Clinical course of spinal pain in adolescents: a feasibility study in a chiropractic setting by Steven J Kamper, Christopher G Maher, Mark J Hancock, Simon D French, Lise Hestbæk, Katherine A Pohlman, Michael S Swain, Laura RC Montgomery, Anika Young, Amber Beynon

“…Design Prospective feasibility study.Objectives To inform the design and conduct of a large-scale clinical cohort study investigating adolescents with moderate-to-severe spinal pain.Setting Chiropractic care in Sydney, Australia.Participants Adolescents aged 12–17 years with spinal pain (≥4/10 pain intensity score).Methods Adolescents and chiropractors completed baseline and week-12 follow-up questionnaires, with adolescents reporting pain intensity and recovery weekly via text messages during weeks 1–11. …”
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Unique or not unique? Comparative genetic analysis of bacterial O-antigens from the Oxalobacteraceae family by S. D. Afonnikova, A. S. Komissarov, P. D. Kuchur

“…The outcome can be neutral, harmful or have beneficial effects for participants. Remarkably, these relationships are not static, as they change throughout an organism’s lifetime and on an evolutionary scale. …”
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A descriptive study of smoking, socioeconomic position, and health-related behaviors in urban Colombia by Valentina Guatibonza-García, Sofía Gnecco-González, Agustín Pérez-Londoño, Carolina Betancourt-Villamizar, Carlos O. Mendivil

“…Results The study included 1904 participants (53.9% female, age 47 ± 19 years). The estimated prevalence of smoking was 22.0% (29.0% in males, 15.7% in females), underage smoking was 4.8%. …”
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A Decades-Long Journey of Palmitoylethanolamide (PEA) for Chronic Neuropathic Pain Management: A Comprehensive Narrative Review by Giustino Varrassi, Martina Rekatsina, Matteo Luigi Giuseppe Leoni, Marco Cascella, Gabriele Finco, Salvatore Sardo, Chiara Corno, Domenico Tiso, Vittorio Schweiger, Diego Maria Michele Fornasari, Antonella Paladini

“…One of them (Equisetum-PEA) seems promising. It partially ameliorates the bioavailability and the targeted distribution. …”
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Voluntary Forelimbs Exercise Reduces Immobilization-Induced Mechanical Hyperalgesia in the Rat Hind Paw by Kumiko Ishikawa, Satoshi Oga, Kyo Goto, Junya Sakamoto, Ryo Sasaki, Yuichiro Honda, Hideki Kataoka, Minoru Okita

“…Our results therefore suggest that voluntary forelimb exercise during hind limb immobilization partially reduces immobilization-induced hyperalgesia by suppressing that the plastic changes of the primary sensory nerves that excessively transmit pain and increased responsiveness of nociceptive neurons in the spinal dorsal horn.…”
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Comparison of the efficacy and safety of bupropion versus aripiprazole augmentation in adults with treatment-resistant depression: a nationwide cohort study in South Korea by Dong Yun Lee, Rae Woong Park, Soo Min Jeon

“…The subgroup analysis of participants aged ≥60 years revealed no significant differences in the three outcomes between the two medications. …”
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Incidence of hyperkalemia RAASi and SGLT-2i treatment in individuals with diabetic kidney disease: a systematic review and network meta-analysis by Yahui Yuan, Yahui Yuan, Yahui Yuan, Chun Chen, Yuping Lin, Yehao Luo, Yehao Luo, Yehao Luo, Zhaojun Yang, Zhaojun Yang, Zhaojun Yang, Jingyi Guo, Jingyi Guo, Jingyi Guo, Qiaoyun Liu, Qiaoyun Liu, Qiaoyun Liu, Lu Sun, Guanjie Fan, Guanjie Fan, Guanjie Fan

“…The surface under the cumulative ranking curves (SUCRA) was utilized for ranking purposes.ResultsThe study included 36 trials, encompassing 45,120 participants, comparing various interventions. SGLT-2i (SUCRA = 88.5%) was found to significantly reduce the risk of hyperkalemia. …”
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The relationships between mental health and social media addiction, and between academic burnout and social media addiction among Chinese college students: A network analysis by Tingwei Feng, Buyao Wang, Mingdi Mi, Lei Ren, Lin Wu, Hui Wang, Xufeng Liu, Xiuchao Wang

“…Methods: A cross-sectional study was conducted with undergraduates and doctoral students from Air Force Medical University. Participants (n = 432) completed self-report scales, including the Depression Anxiety and Stress Scale, Academic Burnout Inventory, and Bergen Social Media Addiction Scale. …”
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The role of polymorphic variants of arginase genes (<i>ARG1, ARG2</i>) involved in beta-2-agonist metabolism in the development and course of asthma by O. N. Savelieva, A. S. Karunas, Yu. Yu. Fedorova, R. R. Murzina, A. N. Savelieva, R. F. Gatiyatullin, E. I. Etkina, E. K. Khusnutdinova

“…In Russians and Tatars receiving glucocorticoid monotherapy or combination therapy, the association of the rs17249437*T allele and rs17249437*TT genotype of the ARG2 gene with a partially controlled and uncontrolled course of asthma was shown.…”
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Galectin-1-Dependent Mitochondria Apoptosis Plays an Essential Role in the Potential Protein Targets of DBDCT-Induced Hepatotoxicity as Revealed by Quantitative Proteomic Analyses by Jiayu Song, Yuan Ren, Lihua Liu, Yixin Wang, Chuandao Shi, Xiaoqing Ji, Yunlan Li, Qingshan Li

