Knowledge, attitude and practice regarding screening and managing diabetic microvascular complications among general practitioners of community health centres: a cross-sectional st... by Hua Yang, Jian Gao, Ying Yu, Cuiling Huang, Chengdian Lan, Zhangyan Chen

“…Objective To evaluate the knowledge, attitude and practice (KAP) regarding screening and managing diabetic microvascular complications, encompassing diabetic retinopathy (DR), diabetic kidney disease (DKD) and diabetic neuropathy (DN), among general practitioners (GPs).Design Cross-sectional study.Setting The online questionnaire survey was conducted between April and July 2023.Participants GPs from community health centres (CHCs) in all 16 districts of Shanghai were recruited.Primary and secondary outcome measures The data of sociodemographic characteristics, KAP scales, training experience and screening instruments for community screening and managing diabetic microvascular complications were collected. …”
Get full text

Iodine Deficiency Disorder and Knowledge about Benefit and Food Source of Iodine among Adolescent Girls in the North Shewa Zone of Amhara Region by Abayneh Birlie Zeru, Mikyas Arega Muluneh, Kassa Ketsela H Giorgis, Mulat Mossie Menalu, Michael Amera Tizazu

“…Over half, 216 (55.1%), of 392 (62.7%) participants who had knowledge about the benefit of iodine knew it prevents goiter. …”
Get full text

Trends and determinants of obesity among ever-married women aged 15–49 in India: insights from National Family Health Surveys (NFHS 1998–2021) by Aditya Singh, Sadanand Karun, Mahashweta Chakrabarty, Rakesh Chandra, Shivani Singh

“…Methods Data from four National Family Health Survey (NFHS) rounds, spanning 1998-99 to 2019-21, were pooled to create a dataset of 1,117,433 participants. We analysed obesity trends in India and its states and assessed β- and σ-convergence in obesity rates during this period. …”
Get full text

RETRACTED: Long non‐coding RNA Sox2OT promotes coronary microembolization‐induced myocardial injury by mediating pyroptosis by Liying Xuan, Danni Fu, Dong Zhen, Dongsong Bai, Lijun Yu, Guohua Gong

“…In addition, miR‐23b overexpression could supplement the cytosolic miR‐23b reserves to target TLR‐4 and partially reverse Sox2OT‐mediated pyroptosis in LPS‐treated H9C2 cells. …”
Get full text

Are psychological attitudes towards vaccination an expression of personality? A cross-sectional study on COVID-19 vaccination in France by Gaëlle Lièvre, Jonathan Sicsic, Simon Galmiche, Tiffany Charmet, Arnaud Fontanet, Judith Mueller

“…Results Among the 49,019 participants, 95.0% reported receipt of at least one dose and 89.8% were up to date with recommendations. …”
Get full text

Digital health data security practices among health professionals in low-resource settings: cross-sectional study in Amhara Region, Ethiopia by Ayenew Sisay Gebeyew, Wondwossen Zemene, Binyam Chaklu Tilahun, Nebyu Demeke Mengestie, Berhanu Fikade Endehabtu, Zegeye Regasa Wordofa, Mitiku Kassaw Takillo, Gedefaw Belete Ashagrie, Melaku Molla Sisay

“…A simple random sampling technique was used for the study participants. Then, self-administered questionnaires were administered. …”
Get full text

Food safety practice and its associated factors among food handlers working in food and drinking establishments in Hargeisa, Somaliland by Mohamed Mussa Abdilahi, Jonah Kiruja, Abdisamad Shukri Ismail, Soheir H. Ahmed, Faisal Nooh, Ayanle Suleiman Ahmed, Abdiqathar Rashid Kulmie

“…Results In this study, a total of 306 food handlers participated. The majority (85.3%) of food handlers was males and 84% had non-formal education. …”
Get full text

The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e... by Biao Peng, Mu-Yun Yan, Yun-Rong Chen, Fei Sun, Xu-Dong Xiang, Da Liu

“…The methyl-CpG binding domain protein 2 (MBD2) participates in neutrophil-mediated severe asthma through epigenetic regulation. …”
Get full text

Knowledge, Attitude, and Associated Factors towards Colostrum Feeding among Antenatal Care Attendant Mothers in Gununo Health Centre, Wolaita Zone, Ethiopia 2019: Cross-Sectional S... by Addisu Yeshambel Wassie, Natnael Atnafu Gebeyehu, Kelemu Abebe Gelaw

