Controlled human malaria infection: overview and potential application in the evaluation of transmission-blocking interventions in malaria-endemic areas by Enock J. Kessy, Ally I. Olotu

“…Abstract Controlled human malaria infection (CHMI) involves the intentional infection of healthy individuals with malaria parasites, close observation of the volunteers, and clearance of the parasite at a predetermined endpoint. …”
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The Role of Pathogens in Bumblebee Decline: A Review by Huanhuan Chen, Nawaz Haider Bashir, Qiang Li, Chao Liu, Muhammad Naeem, Haohan Wang, Wenrong Gao, Richard T. Corlett, Cong Liu, Mayra C. Vidal

“…The current study provides a comprehensive review of how pathogens and parasites contribute to the decline of bumblebee species. …”
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Novel Arsenic Nanoparticles Are More Effective and Less Toxic than As (III) to Inhibit Extracellular and Intracellular Proliferation of Leishmania donovani by Sudipta Chakraborty, Kaushik Bhar, Sandip Saha, Rajarshi Chakrabarti, Anjali Pal, Anirban Siddhanta

“…Visceral leishmaniasis, a vector-borne tropical disease that is threatening about 350 million people worldwide, is caused by the protozoan parasite Leishmania donovani. Metalloids like arsenic and antimony have been used to treat diseases like leishmaniasis caused by the kinetoplastid parasites. …”
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Extensive Inactive Neurocysticercosis: A Case Report in Mbeya, Southern Highlands of Tanzania by Makasi CE, Ngowi BJ, Stelzle D, Kilale AM, Mahande MJ, Welte TM, Winkler AS, Mmbaga BT

“…It is influenced by the number, size, location, and stage of the cysts, as well as the parasite’s potential to cause inflammation and the immunological response of the host. …”
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Improving Accuracy of Malaria Diagnosis in Underserved Rural and Remote Endemic Areas of Sub-Saharan Africa: A Call to Develop Multiplexing Rapid Diagnostic Tests by Rasheed O. Makanjuola, Andrew W. Taylor-Robinson

“…Clinical infection with malaria, caused by parasites of the genus Plasmodium, is considered a serious medical condition with the potential to become a life-threatening emergency. …”
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Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization by Junpei Fukumoto, Minako Yoshida, Suzumi M. Tokuoka, Eri Saki H. Hayakawa, Shinya Miyazaki, Takaya Sakura, Daniel Ken Inaoka, Kiyoshi Kita, Jiro Usukura, Hideo Shindou, Fuyuki Tokumasu

“…Abstract The rapid intraerythrocytic replication of Plasmodium falciparum, a deadly species of malaria parasite, requires a quick but constant supply of phospholipids to support marked cell membrane expansion. …”
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Very low prevalence of Plasmodium falciparum histidine-rich protein 2 (pfhrp2) gene deletion in the Brazil, Venezuela, and Guyana tri-border by Maria Eduarda Pereira Mascarenhas, Jaime Louzada, Renato Amorim Rosa, Gabriela Maíra Pereira de Assis, Flora Satiko Kano, Joseli Oliveira-Ferreira, Tais Nobrega de Sousa

“…Our findings point to a low prevalence (1%) of pfhrp2-deleted parasites confirmed by the lack of HRP2 detection. …”
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Trend of Soil-Transmitted Helminths in Ethiopian Children: A Systematic Review and Meta-Analysis (2000-2018) by Getaneh Alemu, Feleke Mekonnen, Mezgebu Nega, Chalachew Muluneh

“…As a result, the nation has been implementing mass drug administration, water, sanitation, and hygiene and health extension programs to control those parasites. Hence, updated data about the prevalence and trend of parasites over time has a pivotal role to assess the success of existing control programs. …”
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Cysticerci Drive Dendritic Cells to Promote In Vitro and In Vivo Tregs Differentiation by Laura Adalid-Peralta, Asiel Arce-Sillas, Gladis Fragoso, Graciela Cárdenas, Marcos Rosetti, Didier Casanova-Hernández, Claudia Rangel-Escareño, Laura Uribe-Figueroa, Agnes Fleury, Edda Sciutto

“…Treg induction is a strategy that parasites have evolved to modulate the host’s inflammatory environment, facilitating their establishment and permanence. …”
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The development and maintenance of immunity against visceral leishmaniasis by Rahul Tiwari, Awnish Kumar, Vishal Kumar Singh, Rajneesh, Shashi Bhushan Chauhan, Shyam Sundar, Susanne Nylén, Christian Engwerda, Rajiv Kumar