“…Correspondingly, NAC (inhibitor of ROS), PDTC (inhibitor of NF-κB), EGF (ERK1/2 activator), and OTX008 (inhibitor of Gal-1) were found to reverse and abolish the DBDCT-associated cytotoxicity partially. In conclusion, Gal-1 might be the potential target for toxicity and biological activity. …”
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Development of an algorithm impacting COPD care through personalized nutrition and IoT-based monitoring by Prachi Sharma, Mihir Gharia, Devina Aswal, Vishva Trivedi, Bhavnita Soni, Prerna Soni, Devesh Joshi, Dhvni Lalan, Vrushali Athavale, Irfan Shaikh, Koshy Jacob

“…The distance covered during the 6MWT also improved from 420 to 568 m (p = 0.0019). The participation of 10 COPD patients in surveys yielded an overall CSAT score of 85%, indicating a high level of satisfaction with the MyTatva app. …”
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Changes in urinary concentrations of contemporary and emerging chemicals in commerce during the COVID-19 pandemic: Insights from the Environmental influences on Child Health Outcom... by Megan E Romano, Jessie P Buckley, Xiuhong Li, Julie B Herbstman, Kurunthachalam Kannan, Sunmi Lee, Susan L Schantz, Leo Trasande, Margaret R Karagas, Frederica Perera, ECHO Cohort Consortium

“…Drawing from three racially, ethnically, and socioeconomically diverse ECHO cohorts, we assessed key differences in urinary chemical concentrations related to environmental exposures through food packaging, use of disinfectants, personal care products and air pollutants using repeated urine samples in a subset of 47 participants, who contributed a urine sample prior to the pandemic (between October 2018 and February 2020) and a subsequent urine sample after the pandemic began (between March 2020 and April 2021). …”
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Identification of novel RIPK4 variants in a Chinese patient with Arthrogryposis Multiplex Congenita (AMC) by Yi-Lei Lu, Meng-wei Liu, Jie-Yuan Jin, Ding Pan

“…Trial registration The research protocol received approval from the Ethics Review Committee of Xiangya Hospital of Central South University in China (approval number: 202103427), registered in March 2021, with all participants providing duly signed informed consent forms.…”
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Adoption of the Polish Bariatric and Metabolic Surgery Care Standards: a nationwide survey by Mateusz J. Świerz, Karolina Majdak, Andrzej Budzyński, Wiesław Tarnowski, Piotr Major, Małgorzata M. Bala

“…Significant predictors of better compliance included the number of surgeons performing MBS and participation in the KOS-BAR program (a program of complex specialist care over patient undergoing bariatric surgery). …”
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Nurses Practice of Hand Hygiene in Hiwot Fana Specialized University Hospital, Harari Regional State, Eastern Ethiopia: Observational Study by Nefsu Awoke, Biftu Geda, Aseb Arba, Tiwabwork Tekalign, Kebreab Paulos

“…A total of 110 study participants were observed who gave a response rate of 94.8%. …”
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Reflexões sobre a contemporaneidade by Nadiá Paulo Ferreira

“…Segundo ela, estariámos, ainda, vivendo a ditadura das práticas médicas, o imperialismo das técnicas e dos números. …”
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In-vitro acaricidal activity of peganum harmala and glaucium flavum alkaloid against rhipicephalus sp. of dog by Rosa Kebbi, Omar Besseboua, Mohamed Nait-Mouloud, Abdelhanine Ayad

“…Visually hatching of the eggs was completely blocked only by G. flavum with 50 mg/ml; however, other extracts of both plants were partially able to block the hatching. The oviposition and reproductive rate of both plants were concentration dependent in both plants and significantly different (p<0.05) compared to negative control. …”
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Interleukin-18 Expression Increases in the Aorta and Plasma of Patients with Acute Aortic Dissection by Haiying Hu, Guangtai Zhang, Huanli Hu, Wenjing Liu, Jixiang Liu, Shuanli Xin, Xiufeng Zhao, Liying Han, Liping Duan, Xinshun Huang, Chao Chang

“…Conclusion. IL-18 may participate in AD by regulating macrophage differentiation and macrophage-induced SMC apoptosis.…”
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Spinal Cord Lesion: Effects of and Perspectives for Treatment by V. Dietz

“…Based on observations of the locomotor capacity of the spinal cat, recent studies have indicated that spinal locomotor centers can be activated and trained in patients with complete or incomplete paraplegia when the body is partially unloaded. However, the level of electromyographic activity in the gastrocnemius (the main antigravity muscle during gait) is considerably lower in the patients compared to healthy subjects. …”
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Patients’ and physiotherapists’ perspectives on implementing a tailored stratified treatment approach for low back pain in Nigeria: a qualitative study by Kay Stevenson, Mishael Adje, Jost Steinhäuser, Chidozie Emmanuel Mbada, Sven Karstens

“…The interviews were recorded, transcribed and analysed following grounded theory methodology.Results Twelve physiotherapists and 13 patients with LBP participated in the study (11 female, mean age 42.8 (SD 11.47) years). …”
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