How does playfulness (re)frame the world? Evidence for selective cognitive and behavioral redirecting in times of adversity by Xiangyou Shen, Zoe Crawley

“…Sequential analyses including MANOVA, ANOVA, and ANCOVA were performed to examine overall, univariate, and adjusted group differences, respectively, validated by sensitivity analysis across three group categorization methods.ResultsThree sets of contrasting findings evidenced selective playful (re)framing effects, wherein more playful individuals (1) shared similar perceptions of current risk and protective factors while adopting a more optimistic future outlook, (2) perceived similar levels of vulnerability and isolation but engaged in significantly higher levels of resilient coping and adaptive leisure, and (3) participated in similar categories and frequencies of leisure activities but with higher experiential quality, marked by greater immersion, activeness, and positive affect.DiscussionPlayfulness functions as a “color spotlight” rather than “rose-tinted glasses,” with selective influence through “lemonading”—creatively imagining and pursuing positive possibilities to cultivate adaptive, enjoyable experiences while maintaining a clear-eyed realism about challenges. …”
Get full text

Effects of Metformin Added to Insulin in Adolescents with Type 1 Diabetes: An Exploratory Crossover Randomized Trial by Daizhi Yang, Jinhua Yan, Hongrong Deng, Xubin Yang, Sihui Luo, Xueying Zheng, Jing Lv, Wen Liang, Mengjie Hong, Zekai Wu, Bin Yao, Jianping Weng, Wen Xu

“…This was an exploratory, crossover, randomized trial conducted in adolescents with type 1 diabetes aged 12-18 years old. Participants were randomly received metformin (≤1000 mg/d) added to insulin for 24 weeks followed by insulin monotherapy for a subsequent 24 weeks or vice versa. …”
Get full text

Opportunities for the further development of the Safety Case for deep geological repositories by transdisciplinary research – FEP catalogs and scenario development by Marcel Ebeling, Martina Heiermann, Klaus-Jürgen Röhlig

“…In TRANSENS, it was proven that the participation of non-experts in research can lead to substantive and in-depth suggestions for improvement. …”
Get full text

Clinical depression prevalence and associated factors among adolescents with sickle cell anemia in dar es salaam, tanzania: a cross-sectional study by Linda Paul Athman, Agnes Jonathan, Fatima Musa, Honesta John Kipasika, Isihaka Mahawi, Florence Urio, Mwashungi Ally, Ritah Mutagonda, Lulu Chirande, Julie Makani, Emmanuel Balandya

“…Specifically, 167 participants (38.7%) had mild depression, 44 (13.5%) had moderate depression, 4 (1.2%) had moderately severe depression, and 1 (0.3%) had severe depression. …”
Get full text

Mechanism of TGIF1 on glycolipid metabolism disorders in mice with type 2 diabetes by Yuchen Li, Li Tao, Shikai Wang, Fuyan Bai, Liping Zheng, Lijun Hou

“…TGIF1 was enriched on the miR-106b-5p promoter and promoted miR-106b-5p expression. miR-106b-5p inhibited EGR2 expression. miR-106b-5p inhibition or EGR2 overexpression partially reversed the alleviative effect of TGIF1 overexpression on glycolipid metabolism disorders.Conclusion TGIF1 reduces glycolipid metabolism disorders in mice with T2D through the miR-106b-5p/EGR2 axis.…”
Get full text

Components of cognitive–behavioural therapy for mitigating core symptoms in attention-deficit hyperactivity disorder: a systematic review and network meta-analysis by Sayo Hamatani, Kazuki Matsumoto, Yoshihiko Kunisato, Yoshifumi Mizuno

“…This review included only randomised controlled trials.Findings 43 trials with 3817 participants were included in the network meta-analyses. …”
Get full text

LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress by Ying Yi, Min-Yu Wu, Kai-Tian Chen, An-Hai Chen, Lin-Qiu Li, Qin Xiong, Xian-Ren Wang, Wen-Bin Lei, Guan-Xia Xiong, Shu-Bin Fang

“…In conclusion, our study revealed that glycolysis-related LDHA was reduced in oxidative stress-induced SV-ECs, and that LDHA inhibition in SV-ECs elicited anti-inflammatory effects on Mφ, at least partially through the CX3CL1-CX3CR1 pathway. These findings suggest that LDHA represent a novel therapeutic strategy for the treatment of NIHL.…”
Get full text

Characterising “obesogenic” versus “protective” food consumption, and their value chain among Ghanaian households by Reginald Adjetey Annan, Nana Ama Frimpomaa Agyapong, Robert Aidoo, Charles Apprey, Linda Nana Esi Aduku, Elizabeth C Swart

“…Setting: Rural and urban communities in the Ashanti Region and selected retail/wholesale/producers nationwide. Participants: 612 households, 209 retailers and 185 wholesalers/distributors. …”
Get full text

A scoping review key elements and effects of cardiovascular disease management programs based on community-based participatory research. by Juhyeon Yang, Bohyun Park

“…Regarding application of the CBPR principles, community partners participated only in executing the research, not in analysing and interpreting research results. …”
Get full text

Multilevel determinants of racial/ethnic disparities in severe maternal morbidity and mortality in the context of the COVID-19 pandemic in the USA: protocol for a concurrent triang... by Bankole Olatosi, Jiajia Zhang, Xiaoming Li, Chen Liang, Jihong Liu, Peiyin Hung, Shan Qiao, Berry A Campbell, Myriam E Torres, Neset Hikmet

