Bridging the gap: understanding the perspective of healthcare professional students towards precision medicine in a Nigerian tertiary institution (a cross-sectional study) by Ezinwanne Jane Ugochukwu, Jennifer Chinwe Edom, Faith Olanrewaju Omotayo, Agatha Adaeze Amaechi, Chinedu Benneth Obetta, Chibueze Anosike, AbdulMuminu Isah, Chukwuemeka Michael Ubaka

“…Results A total of 431 healthcare professional students participated in this study. Fewer than half (n = 200, 46.4%) were pharmacy students, and the majority were within the age range of 21–25 years (n = 288, 66.8%). …”
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Noi cercetări arheologice la cetatea Saschiz I. Incinta exterioară by Marcu Istrate, D., Dobrotă, S., Rezi, B., Gál, S.

“…All newly identified wall structures were in poor condition, a situation that may be partially explained through the miserly use of mortar and the common employment of dry foundations. …”

Association of clinical knowledge with patient care ownership among resident physicians: a nationwide cross-sectional study in Japan by Hirohisa Fujikawa, Hidetaka Tamune, Yuji Nishizaki, Taro Shimizu, Yu Yamamoto, Kiyoshi Shikino, Miwa Sekine, Hiroyuki Kobayashi, Yasuharu Tokuda

“…Results We included 1836 participants in our statistical analysis. Multivariable linear regression analysis revealed that after adjustment for possible confounders, GM-ITE total scores showed a significantly negative association with PCO in the highest score quartile (adjusted mean difference − 0.20, 95% confidence interval (CI) -0.33 to -0.07, compared with the lowest score quartile). …”
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Crossing Borders, Opening Minds? VET Tandem Partnerships in a Dutch- German Cross-Border Region by Stephanie Wilde, Hugo Kremer, Jana Stelzer

“…Challenges faced by the tandem partnerships include: Maintaining continuity in the participating VET institutions and the teachers responsible for the exchanges and overcoming logistical and bureaucratic hurdles. …”
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What are the cost-savings and health benefits of improving detection and management for six high cardiovascular risk conditions in England? An economic evaluation by Katy Cooper, Alan Brennan, David Bagguley, Helen Buckley Woods, Chloe Thomas, Penny Breeze, Michael Gillett, Edward Goka, Hazel Y Squires, Gilly Brenner, Joanna Leaviss, Mark Clowes, Laura Heathcote

“…Objectives To estimate the cost savings and health benefits of improving detection of individuals at high risk of cardiovascular disease (CVD) in England, to determine to which patient subgroups these benefits arise, and to compare different strategies for subsequent management.Design An economic analysis using the School for Public Health Research CVD Prevention Model.Setting England 2018.Participants Adults aged 16 and older with one or more high cardiovascular risk conditions, including hypertension, diabetes, non-diabetic hyperglycaemia, atrial fibrillation, chronic kidney disease and high cholesterol.Interventions Detection of 100% of individuals with CVD high risk conditions compared with current levels of detection in England. …”
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Applying implementation science frameworks to understand why fisherfolk continue or discontinue pre-exposure prophylaxis for HIV prevention in Uganda: a qualitative analysis by Simon Mwima, Rhoda Kitti Wanyenze, Rose Naigino, Laura M Bogart, William Musoke, Semei C Mukama, Stella Allupo, Herbert Kadama, Barbara Mukasa

“…This study explores factors influencing PrEP continuation and discontinuation among fisherfolk in Uganda using the Consolidated Framework for Implementation Research (CFIR).Methods Participants were recruited from two fishing communities near Entebbe, Uganda. …”
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Waist circumference and altered metabolic indices are associated with increased resting pulse rate in middle-aged adults by Laith Ashour, Zaid Taimeh, Moaiad Hussein, Zeid Jarrar, Nicola Hanna Madani, Noor Mnaa, Layan Ayesh, Ahmad Odeh, Sama Samer Abu Monshar, Muath Mohammad Dabas, Rawan Almejaibal

