Randomised, pragmatic, waitlist controlled trial of cannabis added to prescription opioid support on opioid dose reduction and pain in adults with chronic non-cancer pain: study protocol by A Eden Evins, Ellie Grossman, Julia Jashinski, Aurora Quaye, Corinne Cather, Kevin Potter, David A Schoenfeld, Jodi M Gilman

“…Introduction Chronic, non-cancer pain impacts approximately 50 million adults in the USA (20%), approximately 25% of whom receive chronic prescription opioids for pain despite limited empirical efficacy data and strong dose-related risk for opioid use disorder and opioid overdose. …”
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SARS-CoV-2 risk factors among symptomatic vaccinated adults attending community testing locations in the Netherlands from June 2021 till February 2022. by Claudia Laarman, Susan J Hahné, Hester E de Melker, Mirjam J Knol

“…<h4>Methods</h4>In a test-negative case control study among vaccinated adults attending community COVID-19 testing locations between June 1st 2021 till February 28th 2022, we compared symptomatic cases with symptomatic controls (to study risk factors specific for SARS-CoV-2) and with asymptomatic controls (to study risk factors that could apply to respiratory infections in general). …”
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Association between fish intake and incidence of sarcopenia in community-dwelling older adults after a 6-year follow-up: the Korean frailty and aging cohort study by Seunghyun Yi, Miji Kim, Chang Won Won, Yongsoon Park

Subjects: “…community-dwelling older adults…”
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Adult Height after Growth Hormone Treatment at Pubertal Onset in Short Adolescents Born Small for Gestational Age: Results from a Belgian Registry-Based Study by M. Thomas, D. Beckers, C. Brachet, H. Dotremont, M.-C. Lebrethon, P. Lysy, G. Massa, N. Reynaert, R. Rooman, S. van der Straaten, M. Roelants, J. De Schepper

“…Information on the efficacy of GH treatment in short SGA children starting their treatment in adolescence is limited. Therefore, adult height (AH), total height gain, and pubertal height gain were evaluated in short SGA children who started GH treatment at pubertal onset. …”
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Serum uric acid to creatinine ratio as a predictor of insulin resistance, β cell function, and metabolic syndrome in normal Korean adults: a cross-sectional study by Misuk Oh, Soo Hyun Cho

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New Species of Rheotanytarsus Thienemann and Bause (Diptera: Chironomidae: Tanytarsini) from Darjeeling–Sikkim, Himalaya, India, with Revised Keys to the Adult Males and Pupae of the Species of the Oriental Region by Niladri Hazra, Shubhranil Brahma, Kaushik Sanyal

“…R. nudicornus n. sp. belonging to the aquilus species group is described as adult male and pupa, R. spinicornus n. sp. in the muscicola group is described as adult male, pupa, and larva, and R. caputimberus in the trivittatus group is described as adult male with damaged pupa. …”
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Progress on HIV and other sexually transmitted infections elimination among youth and adults across BRICS-plus countries: Results from the Global Burden of Disease Study 2021 by Rizhen Wang, Yinuo Sun, Huan Wang, Xiaoran Yu, JiYan Ma, Zuokun Liu, Jing Li, Zhiyong Zou, Yangmu Huang

“…Conclusion: BRICS-plus was still far from reaching the global 2030 targets for both disease areas. Adults aged ≥ 25 years have little progress in HIV new cases, and youth and adults in other STIs.…”
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Describing the Clinical and Laboratory Features and HLA-B Pattern of Adult-Onset Idiopathic Autoimmune Uveitis at a Tertiary Hospital in South India: A Cross-Sectional Study by Jyothi Visalakshy, Sandeep Surendran, Salil Ganu, Kannisha Shah, C. B. Mithun, Vishal Marwaha, Lalitha Biswas, Niveditha Kartha, Gopal Pillai

“…There is a scarcity of information available on clinical and laboratory features of adult-onset idiopathic autoimmune uveitis. Therefore, we conducted a single centre descriptive cross-sectional study. …”
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Pre-injury frailty and clinical care trajectory of older adults with trauma injuries: A retrospective cohort analysis of A large level I US trauma center. by Oluwaseun Adeyemi, Corita Grudzen, Charles DiMaggio, Ian Wittman, Ana Velez-Rosborough, Mauricio Arcila-Mesa, Allison Cuthel, Helen Poracky, Polina Meyman, Joshua Chodosh

“…<h4>Background</h4>Pre-injury frailty among older adults with trauma injuries is a predictor of increased morbidity and mortality.…”
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Behavioral intention to receive self-financed and fully-subsidized herpes zoster vaccines among community-living older adults in Hong Kong: A random telephone survey by Xue Liang, Erdi Gu, Doug H. Cheung, Danhua Ye, Fuk-Yuen Yu, Yuan Fang, Phoenix K.H. Mo, Zixin Wang

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Immunizing adult female mice with a TcpA-A2-CTB chimera provides a high level of protection for their pups in the infant mouse model of cholera. by Gregory A Price, Randall K Holmes