“…Informed consent will be provided by the participants in the in-depth interviews. Study findings will be disseminated with key stakeholders including patients, presented at academic conferences and published in peer-reviewed journals.…”
Get full text

Study protocol for a randomised-controlled study on emotion regulation training for adolescents with major depression: the KONNI study by Ellen Greimel, Lisa Feldmann, Charlotte Piechaczek, Frans Oort, Jürgen Bartling, Martin Schulte-Rüther, Gerd Schulte-Körne

“…In the CR training, participants will be instructed to downregulate negative affective responses to negative pictures via CR, while the control training involves picture viewing. …”
Get full text

Low back pain and associated factors among obstetrics care providers in public hospitals of Amhara Regional State, Ethiopia: a cross-sectional study by Bitew Tefera Zewudie, Bogale Chekole Temere, Muche Argaw Eniyew, Yibeltal Mesfin, Shegaw Geze Tenaw

“…The objective of this study was to assess the prevalence and associated factors of LBP among obstetrics care providers in public hospitals in Amhara Regional State, Ethiopia.Design An institution-based cross-sectional study.Settings The study settings were nine public hospitals in Amhara Region.Participants Randomly selected 416 obstetrics care providers working in public hospitals in Amhara Region, Ethiopia.Outcomes The outcomes of this study were the prevalence of LBP in the last 12 months among obstetrics care providers and its associated factors.Results Overall, the prevalence of LBP was 65.6% (95% CI 61.5% to 70.2%) among obstetrics care providers in the last 12 months.Female gender (AOR 2.33, 95% CI 1.344 to 4.038), not having regular physical exercise habits (AOR 8.26, 95% CI 4.36 to 15.66), job stress (AOR 2.21, 95% CI 1.24 to 3.92), standing longer while doing procedures (AOR 2.04, 95% CI 1.14 to 3.66) and working more than 40 hours a week (AOR 2.20, 95% CI 1.09 to 4.45) were significantly associated with LBP.Conclusion About two-thirds of obstetrics care providers working in public hospitals in the Amhara region reported LBP. …”
Get full text

The reliability, sensitivity and specificity of fluorescent oxidation products for measuring global oxidative stress in vivo by Bing Liang, Juan Zhang, Xue Shen, Xiaohua Zhang, Ann M. Vuong, Linghua Yang, Xinyan Shi, Xueru Ge, Huan He, Tong Liu, Shuman Yang

“…Results At a 1:20 (plasma/extractant) mixture ratio, the overall inter-/intra-assay coefficients of variation (CV) for FlOP measurements among healthy and coronary heart disease participants were <3.6%/<2.7% and <4.4%/<2.0%, respectively. …”
Get full text

Plant and soil responses to ground-mounted solar panels in temperate agricultural systems by Fabio Carvalho, Hannah Montag, Laura Bentley, Radim Šarlej, Rosanne C Broyd, Hollie Blaydes, Marta Cattin, Miranda Burke, Abby Wallwork, Sammani Ramanayaka, Piran C L White, Stuart P Sharp, Tom Clarkson, Alona Armstrong

“…Soil organic carbon was 9% lower under solar panels than in gaps, while particulate organic matter was 29.1% and 23.6% lower under solar panels than in gaps and pastures, respectively. …”
Get full text

Obstetric and pregnancy-related factors associated with caesarean delivery in Bangladesh: a survey in Rajshahi district by Md Aslam Hossain, Md Reazul Karim, Md Golam Hossain, Abu Sayed Md Al Mamun, Md Abdul Awal, Jarin Sazzad

“…This study aimed to identify emerging obstetric and pregnancy risk factors and maternal outcomes associated with CS delivery among women in Rajshahi district, Bangladesh.Design This was a cross-sectional study.Setting Data were collected from 9 Upazilas with 233 community clinics of Rajshahi district, Bangladesh.Participants Multistage sampling technique was utilised for selecting sample from the population. …”
Get full text

The History of the Creation and Promotion of the First Consolidated Text of the Bashkir Folk Epic “Idukai and Muradim” by Khabutdinova M.M.

“…In the second half of 1920s to the first half of 1930s, Naki Isanbet participated in the first academic project in Russian history to collect, study, and create critical texts of epics of the peoples of the USSR, headed by scientists of the USSR Academy of Sciences. …”
Get full text

Associations of four obesity indices with diabetes mellitus in Korean middle-aged and older adults using the Korean Genome and Epidemiology Study (KoGES) by Yiseul Lee, Nam-Kyoo Lim, Hyun-Young Park

“…Results Among the 160,585 participants, 13,846 had DM (6,837; men [11.86%] and 7,009 women [6.81%]). …”
Get full text

Goal attainment scaling as an outcome measure for randomised controlled trials: a scoping review by Elaine Pascoe, Andrea Viecelli, Ruth Hubbard, Benignus Logan, Dev Jegatheesan

“…Data collected underwent descriptive statistics.Results Of 1,838 articles screened, 38 studies were included. These studies were most frequently conducted in rehabilitation (58%) and geriatric medicine (24%) disciplines/populations. …”
Get full text

Cyclical Inclusive Growth Model of the European Union by E. V. Sapir, A. D. Vasilchenko

“…This article analyzes the distinctive features of the contemporary cyclical inclusive growth model within the European Union (EU). …”
Get full text

Association between albumin corrected anion gap and in-hospital mortality in critically ill patients with chronic obstructive pulmonary disease by Mohan Giri, Anju Puri, Lan Huang, Shuliang Guo

“…The receiver operating characteristic (ROC) curve was used to determine the optimal threshold for ACAG, and participants were divided into two categories based on this threshold. …”
Get full text