Epigenetic Biomarkers and the Wnt/β-Catenin Pathway in Opisthorchis viverrini-associated Cholangiocarcinoma: A Scoping Review on Therapeutic Opportunities. by Alok Kafle, Sutas Suttiprapa, Mubarak Muhammad, Jan Clyden B Tenorio, Roshan Kumar Mahato, Norhidayu Sahimin, Shih Keng Loong

“…This process retrieved a total of 81 peer-reviewed research articles deemed eligible for inclusion, as they partially or fully met the pre-defined selection criteria. …”
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Concentric and Eccentric Force Changes with Elastic Band and Isotonic Heavy Resistance Training: A Randomized Controlled Trial by Eric Folkins, Sidharth Sahni, John Ryan, Stacey Wooden, Gina Bushby, Christian Radzinski

“… # Study Design Randomized Trial # Methods Twenty healthy females performed pre-and-post isokinetic (60 degrees/second) concentric/eccentric testing of the elbow flexors, shoulder external rotators, and hip abductors. Participants were randomly assigned to a four-week independent low repetitions/heavy resistance strengthening program performed with either elastic bands or isotonic exercises…”
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Assessment of upper respiratory and gut bacterial microbiomes during COVID-19 infection in adults: potential aerodigestive transmission by Hafez Al-Momani, Andrew Nelson, Hadeel Al Balawi, Dua’a Al Balawi, Iman Aolymat, Ashraf I. Khasawneh, Hala Tabl, Ayman Alsheikh, AbdelRahman M. Zueter, Jeffrey Pearson, Christopher Ward

“…This research explored the relationship between the microbiomes of the upper respiratory and GI tracts in patients with COVID-19 and examined Extraesophageal reflux (EOR), a mechanism which could contribute to dysregulated communication between the GI and respiratory tract (as identified in COVID-19). 97 patients with a laboratory diagnosis of COVID-19 infection, and 50 age-matched controls were recruited and stool, saliva and sputum were obtained from each participant. ELISA Pepsin tests and Reflux Symptom Index scores (RSI) were conducted for EOR assessment. …”
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The FIT FIRST 10 dose-response study: evaluation of implementation outcomes by Sofie Koch, Sofie Koch, Caroline Eckert, Nikos Ntoumanis, Nikos Ntoumanis, Nikos Ntoumanis, Cecilie Thøgersen-Ntoumani, Cecilie Thøgersen-Ntoumani, Cecilie Thøgersen-Ntoumani, Chiara Cimenti, Chiara Cimenti, Malte Nejst Larsen, Peter Krustrup, Peter Krustrup, Lars Breum Skov Christiansen, Lars Breum Skov Christiansen

“…Data were collected from teachers via logbooks documenting implementation fidelity, and an online questionnaire assessing program acceptability, appropriateness, and feasibility, and teachers' capability, opportunity, and motivation for implementing the FF10 program.ResultsA total of 18 intervention schools with 36 classes participated in this study. Program fidelity was high in both intervention groups (2.8 and 2.0 session/week for full and half-dose, respectively). …”
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Peri-implant soft tissue conditioning of immediate posterior implants by CAD-CAM socket sealing abutments: a randomized clinical trial by Mai Mohamed Elgendi, Iman Salah Eldin Hamdy, Hanaa Ibraheem Sallam

“…Purpose To clinically evaluate the peri-implant soft tissue profile of single posterior implant retained restorations and to assess patient related outcomes of the implant restorations that were conditioned immediately by CAD-CAM socket sealing abutments (SSA) versus those conditioned by Titanium (Ti) standard healing abutments (SHA). Methods Twenty participants received twenty-two single maxillary immediate implants after flapless minimally invasive tooth extraction and 3D guided implant placement in the posterior area (premolar and molar) and allocated randomly into two groups (n = 11), the intervention group: patients received PEEK SSA and the control group: the patients received Ti SHA. …”
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Bone Mineral Density, TBS, and Body Composition Indexes in Ukrainian Men with Parkinson’s Disease by Vladyslav Povoroznyuk, Maryna Bystrytska, Nataliia Grygorieva, Iryna Karaban, Nina Karasevich

“…Disease duration was at least 5 years; all PD participants were at levodopa therapy. BMD of lumbar spine, femoral neck, total femur, radius, and total body and TBS Ll−L4 were measured using the DXA method. …”
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Factors protecting against progression of myopia in school students exposed to societal change in Vietnam: a 3-year cohort study by Kyoko Ohno-Matsui, Keiko Nakamura, Kaoruko Seino, Xuan Minh Tri Tran, Hoang Thuy Linh Nguyen, Thao Vi Tran, Tae Igarashi-Yokoi, Thang Van Vo