“…We developed a TcpA holotoxin-like chimera (TcpA-A2-CTB) to elicit both anti-TcpA and anti-CTB antibodies and evaluated its immunogenicity and protective efficacy in the infant mouse model of cholera. Adult female CD-1 mice were immunized intraperitoneally three times with the TcpA-A2-CTB chimera and compared with similar groups immunized with a TcpA+CTB mixture, TcpA alone, TcpA with Salmonella typhimurium flagellin subunit FliC as adjuvant, or CTB alone. …”
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Association between triglyceride-glucose (TyG) index and risk of depression in middle-aged and elderly Chinese adults: Evidence from a large national cohort study by Zhang-Yang Xu, Hong Zheng, Zi-Jun Pan, Shou-Yi Hu, Yun-Xia Wang, Wen-Jun Su

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Protective factors, risk factors, and intervention strategies in the prevention and reduction of crime among adolescents and young adults aged 12-24 years: A scoping review protocol. by Rosanna Mary Rooney, Amber Hopkins, Jacob Peckover, Kael Coleman, Rebecca Sampson, Rosa Alati, Sharinaz Hassan, Christina M Pollard, Jaya A R Dantas, Roanna Lobo, Zakia Jeemi, Sharyn Burns, Robert Cunningham, Stephen Monterosso, Lynne Millar, Sender Dovchin, Rhonda Oliver, Ranila Bhoyroo, Getinet Ayano

“…The aim of this scoping review is to identify and map the key risk and protective factors, along with intervention strategies, that are essential for recognizing adolescents and young adults at risk of crime.<h4>Methods</h4>This scoping review protocol has been developed in line with the Arksey and O'Malley framework and the Joanna Briggs Institute (JBI) Reviewers' Manual. …”
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Association of Asthma Control and Metered-Dose Inhaler Use Technique among Adult Asthmatic Patients Attending Outpatient Clinic, in Resource-Limited Country: A Prospective Study by Bezie Kebede, Girma Mamo, Abebaw Molla

“…A prospective observational study was conducted from March to August 22, 2018. All adult asthmatic patients who met the inclusion criteria were included in the study. …”
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Effect of Low-Intensity High-Repetition Versus High-Intensity Low-Repetition Elastic Band Resistance Training on Functional Physical Fitness and Myokine Levels in Older Adults by Moon Jin Lee, Jun-Young Sung, Jiyoun Kim

“…This study investigates the effects of low-intensity high-repetition (LI-HR) and high-intensity low-repetition (HI-LR) resistance training (RT) on functional fitness and myokines in older adults. A total of 30 participants (mean age ~76 years) were randomized into control (n = 10), LI-HR (n = 10), or HI-LR (n = 10) groups. …”
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Rare Manifestation of a Rare Disease, Acute Liver Failure in Adult Onset Still’s Disease: Dramatic Response to Methylprednisolone Pulse Therapy—A Case Report and Review by Nalini Valluru, Venkata S. Tammana, Michael Windham, Eyasu Mekonen, Rehana Begum, Andrew Sanderson

“…Adult onset Still’s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. …”
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Adapting a Mobile Health App for Smoking Cessation in Black Adults With Anxiety Through an Analysis of the Mobile Anxiety Sensitivity Program Proof-of-Concept Trial: Qualitative Study by Marshall K Cheney, Adam C Alexander, Lorra Garey, Matthew W Gallagher, Emily T Hébert, Anka A Vujanovic, Krista M Kezbers, Cameron T Matoska, Michael J Zvolensky, Michael S Businelle

“… BackgroundAt least half of smokers make a serious quit attempt each year, but Black adults who smoke are less likely than White adults who smoke to quit smoking successfully. …”
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Retrospective observational study of the association between changes in physical activity and frailty in middle-aged and older adults: evidence from the Korean Longitudinal Study of Aging (2006–2022) by Eun-Cheol Park, Ye Jun Jung, Junhyuk Kim, Yun Seo Jang

“…In the group that increased their physical activity, the OR was 0.57 (95% CI: 0.52 to 0.63), and higher ORs were observed for current smokers and those residing in rural areas.Conclusions This study demonstrated that persistent and increased physical activity is associated with lower frailty in middle-aged and older adults in Korea. Therefore, participation in physical activity in the older adults is one of the important ways to prevent frailty.…”
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Healthy food prescription incentive programme for adults with type 2 diabetes who are experiencing food insecurity: protocol for a randomised controlled trial, modelling and implementation studies by Colleen Norris, Tyler Williamson, Richard Oster, Dana Lee Olstad, Laura White, David J T Campbell, Sharlette Dunn, Kim D Raine, Mary L'Abbé, Richard Lewanczuk, Lorraine L Lipscombe, Eldon Spackman, Reed Beall, Kienan Williams, Sara Scott, Gabrielle L Zimmermann, Kerry A McBrien, Kieran J D Steer, Catherine B Chan, Sheila Tyminski, Seth Berkowitz, Alun L Edwards, Terry Saunders-Smith, Saania Tariq, Naomi Popeski, Sara Nejatinamini, Aruba Naser, Carlota Basualdo-Hammond, Petra O’Connell, Judy Seidel, Jason Cabaj

“…Introduction The high cost of many healthy foods poses a challenge to maintaining optimal blood glucose levels for adults with type 2 diabetes mellitus who are experiencing food insecurity, leading to diabetes complications and excess acute care usage and costs. …”
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Effects of the Vivifrail-B multicomponent exercise program based on society ecosystems theory on physical function in community-dwelling frail older adults: A randomized controlled trial by Yue Li, Shasha Li, Xu Weng, Xinyu Yang, Jianyi Bao, Shufang Liao, Yingxue Xi, Xiaofang Song, Guojing Guo

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