Association of outpatient use of renin–angiotensin–aldosterone system blockers on outcomes of acute respiratory illness during the COVID-19 pandemic: a cohort study by Molly Moore Jeffery, Lucas Oliveira J e Silva, Fernanda Bellolio, Nathan W Cummins, Timothy M Dempsey, Vesna D Garovic, Andrew Limper

“…Objectives Evaluate the associations between patients taking ACE inhibitors and angiotensin receptor blockers (ARBs) and their clinical outcomes after an acute viral respiratory illness (AVRI) due to COVID-19.Design Retrospective cohort.Setting The USA; 2017–2018 influenza season, 2018–2019 influenza season, and 2019–2020 influenza/COVID-19 season.Participants People with hypertension (HTN) taking an ACEi, ARB or other HTN medications, and experiencing AVRI.Main outcome measures Change in hospital admission, intensive care unit (ICU) or coronary care unit (CCU), acute respiratory distress (ARD), ARD syndrome (ARDS) and all-cause mortality, comparing COVID-19 to pre-COVID-19 influenza seasons.Results The cohort included 1 059 474 episodes of AVRI (653 797 filled an ACEi or ARB, and 405 677 other HTN medications). 58.6% were women and 72.9% with age ≥65. …”
Get full text

A mixed methods exploration of self-presentation, authenticity, and role model function on Instagram: perspectives from female influencers in Germany by Daniel Zimmermann, Colleen Schneider, Kai Kaspar

“…Quantitative data was examined via inter-correlation matrix and ANOVA, and qualitative data was analyzed via an established approach for qualitative content analysis.ResultsInfluencers pursue mostly self-realization (50% of participants gave at least one related answer) and commercial goals (50%). …”
Get full text

Association between chiropractic spinal manipulative therapy and benzodiazepine prescription in patients with radicular low back pain: a retrospective cohort study using real-world... by Jeffery A Dusek, Robert James Trager, Zachary A Cupler, Kayla J DeLano, Jaime A Perez

“…We hypothesise that utilisation of CSMT for newly diagnosed rLBP is associated with reduced odds of benzodiazepine prescription through 12 months’ follow-up.Design Retrospective cohort study.Setting National, multicentre 73-million-patient electronic health records-based network (TriNetX) in the USA, queried on 30 July 2021, yielding data from 2003 to the date of query.Participants Adults aged 18–49 with an index diagnosis of rLBP were included. …”
Get full text

Functional and effective EEG connectivity patterns in Alzheimer’s disease and mild cognitive impairment: a systematic review by Elizabeth R. Paitel, Christian B. D. Otteman, Mary C. Polking, Henry J. Licht, Kristy A. Nielson, Kristy A. Nielson

“…Of 1,344 initial matches, 124 articles were ultimately included in the systematic review.ResultsThe included studies primarily analyzed coherence, phase-locked, and graph theory metrics. …”
Get full text

Prevalence and associated factors of parental refusal rates for routine immunisation: a cross-sectional study in Peshawar, Khyber Pakhtunkhwa, Pakistan-2024 by Muhammad Hakim, Farhad Ali, Zala, Aslam Pervaiz, Saima Afaq, Zia ul Haq

“…Results Among 340 participants, 22% (n = 74) refused vaccines for their children. …”
Get full text

Qualitative Insights on Barriers to Receiving a Second Dose of Measles-Containing Vaccine (MCV2), Oromia Region of Ethiopia by Kalkidan Solomon, Brooke N. Aksnes, Abyot Bekele Woyessa, Chala Gari Sadi, Almea M. Matanock, Monica P. Shah, Paulos Samuel, Bekana Tolera, Birhanu Kenate, Abebe Bekele, Tesfaye Deti, Getachew Wako, Amsalu Shiferaw, Yohannes Lakew Tefera, Melkamu Ayalew Kokebie, Tatek Bogale Anbessie, Habtamu Teklie Wubie, Aaron Wallace, Ciara E. Sugerman, Mirgissa Kaba

