CAD-Q (COPD-Asthma Differentiation Questionnaire): Performance of a new diagnostic score to differentiate between COPD and asthma in adults by Alejandra Lozano-Forero, Eduardo Tuta-Quintero, Alirio R. Bastidas, Blanka Pacheco, Juan Cordero, Kamil Faizal, Miguel Molina, Irma Méndez, Andrés Cardona, Nicoll Navarro, Gabriela Bonilla, Manuela Franco, Juan Samboní, Julio de La Hoz, Georgina Doumat, David Portilla, Hannah Eljach

“…Results 235 (52.9%) patients had COPD and 209 (47.1%) had asthma. A score ≥ 20 on the CAD-Q questionnaire showed a ROC-curve of 70% (95% CI: 65–75; p < 0.001) with a sensitivity of 83.8% (95% CI: 81.1–86.6), specificity of 47.8% (95% CI: 44.1–51.6), positive predictive value of 37.8% (95% CI: 34.2–41.5), negative predictive value of 88.7% (95% CI: 86.3–91), LR + of 1.61 (95% CI: 1.447–1.786), LR − of 0.34 (95% CI: 0.304–0.376) for diagnosing COPD. …”
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Cx43 Inhibition Attenuates Sepsis-Induced Intestinal Injury via Downregulating ROS Transfer and the Activation of the JNK1/Sirt1/FoxO3a Signaling Pathway by Zhaowei Zou, Bin Liu, Lisi Zeng, Xianzi Yang, Renli Huang, Cheng Wu, Huijuan Zhu, Yi Gao, Dongdong Yuan, Jinlong Yu

“…Intestinal injury has long been considered to play a crucial role in the pathophysiology of sepsis and has even been characterized as the “motor” of it. …”
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