“…Objectives To elucidate the incidence of myopia, progression of refractive error, axial length (AL) elongation and factors associated with myopia in secondary school students in Vietnam.Design Prospective cohort study.Settings Hue Healthy Adolescent Cohort Study, Hue City, Vietnam.Participants 3-year longitudinal data were available for 355 secondary school students (mean age 11.60±0.36, 46.8% girls). …”
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Additive impact of metabolic syndrome and sarcopenia on all-cause and cause-specific mortality: an analysis of NHANES by Meng Zhang, Qing-Yue Zeng, Linli Zhuang

“…Mortality data were obtained from the National Death Index up to December 2019.ResultsAmong the 21,962 participants, 13,517 (61.5%) had neither MetS nor SP(MetS-/SP-), 5,407 (24.6%) had MetS only(MetS+/SP-), 2,698 (12.2%) had SP only(MetS-/SP+), and 340 (1.5%) had both MetS and SP(MetS+/SP+). …”
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Optimization Analysis of Advertising Information Resource Allocation in View of the Dynamic Game Model by Jun Han

“…It brings huge profits to operators and advertisers participating in bidding every year. Formulate reasonable allocation rules and payment rules for advertising resources in advertising space sales. …”
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The addition of vitamin E could reduce femoral head penetration of the polyethylene liners by Fanxiao Liu, Ling Gao, Dawei Wang, Qingyu Zhang

“…Results Follow an elaborate search of related databases, 23 studies involving a total of 54,920 participants were deemed eligible for this meta-analysis. …”
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Inequalities in demand satisfied with modern methods of family planning among women aged 15–49 years: a secondary data analysis of Demographic and Health Surveys of six South Asian... by Chandrashekhar T Sreeramareddy, Kiran Acharya, Ishwar Tiwari

“…Objective To estimate educational and wealth inequalities in demand satisfied with modern methods of family planning (mDFPS).Design A secondary data analyses of Demographic and Health Surveys.Setting Six South Asian countries, Afghanistan (2015), Bangladesh (2014), India (2015–2016), Maldives (2016–2017), Nepal (2016) and Pakistan (2017–2018).Participants Women aged 15–49 years. Primary and secondary outcome measures mDFPS was defined as married women aged 15–49 years or their partners, who desired no child, no additional children or to postpone the next pregnancy and who are currently using any modern contraceptive method. …”
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Impact of scaling up of kangaroo mother care on neonatal mortality among babies born with birth weight by Tinku Thomas, Arin Kar, Krishnamurthy Jayanna, Prem Mony, Suman P N Rao, Maryann Washington, Prabhu Deva Gowda, Swaroop Narayana, Shashidhar Rao, Mohan Harnahalli Lakkappa

“…Objective To assess the impact of scaling up of kangaroo mother care (KMC) on neonatal mortality among babies born with birth weight <2000 g across an entire district in southern India.Design, setting and participants Within an implementation research setting, analysis of a prospective birth cohort of babies with birth weight <2000 g born during March–December 2018 in Koppal district of Karnataka state, India, to estimate the incidence, risk and HRs of neonatal mortality associated with KMC.Intervention Initiation and maintenance of KMC.Outcome measures Neonatal mortality.Results Among 23 667 live births, 1152 (4.9%) had birth weight <2000 g; the birth weight was <1500 g in 24% and <1000 g in 4%. …”
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Seroprevalence and Associated Risk Factors of Infectious Bovine Rhinotracheitis (IBR) and Animal Owners’ Knowledge, Attitude and Practice (KAP) Towards the Disease in Selected Dist... by Abdisa Mitiku Danu, Abriham Kebede Deresa, Chala Guyassa Dinagde

“…However, 92% of the participants were not informed about the level of knowledge and attitude regarding particular diseases such as IBR. …”
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Condom use among women of reproductive age (18–49 years) in Puerto Rico during the 2016 Zika virus outbreak: secondary analysis of data from a cross-sectional, population-based, ce... by Carrie K Shapiro-Mendoza, Margaret Christine Snead, Karen T Chang, Ruby A Serrano Rodriguez, Connie Bish, Sascha R Ellington

“…We estimated the prevalence of condom use and associated factors among women at risk for unintended pregnancy in Puerto Rico during the 2016 ZIKV outbreak.Design Secondary analysis of a cross-sectional, population-based, cell-phone survey.Setting and participants Women, 18–49 years, living in Puerto Rico during July–November 2016. …”
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Cultural revitalization for tourism development from an Indigenous perspective: the case of Ta Oi people, A Luoi District, Thua Thien Hue province, Vietnam by Thu-Suong Thi Nguyen, Diem-Huong Thi Phan, Diem-Huong Thi Phan, Diem-Hang Le Doan, Diem-Hang Le Doan, Minh-Ngoc Thi Chau, Thanh-Thuy Thi (Jessica) Doan, Thanh-Thuy Thi (Jessica) Doan

