Development of a multi-epitope chimeric vaccine in silico against Babesia bovis, Theileria annulata, and Anaplasma marginale using computational biology tools and reverse vaccinolo... by Amam Zonaed Siddiki, Sabreena Alam, Farhan Fuad Bin Hossen, Md Abdul Alim

“…The three rickettsial parasites- Babesia bovis, Theileria annulata and Anaplasma Marginale are responsible for causing Babesiosis, Theileriosis and Anaplasmosis among cattle. …”
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Preventing Foodborne Illness: Cyclosporiasis by Christopher Pabst, Jaysankar De, Renée Goodrich Schneider, Keith R. Schneider

“… Cyclosporiasis is an intestinal illness caused by the microscopic parasite Cyclospora cayetanensis. People can become infected with Cyclospora by consuming food or water contaminated with the parasite. …”
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Prevalence and Intensity of Soil-Transmitted Helminths and Associated Factors among Adolescents and Adults in Bibugn Woreda, Northwest Ethiopia: A Community-Based Cross-Sectional S... by Abrham Goshu, Getaneh Alemu, Animen Ayehu

“…Fecal egg counts revealed that 96.5% (112/116) of the infections were with light parasite intensity, while 3.5% (4/116) were with moderate parasite intensity. …”
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Chagas Disease: Still Many Unsolved Issues by José M. Álvarez, Raissa Fonseca, Henrique Borges da Silva, Cláudio R. F. Marinho, Karina R. Bortoluci, Luiz R. Sardinha, Sabrina Epiphanio, Maria Regina D'Império Lima

“…Over the past 20 years, the immune effector mechanisms involved in the control of Trypanosoma cruzi, as well as the receptors participating in parasite recognition by cells of the innate immune system, have been largely described. …”
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Trypanosoma cruzi SSP4 Amastigote Protein Induces Expression of Immunoregulatory and Immunosuppressive Molecules in Peripheral Blood Mononuclear Cells by Yadira Morán-Utrera, Aracely López-Monteon, José Luis Rosales-Encina, Enrique Méndez-Bolaina, Angel Ramos-Ligonio

“…This mechanism of evasion allows the parasite to spread in the host. Parasite molecules that regulate the host immune response during Chagas’ disease have not been fully identified, particularly proteins of the amastigote stage. …”
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Pharmacological inhibition of key metabolic pathways attenuates Leishmania spp infection in macrophages. by Elaine Carvalho de Oliveira, Rafael Tibúrcio, Gabriela Duarte, Amanda Lago, Léon de Melo, Sara Nunes, Gustavo Gastão Davanzo, Ana Júlia Martins, Bruno Vinagre Ribeiro, Deborah Mothé, Juliana B P Menezes, Patrícia Veras, Natalia Tavares, Pedro M Moraes-Vieira, Cláudia Ida Brodskyn

“…To investigate the metabolic pathways required for Leishmania amastigotes to persist in BMDMs, we pre-treated cells with small molecule drugs that target major metabolic pathways, revealing that perturbations in several metabolic processes affected parasite survival in a strain-independent manner. Treatments with inhibitors of the oxidative phosphorylation and glycolysis substantially reduced parasite loads. …”
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Necrotizing Lung Infection Caused by the Protozoan Balantidium coli by Sat Sharma, Godfrey Harding

“…Bronchoalveolar lavage fluid examined for ova and parasite revealed trophozoites of B coli in large numbers. …”
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Preventing Foodborne Illness: Cyclosporiasis by Christopher Pabst, Jaysankar De, Renée Goodrich Schneider, Keith R. Schneider

“… Cyclosporiasis is an intestinal illness caused by the microscopic parasite Cyclospora cayetanensis. People can become infected with Cyclospora by consuming food or water contaminated with the parasite. …”
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Moving “Forward” in Plasmodium Genetics through a Transposon-Based Approach by Bharath Balu

“…The genome sequence of the human malaria parasite, Plasmodium falciparum, was released almost a decade ago. …”
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A reaction-diffusion system modeling the spread of resistance to an antimalarial drug by Nicolas Bacaër, Cheikh Sokhna

“…Resistance can spread only whenthe basic reproduction number of the resistant parasites is biggerthan the basic reproduction number of the sensitive parasites(which depends on the fraction of infected people treated with theantimalarial drug). …”
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The phytoplasma SAP54 effector acts as a molecular matchmaker for leafhopper vectors by targeting plant MADS-box factor SVP by Zigmunds Orlovskis, Archana Singh, Adi Kliot, Weijie Huang, Saskia A Hogenhout

