Age-related immune response disparities between adults and children with severe COVID-19: a case–control study in China by Hongliang Chen, Hongliang Chen, Yuan Li, Liping Yuan, Fen Liu, Qian Sun, Qian Sun, Qingkai Luo, Yefei Lei, Yinglan Hou, Jiayan Li, Liang Cai, Shixing Tang

“…BackgroundElucidation of immune response differences is critical for uncovering underlying mechanisms and developing potential intervention measures among adults and children with COVID-19.MethodsIn this retrospective study, we analyzed serum biochemical markers and cytokine profiles among adults and children with COVID-19 in the First People’s Hospital of Chenzhou in Hunan, China from 1 December 2022 to 13 February 2023. …”
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Glioma Image-Level and Slide-Level Gene Predictor (GLISP) for Molecular Diagnosis and Predicting Genetic Events of Adult Diffuse Glioma by Minh-Khang Le, Masataka Kawai, Kenta Masui, Takashi Komori, Takakazu Kawamata, Yoshihiro Muragaki, Tomohiro Inoue, Ippei Tahara, Kazunari Kasai, Tetsuo Kondo

“…In conclusion, GLISP is a two-stage AI framework for histology-based prediction of genetic events in adult gliomas, which is helpful in providing essential information for WHO 2021 molecular diagnoses.…”
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Coapplication of humic acid and gypsum affects soil chemical properties, rice yield, and phosphorus use efficiency in acidic paddy soils by Hartina, Tidarat Monkham, Patma Vityakon, Tanabhat-Sakorn Sukitprapanon

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Composite cardiovascular risk factor control in US adults with diabetes and relation to social determinants of health: The All of Us research program by Frances Golden, Johnathan Tran, Nathan D. Wong

“…This study aims to identify disparities in cardiovascular risk factor control based on most recent recommendations and relationships to social determinants of health in a large-scale real-world cohort of US adults. Methods: We analyzed data from 88,416 participants with T2DM in the NIH Precision Medicine Initiative All of Us Research Program 2018–2022. …”
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Mapping an evidence-based end-of-life care framework for older adults in Chinese nursing homes: protocol for a scoping review by Yuanyuan Zhao, Boon How Chew, Yuehua Tu, Eva Marie Gacasan

“…Introduction End-of-life care is essential for older adults aged ≥60, particularly those residing in long-term care facilities, such as nursing homes, which are known for their home-like environments compared with hospitals. …”
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Safety of Rimegepant in Adults with Migraine and Anxiety, Depression, or Using Antidepressants: Analysis of a Multicenter, Long-Term, Open-Label Study by David Kudrow, Susan Hutchinson, Glenn C. Pixton, Terence Fullerton

“…Conclusions Rimegepant showed favorable safety and tolerability in adults with migraine and a history of anxiety and/or depression and with SSRI and/or other antidepressant use. …”
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Metal mixtures exposure with risk of elevated serum neurofilament light chain concentrations in U.S. general adults, NHANES 2013–2014 by Yan Wang, Keyi Zhang, Hao Li, Si Liu, Linyao Ying, Lu Xiang, Na Liang, Liangkai Chen, Lin Xiao, Gang Luo

“…However, the relationship between metal mixtures exposure and serum neurofilament light chain (sNfL) concentrations, a valuable non-invasive biomarker of neurodegenerative diseases, in general adult populations remains understudied and unclear. …”
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Mortality among Alaska Native Adults with Confirmed Hepatitis C Virus Infection Compared with the General Population in Alaska, 1995–2016 by Sara S. Bressler, Dana Bruden, Leisha D. Nolen, Michael G. Bruce, Lisa Towshend-Bulson, Philip Spradling, Brian J. McMahon

“…This study compared demographic characteristics and age-adjusted death rates from 1995 to 2016 among Alaska Native (AN) adults infected with HCV (AK-HepC) to rates among the AN and non-AN adult populations living in Alaska. …”
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Effects of Electrical Stimulation on Activation of Mirror Neuron Network in Healthy Adults during Motor Execution and Imitation: An fNIRS Study by Yao Cui, Fang Cong, Fu-Biao Huang, Ming Zeng, Jun Wang

“…Results: A total of 102 healthy adults were recruited and 72 participants’ data were analysed in the final report. …”
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Giant Woolly Bear (larva), Giant or Great Leopard Moth (adult) Hypercompe scribonia (Stoll 1790) (Lepidoptera: Erebidae: Arctiinae) by Donald W. Hall

“…EENY599/IN1043: Giant Woolly Bear (larva), Giant or Great Leopard Moth (adult) Hypercompe scribonia (Stoll 1790) (Lepidoptera: Erebidae: Arctiinae) (ufl.edu) …”
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Waist Circumference, Body Mass Index, and Other Measures of Adiposity in Predicting Cardiovascular Disease Risk Factors among Peruvian Adults by K. M. Knowles, L. L. Paiva, S. E. Sanchez, L. Revilla, T. Lopez, M. B. Yasuda, N. D. Yanez, B. Gelaye, M. A. Williams

“…A total of 1,518 Peruvian adults were included in this study. Waist circumference (WC), body mass index (BMI), waist-hip ratio (WHR), waist-height ratio (WHtR), and visceral adiposity index (VAI) were examined. …”
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Effects of Different Nitrogen Fertilizer Application Rates on Soil Microbial Structure in Paddy Soil When Combined with Rice Straw Return by Xiannan Zeng, Qi Wang, Qiulai Song, Quanxi Liang, Yu Sun, Fuqiang Song

