Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity by Sophia Lazar, Jeremy G.T. Wurtzel, Shayan Askari, Matthew Cooper, Xuefei Zhao, Peisong Ma, Lawrence E. Goldfinger

“…Thus, Ago2 is important for platelet development and function, putatively partially rescued by upregulation of Ago1. Platelet reactivity controlled by Ago2 reflects sex-specific regulation of gene expression potentially at both transcriptional and translational levels in megakaryocytes and platelets.…”
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Impact of Concussions on Postural Stability Performance Using the Head Shake-Sensory Organization Test by John D Heick, Abdulaziz Alkathiry

“… # Results Twenty-five participants (nine patients with history of concussion and 16 healthy controls; mean age, 21.08±4.10 years) completed testing. …”
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Marital Status and Survival in Patients Diagnosed with Melanoma by J. A. Maas, A. J. Monreal, E. L. Diaz, G. Castro, P. Rodriguez de la Vega, M. Varella

“…We performed secondary analysis of data from all participants of the Florida Cancer Data System (FCDS) and included adult melanoma patients diagnosed between 2001 and 2009 with follow-up information available until 2015. …”
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Comparison of In Vitro Biotransformation of Olive Polyphenols Between Healthy Young and Elderly by Stef Lauwers, Anne-Sophie Weyns, Annelies Breynaert, Tim Van Rillaer, Valerie Van Huynegem, Erik Fransen, Wout Bittremieux, Sarah Lebeer, Emmy Tuenter, Nina Hermans

“…Methods: An in vitro biotransformation model was used to mimic the conditions in the stomach, small intestine and colon of two age groups of healthy participants (20–30 years old, ≥65 years old), using oleuropein as a single compound and an olive leaf extract as test compounds. …”
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Efficacy of Cognitive Behavioral Therapy in Divorced Women for Depression, Anxiety and Loneliness symptoms: A pilot study by Nilgün ÖNGÝDER

“…The sample of the study consisted of 7 divorced women. The participants was selected from women whom was divorced between 0-2 years. …”
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A novel classification method for balance differences in elite versus expert athletes based on composite multiscale complexity index and ranking forests. by Yuqi Cheng, Dawei Wu, Ying Wu, Youcai Guo, Xinze Cui, Pengquan Zhang, Jie Gao, Yanming Fu, Xin Wang

“…We calculated the CMCI and used four machine learning algorithms-Logistic Regression, Support Vector Machine(SVM), Naive Bayes, and Ranking Forest-to combine these features and assess each participant's balance ability. A classic train-test split method was applied, and the performance of different classifiers was evaluated using Receiver Operating Characteristic(ROC) analysis. …”
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Comparative study between efficacy of topical tofacitinib 2% ointment versus topical clobetasol propionate 0.05% ointment in hand eczema at a tertiary hospital in central India [ve... by Dr Adarshlata Singh, Drishti Bhatt

“…Methods The study will be a single-blinded, parallel-group, randomized controlled trial conducted at the Dermatology outpatient department of Acharya Vinoba Bhave Rural Hospital Sawangi Meghe, Wardha, from March 2023 to September 2025. Eligible participants diagnosed with hand eczema will be randomized into two groups: Group 1 will receive Clobetasol Propionate 0.05% ointment, and Group 2 will receive Tofacitinib 2% ointment. …”
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A novel validation approach shows new, solid reasons why vertical jump height should not be used to predict leg power by Luis Fernando Aragón-Vargas, María Isabel González-Lutz

“…Second, three young male participantsperformed 50 maximal jumps each. Participants rested for 1 minute between jumps. VJP was calculated from kinematic data as peak body center of mass (BCOM) minus standing BCOM; peak power (PEAKPWR) was calculated from the vertical ground reaction force registered by a force plate, and average power(MEANPWR) during propulsion from the change in potential energy of BCOM. …”
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Positive Stress and Reflective Practice Among Entrepreneurs by Kati Tikkamäki, Päivi Heikkilä, Mari Ainasoja

“…The research process was designed to support reflective dialogue among the 21 Finnish entrepreneurs from different fields who participated in the study, with results based mainly on qualitative interviews. …”
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Association between magnesium depletion score and prevalence of hyperuricemia in American adults: a study based on NHANES 2007-2018 by Yongchun Xiao, Yong Mou, Yong Mou, Ping Wu, Ke Wang, Tianjun Chen, Zhiwan Chen, Hongsheng Lin, Hua Yang, Zhisheng Ji

“…Subgroup and sensitivity analyses, including the exclusion of gout patients, further evaluated this association.ResultsAmong 18,761 participants, higher MDS were associated with an increased prevalence of HUA. …”
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Understanding co-production of injury research in Australian Aboriginal and Torres Strait Islander communities: a comprehensive scoping review by Genevieve Westacott, Victoria McCreanor, Susanna Cramb, Silvia Manzanero, Kim Vuong, Michelle Allen, Shannon Dias, Geoffrey Binge, Arpita Das

