Early assessment of IL8 and PD1+ Treg predicts response and guides treatment monitoring in cemiplimab-treated cutaneous squamous cell carcinoma by Teresa Troiani, Fabiana Napolitano, Luigi Formisano, Roberto Bianco, Daniela Russo, Daniela Esposito, Giuseppe Ercolano, Angela Ianaro, Alberto Servetto, Daniela Claudia Maresca, Marcella Scala, Annarita Amato, Stefania Belli, Claudia Maria Ascione, Angela Vallefuoco, Giovanna Attanasio, Fabio Somma, Silvia Varricchio, Massimo Mascolo, Claudia Costa, Alessia Villani, Massimiliano Scalvenzi, Gianfranco Orlandino

“…Additionally, our data suggest that IL8 levels in peripheral blood offer promising avenues for personalized treatment selection and response assessment in patients with cSCC receiving cemiplimab, while PD1+Tregs can be followed longitudinally to monitor response to therapy.…”
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Intestinal Parasite Infection and Its Association with Undernutrition among Early Adolescents in Hawassa University Technology Village, Southern Ethiopia by Amelo Bolka Gujo, Assefa Philipos Kare, Shambel Gussa Shuramo

“…Strengthening nutrition interventions, deworming programs, and health education on personal and environmental hygiene and sanitation are recommended.…”
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Epidemiologic Investigation of Intestinal Parasite Infection and Associated Risk Factors among Primary Schoolchildren in the Manzini and Lubombo Provinces, the Kingdom of Eswatini by Ai-Wen Yin, Yueh-Lun Lee, Sindisiwe Dlamini, Gugu Maphalala, Chien-Wei Liao, Chia-Kwung Fan

“…Present study showed that 27.8% (88/316) of PSC were infected by more than one pathogenic parasite. Personal hygiene like washing hands before a meal has a significant protection effect (OR = 0.32, 95% CI = 0.14–0.75, p=0.009). …”
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Bridging the gap: attitudes and practices toward complementary and alternative medicine among oncology patients and healthcare professionals in Croatia by Ljerka Armano, Vanja Vasiljev, Tomislav Rukavina, Denis Juraga, Aleksandar Racz, Aleksandar Racz, Vanja Tešić, Vanja Tešić, Vanja Tešić

“…Additionally, it explores the influence of sociodemographic factors and personal experiences on these attitudes. A cross-sectional survey was conducted between November 2022 and May 2023 at University Hospital Center Sisters of Mercy, Zagreb, Croatia. …”
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Assessment, Decision, Adaptation, Production, Topical Experts-Integration, Training, and Testing (ADAPT-ITT) Framework to Tailor Evidence-Based Posttraumatic Stress Disorder Treatm... by Cristina M Lopez, Angela D Moreland, Stephanie Amaya, Erin Bisca, Christin Mujica, Tayler Wilson, Nathaniel Baker, Lauren Richey, Allison Ross Eckard, Patricia A Resick, Steven A Safren, Carla Kmett Danielson

“…Despite high rates of PTSD in persons with HIV (PWH) and poor HIV-related health outcomes associated with PTSD, an effective evidence-based treatment for PTSD symptoms in PWH does not exist. …”
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Refinement of a meaning-centered counseling program for Chinese patients with advanced cancer: integrating cultural adaptation and implementation science approaches by Florence Lui, Qingyi Zhang, George Chengxi Bao, Bharat Narang, Ruo Yan Chen, Yunshan Niu, Jennifer Leng, William Breitbart

“…Qualitative analysis yielded 23 inductive codes under the seven EVM domains: (1) Language (3 subcodes), (2) Persons (2 subcodes), (3) Metaphors/Stories (2 subcodes), (4) Methods (8 subcodes), (5) Content (2 subcodes), (6) Goals (4 subcodes), and (7) Concepts (2 subcodes). …”
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Od porodní báby k porodní asistence by Milena Lenderová

“…Current time has again rehabilited the personality of midewife. We can say that the development of obstetrics in the industrial countries reminds a circle: from the monopoly of midewife to the monopoly of medical doctor and from this one back again. …”
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Characterization of diabetic kidney disease in 235 patients: clinical and pathological insights with or without concurrent non-diabetic kidney disease by Mengjie Jiang, Hongyu Chen, Jing Luo, Jinhan Chen, Li Gao, Qin Zhu

“…Additionally, significant discriminative factors including BMI, blood creatinine level, microscopic erythrocyte grade, UIgG/urine creatinine ratio, and serum IgA levels help differentiate DKD from NDKD, thereby enabling personalized treatment approaches. Furthermore, the study highlights the role of RASi as the most commonly used drug in the treatment of both DKD and NDKD, with emerging drugs such as SGLT2 inhibitors showing promising renal protective effects.…”
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Hyponatremia is associated with malignant brain edema after mechanical thrombectomy in acute ischemic stroke by Ao Qian, Longyi Zheng, Jia Duan, Lun Li, Wenli Xing, Shuang Tang

“…The occurrence of MBE was evaluated via computed tomography after MT, and 90-day outcomes were obtained through in-person interviews at the clinic or via telephone. …”
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Dietary Exposure to Aflatoxins in Some Randomly Selected Foods and Cancer Risk Estimations of Cereals Consumed on a Ghanaian Market by Nii Korley Kortei, Theophilus Annan, Seidu A. Richard, Adjoa A. Boakye, Clement O. Tettey, Edward Ken Essuman, Enoch Aninagyei, Precious Agbemeseli

