A blended learning approach for capacity strengthening to improve the quality of integrated HIV, TB, and malaria services during antenatal and postnatal care in LMICs: a feasibilit... by Alice Norah Ladur, Uzochukwu Egere, Marion Ravit, Florence Mgawadere, Christopher Murray, Sarah Ann White, Mohammed Hauwa, Rael Mutai, Lucy Nyaga, Shikuku Duncan, Issak Bashir, Olubunmi Olufunmilola Ayinde, Rukia Bakar, Leonard Katalambula, Carlo Federici, Aleksandra Torbica, Nicholas Furtado, Elizabeth Adjoa Kumah, Charles Ameh

“…Participants liked the BL approach due to its flexibility in learning, highly educative/relevant content, mixing of health worker cadres and CPD points. …”
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A Native LH1–RC–HiPIP Supercomplex from an Extremophilic Phototroph by Kazutoshi Tani, Ryo Kanno, Kenji V. P. Nagashima, Mai Kawakami, Naho Hiwatashi, Kazuna Nakata, Sakiko Nagashima, Kazuhito Inoue, Shinichi Takaichi, Endang R. Purba, Malgorzata Hall, Long-Jiang Yu, Michael T. Madigan, Akira Mizoguchi, Bruno M. Humbel, Yukihiro Kimura, Zheng-Yu Wang-Otomo

“…These distinct forms of LH1 indicate that the number of subunits in a Hlr. halophila LH1 complex is flexible and its size is a function of the photocomplex it encircles. …”
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System Design and Optimisation Study on a Novel CCHP System Integrated with a Hybrid Energy Storage System and an ORC by Jie Ji, Zujun Ding, Xin Xia, Yeqin Wang, Hui Huang, Chu Zhang, Tian Peng, Xiaolu Wang, Muhammad Shahzad Nazir, Yue Zhang, Baolian Liu, Xiaoying Jia, Ruisheng Li, Yaodong Wang

“…In this research, there is a hybrid energy storage unit enhancing the whole system’s operation flexibility while supplying cooling, heating, and power. …”
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Limnospira (Cyanobacteria) chemical fingerprint reveals local molecular adaptation by Théotime Roussel, Cédric Hubas, Sébastien Halary, Mathias Chynel, Charlotte Duval, Jean-Paul Cadoret, Tarik Meziane, Léa Vernès, Claude Yéprémian, Cécile Bernard, Benjamin Marie

“…Although the genes specifically involved in the production of these components remain unknown, we hypothesized that within extreme environments, such as those colonized by Limnospira, a large set of flexible genes could support the production of peculiar metabolite sets providing remarkable adaptations to specific local environmental conditions.IMPORTANCELimnospira are ubiquitous cyanobacteria with remarkable adaptive strategies allowing them to colonize and dominate a wide range of alkaline-saline environments worldwide. …”
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Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment by Annie S Anderson, Ronan E O’Carroll, Martine Stead, Robert J C Steele, Mary Wells, Maureen Macleod, Anna Campbell, Jacqui A Sugden, Jackie Rodger, Jennifer McKell

“…Physical activity data showed a positive trend towards increased activity overall, but no other changes in secondary outcomes were detected.Conclusions To make this intervention feasible for testing as a full trial, further research is required on (a) recruitment optimisation, (b) appropriate assessment tools, (c) protocols for phase 2 and 3, which can build in flexibility and (d) ways for NHS staff to facilitate the programme.Trial registration number ISRCTN52345929; Post-results.…”
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Deflection of screen surface and spatial deformation law of screen apertures during 1 mm elastic screening by Haishen JIANG, Ran YANG, Runyu LIU, Shijie YU, Peng GUO, Miao PAN, Long HUANG, Chenlong DUAN

“…To overcome the problems above, combining vibration testing and multi-flexible body dynamics simulation methods, the kinematic characteristics of elastic screen surface and 1 mm elastic screening test were carried out. …”
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Designing a Multimodal and Culturally Relevant Alzheimer Disease and Related Dementia Generative Artificial Intelligence Tool for Black American Informal Caregivers: Cognitive Walk... by Cristina Bosco, Ege Otenen, John Osorio Torres, Vivian Nguyen, Darshil Chheda, Xinran Peng, Nenette M Jessup, Anna K Himes, Bianca Cureton, Yvonne Lu, Carl V Hill, Hugh C Hendrie, Priscilla A Barnes, Patrick C Shih