“…The total number of participants was 1839 (weighted n=1,390,763), the mean age was 38.1 [standard deviation (SD)=2.0] and the mean pulse rate was 75.2 (SD=11.6). …”
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Risk of residual/recurrent cervical diseases in HPV-positive women post-conization depends on HPV integration status by Wenyu Lin, Yuxuan Huang, Yan Zhang, Lixiang Huang, Hongning Cai, Guanxiang Huang, Ye Li, Qiaoyu Zhang, Huifeng Xue, Binhua Dong, Pengming Sun

“…Results Among the 73 participants with HPV infection post-conization, 10 cases (13.7%) were positive for HPV integration. …”
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Effects of a novel non-pharmacological intervention based on respiratory biofeedback, neurofeedback and median nerve stimulation to treat children with ADHD by Eduardo Santamaría-Vázquez, Eduardo Santamaría-Vázquez, Eduardo Santamaría-Vázquez, Anayali Estudillo-Guerra, Lna Ali, Diana Martinez, Roberto Hornero, Roberto Hornero, Leon Morales-Quezada

“…This study aimed to: (1) investigate the effectiveness of a combined R-BFB and NFB intervention to treat ADHD, and (2) explore the potential benefits of MNS in enhancing the proposed intervention.MethodsSixty children with ADHD participated in the study, divided into two experimental groups. …”
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Inflammatory lipid biomarkers and transplant-free mortality risk in hepatitis B-related cirrhosis and hepatic encephalopathy by Ke Shi, Xiaojing Wang, Zhang Yi, Yanqiu Li, Ying Feng, Xianbo Wang

“…We aimed to assess the predictive ability of these parameters in patients with hepatitis B virus-related cirrhosis and overt hepatic encephalopathy (HBV-related OHE).DesignWe conducted an analysis of 1,404 participants diagnosed with HBV-related OHE between January 2008 and July 2023. …”
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Meta-analysis examining the association between low platelet monoamine oxidase levels and Zuckerman's sensation seeking scale in a sex dependent manner by Jordan Winfield, Ian A. Mendez, Gabriel A. Frietze

“…Fourteen studies with a total of 24 correlations and 1,470 participants were included in the analyses. Across 24 independent effect sizes, the correlations ranged from −0.74 to 0.40. …”
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Establishment and validation of a nomogram for coronary artery lesions in children with Kawasaki disease by Chong Hu, Chong Hu, Xiao Yan, Henglian Song, Qin Dong, Qin Dong, Changying Yi, Changying Yi, Jianzhi Li, Jianzhi Li, Xin Lv, Xin Lv

“…This is especially valuable in the early identification of the risk of CALs, which will lead to proper diagnosis and treatment to reduce their associated complications.MethodsRetrospective clinical data of 677 children diagnosed with KD who were treated in the Children's Hospital Affiliated with Shandong University were analyzed. All the participants were divided into the CAL group and no CAL group according to their coronary echocardiography results. …”
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Aerodynamic optimization of small diffuser Augmented Wind Turbines: A differential evolution approach by Turan Dias Oliveira, Luzia Aparecida Tofaneli, Alex Álisson Bandeira Santos

“…In order to contain the increase in the concentration of CO2 in the atmosphere and its harmful consequences, studies point to the need to increase the participation of non-fossil energy in the world energy matrix. …”
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The Role of Indoxyl Sulfate in Exacerbating Colorectal Cancer During Chronic Kidney Disease Progression: Insights into the Akt/β-Catenin/c-Myc and AhR/c-Myc Pathways in HCT-116 Col... by Yu Ichisaka, Chihiro Takei, Kazuma Naito, Manami Higa, Shozo Yano, Toshimitsu Niwa, Hidehisa Shimizu