“…Results. Among the study participants 226 (66.1%) were knowledgeable and 39 (11.4%) were not knowledgeable on colostrum feeding. …”
Get full text

Positive end-expiratory pressure and risk of postoperative pulmonary complications in patients living at high altitudes and undergoing surgery at low altitudes: a single-centre, re... by Zhuoning Li, Kaixi Shang, Zongjing Xia, Xiaoli Ye, Chongcong Gong

“…Objectives To examine whether a high positive end-expiratory pressure (PEEP ≥5 cmH2O) has a protective effect on the risk of postoperative pulmonary complications (PPCs) in a cohort of patients living at high altitudes and undergoing general anaesthesia.Design Retrospective, observational study.Setting A tertiary hospital in China.Participants Adult Tibetan patients living at high altitudes (≥3000 m) and who went to the low-altitude plain to undergo non-cardiothoracic surgery under general anaesthesia, from January 2018 to April 2020.Measurements This study included 1905 patients who were divided according to the application of an intraoperative PEEP: low PEEP (<5 cmH2O, including 0 cmH2O) or high PEEP (≥5 cmH2O). …”
Get full text

Factors influencing role preferences in decision-making of healthy women with BRCA1/2 pathogenic variants: subanalysis from a randomised controlled decision coaching trial by Sibylle Kautz-Freimuth, Arim Shukri, Claudia Stracke, Anna Isselhard, Birte Berger-Höger, Anke Steckelberg, Frank Vitinius, Nicola Dikow, Marion Kiechle, Cornelia Meisel, Achim Wöckel, Marion Tina von Mackelenbergh, Rita Schmutzler, Kerstin Rhiem, Stephanie Stock

“…Conclusions High initial decisional conflict was identified as an important predictor for preferring and taking a passive role in decision-making among women with BRCA1/2 PVs. Participating in the DC programme can counteract passivating effects of an initially high decisional conflict and particularly support younger PV carriers and those with lower educational status to take an active role. …”
Get full text

Comparison of Glenohumeral Range of Motion Deficits in Youth, Collegiate, and Professional Baseball Players by C. Luke Wilcox, Hillary A. Plummer, Roger V. Ostrander III

“… # Results Two-hundred and twenty-three male baseball players ages 11-26 participated. The 12u (53.7°) and 14u (54.2°) groups had significantly less internal rotation than HS1 (65.2°), HS2 (63.9°), College (62.3°), Pro1 (64.9°), and Pro2 (64.5°) players (p<0.0001). …”
Get full text

Pilates exercise in pregnancy: a systematic review and meta-analysis by Yuxuan Li, Heran Lu, Liuwei Zhang, Yijia Ren, Xiaotong Dai, Lin Lin

“…Methods A thorough search was performed across 7 databases, focusing on articles published up to June 2024. The quality of evidence was assessed using the Cochrane RoB Tool, and STATA 17.0 software was utilized to perform tests for heterogeneity, publication bias, and sensitivity analysis. …”
Get full text

The impact of weight loss interventions on disordered eating symptoms in people with overweight and obesity: a systematic review &amp; meta-analysisResearch in context by Elena Tsompanaki, Dimitrios A. Koutoukidis, Gina Wren, Heather Tong, Annika Theodoulou, Danni Wang, Rebecca J. Park, Susan A. Jebb, Paul Aveyard

“…Findings: Thirty-eight studies with 66 eligible arms (61 interventions: 29 BWL, 11 BWL + pharmacotherapy, 20 BWL + psychological intervention, 1 pharmacotherapy + psychological intervention) and 3364 participants in total were included. The mean weight change was −4.7 kg (95% CI: −5.7, −3.7). …”
Get full text

Impact of COVID-19 on rheumatic diseases in india: Determinants of mortality and adverse outcome: A retrospective, cross-sectional cohort study by Avinash Jain, Vineeta Shobha, S Chandrashekara, Padmanabha Shenoy, Sapan C Pandya, Prakash Chotalia, Sharath Kumar, Sourabh Malviya, Yogesh Preet Singh, Abhishek Patil, Vikas Gupta, Puja Srivastava, Vijaya Prasanna Parimi, Chanakya Kodishala, Ramya Janardana, Benzeeta Pinto, Sudhir Bhandari, Govind Rankawat, Praveen Pratap Jadhav, Damodaram Potugari, Vishnu Sharma, Alpana Parmar, Sunitha Kayidhi, Paul T Antony, Ashish Badika, Amit Sharma

