, BSc, Peter Lapner, MD FRCSC

“…Methods: This was a prospective, randomized controlled trial involving participants who were randomized to either the ISI score or CTA and were followed for 24 months postrandomization. …”
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Treatment and prescribing trends of antihypertensive drugs in 2.7 million UK primary care patients over 31 years: a population-based cohort study by Tibor Schuster, Laurent Azoulay, Julie Rouette, Emily G. McDonald, James M. Brophy

“…Objectives To describe the prescribing trends of antihypertensive drugs in primary care patients and assess the trajectory of antihypertensive drug prescriptions, from first-line to third-line, in patients with hypertension according to changes to the United Kingdom (UK) hypertension management guidelines.Design Population-based cohort study.Setting and participants We used the UK Clinical Practice Research Datalink, an electronic primary care database representative of the UK population. …”
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A comprehensive scoping review of intergenerational dance programmes for cohorts with a generational gap. by Siobhán O'Reilly, Orfhlaith Ní Bhriain, Sarah Dillon, Amanda M Clifford

“…Experiences and social outcomes were the most assessed outcomes, with a lack of studies examining physical outcomes. Participants reported enjoying the programmes stating they felt proud for taking part and looked forward to sessions. …”
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Solving unknown primary cancer with earlier diagnosis - the SUPER-ED trial: study protocol for a stepped-wedge cluster randomised controlled trial to support earlier diagnosis for... by Anna Ugalde, Richard W. Tothill, Stephen Quinn, Hui-Li Wong, Owen Prall, Catherine Mitchell, Nilmini Wickramasinghe, Clare Fedele, Natalie Richards, Elizabeth Todio, Cindy Bryant, Louisa G. Collins, Sarah McLean, Hyun Soo Ko, Tim Akhurst, Christopher Steer, Bo Gao, Mark Wong, Chloe Georgiou, Narayan Karanth, Anna Kuchel, Louise Nott, Shamsudheen Padinharakam, Mark Shackleton, Ian M. Collins, Madhu Singh, Rachel Wong, Zee Wan Wong, Alexis Butler, Tharani Sivakumaran, Penelope Schofield, Linda Mileshkin

“…Secondary outcomes are whether the type of tumour is diagnosed, clinical trial participation, referral to palliative care, patient-reported physical, social and mental health, patient-reported understanding and uncertainty. …”
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Chronic kidney disease progression in patients with previous type 2 diabetes and/or hypertension: a population-based cohort study from primary care in Spain by David Vizcaya, Betlem Salvador-González, Oriol Cunillera-Puértolas, Sílvia Cobo-Guerrero, José Romano-Sánchez, Daniel Bundó-Luque, Ariadna Arbiol-Roca

“…Objectives To evaluate whether between hypertension and type 2 diabetes (T2D)—established drivers of chronic kidney disease (CKD) progression—one might be more strongly associated with CKD progression than the other.Design Cohort study using a primary care database (electronic health records).Setting Primary care in Catalonia, Spain.Participants 438 273 patients with CKD identified from the Information System for Research in Primary Care database in Catalonia (2007–2017) and stratified into four mutually exclusive groups based on the presence/absence of hypertension and/or T2D. …”
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Psicanálise e pesquisa social de hermenêutica profunda by Thomas Leithauser

“… O ponto de partida do artigo é a crítica de Theodor W. Adorno à psicanálise. …”
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Prediction models used in the progression of chronic kidney disease: A scoping review. by David K E Lim, James H Boyd, Elizabeth Thomas, Aron Chakera, Sawitchaya Tippaya, Ashley Irish, Justin Manuel, Kim Betts, Suzanne Robinson

“…The type of information extracted included: the author(s), title of article, year of publication, study dates, study location, number of participants, study design, predicted outcomes, type of prediction model, prediction variables used, validation assessment, limitations and implications.…”
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Are We Overlooking Anatomical Contributions to Dynamic Knee Valgus? by Matt Dewald, Madison Andersen, Laura Higgins, Emma Porter, Alex Wickersham

“… # Results 50 subjects (35 included) participated in this study. With a cued DKV jump, ground contact time had a moderate positive correlation with DKV measurements (r=.49, p\<0.01), however, this was not the case with subjects' natural jump and cued no DKV alignment jumps. …”
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Trajectories of Change, Illness Understanding, and Parental Worries in Children and Adolescents Undergoing Internet-Delivered Cognitive-Behavioral Therapy for Functional Abdominal... by Eva Skovslund Nielsen, Karen Kallesøe, Tine Bennedsen Gehrt, Ellen Bjerre-Nielsen, Maria Lalouni, Lisbeth Frostholm, Marianne Bonnert, Charlotte Ulrikka Rask

“…ResultsRecruitment of participants began in June 2022 and is finalized for substudy 1 and ongoing for substudies 2 and 3. …”
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ChatGPT-4 Performance on German Continuing Medical Education—Friend or Foe (Trick or Treat)? Protocol for a Randomized Controlled Trial by Christian Burisch, Abhav Bellary, Frank Breuckmann, Jan Ehlers, Serge C Thal, Timur Sellmann, Daniel Gödde

“…ResultsAs of October 2024, the acquisition of data and students to participate in the trial is ongoing. Upon analysis of our acquired data, we predict our findings to be ready for publication as soon as early 2025. …”
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Effects of carob rich-polyphenols on oxidative stress markers and physical performance in taekwondo athletes by Nawel Gaamouri, Hassane Zouhal, Katsuhiko Suzuki, Mehrez Hammami, Aloui Ghaith, El Hafedh El Mouhab, Anthony C. Hackney, Ismail Laher, Omar Ben Ounis

“…We studied the effects of daily supplementation with carob (40 g/d, for six-weeks) on performance levels and antioxidant capacity in 22 taekwondo athletes (age 21.9 ± 1.2 years; height 1.66 ± 0.34 m; weight 68.3 ± 16.9 kg; women = 10, men = 12) using a randomized, double-blinded study. Participants were divided into an experimental group (EG) or placebo group (PG). …”
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Incidence and risk factors for mortality of vertebral osteomyelitis: a retrospective analysis using the Japanese diagnosis procedure combination database by Hideo Yasunaga, Hirotaka Chikuda, Kiyohide Fushimi, Hiromasa Horiguchi, Toru Akiyama, Kazuo Saita

“…Objective To examine the incidence of vertebral osteomyelitis (VO) and the clinical features of VO focusing on risk factors for death using a Japanese nationwide administrative database.Design Retrospective observational study.Setting Hospitals adopting the Diagnosis Procedure Combination system during 2007–2010.Participants We identified 7118 patients who were diagnosed with VO (International Classification of Diseases, 10th Revision codes: A18.0, M46.4, M46.5, M46.8, M46.9, M48.9 and M49.3, checked with the detailed diagnoses in each case and all other codes indicating the presence of a specific infection) and hospitalised between July and December, 2007–2010, using the Japanese Diagnosis Procedure Combination database.Main outcome measures The annual incidence of VO was estimated. …”
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Factors Associated with Linkage to Care following Community-Level Identification of HIV-Positive Clients in Lira District by Claire Adwar, Steven Sean Puleh, Isaac Ochaba, Isaac Ogweng, Deo Benyumiza, Kosta Amusu, Brenda Achola, Francis Ocen, Lydia Abolo, Edward Kumakech, Celestino Obua

“…Quantitative data were collected from 329 randomly selected study participants using interviewer-administered questionnaires. …”
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