“…Experiences surrounding barriers to MCV2 uptake were discussed via focus group discussions (FGDs) and in-depth interviews (IDIs) with caregivers of children 12–23 and 24–36 months and key informant interviews (KIIs) with HCWs who administer vaccines and with community leaders. Participants were recruited via snowball sampling. Recorded data were transcribed, translated to English, and analyzed using ATLAS.ti v.09. …”
Get full text

Fenótipo clínico da obesidade abdominal e dinapenia: Estudo Longitudinal da Saúde dos Idosos Brasileiros (ELSI-Brasil) by Tatiane Melo de Oliveira, Pricilla de Almeida Moreira, Marília Santos dos Anjos, Daniela de Assumpção, Ligiana Pires Corona

“…No modelo ajustado, foram significativas as associações com tabagismo (0,7; IC95%: 0,5-0,9), consumo de álcool (0,7; IC95%: 0,5-0,9), prática de atividade física (0,6; IC95%: 0,5-0,8), autoavaliação da saúde ruim (1,7; IC95%: 1,4-2,2), multimorbidade (1,3; IC95%: 1,1-1,6), e regiões de residência. …”
Get full text

Adverse birth outcome and associated factors among mothers with antepartum hemorrhage in public hospitals Tigray, northern Ethiopia, 2020 by Tomas Amare Abraha, Gebremedhin Kinfe Gebremariam, Berhane Teklay Asfaha, Tensay Kahsay Weldegebreal, Desta Hailu Aregawi

“…A simple random sampling technique was used to select hospitals and charts of study participants. A Pretested check list was used to collect data. …”
Get full text

Risk Communication and Community Engagement (RCCE) implementations to control cholera outbreak in Oromia region, Ethiopia by Dabesa Gobena, Esayas Kebede Gudina, Getahun Fetensa, Tizta Tilahun Degfie, Tessema Debela, Afework Tamiru, Zenebu Begna Bayissa, Dereje Diriba, Tarekegn Sarbessa, Daniel Bekele, Natinel Teferi, Achalu Layesa, Abate Zewdie, Dawit Worku Ayele, Meron Debebe Mersha, Chala Bafikadu, Senahara Korsa Wake, Lemi Abebe, Tesfaye Kebebew, Tefera Goshu, Birhanu Kenate, Yadeta Dessie, Zeleke Mekonnen

“…Results Only 53% (223) of participants had received health information on cholera of whom 22.8% (96) had material for Social Behaviour Change (SBC) in the local language (Afan Oromo). …”
Get full text

Confounding Risk Factors in Developing Type 1 Diabetes Mellitus among Children and Adolescents at Sulaimani Chronic Diabetes Health Center by Pary Mohammad Azize, Chia H. Sadiq

“…The majority of age at diagnosis was between (5-8) years old, which is 35.3% and their food habit was normal diet, which is 73.5%, while the Sugar diet and Fatty diet were 25.9% and 0.6%y respectively. Most of the participants, 19.4% of  family history was Type 2 diabetes, which was the first rank of the family history and majority of them were Kurdish in nationality. …”
Get full text

Assessment of Risk Factors of Chronic Kidney Disease among Patients Attending Medical City Complex by Nabaa Wisam Sabri, Buthaina Ateyah Rashid, Raheem Saber Shwiehk, Azad H. Mahdy

“…The study was conducted in hospitals of the medical city complex (Baghdad Teaching Hospital, Nursing Home Private Hospital, Ghazy Al-Hariri Hospital for Surgical Specialist, and kidney diseases and Transplant Center) in Baghdad, Iraq, and was designed as a case-control. There were 300 participants (150 cases and 150 controls). Data was collected over five months. …”
Get full text

Hospitalisation rates for epilepsy, asthma and insulin-dependent diabetes in 796 190 school-aged children and young people with and without intellectual disabilities: a record-link... by Angela Henderson, Sally-Ann Cooper, Craig Melville, Michael Fleming, Gillian S Smith, Jill Pell, Deborah Cairns

