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27601
Will things feel better in the morning? A time-of-day analysis of mental health and wellbeing from nearly 1 million observations
Published 2025-02-01“…But although broader mental health and well-being also vary over months and weeks, it is unclear whether there are diurnal changes in how people experience and report their mental health.Objective To assess time-of-day association with depression, anxiety, well-being and loneliness.Methods The study analysed data from 49 218 adults drawn from the University College London COVID-19 Social Study, which gathered detailed repeated measurements from the same participants across time over a 2-year period (March 2020–March 2022, 18.5 observation per person). …”
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27602
Insulin Resistance Increases MRI-Estimated Pancreatic Fat in Nonalcoholic Fatty Liver Disease and Normal Controls
Published 2013-01-01“…We found a strong correlation between hepatic and pancreatic MRI-PDFF (Spearman correlation, P = 0.57, P value <0.001). Participants with increased insulin resistance determined by homeostatic-model-of-insulin-resistance (HOMA-IR) greater than 2.5 had higher pancreatic (7.3% versus 4.5%, P value =0.015) and liver (13.5% versus 4.0%, P value <0.001) MRI-PDFF. …”
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27603
Comparative legal analysis of the expertise in court under the criminal law of Ukraine and CIS countries
Published 2021-12-01“…The presiding judge at the request of the parties should provide an opportunity to study in detail the conclusion of the expertise conducted in court.…”
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27604
Diagnosis of the mechanisms of different types of discordances between phylogenies inferred from nuclear and mitochondrial markers
Published 2020-07-01“…The mechanisms that g nerated extremely high biodiversity in the ancient lakes have not been sufficiently studied and remain only partially known. Sequences of environmental changes in highly complex ecosystems such as Lake Baikal, may induce sophisticated combinations of microevolutionary processes. …”
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27605
A hypothesis about interrelations of epigenetic factors and transposable elements in memory formation
Published 2024-09-01“…Also, a number of studies on different animals have revealed the preservation of long-term memory without the participation of synaptic plasticity. The data obtained suggest that transposons, which are genome sensors highly sensitive to various environmental and internal influences, form memory at the nuclear coding level. …”
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27606
EUROPEAN UNION AFTER THE CRISIS: DECLIN OR RENAISSANCE?
Published 2013-08-01“…The headline targets and indicators of the "Europe 2020" strategy will be implemented only partially. Modernization process will be hampered by the lack of funding for basic science, which occurred due to the end of the "cold war", as well as social factors whose role in the economic progress had been previously underestimated. …”
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27607
O-GlcNAc transferase mediates O-GlcNAcylation of NLRP3 regulates pyroptosis in spinal cord injury
Published 2025-03-01“…Discussion and conclusion: This study preliminarily proved that the mechanism of OGT mediated O-GlcNAcylation of NLRP3 participates in the action of pyroptosis in SCI. Targeting OGT and NLRP3 may be novel therapy method in SCI.…”
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27608
Peripheral blood miRNAs are associated with airflow below threshold in children with asthma
Published 2025-01-01“…Results We found 1 upregulated and 1 downregulated miRNA in participants with airflow below the threshold compared to those above it. …”
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27609
Repositórios digitais educativos institucionais: uma abordagem colaborativa para a educação contemporânea
Published 2024-12-01“…Esta metodologia permite não apenas a análise das necessidades e desafios técnicos, mas também proporciona insumos para o desenvolvimento de soluções educativas práticas e eficientes. Os resultados obtidos contribuem para a compreensão dos requisitos necessários à implementação bem-sucedida de RDEIs e para o estabelecimento de diretrizes na formação de equipes técnicas especializadas. …”
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27610
Exploring Virtual Reality and Exercise Simulator Interventions in Patients With Attention Deficit Hyperactivity Disorder: Comprehensive Literature Review
Published 2025-01-01“…ConclusionsThis scoping review contributes to the ongoing research on enhancing interventions to support individuals with ADHD. It advocates for participant-centric approaches that aim to optimize both cognitive and motor outcomes while prioritizing the enhancement of user experiences. …”
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27611
Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells
Published 2016-01-01“…These results indicate Oncostatin M as a potent inducer of IL-33 in mouse lung epithelial cells and suggest that an OSM/IL-33 axis may participate in innate immunity and inflammatory conditions in lung.…”
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27612
Validity, Reliability, and Efficiency of a Standard Goniometer, Medical Inclinometer, and Builder’s Inclinometer
Published 2023-08-01“… # Methods Fifty participants with no current shoulder, elbow, or forearm pain limiting movement were assessed by a single tester. …”
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27613
Economic and environmental performance analysis of Polish energy companies
Published 2019-08-01“…Polish energy companies, which mainly use coal in the energy production process, are particularly worried about the potential negative consequences associated with the implementation of new CO<sub>2</sub> emission reduction targets and their participation in the European Union Emissions Trading System. …”
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27614
Searching for effective strategies to reach boys and young men; a mixed-methods study protocol for youth clinics in Sweden
Published 2024-10-01“…This is crucial for (1) developing gender-sensitive services and service delivery models that effectively promote young men’s SRH; (2) informing future young men’s health policies ensuring that their unique SRH concerns are addressed; and (3) improving young men’s participation in SRH provision. This will ultimately foster a culture of shared responsibilities and advance gender equality.…”
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27615
The Sound Sensitivity Symptoms Questionnaire Version 2.0 (SSSQ2) as a Screening Tool for Assessment of Hyperacusis, Misophonia and Noise Sensitivity: Factor Analysis, Validity, Rel...
Published 2024-12-01“…The average age of the participants was 36.5 years (range 18 to 86 years). <b>Results:</b> Confirmatory factor analysis showed that the SSSQ2 is a one-factor questionnaire. …”
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27616
Effect of icatibant on sweating-induced dermal pain
Published 2025-02-01“…This study aimed to evaluate the analgesic effect of icatibant, a bradykinin B2 receptor antagonist, for the dermal pain induced by sweating stimuli and explored the role of bradykinin in its pathomechanism.MethodsThis single-blind, randomized, crossover study enrolled adult patients who had experienced severe sweating-induced dermal pain. Participants randomly received icatibant (30 mg) or placebo on Day 1 and vice versa on Day 2. …”
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27617
Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells
Published 2025-01-01“…The results showed that CPV VP2 protein participated mainly in cell metabolism, cell biosynthesis, protein folding and various signal transduction processes. …”
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27618
Nomophobia and University Business Students’ Burnout in Online Learning: Mediating effect of Fear of Missing Out
Published 2024-10-01“…The study found a significant relationship between Nomophobia, FoMO, and SBO, where Nomophobia affects FoMO and SBO, while FoMO notably impacts SBO's academic efficacy. FoMO partially mediates the Nomophobia-SBO relationship. …”
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27619
Long non-coding RNAs modulate glutathione metabolism gene expression and tolerance to Pb stress in root tissue of endophyte-infected rice seedling
Published 2025-02-01“…DEmRNAs in ceRNA network were mainly participated in carbohydrate metabolic process, peroxidase activity and phenylpropanoid biosynthesis. …”
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27620
Model for End-Stage Liver Disease Score Predicts the Mortality of Patients with Coronary Heart Disease Who Underwent Percutaneous Coronary Intervention
Published 2021-01-01“…A retrospective cohort study involved 5373 patients with coronary heart disease after PCI was conducted from January 2008 to December 2016. Participants were classified to four groups according to the MELD score by quartiles. …”
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