“…This experiment provides technical support for the application of the alternative fertilizer technology of straw return to the field and provides a theoretical basis for rational fertilization of paddy fields in a cold climate.…”
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Phase 1 study of safety, tolerability, and efficacy of intradermal DNA vaccine ASP2390 in adults allergic to house dust mites by Thomas Kayser, MD, BS, Ronald Smulders, MD, PhD, Tomohiro Kusawake, PhD, Erik Wambre, PhD, Gurunadh R. Chichili, PhD, Mary B. Blauwet, DrPH, Anna Spence, MS, Melanie Patton, BS, Rima Tabash, PhD, Hannah A. DeBerg, PhD, Sugandhika Khosa, MS, Philipp Badorrek, MD, Jens M. Hohlfeld, MD, Brian C. Ferslew, PharmD, PhD

“…Objective: We evaluated the safety, tolerability, and efficacy of first-in-human intradermal ASP2390 in adults with HDM allergy. Methods: A randomized, double-blind, placebo-controlled phase 1 trial was conducted in adults with HDM-induced allergic rhinitis. …”
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Oral Administration of the Endocannabinoid Anandamide during Lactation: Effects on Hypothalamic Cannabinoid Type 1 Receptor and Food Intake in Adult Mice by Carolina Aguirre, Valeska Castillo, Miguel Llanos

“…Western blots showed a 72% increase in CB1R abundance in AEA-treated 21-day-old mice, without differences in adult mice. Additionally, specific binding of 3[H]-CP55.940 to hypothalamic membranes from adult mice was significantly lower in those mice treated with AEA during lactation. …”
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Prevalence of cataract and its associated factors among adult diabetic patients attending at diabetic care clinics in Northwest Ethiopia, 2023 by Abebech Fikade Shumye, Melkamu Temeselew Tegegn, Matiyas Mamo Bekele

“…However, no studies have been conducted to assess the prevalence of cataract and associated factors among adult diabetic patients in the study area. Therefore, this study aimed to assess the prevalence of cataract and associated factors among adult diabetic patients in Northwest Ethiopia. …”
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Prevalence of non-contrast CT abnormalities in adults with reversible cerebral vasoconstriction syndrome: protocol for a systematic review and meta-analysis by Dean A Fergusson, Dar Dowlatshahi, Brian Dewar, Michel Shamy, Naomi Niznick, Risa Shorr, Ryan Daniel Gotesman

“…The aim of this systematic review and meta-analysis is to estimate the prevalence of NCCT abnormalities seen on neuroimaging of adult patients with RCVS.Methods and analysis We will search the Medline, Embase and the Cochrane Library databases for studies on the prevalence of NCCT abnormalities on neuroimaging of patients with RCVS. …”
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Clinical guidelines of the Russian gastroenterological association and the Russian society on studying of liver diseases on diagnostics and treatment of adult patients with hepatitis B by V. T. Ivashkin, N. D. Yushchuk, M. V. Mayevskaya, O. O. Znoyko, K. R. Dudina, G. N. Karetkina, E. A. Klimova, S. L. Maximov, Yu. V. Martynov, I. V. Mayev, Ch. S. Pavlov, Ye. A. Fedosyina, A. O. Bueverov, D. T. Abdurakhmanov, N. A. Malyshev, I. G. Nikitin, Ya. G. Moysyuk, T. L. Lapina, A. S. Trukhmanov, G. M. Kozhevnikova, K. V. Zhdanov, A. G. Rakhmanova, V. P. Chulanov, I. V. Shahgildyan, V. E. Syutkin, P. O. Bogomolov

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Serum Cystatin C and Coronavirus Disease 2019: A Potential Inflammatory Biomarker in Predicting Critical Illness and Mortality for Adult Patients by Dan Chen, Wenwu Sun, Jia Li, Bohua Wei, Wei Liu, Xiaopin Wang, Fan Song, Liangkai Chen, Junhui Yang, Li Yu

“…Serum cystatin C could be routinely monitored during hospitalization, which showed clinical importance in prognosticating for adult patients with COVID-19.…”
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Assessing type-2 diabetes risk based on the Indian diabetes risk score among adults aged 45 and above in India by Karthika Maniyara, Prakash Babu Kodali

“…Abstract Millions of Indian adults are pre-diabetic with a greater risk of developing type-2 diabetes mellitus (T2DM). …”
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Impact of alcoholic extract from sea cucumber (Holothuria parva) on letrozole–induced polycystic ovary syndrome in adult female rats by Samaneh Askari, Mohammad Reza Jafarzadeh Shirazi, Masoumeh Ahmadi, Arezoo Khoradmehr, Nadiar M. Mussin, Asset A. Kaliyev, Farzad Mohammad Rezazadeh, Mohammad Dadpasand Taromsari, Ali Bustani, Nader Tanideh, Kulyash R. Zhilisbayeva, Amin Tamadon

“…Objective: To explore the potential therapeutic impact of an alcoholic extract derived from the sea cucumber (Holothuria parva) on letrozole-induced polycystic ovary syndrome (PCOS) in adult female Sprague-Dawley rats. Methods: Sixteen female rats, aged 8 to 10 weeks, with a mean weight of (200±20) g, were randomly assigned to four groups: the control, PCOS, and two treatment groups receiving sea cucumber extract and metformin, respectively. …”
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