Transcription Factor FXR Activates DHRS9 to Inhibit the Cell Oxidative Phosphorylation and Suppress Colon Cancer Progression by Jinlai Zhao, Yigang Wang, Yang Wang, Jianchao Gao, Haichao Yang, Xiaotang Wu, Hua Li

“…Moreover, promoting FXR expression in colon cancer cells could partially reverse the biological function changes caused by silencing DHRS9 expression. …”
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Short-term effects of empagliflozin on preventing contrast induced acute kidney injury in patients undergoing percutaneous coronary intervention, a randomised trial by Zeinab Sadat Hosseini, Mohammad Javad Jamili, Behzad Ensan, Ghazaleh Donyadideh, Bahram Shahri, Hamid Eshraghi, Susan Darroudi, Mohsen Moohebati

“…This research conducted a double-blind randomized clinical trial involving 121 patients undergoing PCI referred to Ghaem Hospital, Mashhad, Iran from 2022 to 2023. Participants were randomly assigned to receive empagliflozin (10 mg daily) or a placebo, starting one day before PCI and continuing for two days post-procedure. …”
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Fitting and comparison of calcium-calmodulin kinetic schemes to a common data set using non-linear mixed effects modelling. by Domas Linkevicius, Angus Chadwick, Guido C Faas, Melanie I Stefan, David C Sterratt

“…Our results support two hypotheses: (1) partially bound calmodulin is important in cellular signalling; and (2) calcium binding sites within a calmodulin lobe are kinetically distinct rather than identical. …”
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Association between urinary cobalt exposure and kidney stones in U.S. adult population: results from the National Health and Nutrition Examination Survey by Jun Lu, Dongmei Hong, Qian Wu, Yinghui Xia, Guozhong Chen, Tie Zhou, Cheng Li

“…Moreover, we used propensity score matching (PSM) to exclude the effect of confounding variables.Results After a rigorous enrollment screening process, we included 8518 participants. Logistic regression showed that urinary cadmium (U-Cd) and urinary cobalt (U-Co) concentrations were significantly different in the kidney stone group before PSM (p < 0.001). …”
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Understanding neurocognitive recovery in older adults after total hip arthroplasty—neurocognitive assessment, blood biomarkers and patient experiences: a mixed-methods study by Ulrica Nilsson, Karin Liander, Lina Bergman, Anahita Amirpour, Jeanette Eckerblad, Gabriela Markovic

“…This study aims to address the knowledge gap in postoperative neurocognitive recovery by exploring the relationship between subjective experiences, performance-based measurements, and blood biomarkers.Design Mixed-methods study with a convergent parallel (QUAL+quan) design.Setting and participants The study reports results from 40 older adult patients (52.5% women; mean age 73, SD 6.7) scheduled for total hip arthroplasty at a hospital in Sweden.Outcome measures Neurocognitive performance was assessed using a standardised test battery, neuroinflammation through blood biomarker analysis and postoperative neurocognitive recovery via semistructured interviews and the Swedish Quality of Recovery questionnaire.Results Five patients were classified as having delayed neurocognitive recovery based on performance tests. …”
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Work engagement of psychiatric nurses: a scoping review protocol by Yuichi Kato, Tsuyoshi Mukaihata, Toshiyuki Swa, Hirokazu Fujimoto

“…The inclusion criteria will be based on nurses (participants), work engagement (concept), and psychiatric settings (context) without language or date restrictions. …”
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A Real-Time Human Pose Measurement System for Human-In-The-Loop Dynamic Simulators by Nicola Giulietti, Davide Todesca, Marco Carnevale, Hermes Giberti

“…The system is integrated into a clinical rehabilitation device, a three-degree-of-freedom parallel kinematic machine, to facilitate patient participation in exergames. The proposed human-pose estimation method achieves real-time performance, enabling the motion platform to be controlled dynamically based on the patient&#x2019;s actual standing pose.…”
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Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting by Salvador Figuereo, Sahra Isse Mohamed, Desalegn Takele, Abdulrahman M. Sheikh, Solomon Chane Abera, Ayni Muhiadin Mohamed, Mutaawe Lubogo, Hassan Mukhtar Abukar, Mary Joan Karanja, Sulaiman Bangura, Antoine Abou Fayad, Ali Haji Adam, Abdinasir Yusuf Osman, Sk Md Mamunur Rahman Malik

“…These laboratory and testing enhancements have enabled Somalia to participate in surveillance for priority diseases and detection of outbreaks caused by emerging pathogens. …”
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Implementing a rapid geographic range expansion - the role of behavior changes by Logan, Corina, McCune, Kelsey, LeGrande-Rolls, Christa, Marfori, Zara, Hubbard, Josephine, Lukas, Dieter

“…We found that grackles in the edge population had a higher flexibility variance (measured by reversal learning) and a higher persistence average (they participated in a larger proportion of trials), and that there were no population differences in average levels of flexibility, innovativeness (number of loci solved on a multiaccess box), or exploration (latency to approach a novel environment). …”
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A metodologia da tessitura analítica de mídia como possibilidade na pesquisa de enfermagem by Liciane da Silva Costa Dresch, Fernanda Carlise Mattioni, Cristianne Maria Famer Rocha

