A Novel Pyroptosis-Based Prognostic Model Correlated with the Parainflammatory Immune Microenvironment of Pancreatic Cancer by Kong-kong Wei, Zhi-xing Du, Jun-ge Deng, Jin-wei Yang, Hao Chen

“…KRAS and TP53 mutations participated in different inflammatory pathways and played different prognostic roles between the two risk groups. …”
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Laicos y clericales en las reformas constitucionales de Catamarca (1965-1988) by José Ariza

“…En este artículo observaremos esta dicotomía entre laicos y clericales, transitando por la relación entre partidos políticos e Iglesia católica, que nos posibilitará reconstruir un escenario atravesado por un debate más amplio referido a la modernización de la provincia que impregnó a la norma constitucional; además de desnudar coyunturas de crisis políticas que fueron una constante en las tres décadas posteriores al primer peronismo.…”
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Association of blood manganese and selenium levels with hepatic steatosis among adolescents: a nationwide cross-sectional analysis by Bin You, Bin You, Bin You, Bin You, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen

“…Multivariate logistic regression models were used to assess the associations between blood manganese and selenium levels and hepatic steatosis, while restricted cubic splines (RCS) were employed to examine the dose-response relationships.ResultsThe mean age of the participants was 15.37 years, with 52.22% boy. Higher blood manganese and selenium levels were significantly associated with an increased prevalence of hepatic steatosis. …”
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The impact of sleep interventions combined with enhanced nutritional support on sleep quality, nutritional status, pain management, psychological well-being, and quality of life in... by Gang Wang, Shengjie Pan

“…Methods This randomized controlled trial included 290 postoperative colon cancer patients admitted to the First Affiliated Hospital of Soochow University between May 2021 and May 2023. Participants were randomized into two groups: the intervention group, which received standard care supplemented with sleep and nutritional interventions, and the control group, which received standard care alone. …”
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‘They went for the test together but came back separately’: a constructivist grounded theory perspective on male engagement in antenatal HIV testing in Bamenda, Cameroon by Lily Haritu Foglabenchi, Nancy Manigha Nyahkeh, Heidi Stöckl, Tanya Marchant

“…Results Maternal HIV risk perception was the prominent theme intersecting with couple communication, perceptions on HIV testing outcome, and engagement of male partners by facility staff to influence couple prenatal HIV testing behaviours. Although participants recognised the need for couple HIV testing, individual, interspousal, structural and socio-cultural factors determined uptake of male partner testing. …”
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Trend of Soil-Transmitted Helminths in Ethiopian Children: A Systematic Review and Meta-Analysis (2000-2018) by Getaneh Alemu, Feleke Mekonnen, Mezgebu Nega, Chalachew Muluneh

“…Thirty-eight studies recruiting 16,266 participants were included in the review. The pooled prevalence of intestinal parasites was 52.0% (95% CI: 44.4-59.5). …”
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Psychosocial working conditions and violence prevention climate in German emergency departments – a cross-sectional study by Sonja Reißmann, Mannat Guliani, Tanja Wirth, David A. Groneberg, Volker Harth, Stefanie Mache

“…Methods A cross-sectional online survey was carried out among N = 370 participants, who were doctors or nurses from German EDs. …”
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Hyponatremia is associated with malignant brain edema after mechanical thrombectomy in acute ischemic stroke by Ao Qian, Longyi Zheng, Jia Duan, Lun Li, Wenli Xing, Shuang Tang

“…In addition, mediation analysis revealed that postoperative MBE may partially account for the 90-day mortality/adverse function of patients with hyponatremia (regression coefficients changed by 18.6% and 23.9%, respectively). …”
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Chemical Fingerprints for PM2.5 in the Ambient Air near a Raw Material Storage Site for Iron Ore, Coal, Limestone, and Sinter by Kavita Justus Mutuku, Yen-Yi Lee, Guo-Ping Chang-Chien, Sheng-Lun Lin, Wei-Hsin Chen, Wen-Che Hou

“…Abstract To understand the contributions of a raw material storage site for iron ore, coal, limestone, and sinter to ambient air fine particulate matter (PM2.5), the concentrations and chemical fingerprints for resuspended and ambient air PM2.5 were compared. …”
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Vitamin K‐dependent gamma‐carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGF... by Zheng Wu, Qing Ye, Shan Zhang, Li‐Peng Hu, Xiao‐Qi Wang, Lin‐Li Yao, Lei Zhu, Shu‐Yu Xiao, Zong‐Hao Duan, Xue‐Li Zhang, Shu‐Heng Jiang, Zhi‐Gang Zhang, De‐Jun Liu, Dong‐Xue Li, Xiao‐Mei Yang

“…Abstract Background Vitamin K‐dependent γ‐glutamic acid carboxylation (Gla) proteins are calcium‐binding and membrane‐associated, participating in coagulation, bone turnover, and cancer biology. …”
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Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report by Norny Syafinaz Ab Rahman, Nur Alyaa Anisa Mat Harom, Nor Ilyani Mohamed Nazar

“…Case Presentations: This case report presents two cases involving patients with chronic diseases residing in a rural area of Pahang, Malaysia, who participated in pharmacist-led HMR visits. The first case describes a 62-year-old single Malay female with multiple chronic conditions, including Type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, and bronchial asthma, managed with eight prescribed medications. …”
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Bacteriological Profile of Chronic Suppurative Otitis Media and its Antibiotic Sensitivity Pattern at a Tertiary Care Hospital by Geeta Geeta, Naveen G, Apoorva P, Harish MO, Arathi Nair, Harshitha MC, Kiran Revankar, Girish PB