“…Furthermore, estimated daily intake (EDI) of 27.10–283.70 ng/kg·bw/day, margin of exposure (MOE) of 1.409–14.76, average potency of 0–0.00396 ng aflatoxins/kg·bw/day, and cancer risks with a range of 0.107–1.122 cases/100,000 person/yr were observed. Taken together, it could be concluded that consuming cereals pose adverse effects on human health regardless of the age of the consumer.…”
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L’infermiere, una risorsa nel percorso assistenziale degli utenti con disturbo dello spettro autistico by Chiara Cesarini, Giulia Pintus, Emanuele Brai, Alessandro Delli Poggi

“…Introduzione: nel XXI secolo, le persone adulte con disturbo dello spettro autistico (ASD) grave, incontrano ancora innumerevoli ostacoli nell’accedere ai servizi di sanità pubblica e alle prestazioni sanitarie di cui necessitano. …”
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DÖNÜŞÜMCÜ LİDERLİĞİN ÖRGÜTSEL VATANDAŞLIK DAVRANIŞINA ETKİSİ: TÜRKİYE’DE YEREL YÖNETİMLERE DAİR UYGULAMALI BİR ARAŞTIRMA by Sefa ÇETİN, Ceren GİDERLER, Efe EFEOĞLU

“…Söz konusu ölçekte belirlenen dönüşümcü liderlik boyutları; çalışanların başarılarını ödüllendirme / kutlama, personeli gelişimi konusunda cesaretlendirme, örnek olma, paylaşılan farklı bir vizyon yaratma ve süreci sorgulama olarak belirlenmiştir.…”
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Health profile of residents of retirement villages in Auckland, New Zealand: findings from a cross-sectional survey with health assessment by Kathy Peri, Michal Boyd, Martin J Connolly, Joanna B Broad, Dale Bramley, Zhenqiang Wu, Katherine Bloomfield, Joanna Hikaka, Annie Tatton, Cheryl Calvert, Ann-Marie Higgins

“…During the 2 weeks prior to survey, 34% received home supports and 10% personal care. Hypertension, heart disease, arthritis and pain were reported by over 40%. …”
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Bayesian network for predicting mandibular third molar extraction difficulty by Tian Meng, Zhiyong Zhang, Xiao Zhang, Chao Zhang

“…Abstract Background This study aimed to establish a model for predicting the difficulty of mandibular third molar extraction based on a Bayesian network to meet following requirements: (1) analyse the interaction of the primary risk factors; (2) output quantitative difficulty-evaluation results based on the patient’s personal situation; and (3) identify key surgical points and propose surgical protocols to decrease complications. …”
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Empowering biomedical learners to navigate FDA regulatory processes and entrepreneurship with a novel interdisciplinary training approach by Philip A. Cola, Philip A. Cola, Tawna L. Mangosh

“…The flexible course format, team-based learning, and experiential learning proved instrumental in enhancing engagement, reinforcing practical learning outcomes, and supporting personalized learning goals. The flexible course format further aligns with professional needs of participants, providing a model for other institutions navigating similar challenges in biomedical education. …”
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Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment by Annabelle M Belcher, Thomas O Cole, Aaron D Greenblatt, Stephen W Hoag, David H Epstein, Michael Wagner, Amy S Billing, Ebonie Massey, Kristen R Hamilton, Zofia K Kozak, Christopher J Welsh, Eric Weintraub, Emerson M Wickwire, Eric D Wish, Ted J Kaptchuk, Luana Colloca

“…Exploratory outcomes include several environmental as well as personality factors associated with OUD and with propensity to demonstrate a placebo effect.Ethics and dissemination Human subjects oversight for this study is provided by the University of Maryland, Baltimore and University of Maryland, College Park Institutional Review Boards. …”
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Gender Disparities in Medical and Dental Admissions: Students' Perspectives on Barriers by Nabiha Farasat Khan, Muhammad Ilyas, Usama Saeed Usama, Muhammad Saeed, Muhammad Saim, Raz Muhammad

“…Thirty-two first-year female students from the 2024 batch were purposively selected for focus group discussions (FGDs) to explore their personal experiences regarding gender-specific challenges. …”
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Association between frailty, as measured by the FRAIL scale, and 1-year mortality in older patients undergoing hip fracture surgery by Shaohua Xi, Zhibin Wu, Jian Cui, Suran Yin, Shaozhi Xi, Chaoyang Liu

“…The scale can be used to stratify risk and facilitate personalized perioperative treatment and management.…”
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Translation and Validation for the Portuguese Population of the Bedside Handover Attitudes and Behaviors Questionnaire by Cruchinho P, López-Franco MD, Teixeira G, Lucas P, Gaspar F

“…The questionnaire was cross-culturally adapted through translation, translation synthesis, and back-translation procedures, an expert committee harmonization, and two pre-tests.Results: We obtained one factorial solution through exploratory factor analysis that explained 53.5% of the total variance, with 18 items distributed by four components: Direct Engagement, Personal Interaction, Information Sharing, and Individualized Approach. …”
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Economic Diplomacy of the Russian Federation: Prospects for the Development of an Eff ective Export Support System by A. A. Naryshkin

“…This research is based on both offi cial documents and modern academic literature on this issue and on the author’s personal experience gained while working in a number of relevant state institutions and development agencies, as well as commercial organizations. …”
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