Skeletal progenitor LRP1 deficiency causes severe and persistent skeletal defects with Wnt pathway dysregulation by Mohammad Alhashmi, Abdulrahman M. E. Gremida, Santosh K. Maharana, Marco Antonaci, Amy Kerr, Shijian Fu, Sharna Lunn, David A. Turner, Noor A. Al-Maslamani, Ke Liu, Maria M. Meschis, Hazel Sutherland, Peter Wilson, Peter Clegg, Grant N. Wheeler, Robert J. van ‘t Hof, George Bou-Gharios, Kazuhiro Yamamoto

“…In the developing limbs, LRP1 partially colocalises with Wnt5a and its deficiency alters abundance and distribution of Wnt5a and Vangl2. …”
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Portable devices for periodic monitoring of bioelectrical impedance along meridian pathways in healthy individuals by Yu-Chen Xu, Xiu-Yan Cao, Shuai Liu, Bo Liu, Hao Chen, Min Cheng, Wei-Hua Ye

“…Methods A cohort of 684 healthy middle-aged participants from North China was enrolled between July 1, 2017, and September 5, 2020. …”
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Effectiveness of home-based walking exercise for patients with peripheral artery disease and intermittent claudication: a systematic review and meta-analysis by Zheng Xu, Jing Chuo, Xiaoqin Zhao

“…Objective This study aimed to assess the effect of home-based exercise interventions on walking performance in patients with peripheral artery disease (PAD) and intermittent claudication (IC).Design Systematic review and meta-analysis.Data sources We searched the Medline, Web of Science, Embase, Scopus and Cochrane Library databases to identify randomised controlled trials of patients with PAD and IC published in English up to August 2024.Eligibility criteria Randomised controlled trials of patients who participated in home-based exercise interventions and were assessed for walking performance were eligible for inclusion. …”
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Redefining the Mode of HIV Transmission through Analysis of Risk Attribution among the Reported HIV Cases from 1993 to 2021 in Bhutan by Lekey Khandu, Ngawang Choida, Jurmi Drukpa, Dolley Tsehring, Sonam Wangdi

“…We have sought ethics approval and obtained participants’ informed consent. Results. The risk attribution analysis showed that 81.94% of HIV infection among the reported HIV cases in Bhutan has occurred through high-risk heterosexuals and 8.88% through mother-to-child transmission, and parenteral transmission accounts for 1.58% and then 1.35% through homosexual. …”
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Acupuncture as a Therapeutic Intervention for Alleviating Pain Associated with Knee Osteoarthritis in the Elderly by Ida Ayu Suptika Strisanti, Ida Ayu Anom Rastiti, Kadek Buja Harditya, I Dewa Ayu Agra Darmawati, Komang Rosa Tri Anggaraeni

“…All respondents provided informed consent before participating in the study. The Wilcoxon Signed Rank Test was used to analyze and interpret the results. …”
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Influence of College Teacher’s Instructional Design on the Development of College Students’ Thinking of Innovation Multi-Algorithms Perspective Analysis by Leilei Wang, Jie Zhou, Xinying Li

“…It makes it possible to personalize learning, share open data, have real-time debates, and participate in a variety of virtual learning activities. …”
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Socioeconomic factors associated with the number of children ever born by married Ghanaian females: a cross-sectional analysis by Felix Boakye Oppong, Divine Darlington Logo, Dennis Boateng, Ephraim Kumi Senkyire

“…Bivariate and multivariate analyses were considered for all models.Setting The study was conducted in all 10 administrative regions of Ghana.Participants Married females aged between 15 and 49 years.Primary and secondary outcome measures Socioeconomic factors associated with married females’ CEB.Results In all three models, place of residence, zone, wealth index, age, age at marriage, media exposure, level of education, number of abortions and age at first sex were all significantly (p<0.05) associated with CEB. …”
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Family participatory clown therapy in venipuncture in hospitalized children: A non-randomized controlled trial. by Tianyu Chen, Qiying Chen, Zhenhua Lin, Jingfang Ye

“…<h4>Methods</h4>We recruited 104 children aged 3 to 6 years for a non-randomized controlled trial from March to December 2022. All participants required peripheral venepuncture infusions for treatment. …”
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Impact of the COVID-19 pandemic on primary care for hypertension in the UK: a population-based cohort study by Christel Renoux, James M. Brophy, Kyle Johnson, Sarah Beradid, Robert W. Platt

“…Objectives To describe the impact of the COVID-19 pandemic on hypertension diagnosis and management in UK primary care.Design Population-based cohort study.Setting Over 2000 general practices across the UK contributing to the Clinical Practice Research Datalink.Participants A cohort of 23 076 390 patients over 18 years of age and registered with their general practice for at least 1 year between 2011 and 2022, who did not have a previous diagnosis of hypertension. …”
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Perceptions of climatic variability among millet farmers: insights from tribal communities in the Kolli Hills, Tamil Nadu, South India by Rajendra R. Chapke, C. Tara Satyavathi, E. D. Israel Oliver King, Peddiveeti Laxmiprasanna, Vavilala Priyanka