“…Results Mean age of participants was 33.5 years. 94.1% had the unilateral infection. 94.4% had a tubo-tymphanic type while 5.6% had attico-antral type. 70 (77.8%) samples showed mono-microbial growth, 13 (14.4%) showed poly-microbial growth and 7 (7.8%) samples showed no growth in aerobic culture. …”
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Differential attainment at national selection for higher surgical training: a retrospective cohort study by Amanda Lee, Jennifer Cleland, John Hines, Peter Brennan, Ricky Ellis, Yasin Al-Tawarah

“…The objective of this study was to characterise the relationship between candidate sociodemographic factors and performance at National Selection for HST in the UK.Design A retrospective cohort study.Setting National Selection for HST in the UK.Participants All UK graduates in the UKMED database (https://www.ukmed.ac.uk) who underwent selection for HST from 2012 to 2019.Outcomes and measures Performance at HST Selection for each surgical specialty is measured by assessment of the candidate’s academic portfolio and multiple objective structured clinical examination style stations testing knowledge and skills. …”
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Correlation between Parenting Style by Personality Traits and Mental Health of College Students by Minggui Ge, Xiaomeng Sun, Zhen Huang

“…There is no significant difference in their average scores of the partiality of father or mother between the high-anxiety group and the low-anxiety group. …”
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Profile of non-invasive physical health indicators associated with cognitive performance in Chinese older adults: evidence from the China Health and Retirement Longitudinal Study by Xiyu Wei, Chao Li, Dongyu Liu, Jieyi Chen, Yumeng Ju, Jin Liu, Bangshan Liu, Yan Zhang

“…Methods The present study utilized a three-year longitudinal cohort design, with data from the China Health and Retirement Longitudinal Study (CHARLS). 4,869 participants aged 60–97 years from CHARLS wave 2015 and 2018 who were cognitively and physically healthy were included in analysis. …”
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Treatment and prescribing trends of antihypertensive drugs in 2.7 million UK primary care patients over 31 years: a population-based cohort study by Tibor Schuster, Laurent Azoulay, Julie Rouette, Emily G. McDonald, James M. Brophy

“…Objectives To describe the prescribing trends of antihypertensive drugs in primary care patients and assess the trajectory of antihypertensive drug prescriptions, from first-line to third-line, in patients with hypertension according to changes to the United Kingdom (UK) hypertension management guidelines.Design Population-based cohort study.Setting and participants We used the UK Clinical Practice Research Datalink, an electronic primary care database representative of the UK population. …”
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A comprehensive scoping review of intergenerational dance programmes for cohorts with a generational gap. by Siobhán O'Reilly, Orfhlaith Ní Bhriain, Sarah Dillon, Amanda M Clifford

“…Experiences and social outcomes were the most assessed outcomes, with a lack of studies examining physical outcomes. Participants reported enjoying the programmes stating they felt proud for taking part and looked forward to sessions. …”
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Níveis de dano e de controle do percevejo-verde-da-soja Nezara viridula (Hemiptera: Pentatomidae) em feijão-caupi by Paulo Henrique Silva, Candido Athaide Sobrinho

“…Estudos sobre níveis de danos causados por insetos são importantes para tomada de decisão de controle de pragas nas culturas e implementação de práticas de manejo integrado de pragas. Em culturas como as de soja e feijão-comum, esses níveis já foram estudados e definidos, e o manejo de suas pragas já está estabelecido. …”
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Solving unknown primary cancer with earlier diagnosis - the SUPER-ED trial: study protocol for a stepped-wedge cluster randomised controlled trial to support earlier diagnosis for... by Anna Ugalde, Richard W. Tothill, Stephen Quinn, Hui-Li Wong, Owen Prall, Catherine Mitchell, Nilmini Wickramasinghe, Clare Fedele, Natalie Richards, Elizabeth Todio, Cindy Bryant, Louisa G. Collins, Sarah McLean, Hyun Soo Ko, Tim Akhurst, Christopher Steer, Bo Gao, Mark Wong, Chloe Georgiou, Narayan Karanth, Anna Kuchel, Louise Nott, Shamsudheen Padinharakam, Mark Shackleton, Ian M. Collins, Madhu Singh, Rachel Wong, Zee Wan Wong, Alexis Butler, Tharani Sivakumaran, Penelope Schofield, Linda Mileshkin

“…Secondary outcomes are whether the type of tumour is diagnosed, clinical trial participation, referral to palliative care, patient-reported physical, social and mental health, patient-reported understanding and uncertainty. …”
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Chronic kidney disease progression in patients with previous type 2 diabetes and/or hypertension: a population-based cohort study from primary care in Spain by David Vizcaya, Betlem Salvador-González, Oriol Cunillera-Puértolas, Sílvia Cobo-Guerrero, José Romano-Sánchez, Daniel Bundó-Luque, Ariadna Arbiol-Roca

“…Objectives To evaluate whether between hypertension and type 2 diabetes (T2D)—established drivers of chronic kidney disease (CKD) progression—one might be more strongly associated with CKD progression than the other.Design Cohort study using a primary care database (electronic health records).Setting Primary care in Catalonia, Spain.Participants 438 273 patients with CKD identified from the Information System for Research in Primary Care database in Catalonia (2007–2017) and stratified into four mutually exclusive groups based on the presence/absence of hypertension and/or T2D. …”
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