“…Conclusões e implicações para a prática a análise de mídia e sua tessitura podem representar uma possibilidade potente de análise de dados em pesquisas na enfermagem, fornecendo ferramentas conceituais e estratégicas para novos olhares e reflexões na contemporaneidade da área da saúde.…”
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Clinical findings of acute necrotizing esophagitis complicated by diabetic ketoacidosis by Yuichiro Iwamoto, Tomohiko Kimura, Takashi Itoh, Shigehito Mori, Taku Sasaki, Mana Ohnishi, Haruka Takenouchi, Hideyuki Iwamoto, Junpei Sanada, Yoshiro Fushimi, Yukino Katakura, Fuminori Tatsumi, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto

“…We compared the clinical parameters and computed tomography (CT) between the groups. The mean age of participants was 57.7 ± 20.4 years, and their mean HbA1c was 11.1 ± 3.3%. …”
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Prediction of the Influential Factors on Eating Behaviors: A Hybrid Model of Structural Equation Modelling-Artificial Neural Networks by Maryam M. Kheirollahpour, Mahmoud M. Danaee, Amir Faisal A. F. Merican, Asma Ahmad A. A. Shariff

“…In the second step, the input and output required for ANN analysis were obtained from SEM analysis and were applied in the neural network model. 340 university students participated in this study. The hybrid model (SEM-ANN) was conducted using multilayer perceptron (MLP) with feed-forward network topology. …”
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The Pollyanna Effect: The role of positive personal and group identity defense mechanisms by T.A. Nestik

“…The results of our empirical research indicate that group identity participates in the processes of emotional self-regulation and mobilization of psychological resources when experiencing an uncontrollable threat, reducing the level of individual and collective anxiety. …”
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Innovative epilepsy management: a combined figure of EEG categorization and medication mechanisms by Mohamed Taha, Douglas R. Nordli, Carol Park, Douglas R. Nordli

“…We present an innovative educational tool that integrates EEG categorization with antiseizure medication mechanisms, designed to enhance clinical decision-making in epilepsy management.MethodsThis study evaluated a cohort of neurology trainees through a pre-test and post-test design. Participants were assessed on their ability to diagnose epilepsy syndromes and select appropriate treatments based on EEG findings before and after exposure to the teaching figure. …”
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Upregulation of PGC-1α Attenuates Oxygen-Glucose Deprivation-Induced Hippocampal Neuronal Injury by Bin Han, Hui Zhao, Xingji Gong, Jinping Sun, Song Chi, Tao Liu, Anmu Xie

“…The further bioinformatics analysis from ChIP-Seq data indicated that PGC-1α may participate in the regulation of apoptosis, autophagy, and mitophagy pathways in HT-22 cells. …”
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Immune checkpoint inhibitor-induced diabetes mellitus: clinical characteristics and risk factors by Mei Zhan, Mei Zhan, Qinran Long, Qinran Long, Jinhan He, Jinhan He, Jinhan He, Litao Huang, Bin Wu, Bin Wu, Haixia Xu, Li Mo, Ting Xu

“…We applied logistic regression to study the associations between clinical characteristics and ICI-DM.ResultsOur study included 8,199 participants who received ICI between October 2014 and June 2023. …”
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Numerical Study on Combustion Behavior of Tuyere and Raceway in Blast Furnace with Oxygen-Rich Blast and Hydrogen Injection by Ruimeng Shi, Yue Pei, Mengmeng Ren, Zheng Xue, Xinqi Li, Heping Liu

“…Because more carbon participates in the raceway reaction with an increase in oxygen enrichment rate from 0% to 10%, the final carbon monoxide fraction in the coke bed increases from 0.29 to 0.40, and the final hydrogen fraction decreases from 0.15 to 0.13. …”
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Additive Manufacturing and Augmented Reality as New Production Technologies in the Aviation Industry by M. G. Yevtodyeva

“….), as well as beginning of serial production of many AM-components and AR-platforms for the aviation industry. The participation of major aircraft manufacturers such as Boeing and Airbus in AM and AR R&amp;D projects, the formation of "new" supply chains, the development of public-private partnerships (e.g. …”
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Plasma Inflammatory Biomarkers Indicative of Aging and Overweight in Brazilian Women by Débora Nonato Miranda de Toledo, Priscilla Vilela dos Santos, Nathalia Sernizon Guimarães, Alessandra de Paula Carli, Patrícia Regina Soares de Souza, Luiza Oliveira Perucci, Caio César de Souza Alves, André Talvani

“…Out of the total study participants, 54 women (mean age 44.9 years) were overweight and presented high plasma levels of CK, CXCL16, IL-33, and leptin. …”
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Gestores intermediários e a ação gerencial: um estudo sobre a percepção de suporte organizacional em uma universidade federal by João Marcio Silva de Pinho, Adriana Ventola Marra

“…Entende-se a gestão como prática social, a partir de um olhar relacional, visto que é permeada por ambiguidades e contradições. …”
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