Mutation Analysis of HTRA2 Gene in Chinese Familial Essential Tremor and Familial Parkinson’s Disease by Ya-Chao He, Pei Huang, Qiong-Qiong Li, Qian Sun, Dun-Hui Li, Tian Wang, Jun-Yi Shen, Juan-Juan Du, Shi-Shuang Cui, Chao Gao, Rao Fu, Sheng-Di Chen

“…HTRA2 has already been nominated as PARK13 which may cause Parkinson’s disease, though there are still discrepancies among these results. …”
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Neuroprotective effects of gastrodin in both in vivo and in vitro models of Parkinson's disease: Mechanisms from the perspective of oxidative stress, ferroptosis, and cellular sene... by Shanshan Li, Meng Wang, Buyun Jia, Baikun Li, Hui Cheng, Shasha Tian, Qinglin Li

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Iron deposition is associated with motor and non-motor network breakdown in parkinsonism by Fangda Leng, Yue Gao, Fan Li, Luhua Wei, Yunchuang Sun, Fang Liu, Ying Zhu, Jianxing Qiu, Zhaoxia Wang, Yiwei Zhang

“…Brain functional network disruption has also been detected in parkinsonism, and is believed to be accountable for specific symptoms in parkinsonism. …”
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Polymorphism in the Vesicular Monoamine Transporter 2 Gene Decreases the Risk of Parkinson’s Disease in Han Chinese Men by Xinglong Yang, Pingrong Xu, Quanzhen Zhao, Ran An, Hua Jia, Zhuolin Liu, Yanming Xu

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Measuring Hemoglobin Levels in the Optic Disc of Parkinson’s Disease Patients Using New Colorimetric Analysis Software by Maria Pilar Bambo, Elena Garcia-Martin, Maria Satue, Susana Perez-Olivan, Silvia Alayon, Marta Gonzalez-Hernandez, Vicente Polo, Jose Manuel Larrosa, Manuel Gonzalez-De la Rosa

“…To evaluate a new method of measuring hemoglobin (Hb) levels and quantifying the color changes in the optic nerve head of Parkinson’s disease (PD) patients. We also compared differences in retinal nerve fiber layer (RNFL) thicknesses obtained using spectral domain optical coherence tomography (OCT) device between PD group and healthy group. …”
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Changes to Intermediary Metabolites in Sporadic and LRRK2 Parkinson’s Disease Demonstrated by Proton Magnetic Resonance Spectroscopy by Jan O. Aasly, Oddbjørn Sæther, Krisztina K. Johansen, Tone F. Bathen, Guro F. Giskeødegård, Linda R. White

“…Background. Parkinson’s disease (PD) remains a clinical diagnosis and biomarkers are needed to detect the disease as early as possible. …”
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Lee Silverman Voice Treatment to Improve Speech in Parkinson’s Disease: A Systemic Review and Meta-Analysis by Tingting Pu, Min Huang, Xiangyu Kong, Meng Wang, Xiangling Chen, Xixi Feng, Changyou Wei, Xiechuan Weng, Fan Xu

“…Speech changes occur in the early stages of Parkinson’s disease (PD) and cause communication difficulties, leading to social isolation. …”
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Dual-task-related gait patterns as possible marker of precocious and subclinical cognitive alterations in Parkinson disease by F. Di Filippo, G. De Biasi, M. Russo, C. Ricciardi, N. Pisani, A. Volzone, M. Aiello, S. Cuoco, M. Calabrese, M. Romano, P. Barone, M. Amboni

“…Abstract Subtle gait and cognitive dysfunction are common in Parkinson’s disease (PD), even before most evident clinical manifestations. …”
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Diagnostic Test to Identify Parkinson’s Disease from the Blood Sera of Chinese Population: A Cross-Sectional Study by Guangan Tong, Pingping Zhang, Wenbin Hu, Kun Zhang, Xianwen Chen

“…Background. Parkinson’s disease (PD) is a neurodegenerative disease, a hallmark by the formation of misfolded and aggregated α-synuclein proteins. …”
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The “Gender Factor” in Wearing-Off among Patients with Parkinson’s Disease: A Post Hoc Analysis of DEEP Study by Delia Colombo, Giovanni Abbruzzese, Angelo Antonini, Paolo Barone, Gilberto Bellia, Flavia Franconi, Lucia Simoni, Mahmood Attar, Emanuela Zagni, Shalom Haggiag, Fabrizio Stocchi

“…Background. The early detection of wearing-off in Parkinson disease (DEEP) observational study demonstrated that women with Parkinson’s disease (PD) carry an increased risk (80.1%) for wearing-off (WO). …”
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Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional studyResearch in context by Kenneth Marek, David S. Russell, Luis Concha-Marambio, Seung Ho Choi, Danna Jennings, Michael C. Brumm, Christopher S. Coffey, Ethan Brown, John Seibyl, Matthew Stern, Claudio Soto, Andrew Siderowf