“…This study, grounded in constructivist grounded theory, emphasizes the importance of conducting research from the local perspective to maintain authenticity in cultural preservation and to balance the interests of local people, tourists, and stakeholders.MethodsThe qualitative research method employed included fieldwork and focus group discussions conducted in A Luoi district, Thua Thien Hue province, Vietnam. Fieldwork and participation observations allow to capture information about the research area as well as the experiences and behaviors of the local community. …”
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Predictors of Colorectal Cancer Screening and Screening Modalities among Patients seen at Federally Qualified Health Centers Funded by the United States Health Resources and Servic... by Megan R.M. Aaronson, Nadereh Pourat, Connie Lu, Jayraan Badiee, Helen Yu-Lefler, Benjamin Picillo, Hank Hoang, Folasade P. May

“…We aimed to understand how patient-level factors influence CRC screening participation and screening modality choice in this setting. …”
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Does Health System Responsiveness Differ between Insured and Uninsured Outpatients in Primary Health Care Facilities in Asagirt District, Ethiopia? A Cross-Sectional Study by Wubshet Debebe Negash, Asmamaw Atnafu, Desale Bihonegn Asmamaw, Chalie Tadie Tsehay

“…The study sampled 423 participants using a systematic random sampling technique, and the data was collected with structured and pretested questionnaires administered by interviewers. …”
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Longitudinal impact of cross-clamp duration on postoperative sleep disturbance and quality of life in elderly cardiac surgery patients: a secondary analysis of the MINDDS trial by Grace E. Namirembe, Jamie Sparling, Alexis Novak, Ariel Mueller, Julia Bertsch, Kwame Wiredu, Jason Z. Qu, M. Brandon Westover, Timothy T. Houle, Oluwaseun Akeju

“…ObjectivesThis study aimed to assess the enduring impact of cross-clamp duration on postoperative sleep disturbance and functional outcomes (up to 180 days) in cardiac surgery patients.DesignThis is a secondary analysis of data from a randomized, double-blind trial comparing dexmedetomidine to placebo for delirium prevention (Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep).SettingData from patients recruited at a tertiary medical center in Boston, Massachusetts, between March 2017 and February 2022 were analyzed in January 2024.ParticipantsThe study included 394 patients aged ≥60 who underwent cardiac surgery with cardiopulmonary bypass.InterventionsThe primary exposure was cross-clamp time, while secondary exposures included surgical type [isolated coronary artery bypass graft (CABG) or not] and dexmedetomidine randomization.Measurements and main resultsThe primary outcome was sleep quality, assessed using the PROMIS Sleep Disturbance questionnaire at 30, 90, and 180 days postoperatively. …”
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Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism by Eman A. E. Farrag, Mona H. Askar, Zienab Abdallah, Safinaz M. Mahmoud, Eman A. Abdulhai, Eman Abdelrazik, Eman Mohamad El Nashar, Faten Mohammed Alasiri, Asma Nasser Saeed Alqahtani, Mamdouh Eldesoqui, Ali M. Eldib, Alshimaa Magdy

“…The approved treatment for ASD only partially improves the sympoms, but it does not entirely reverse the symptoms. …”
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Twenty-four weeks of combined training in different environments, aquatic and land, in the type 2 diabetes management (Aquatic and Land Exercise for Diabetes -ALED): protocol of a... by Larissa dos Santos Leonel, Ingrid Alessandra Victoria Wolin, Angélica Danielevicz, Mabel Diesel, Marina Isolde Constantini, João Batista de Oliveira Junior, Allana Andrade Souza, Thaís Reichert, João Gabriel Silveira-Rodrigues, Danusa Dias Soares, Marcelo Fernando Ronsoni, Simone Van De Sande Lee, Alex Rafacho, Guilherme Fleury Fina Speretta, Karla Siqueira Lottermann, Josefina Bertoli, Alexandre Pastoris Muller, Aline Mendes Gerage, Cíntia de La Rocha Freitas, Rodrigo Sudatti Delevatti

“…Methods This is a randomized, unicentric, single-blinded, comparator clinical trial with two parallel arms. Participants with T2D, of both sexes, aged at 45 to 80 years old, will be randomized into two groups (aquatic combined training (AQUA) and dry-land combined training (LAND)), both performing combined aerobic and resistance training three times a week on alternate days for 24 weeks. …”
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