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The On-Freezing Phenomenon: Cognitive and Behavioral Aspects
Published 2011-01-01“…Freezing of gait is a warning sign of Parkinson's disease. One could distinguish off-freezing, which is associated with dopaminergic therapy and to its titration, and it is clinically related to wearing-off phenomenon. …”
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82
Parkinsonian Rigidity Shows Variable Properties Depending on the Elbow Joint Angle
Published 2013-01-01“…Then, we measured muscle tone at the elbow joint in 24 Parkinson’s Disease (PD) patients and calculated elastic coefficients in flexion and extension in the ranges of 10°–60° (distal) and 60°–110° (proximal). …”
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Erectile Dysfunction Preceding Clinically Diagnosed α-Synucleinopathies: A Case-Control Study in Olmsted County
Published 2019-01-01“…Autonomic symptoms are common in α-synuclein disorders: multiple system atrophy (MSA), Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and Parkinson’s disease with dementia (PDD). …”
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86
Single Photon Emission Tomography Imaging in Parkinsonian Disorders: A Review
Published 2000-01-01“…Parkinsonian symptoms are associated with a number of neurodegenerative disorders, such as Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy. …”
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87
An overview of methods for the treatment and diagnosis of dementia with Lewy bodies. Clinical case analysis
Published 2020-12-01“…Meanwhile, diagnosed cases of DLB are often detected late because diagnosis at an early stage is difficult as DLB can present in symptoms similar to Alzheimer’s disease, Parkinson’s disease, vascular dementia, delirium, and other disorders. …”
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88
Structure Identification and Risk Assurance of Unknown Impurities in Pramipexole Oral Drug Formulation
Published 2024-01-01“…Pramipexole is a nonergot dopamine agonist used to treat various Parkinson’s disease symptoms. Two unknown impurities were detected from a pramipexole dihydrochloride solid dosage form. …”
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89
Acute β-N-Methylamino-L-alanine Toxicity in a Mouse Model
Published 2015-01-01“…Long-term exposure to L-BMAA is believed to lead to neurodegenerative diseases including Parkinson’s and Alzheimer’s diseases and amyotrophic lateral sclerosis (Lou Gehrig’s disease). …”
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90
Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors.
Published 2023-01-01“…Finally, Tumour necrosis factor alpha plays a key role in these effects, suggesting that this cytokine could be an interesting target to increase the efficacy of human dopaminergic precursors transplantation in Parkinson's Disease.…”
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91
Thyroid-Induced Worsening of Parkinsonian Tremor Resistant to Drugs and Subthalamic Nucleus Deep Brain Stimulation
Published 2014-01-01“…Symptoms of both hypothyroidism and thyrotoxicosis can be easily overlooked in patients with Parkinson’s disease (PD). We report on a patient whose parkinsonian tremor worsened and proved refractory not only to common treatment, but also to deep brain stimulation (DBS). …”
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92
Effect of Zolpidem in the Aftermath of Traumatic Brain Injury: An MEG Study
Published 2020-01-01“…In the past two decades, many studies have shown the paradoxical efficacy of zolpidem, a hypnotic used to induce sleep, in transiently alleviating various disorders of consciousness such as traumatic brain injury (TBI), dystonia, and Parkinson’s disease. The mechanism of action of this effect of zolpidem is of great research interest. …”
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93
Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm
Published 2023-01-01“…In modern medicine, the SSP is most commonly used to diagnose movement disorders such as Parkinson’s disease or the effects of stroke. We hypothesized that SSP could serve as a basis for detecting the risk of affective diseases, including depression. …”
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94
Interaction of Cu(II) and Ni(II) with Ypk9 Protein Fragment via NMR Studies
Published 2014-01-01“…Ypk9 showed manganese detoxification role, preventing a Mn-induced Parkinsonism (PD) besides mutations in Park9, linked to a juvenile form of the disease. …”
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