“…The AhR antagonist CH223191 also inhibited c-Myc upregulation, indicating involvement of the AhR/c-Myc pathway. MK2206 partially attenuated the indoxyl sulfate-induced AhR transcriptional activity, suggesting that Akt activation influences the AhR/c-Myc pathway. …”
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Moscatilin inhibits vascular calcification by activating IL13RA2-dependent inhibition of STAT3 and attenuating the WNT3/β-catenin signalling pathway by Tingting Zhang, Mengmeng Zhu, Jialing Ma, Zhenghong Liu, Zhidan Zhang, Meijie Chen, Yaping Zhao, Huaxin Li, Shengnan Wang, Xiaoning Wei, Wenwen Zhang, Xiaoxiao Yang, Peter J. Little, Danielle Kamato, Hao Hu, Yajun Duan, Baotong Zhang, Jianbo Xiao, Suowen Xu, Yuanli Chen

“…We further validated the participation of Moscatilin-inhibited vascular calcification by the classical WNT/β-catenin pathway, among which WNT3 played a key role in this process. …”
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Breastfeeding empowerment and its relationship with health literacy and spousal support among breastfeeding mothers in Tabriz, Iran: a cross-sectional study by Mojgan Mirghafourvand, Mina Hosseinzadeh, Shaqayeq Targhaq, Zahra Mousavi

“…Background Breast milk is crucial for the health and survival of infants, but exclusive breastfeeding often fails due to various reasons such as lack of breastfeeding empowerment.Objectives This study aimed to determine the status of breastfeeding empowerment and its relationship with health literacy and perceived spousal support among breastfeeding mothers while recognising that other related factors also contribute to breastfeeding empowerment.Design Cross-sectional study.Setting Primary health centres of Tabriz city, Iran.Participants Included 342 breastfeeding mothers with infants aged 6 months or younger in Tabriz, Iran.Results The mean (SD) scores for breastfeeding empowerment, health literacy and partner support were 141.98 (33.92) out of a possible range of 37 to 185, 126.08 (21.27) out of a possible range of 33 to 165 and 64.95 (12.62) out of a possible range of 20 to 100, respectively. …”
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Effect of healthy lifestyle score trajectory on all-cause mortality in the late middle-aged and older population: Finding from 17-year retrospective cohort study by Jeong Min Yang, Jieun Hwang

“…Methods: After excluding missing values, data from 6249 participants were analyzed using the group-based trajectory model (GBTM) to classify HLST, based on the first to fourth waves of the Korean Longitudinal Study of Aging (KLoSA). …”
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Reliability of Spatiotemporal Characteristics During Single-Legged Hop and Bilateral Drop Jump Tasks Using an Instrumented Pressure Walkway by Matthew McManigal, Austin Post, Michael Allen, Alyx Jorgensen, MIke Rosenthal, Michael Wellsandt, Matthew Tao, Elizabeth Wellsandt

“… # Study Design Cross-Sectional Study # Methods Individuals (n=38) in this cross-sectional study performed single, triple, and 6m hop tests on a pressure-sensitive Zeno walkway. Twenty-one participants completed follow-up testing between one and 14 days later. …”
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The formula for Peace as a result of a future without war in Ukraine by M. Pyvovar

“…This process largely depends on the active participation and support of the international community, which must be ready not only politically, but also practically to assist in the implementation of peace agreements. …”
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Systemic disease activity measured with ESSDAI varies largely over 5 years in a prospective, longitudinal cohort of patients with Sjögren’s disease by Suzanne Arends, Arjan Vissink, Hendrika Bootsma, Liseth de Wolff, Gwenny Verstappen, Alja Stel, Greetje van Zuiden, Jolien van Nimwegen, Frans Kroese

“…Objectives The objectives are to evaluate variation in systemic disease activity (European Alliance of Associations For Rheumatology (EULAR) Sjögren’s Syndrome Disease Activity Index (ESSDAI)) over time at group and individual patient level and to assess associations of ESSDAI low disease activity (LDA) with other outcome measures in a standard-of-care cohort of patients with Sjögren’s disease (SjD).Methods Patients with SjD participating in a prospective longitudinal study (REgistry of Sjögren Syndrome LongiTudinal cohort) fulfilling the 2016 American College of Rheumatology/EULAR classification criteria with ≥2 years of follow-up were included. …”
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