“…Summary: Background: Synuclein pathology in neurodegenerative diseases, such as Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB), begins years before motor or cognitive symptoms arise. …”
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Long-read sequencing revealed complex biallelic pentanucleotide repeat expansions in RFC1-related Parkinson’s disease by Peng Liu, Fan Zhang, Xinhui Chen, Xiaosheng Zheng, Miao Chen, Zhiru Lin, Shuqi Chen, Lebo Wang, Xinchen Wang, Nan Jin, Chenxin Ying, Fei Xie, Bo Wang, Sheng Wu, Zhidong Cen, Wei Luo

“…Abstract Biallelic intronic pentanucleotide repeat expansions, mainly (AAGGG)exp and/or (ACAGG)exp in RFC1, are detected in cerebellar ataxia, neuropathy and vestibular areflexia syndrome, late-onset ataxia, and in a wide disease spectrum including Charcot-Marie-Tooth disease, multiple system atrophy, and Parkinson’s disease (PD). …”
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Comparing Sensitivity and Specificity of Addenbrooke’s Cognitive Examination-I, III and Mini-Addenbrooke’s Cognitive Examination in Parkinson’s Disease by Tivadar Lucza, Zsuzsanna Ascherman, Márton Kovács, Attila Makkos, Márk Harmat, Annamária Juhász, József Janszky, Sámuel Komoly, Norbert Kovács, Krisztina Dorn, Kázmér Karádi

“…Background. Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterized by numerous motor and nonmotor symptoms. …”
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Astragaloside IV Treats Parkinson’s Disease by Regulating the Proliferation and Differentiation of NSCs through the SHH–Nurr1 Pathway by Zicong Wu, Jianing Zhang, Han Gao, Wentao Li

“…Recently, there has been a surge of interest in enhancing the differentiation of neural stem cells (NSCs) and supplementing dopamine neurons as a potential treatment for Parkinson’s disease, the second most prevalent neurodegenerative disorder. …”
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Deciphering Parkinson’s Disease through Eye Movements: A Promising Tool for Early Diagnosis in the Face of Cognitive Impairment by Xianglian Liao, Jian Yao, Hongyin Tang, Yilan Xing, Xin Zhao, Daao Nie, Ping Luan, Guihua Li

“…Cognitive dysfunction is the most common and important nonmotor symptom in Parkinson’s disease (PD) and can occur at any stage. …”
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PD_EBM: An Integrated Boosting Approach Based on Selective Features for Unveiling Parkinson's Disease Diagnosis With Global and Local Explanations by Fahmida Khanom, Mohammad Shorif Uddin, Rafid Mostafiz

“…ABSTRACT Early detection and characterization are crucial for treating and managing Parkinson's disease (PD). …”
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Quantitative Analysis of Motor Status in Parkinson’s Disease Using Wearable Devices: From Methodological Considerations to Problems in Clinical Applications by Masahiko Suzuki, Hiroshi Mitoma, Mitsuru Yoneyama

“…Long-term and objective monitoring is necessary for full assessment of the condition of patients with Parkinson’s disease (PD). Recent advances in biotechnology have seen the development of various types of wearable (body-worn) sensor systems. …”
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Subthalamic hGAD65 Gene Therapy and Striatum TH Gene Transfer in a Parkinson’s Disease Rat Model by Deyu Zheng, Xiaohua Jiang, Junpeng Zhao, Deyi Duan, Huanying Zhao, Qunyuan Xu

“…The aim of the present study is to detect a combination method to utilize gene therapy for the treatment of Parkinson’s disease (PD). …”
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On-Demand Gait-Synchronous Electrical Cueing in Parkinson's Disease Using Machine Learning and Edge Computing: A Pilot Study by Ardit Dvorani, Constantin Wiesener, Christina Salchow-Hommen, Magdalena Jochner, Lotta Spieker, Matej Skrobot, Hanno Voigt, Andrea Kuhn, Nikolaus Wenger, Thomas Schauer

“…<italic>Goal:</italic> Parkinson&#x0027;s disease (PD) can lead to gait impairment and Freezing of Gait (FoG). …”
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Optimizing Parkinson’s Disease Prediction: A Comparative Analysis of Data Aggregation Methods Using Multiple Voice Recordings via an Automated Artificial Intelligence Pipeline by Zhengxiao Yang, Hao Zhou, Sudesh Srivastav, Jeffrey G. Shaffer, Kuukua E. Abraham, Samuel M. Naandam, Samuel Kakraba

“…We developed a customized AI pipeline that incorporates twelve machine learning algorithms along with the four aggregation methods to detect Parkinson’s disease (PD) using multiple voice recordings from individuals available in the UCI Machine Learning Repository, which includes 756 voice recordings from 188 PD patients and 64 healthy individuals. …”
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