“…Co-production methodologies offer opportunities for research to be developed collaboratively ensuring meaningfulness of results and appropriate protection for participants. A scoping review was undertaken to investigate the use of co-production methodologies in research within the unintentional injuries space for Australian Aboriginal and Torres Strait Islander communities over time. …”
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Association between cardiac autonomic regulation, visceral adipose tissue, cardiorespiratory fitness and ambient air pollution: 4HAIE study (Program-4). by Tomas Dostal, Martina Dankova, Tomas Barot, Dominik Sindler, Petr Kutac, Vera Jandackova, Daniel Jandacka, Peter Hofmann, Lukas Cipryan

“…<h4>Methods</h4>The study sample included 1036 (487 females) healthy runners (603) and inactive participants (age 18-65 years) who had lived for at least 5 years in an area with high (Moravian-Silesian; MS) or low (South Bohemian; SB) air pollution in the Czech Republic. …”
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Proinflammatory Cytokine IL-6 and JAK-STAT Signaling Pathway in Myeloproliferative Neoplasms by Vladan P. Čokić, Olivera Mitrović-Ajtić, Bojana B. Beleslin-Čokić, Dragana Marković, Marijana Buač, Miloš Diklić, Nada Kraguljac-Kurtović, Svetozar Damjanović, Pavle Milenković, Mirjana Gotić, Puri K. Raj

“…Therefore, the JAK2V617F mutant allele burden participated in inflammation biomarkers induction and related signaling pathways activation in MPNs.…”
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Digital literacy as a basis for a dialogue between the authorities and the population in the context of a pandemic by N. V. Prokazina

“…Tools that ensure the involvement of public participation in management processes in a digital environment (as infrastructure components) have been created and are actively developing, and the presence of a basic level of digital competence of citizens allows you to include a large part of the population in these processes. …”
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Assessment of rural satisfaction with local organizations services In ILAM province by Alireza darban astaneh

“…Today in democratic governments, accountability to people and obtain the consent of them form local services is important for people's participation in local governance and consequently it is important to organizational success. …”
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Does candidate race influence simulated patient ratings in standardised assessments of clinical practice? A single-blinded randomised study in UK medical schools by Celia Brown, Amir H Sam, Rachel Westacott, Mark Gurnell, Sarah Khavandi, Malcolm Reed, Ann Sebastian, Kerry Badger

“…This study aimed to determine whether being a non-white candidate affected scoring by simulated patients, compared with a white candidate, at three different performance grades in the same history-taking station.Design Single-blinded, video-based, randomised study.Participants 163 simulated patients watched a randomly allocated set of six videos. …”
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Deep learning on CT scans to predict checkpoint inhibitor treatment outcomes in advanced melanoma by Laurens S. Ter Maat, Rob A. J. De Mooij, Isabella A. J. Van Duin, Joost J. C. Verhoeff, Sjoerd G. Elias, Tim Leiner, Wouter A. C. van Amsterdam, Max F. Troenokarso, Eran R. A. N. Arntz, Franchette W. P. J. Van den Berkmortel, Marye J. Boers-Sonderen, Martijn F. Boomsma, Fons J. M. Van den Eertwegh, Jan Willem de Groot, Geke A. P. Hospers, Djura Piersma, Art Vreugdenhil, Hans M. Westgeest, Ellen Kapiteijn, Ardine A. De Wit, Willeke A. M. Blokx, Paul J. Van Diest, Pim A. De Jong, Josien P. W. Pluim, Karijn P. M. Suijkerbuijk, Mitko Veta

“…Adult patients that were treated with ICI for advanced melanoma were retrospectively identified from ten participating centers. A deep learning model (DLM) was trained on volumes of lesions on baseline CT to predict clinical benefit. …”
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Slabless Staircase Flexural Behavior with Multi Reinforcement Configuration by Rafal saeed Rafal saeed s.

“…They employ a series of open or partially supported steps, often reinforced by central support structures or narrow risers. …”
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An expert perspective on diversity-oriented standards for assessing sex and gender in clinical research by Hannah R. Hambruch, Nora M. Laskowski, Robert-Paul Juster, Georg Halbeisen, Georgios Paslakis

“…Consensus was defined as 70% agreement or disagreement.Results14 out of 17 participating experts agreed on the importance to independently assess sex assigned at birth, and 9 out of 16 emphasized this for gender identity in clinical trials. …”
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Arthroplasty registries at a glance: an initiative of the International Society of Arthroplasty Registries (ISAR) to facilitate access, understanding, and reporting of registry dat... by Anne Lübbeke, Lotje A Hoogervorst, Perla J Marang-van de Mheen, Heather A Prentice, Ola Rolfson, Rob G H H Nelissen, Arnd Steinbrück, Gearoid McGauran, Christophe Barea, Kajsa Erikson, Alma B Pedersen, Martyn Porter

“…All 29 ISAR member registries as of July 2023 were invited to participate in the project. Results: Included items covered general descriptive information regarding registries, information related to governance, outcomes, data quality, data access, and registry production. …”
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