“…Obligate parasites often trigger significant changes in their hosts to facilitate transmission to new hosts. …”
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Stage-specific function of sphingolipid synthases in African trypanosomes by Norton Heise, Carolina M. Koeller, Mohamed Sharif, James D. Bangs

“…ABSTRACT The protozoan parasite Trypanosoma brucei is the only known eukaryote capable of synthesizing the three main phosphosphingolipids: sphingomyelin (SM), inositol phosphorylceramide (IPC), and ethanolamine phosphorylceramide (EPC). …”
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Protozoocidal activity of Stemona collinsiae against Giardia duodenalis by Khuanchai Koompapong, Supaluk Popruk, Onrapak Reamtong, Tipparat Thiangtrongjit, Sumate Ampawong, Aurapa Sakulpanich, Ruenruetai Udonsom, Kanthinich Thima, Preeyaporn M. Sreepian, Kittiyod Poovorawan, Hirotake Mori, Christen Rune Stensvold, Aongart Mahittikorn

“…Dichloromethane and hexane extracts were highly active against the parasite after 48 h of exposure, with half-maximal inhibitory concentration (IC50) values of 60.77 μg/mL and 66.66 μg/mL, respectively. …”
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Interaction of human neutrophils with Trichomonas vaginalis protozoan highlights lactoferrin secretion by Wei-Hung Cheng, Ruei-Min Chen, Seow-Chin Ong, Yuan-Ming Yeh, Po-Jung Huang, Chi-Ching Lee

“…The precise reasons behind T. vaginalis actively promoting interaction between parasites and neutrophils rather than inhibiting the inflammatory response remain unclear. …”
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Interactions between Leishmania braziliensis and Macrophages Are Dependent on the Cytoskeleton and Myosin Va by Elisama Azevedo, Leandro Teixeira Oliveira, Ana Karina Castro Lima, Rodrigo Terra, Patrícia Maria Lourenço Dutra, Verônica P. Salerno

“…In activated cells, the loss of cytoskeletal components inhibited the release of IL-10 during parasite interactions. The production of IL-10 also decreased in the absence of actin or microtubules in non-activated macrophages. …”
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Magnitude, Severity, and Associated Factors of Anemia among Under-Five Children Attending Hawassa University Teaching and Referral Hospital, Hawassa, Southern Ethiopia, 2016 by Yeshimebet Gebereselassie, Mesganaw BirhanSelassie, Tadesse Menjetta, Jemal Alemu, Aster Tsegaye

“…Stool samples were collected and processed using direct wet mount and formol-ether concentration method to detect intestinal parasites. Data were entered and analyzed using SPSS version 20 statistical packages. …”
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Development of a Loop Mediated Isothermal Amplification for Diagnosis of Ascaris lumbricoides in Fecal Samples by Esther A. Shiraho, Agola L. Eric, Ibrahim N. Mwangi, Geoffrey M. Maina, Joseph M. Kinuthia, Martin W. Mutuku, Robert M. Mugambi, Jackson M. Mwandi, Gerald M. Mkoji

“…Ascaris lumbricoides is a nematode parasite that causes the common tropical infection ascariasis in humans. …”
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Proteomic Identification and Functional Analysis of Babesia microti Reveals Heparin-Binding Proteins by Yu Chun Cai, Bin Xu, Yan Hong Chu, Ying Fang Yu, Jia Hui Sun, Zi Ran Mo, Han Yin Yang, Shu Ning Yan, Mu Xin Chen, Jia Xu Chen

“…Heparan sulfate, a type of GAG molecule, has been identified as an important receptor facilitating the invasion of red blood cells by these parasites. Proteins in the parasite that exhibit strong affinity for heparin may play a pivotal role in this invasion process. …”
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Challenges in Laboratory Diagnosis of Malaria in a Low-Resource Country at Tertiary Care in Eastern Nepal: A Comparative Study of Conventional vs. Molecular Methodologies by Pragyan Dahal, Basudha Khanal, Keshav Rai, Vivek Kattel, Satish Yadav, Narayan Raj Bhattarai

“…These methods are entirely dependent on the course of infection, parasite load, and skilled technical resources. Our study objectives were to estimate the performance of light microscopy and a RDT as well as real-time PCR for the detection of the Plasmodium parasite. …”
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4-Aminoquinoline as a privileged scaffold for the design of leishmanicidal agents: structure–property relationships and key biological targets by Angel H. Romero, Francisco Delgado

“…Moreover, beyond the pharmacological exigencies, there are other challenges concerning its parasitic nature, such as its great genetic plasticity and adaptability, enabling it to activate a battery of genes to develop resistance quickly. …”
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