“…Understanding the development and maintenance of immunological memory is important for efforts to eliminate parasitic diseases like leishmaniasis. Leishmaniasis encompasses a range of pathologies, resulting from infection with protozoan parasites belonging to the subgenera Leishmania and Viannia of the genus Leishmania. …”
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Trichodinid (Ciliophora: Peritrichida) Ectoparasites of Sand Goby (Oxyeleotris marmorata) Fry by D. Dana, Kusman Sumawidjaja, Yani Hadiroseyani

“…ABSTRACT Two species of Trichodinid were identified from sand goby, (Oxyeleotris marmorata) fry of 6,1-8,0 mm long; T heterodentata and T nigra.  All parasite species were scraped from the skin of fry which were reared in fertilized pond. …”
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Genome-editing opportunities to enhance cattle productivity in the tropics by Luiz Sergio de Almeida Camargo, Jorge Fernando Pereira

“…Abstract The livestock performance in tropical regions has been limited by environmental conditions that causes heat stress and favors the development of parasites and diseases, impairing animal health. Heat stress disturbs animal homeostasis and affects animal production and fertility, with negative impacts on meat and milk quality. …”
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High Throughput Approaches to Unravel the Mechanism of Action of a New Vanadium-Based Compound against Trypanosoma cruzi by M. Florencia Mosquillo, Pablo Smircich, Analía Lima, Sergio A. Gehrke, Gonzalo Scalese, Ignacio Machado, Dinorah Gambino, Beatriz Garat, Leticia Pérez-Díaz

“…Concordantly, no drastic changes of the parasite transcriptome were detected after 6 h of treatment. …”
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Morphological Characterization of Emerging Cercariae among Lymnaeid Snails from Barangay Cawongan, Padre Garcia, Batangas, Philippines by Gregorio L. Martin I, Esperanza C. Cabrera

“…Lymnaeid snails are the known intermediate hosts of the liver fluke Fasciola spp. and therefore play an important role in the parasite’s life cycle. The study is conducted to determine specificity of snail host-parasite interaction and to determine the snail-trematode infection rate by cercarial emergence, characterizing the emerging larvae using standardized key. …”
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Malaria Microscopy Competency in the Subnational Verification, China: Implications for Malaria Elimination and the Prevention of Malaria Reestablishment by Mei Li, Fang Huang, Jianhai Yin, He Yan, Shuisen Zhou, Zhigui Xia

“…The qualitative accuracy was higher than 90% each (P=0.137), but slides with low parasite density were easy to be misdiagnosed as negative. …”
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The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum by Alexander A. Morano, Wei Xu, Francesca M. Navarro, Neeta Shadija, Jeffrey D. Dvorin, Hangjun Ke

“…Our use of long-term, live-cell microscopy allows for the visualization of apicoplast and mitochondrial division in live parasites at super resolution for the first time, and demonstrates that in PfDyn2-deficient parasites, while the apicoplast and mitochondrion increase in size and complexity, they do not undergo fission. …”
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Uncovering the Mechanism of Action of Antiprotozoal Agents: A Survey on Photoaffinity Labeling Strategy by Alessandro Giraudo, Cristiano Bolchi, Marco Pallavicini, Roberto Di Santo, Roberta Costi, Francesco Saccoliti

“…<i>Plasmodium</i>, <i>Leishmania</i>, and <i>Trypanosoma</i> parasites are responsible for infectious diseases threatening millions of people worldwide. …”
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The haustorium as a driving force for speciation in thallus-forming Laboulbeniomycetes by Danny Haelewaters, Maarten Lubbers, André De Kesel

“…Abstract Laboulbeniomycetes is a class of fungi that have obligate associations with arthropod hosts, either for dispersal (order Pyxidiophorales) or as biotrophic parasites (orders Herpomycetales and Laboulbeniales). …”
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Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome. by Lucy B Ochola, Bethsheba R Siddondo, Harold Ocholla, Siana Nkya, Eva N Kimani, Thomas N Williams, Johnstone O Makale, Anne Liljander, Britta C Urban, Pete C Bull, Tadge Szestak, Kevin Marsh, Alister G Craig

“…This is a complex system involving several host receptors and a major parasite-derived variant antigen (PfEMP1) expressed on the surface of the infected erythrocyte membrane. …”
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Adaptive Genetic Traits in Human Populations: Evolutionary Responses to Malaria by Arun Ghosh, Aparna Ajith S, Abhijith Pradeep

“…The disease is caused by Plasmodium parasites and spread through mosquito bites. This review investigates the genetic adaptations that humans have developed over time as a response to malaria. …”
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