“…Scotland’s Pupil Census, 2008–2013, was used to identify pupils with and without intellectual disabilities and was linked with the Prescribing Information Service to identify pupils with epilepsy, asthma and insulin-dependent diabetes, and the Scottish Morbidity Records-01 to identify hospital admissions.Setting The general child population of Scotland.Participants School pupils aged 4–19 years; 18 278 with intellectual disabilities and 777 912 without intellectual disabilities.Outcomes Overall, emergency and non-emergency hospitalisations for epilepsy, asthma and/or diabetes; and length of stay.Results Epilepsy and asthma were more prevalent in pupils with intellectual disabilities (8.8% and 8.9%, respectively, compared with 0.8% and 6.9% among pupils without intellectual disabilities, p<0.001), whereas insulin-dependent diabetes was not (0.5% prevalence). …”
Get full text

Dynamic selectout and voting-based federated learning for enhanced medical image analysis by Saeed Iqbal, Adnan N Qureshi, Musaed Alhussein, Khursheed Aurangzeb, Atif Mahmood, Saaidal Razalli Bin Azzuhri

“…Nevertheless, FL faces difficulties with agent/client participation, model performance, and the heterogeneous nature of networked data sources when it comes to distributed healthcare systems. …”
Get full text

E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence. by Alicia Avenhaus, Milica Velimirović, Julia Bulkescher, Martin Scheffner, Felix Hoppe-Seyler, Karin Hoppe-Seyler

“…Thus, although the downregulation of either E6 or E6AP expression also acts partially pro-apoptotic, HPV-positive cancer cells surviving E6 repression proliferate further, whereas they become irreversibly growth-arrested upon E6AP repression. …”
Get full text

L'effet du statut social sur la flexibilité alimentaire des singes magots (Macaca sylvanus) by Ester Orient Pérez, Nerea Amezcua Valmala, Federico Guillén Salazar, Fernando Colmenares

“…Ce travail a été financé partiellement par El Ministerio Español de Economía y Competitividad (PS12011-29016-C02-02) et Le Programme Eurodyssée (Région de Poitou-Charentes et Comunidad Valenciana).…”
Get full text

Gender-based Morphometric Analysis of the Human Orbital Aperture Profile using 3D Reconstruction Computed Tomography: A Cross-sectional Retrospective Study by Muhammad Omer Afzal Bhatti, Mujeeb Ur Rehman Parrey, Muhammad Ikram Ali, Allah Rakhyo Shoro, Abdulkrem Ahmed Alenazi, Rayan Alhumaidi Alruwaili

“…Results: A total of 100 participants were included in the study, with the majority being females (52%). …”
Get full text

Analysis of Calcaneal Bone Mineral Density (cBMD) in Healthy College Students by Jason E. Bennett, Tricia M. Austin, Ann M. Hayes, Mark F. Reinking

“… # Results One hundred three HCS (82 female, 21 male; age 21.9 ± 1.13) consented to participate. The composite score for work, leisure, and sport activity ranged from 5.6 to 11.1 (7.9 ± 1.1) for HCS subjects. …”
Get full text

Narratives of change: how climate change narratives have evolved since the 1970s by Zarina Kulaeva

“…By exploring these climate narratives, we highlight five critical shortcomings related to climate governance: increasing citizen participation through a bottom-up governance model, reforming the environmental subsidy framework, strengthening the science-policy interface, decoupling economic growth from energy dependence and developing innovative technological models beyond traditional green growth approaches. …”
Get full text

Policies on mental health in the workplace during the COVID-19 pandemic: A scoping review. by David Villarreal-Zegarra, C Mahony Reátegui-Rivera, Iselle Sabastizagal-Vela, Miguel Angel Burgos-Flores, Nieves Alejandra Cama-Ttito, Jaime Rosales-Rimache

“…Articles with abstract or full text in English, Spanish, German and Portuguese were also included. …”
Get full text

Exploration of the Immune-Related Signatures and Immune Infiltration Analysis in Melanoma by Ai-lan Li, Yong-mei Zhu, Lai-qiang Gao, Shu-yue Wei, Ming-tao Wang, Qiang Ma, You-you Zheng, Jian-hua Li, Qing-feng Wang

“…Functional enrichment analysis indicated that these immune-related DEGs participated in several areas of immune-related crosstalk, including cytokine-cytokine receptor interactions, JAK–STAT signaling pathway, chemokine signaling pathway, and Th17 cell differentiation pathway. …”
Get full text