“…Methods: All registered members of IRA were invited to participate in this registry and provide information of reverse transcription–polymerase chain reaction confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)-infected RD patients using an online platform https://iradatabaseard.in/iracovid/index.php. …”
Get full text

Malaria prevalence, transmission potential and efficacy of artemisinin-based combination therapy in the Kenyan Central highlands: a zone previously characterized as malaria-free by Francis T. Kimani, Kelvin K. Thiongó, Maureen A. Otinga, Lewis K. Mbabu, Mary N. Ombati, Stanley K. Kitur, Sarah A. Ochieng’, Lucy N. Wachira, Damaris K. Matoke-Muhia, Luna Kamau

“…Conclusion The Plasmodium infections positivity rate observed in the study site was very low but significant. A proportion of participants who tested positive did not report recent history of travel. …”
Get full text

Management of childbearing with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders: A scoping review and expert co-creation of evidence-based clinical guidelin... by Sally Pezaro, Isabelle Brock, Maggie Buckley, Sarahann Callaway, Serwet Demirdas, Alan Hakim, Cheryl Harris, Carole High Gross, Megan Karanfil, Isabelle Le Ray, Laura McGillis, Bonnie Nasar, Melissa Russo, Lorna Ryan, Natalie Blagowidow

“…No language limitations were placed on our search, and our team had the ability to translate and screen articles retrieved in English, French, Spanish, Italian, Russian, Swedish, Norwegian, Dutch, Danish, German, and Portuguese. …”
Get full text

Temporal trends in guideline-recommended medical therapy after an acute heart failure decompensation event: an observational analysis from Generator Heart Failure DataMart by Antonio Gasbarrini, Giuseppe Patti, Filippo Crea, Giovanni Scambia, Domenico D'Amario, Vincenzo Valentini, Gianluigi Savarese, Alfredo Cesario, Jacopo Lenkowicz, Stefano Patarnello, Renzo Laborante, Agni Delvinioti, Andrada Mihaela Tudor, Chiara Iacomini, Antonio Iaconelli, Donato Antonio Paglianiti, Mattia Galli, Daniele Rodolico, Attilio Restivo, Giuseppe Ciliberti, Gaetano Rizzo, Emiliano Bianchini, Matteo Busti, Luca Sensini

“…Objectives To evaluate the trend of prescription of the four foundational therapies, and their impact on 30-day urgent re-admissions and all-cause death in patients with heart failure and reduced ejection fraction (HFrEF) following an acute decompensation event.Design Retrospective.Setting One tertiary referral centre.Participants 999 consecutively patients admitted with a primary diagnosis of HFrEF between January 2020 and June 2023 were identified through a validated, high‐performance technology infrastructure based on artificial intelligence. …”
Get full text

HLA-DMB correlates with antitumor immunity and an improved prognosis in endometrial carcinoma tumors by Xiaoyu Xi, Xiaona Zhang, Jianxin Tang, Xiumei Fan, Jiexian Du

“…Mechanistically, HLA-DMB primarily participates in CD22-mediated regulation of B cell receptors (BCR), leading to BCR antigen activation and the production of second messengers. …”
Get full text

Risk factors for COVID-19 hospitalisations and deaths in Mexican children and adolescents: retrospective cross-sectional study by Mauricio Hernandez-Avila, Libny Martínez-Valdez, Vesta Richardson López Collada, Luis Enrique Castro-Ceronio, Ángela María Rodríguez Gutiérrez, Aurora Bautista-Márquez

“…Objective To describe the epidemiology and risk factors for hospitalisation and death in Mexican children under 18 years of age with COVID-19.Design Retrospective, cross-sectional and analytical study.Setting Mexican Ministry of Health open databases with COVID-19 cases occurred from 7 March 2020 to 30 September 2021.Participants Mexican children under 18 years of age with COVID-19.Main outcome measures COVID-19 hospitalisations and deaths were characterised by age group, sex, presence of pneumonia and comorbidities, intubation and intensive care unit admission, and institution that provided medical care. …”
Get full text