“…Most of the tribal farmers perceived that climate change substantially impacts low-resourced farmers’ ability to secure their livelihoods. Social participation and mass media utilization were positively correlated with tribal farmers’ perception of climatic variability. …”
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Impact of the COVID-19 pandemic on epidemiological and clinical characteristics of inpatients with burns in a Northwest China burn centre: a retrospective study by Jiaqi Liu, Jian Feng, Yuheng Zhang, Yiwei Cui, Shuao Xiao, Yige Han, Yongqian Bian, Xueyong Li

“…Objective This study aimed to assess the impact of the COVID-19 pandemic on the characteristics and outcomes of patients with burns in a burn centre situated in Northwest China.Design A retrospective descriptive study.Setting This study was conducted in Tangdu Hospital, a major regional burn centre in Xi'an, Shaanxi Province of China.Participants A total of 1413 patients with burns were included in the study, with the admission period spanning from 2017 to 2019 (before the pandemic) and 2020 to 2022 (during the pandemic).Results Burn hospitalisations decreased during the pandemic for both children (9.80%) and adults (24.68%). …”
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Evaluating the effect of virgin coconut oil pulling on viral load, bacterial load and inflammatory mediator levels in chronic periodontitis – A clinical study by Monika M, Rudhra K, Vennila K, Elanchezhiyan, Sri Harini P, S. Shakeron

“…Pre-operative subgingival plaque samples were collected from all participants, followed by complete scaling and root planing. …”
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LONGITUDINAL STUDIES OF MUSICALLY GIFTED SCHOOLGIRLS by Svetlana N. Loseva

“…The aim of the article is to consider the empirical aspects of the development of musical gifted schoolgirls in vocal and choral activities.Methods. …”
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Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin by Michał Biernacki, Elżbieta Skrzydlewska

“…Phospholipids are subject to continuous transformation, including enzymatic hydrolysis (with the participation of phospholipases A, C, and D) to free polyunsaturated fatty acids (PUFAs), which under the influence of cyclooxygenases (COX1/2), lipoxygenases (LOXs), and cytochrome P450 (CYPs P450) are metabolized to various classes of oxylipins, depending on the type of PUFA being metabolized and the enzyme acting. …”
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An Analysis of the Impact of Digital Therapeutic Interventions on Attention and Working Memory in Children with Attention-Deficit/Hyperactivity Disorder: A Randomized Controlled Tr... by Seon-Chil Kim, Hojun Lee

“…It tracks quantitative changes to evaluate improvements in concentration and working memory when digital game-based content is used as adjunct therapy alongside medication for children with ADHD. Thirty children participated; one group received digital therapeutic intervention based on game content alongside medication (experimental) and the other group received conventional treatments (control). …”
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Surveillance of drug prescribing: why outliers miss their targets – a qualitative study by Julia Gollnick, Nikoletta Zeschick, Franziska Hörbrand, Peter Killian, Maria Sebastiao, Thomas Kühlein, Norbert Donner-Banzhoff

“…Outliers were invited to participate in semi-structured interviews. Results Out of 401 outliers thus identified n = 26 physicians were interviewed. …”
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Relationship between psychological empowerment, physical activity enjoyment, and response to a HIIT Program in physically inactive young women: a prospective multicentre study by Irene Ferrando-Terradez, Rodrigo Núñez-Cortés, Laura López-Bueno, Enrique Alcántara, Joaquín Calatayud, José Casaña, Ivana Parčina, Lirios Dueñas

“…Methods A total of 61 physically inactive young women (age: 20.1 ± 2.7 y) were recruited to participate in a six-month HIIT intervention delivered via a smartphone app. …”
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Factors Influencing Non-Attendance of Elderly at Rural and Urban Comprehensive Health Centers from Healthcare Providers' Perspective by Sasan Ghorbani Kalkhajeh, Bagher Pahlavanzadeh, Ramin Tabibi, Mohammad Mahboubi

“…Results. The majority of participants in this study were female (77.81%), married (74.26%), and had a bachelor's degree (32.25%). …”
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Evaluating the Performance of Low-cost PM Sensors over Multiple COALESCE Network Sites by Vishal R. Dharaiya, Vasudev Malyan, Vikas Kumar, Manoranjan Sahu, Chandra Venkatraman, Pratim Biswas, Kajal Yadav, Diksha Haswani, Ramya Sunder Raman, Ruqia Bhat, Tanveer Ahmad Najar, Arshid Jehangir, Rohit P. Patil, G. Pandithurai, Sandeep Singh Duhan, Jitendra Singh Laura

“…Abstract Air quality is a global concern, with particulate matter receiving considerable attention due to its impact on human health and climate change. …”
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FORMATION OF MEDIA COMPETENCE OF FUTURE DOCTORS IN THE PROCESS OF PRECLINICAL PROFESSIONAL TRAINING: PSYCHOLOGICAL AND PEDAGOGICAL CONDITIONS by Olena Murzina

“…The article theoretically substantiates the psychological and pedagogical conditions for the formation of media competence of future doctors in the process of preclinical professional training at the medical university. …”