-
941
Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure
Published 2025-01-01“…Overall, two-photon NAD(P)H-FLIM proved to be a powerful tool for studying specific metabolic pathways in Ascaris larvae and host macrophages, offering valuable insights into the metabolic mechanisms of drug action on both parasite and host.…”
Get full text
Article -
942
Status of the Multidrug Resistance-1 Gene of Plasmodium falciparum in Four Malaria Epidemiological Strata, Two Decades after the Abolition of Chloroquine as First-Line Treatment fo...
Published 2023-01-01“…Drug-resistant malaria parasites pose a threat to global malaria control efforts, and it is important to know the extent of these drug-resistant mutations in each region to determine appropriate control measures. …”
Get full text
Article -
943
High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.
Published 2013-01-01“…<h4>Background/objectives</h4>Human leishmaniases are parasitic diseases causing severe morbidity and mortality. …”
Get full text
Article -
944
Recent Advances in Understanding the Inflammatory Response in Malaria: A Review of the Dual Role of Cytokines
Published 2021-01-01“…During blood-stage infection, in response to the presence of the parasite, the host’s immune system produces proinflammatory cytokines including IL-6, IL-8, IFN-γ, and TNF, cytokines which play a pivotal role in controlling the growth of the parasite and its elimination. …”
Get full text
Article -
945
Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum
Published 2014-01-01“…Emergence of rapid drug resistance to existing antimalarial drugs in Plasmodium falciparum has created the need for prediction of novel targets as well as leads derived from original molecules with improved activity against a validated drug target. The malaria parasite has a plant plastid-like apicoplast. To overcome the problem of falciparum malaria, the metabolic pathways in parasite apicoplast have been used as antimalarial drug targets. …”
Get full text
Article -
946
Tropical Medicine in China: Bibliometric Analysis Based on Web of Science (2010–2019)
Published 2021-01-01“…The United States ranked first in internationally collaborative articles with China. Furthermore, Parasite & Vectors, which published 707 papers, emerged as the top journal according to the number of publications. …”
Get full text
Article -
947
Isolation and Identification of Toxoplasma gondii from Aborted Fetuses of Goats by PCR in Lorestan Province
Published 2024-07-01“…Background: A zoonotic obligate intracellular protozoan parasite, Toxoplasma gondii, infects all warm-blooded animals as well as humans worldwide. …”
Get full text
Article -
948
Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype.
Published 2025-01-01“…Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a diverse family of variant surface antigens, encoded by var genes, that mediates binding of infected erythrocytes to human cells and plays a key role in parasite immune evasion and malaria pathology. The increased availability of parasite genome sequence data has revolutionised the study of PfEMP1 diversity across multiple P. falciparum isolates. …”
Get full text
Article -
949
Implementing an environmental DNA/RNA-based approach to non-invasively investigate disease caused by Ichthyophthirius multifiliis
Published 2025-03-01“…Simultaneously, the parasite burden and immune-relevant gene expression in both water and fish gills were investigated. …”
Get full text
Article -
950
IgM against Merozoite Surface Protein 1-Block 2 Haplotypes as New Tools for Plasmodium vivax Infections
Published 2024-12-01“…We evaluated seroprevalence against sets of specific peptides to the block 2 region of Plasmodium vivax-merozoite surface protein-1 (PvMSP1) to detect parasite clones. Methods: We applied amplicon deep sequencing (ADS) of block 2 region of the MSP-1 gene (pvmsp1) to determine cocirculating parasite clones within eight P. vivax-infected individuals. …”
Get full text
Article -
951
TLR Specific Immune Responses against Helminth Infections
Published 2017-01-01“…The role of TLR expression and function in relation to intracellular parasites has been documented but limited studies are available for multicellular helminth parasites. …”
Get full text
Article -
952
Seasonal Profile and Five-Year Trend Analysis of Malaria Prevalence in Maygaba Health Center, Welkait District, Northwest Ethiopia
Published 2021-01-01“…Plasmodium falciparum and Plasmodium vivax were the dominant parasites detected, which accounted for 66.1%; N=4832, 33.9%; N=2477, respectively. …”
Get full text
Article -
953
Taxonomic and functional diversity of protists in saline and hypersaline lakes in southern Western Siberia, a region strongly affected by climate change
Published 2025-01-01“…The parasite amplicon sequence variants (ASVs) were affiliated mainly with mixohaline and beta-hypersaline lakes.…”
Get full text
Article -
954
Antimicrobial Susceptibility Patterns of Shigella Species among Children under Five Years of Age with Diarrhea in Selected Health Centers, Addis Ababa, Ethiopia
Published 2023-01-01“…Background. Shigella and parasitic infections are common public health problems throughout the world. …”
Get full text
Article -
955
The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses.
Published 2012-01-01“…Located inside the tegument, the molecule belongs to a family of proteins from parasitic platyhelminths, the Tegument-Allergen-Like proteins (TALs). …”
Get full text
Article -
956
Anemia and Associated Factors among Public Elementary School Children in Asella Town, Southeast Ethiopia: A Facility-Based Cross-Sectional Study
Published 2024-01-01“…Uneducated mothers, intestinal parasite infections, and underweight children were found to be determinants of anemia among school-age children. …”
Get full text
Article -
957
Prevalence of Helminthic Infections in the Gastrointestinal Tract of Cattle in Mazandaran Province (Northern Iran)
Published 2022-01-01“…Ruminant parasites are found in all parts of the world, including the tropical and subtropical regions. …”
Get full text
Article -
958
Lysophosphatidylcholine: A Novel Modulator of Trypanosoma cruzi Transmission
Published 2012-01-01“…It acts as a powerful chemoattractant for inflammatory cells at the site of the insect bite, which will provide a concentrated population of cells available for parasite infection. Also, LPC increases macrophage intracellular calcium concentrations that ultimately enhance parasite invasion. …”
Get full text
Article -
959
Diatoms-endoparasite association in fish from the marine pacific coast of Colombia (Buenaventura).
Published 2024-01-01“…The association of parasites and diatoms has been previously reported as an important mechanism to control bacteria and parasites to avoid resistance to chemical usage. …”
Get full text
Article -
960
Current Enzooticity of <i>Dirofilaria immitis</i> and <i>Angiostrongylus vasorum</i> in Central and Southern Italy
Published 2025-01-01“…A high level of vigilance and routine parasitological screening are necessary, considering the high prevalence of intestinal parasites in owned dogs that are also co-infected by respiratory parasites. …”
Get full text
Article