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1841
Proteome-Wide Identification and Comparison of Drug Pockets for Discovering New Drug Indications and Side Effects
Published 2025-01-01“…Notably, many druggable pockets were found in less studied proteins, suggesting untapped therapeutic opportunities. The results of a pairwise pocket similarity analysis identified 220,312 similar pocket pairs, with 3241 pairs across different protein families, indicating shared drug-binding potential. …”
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1842
Expression of O6-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients
Published 2010-01-01“…MGMT varied widely from 42–253 fmoles/mg protein and from 3.2–40 fmoles/μg DNA in normal and 58–468 fmoles/mg protein and 2.5–49.5 fmoles/mg protein, in the tumour tissues; only one tumour had undetectable activity. Pairwise comparison of MGMT activity in tumour and adjacent normal tissue showed no significant difference based on DNA content but was 1.75-fold higher in tumour (P<.01) based on protein. …”
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1843
Advanced groundwater potential and contamination vulnerability assessment using integrated GIS-based AHP techniques: A case study from the Bizerte watershed, Tunisia
Published 2025-06-01“…Weights were assigned via an AHP-based pairwise comparison matrix and integrated using Geographic Information System (GIS) technology to generate a groundwater potential map. …”
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1844
Genetic Diversity and Population Structure of <i>Macrobrachium nipponense</i> Populations in the Saline–Alkaline Regions of China
Published 2025-01-01“…The genetic distance (D) and the pairwise genetic differentiation index (F<sub>ST</sub>) revealed that SD and GS are closely related. …”
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1845
Transmission of Genetic Variation from the Adult Generation to Naturally Established Seedlings of Fagus orientalis in the Hyrcanian Forest
Published 2024-09-01“…In total, 75 private alleles were detected; of these, 56 were rare and had a frequency below 0.05. Pairwise Fst values indicated that seedlings were more similar to each other than to mature trees in the same population. …”
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1846
Preoxygenation strategies before intubation in patients with acute hypoxic respiratory failure: a network meta-analysis
Published 2025-02-01“…Data were extracted and analyzed using pairwise and network meta-analysis within a Bayesian framework. …”
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1847
Does the seed fall far from the tree? Weak fine-scale genetic structure in a continuous Scots pine population
Published 2024-04-01“…We genotyped almost 500 adult trees for 150k SNPs using a custom made Affymetrix array. We detected some pairwise relatedness at short distances, but the average relatedness was low and decreased with increasing distance, as expected. …”
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1848
Comparative analysis of combined methylene blue photodynamic therapy and doxorubicin treatment of oral squamous cell carcinoma cell line: In vitro study on apoptosis
Published 2025-02-01“…Analysis of variance (ANOVA) was used to compare quantitative variables between groups, and Tukey's test was applied for pairwise group comparisons. Results: Flow cytometry analysis revealed that the highest level of cellular apoptosis occurred in the group treated with PDT in conjunction with doxorubicin. …”
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1849
Nonparametric analysis of inter‐individual relations using an attention‐based neural network
Published 2021-08-01“…Abstract Social network analysis, which has been widely adopted in animal studies over the past decade, enables the revelation of global characteristic patterns of animal social systems from pairwise inter‐individual relations. Animal social networks are typically drawn based on the geometric proximity and/or frequency of social behaviours (e.g. grooming), but the appropriate metric for inter‐individual relationship is not clear, especially when prior knowledge on the species/data is limited. …”
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1850
A Critical Review on the Book Qesse-ye Solayman (An Ancient Text of Azarbaijan’s Regional Variety of Persian)
Published 2021-11-01“…This book has been edited critically by Alireza Imami and Ardowan Amiri-Nezhad and published by Oqāf-e Dr Afshar with Sokhan publication. …”
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1851
Evaluation of the Inductive Coupling between Coplanar Concentric Coils in the Presence of the Ground
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1852
Feasibility and Effectiveness of Telephone-Based Telephysiotherapy for Treatment of Pain in Low-Resource Setting: A Retrospective Pre-Post Design
Published 2020-01-01“…The data were analyzed using ANOVA with repeated measures followed by pairwise comparisons. Results. Fifteen patients having pain due to various conditions participated in the study. …”
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1853
Low-density SNP marker sets for genetic variation analysis and variety identification in cultivated citrus
Published 2025-02-01“…Significant genetic differentiations between three populations were also found using the pairwise F st. In addition, interspecific hybrids showed higher level of genetic diversity relative to the C. unshiu and C. sinensis populations. …”
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1854
Did Turkey Experience Reductions in Air Pollution During The Covid-19 Lockdown and Partial Lockdown?
Published 2024-01-01“…The non-parametric Kruskal Wallis test, followed by the Dunn's Bonferroni test for pairwise comparison, was employed to determine the differences in air quality between years. …”
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1855
Micro CT evaluation of marginal discrepancies of endocrown restored molars with different intrapulpal depths and materials of fabrication. (in-vitro study)
Published 2025-01-01“…The highest value was found in samples with 4 mm extension (84.35 ± 18.16), followed by samples with 2 mm extension (66.52 ± 21.86), while the lowest value was found in samples without pulpal extension (59.41 ± 22.16). Post hoc pairwise comparisons showed samples with 4 mm extension to have a significantly higher value than samples without extension (p < 0.001). …”
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1856
Capturing spatiotemporal variation in salt marsh belowground biomass, a key resilience metric, through geoinformatics
Published 2024-12-01“…We sought to characterize variation in S. alterniflora BGB over both temporal and spatial gradients through extensive marsh field observations in coastal Georgia, USA, to quantify their relationship with a suite of predictor variables, and to use these results to improve performance and expand the parameter space of BERM. We conducted pairwise comparisons of S. alterniflora growth metrics measured at nine sites over 3–8 years and found that BGB grouped by site differed in 69% of comparisons, while only in 21% when grouped by year. …”
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1857
The algebraic extended atom-type graph-based model for precise ligand–receptor binding affinity prediction
Published 2025-01-01“…This approach leverages the eigenvalues and eigenvectors of graph Laplacian and adjacency matrices to capture high-level details of specific atom pairwise interactions. Evaluated against benchmark datasets such as CASF-2016, CASF-2013, and the Cathepsin S dataset, the AGL-EAT-Score demonstrates notable accuracy, outperforming existing traditional and ML-based methods. …”
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1858
Genetic diversity and differentiation of cultured Nile tilapia populations from Ethiopia revealed by ddRAD-seq: implications for better hatchery management
Published 2025-01-01“…Expected heterozyosity (He), observed heterozygosity (Ho) and nucleotide diversity (π) estimates indicated moderate within-population genetic diversity (mean: He = 0.24, Ho = 0.25, π = 0.25). Pairwise FST values revealed the highest genetic distance (FST = 0.067) between Batu and Aweday populations, while the lowest genetic distance (FST = 0.027) was observed between Sebeta and Aweday populations. …”
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1859
Utilizing GIS, remote sensing, and AHP-multi-criteria decision analysis for optimal landfill site selection in Kenitra Province, Morocco: a step towards sustainable development goa...
Published 2025-01-01“…Maps for each criterion were generated, and pairwise comparisons were used to assign weights to these factors. …”
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1860
Relationships between the allozyme and phenotypic diversities of Picea ajanensis populations
Published 2015-12-01“…Phenotypic variability of spruce populations was estimated based on the composition of morphotypes that were identified by using geometric morphometrics of cone-scale shapes. Pairwise comparison of samples of cones from 170 trees from six populations revealed 12 morphotypes differing in the shape of cone scales. …”
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