“…ConclusionsOur study shows that, when designing for Black American older adults, a multimodal interaction with the generative AI system can allow individuals to choose their own interaction way and style based upon their interaction preferences and external constraints. This flexibility of interaction modes can guarantee an inclusive and engaging generative AI experience.…”
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Cutting-edge Bioinformatics strategies for synthesizing Cyclotriazadisulfonamide (CADA) analogs in next-Generation HIV therapies by Jay Gabriel B. Larga, Wrynan T. Munabirul, Abu Tayab Moin, Md Maisum Sarwar Jyoti, Mst Sanjida Nasrin, Minhaz Abdullah Al Mueid, Abdul Ahad, Anwar Parvez, Mst Sabrina Yeasmin, Rupali M. Barhate, Rajesh B. Patil, Margel C. Bonifacio

“…Molecular dynamics simulations using Gromacs-2020.4 revealed that JGL023 and JGL032 exhibited the most favorable binding to the Sec61 channel, as determined by evaluating ligand and residue flexibility, compactness, contact frequency, motion pathways, free energy, and other relevant parameters. …”
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UGT2B15 single nucleotide polymorphism reduces dabigatran acylglucuronide formation in humans by Jin-Woo Park, Jin-Woo Park, Jin-Woo Park, Jong-Min Kim, Young Yoon Bang, Kyoung-Ah Kim, Sungwook Yu, Ji-Young Park

“…BackgroundDabigatran etexilate (DABE), a prodrug of dabigatran (DAB), is a direct thrombin inhibitor used to prevent ischemic stroke and thromboembolism during atrial fibrillation. …”
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Patient centered medication treatment for opioid use disorder in rural Vermont: a qualitative study by Emily G. Hichborn, Owen B. Murray, Eilis I. Murphy, Tess E. Gallant, Sarah K. Moore, Bethany M. McLeman, John Saroyan, Anthony Folland, Megan Mitchell, Lisa A. Marsch

“…Individualizing care through flexible appointment scheduling was strongly valued, while inflexible scheduling fostered fear of not getting medication. …”
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Bayesian network for predicting mandibular third molar extraction difficulty by Tian Meng, Zhiyong Zhang, Xiao Zhang, Chao Zhang

“…Moreover, this Bayesian network model can flexibly improve inclusion factors and conditional probabilities with the development of relevant research and expert opinions, as well as change states and probabilities of relevant nodes based on actual clinical conditions. …”
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CitySEIRCast: an agent-based city digital twin for pandemic analysis and simulation by Shakir Bilal, Wajdi Zaatour, Yilian Alonso Otano, Arindam Saha, Ken Newcomb, Soo Kim, Jun Kim, Raveena Ginjala, Derek Groen, Edwin Michael

“…Our data pipelines and workflows are designed purposefully to be flexible and scalable so that we can implement the system on hybrid cloud/cluster systems and be agile enough to address different population settings and indeed, diseases. …”
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Exploring the impact and mechanisms of behavioral activation on sleep disorders in colorectal cancer: a randomized controlled trial by Anlong Li, Runze Huang, Han Ge, Dajie Liu, Shaochun Liu, Yingxue Jia, Jiaying Chai, Xinyi Zheng, Lijun Liu, Chen Gan, Jian Xu, Ling Cheng, Mingjun Zhang, Huaidong Cheng

“…Behavioral activation (BA), derived from cognitive behavioral therapy (CBT), offers a flexible, simple, and cost-effective alternative. BA highlights the importance of activation, a strategy that encourages active participation in positive, meaningful activities to boost positive experiences and reduce negative emotions, which may have potential benefits for individuals with sleep disorders. …”
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Virtual Integration of Satellite and In-situ Observation Networks (VISION) v1.0: In-Situ Observations Simulator (ISO_simulator) by M. R. Russo, M. R. Russo, S. L. Bartholomew, S. L. Bartholomew, D. Hassell, D. Hassell, A. M. Mason, E. Neininger, A. J. Perman, D. A. J. Sproson, D. Watson-Parris, D. Watson-Parris, N. L. Abraham, N. L. Abraham

“…Although this code was initially tested within the Unified Model (UM) framework, which is shared by the UK Earth System Model (UKESM), it was written as a flexible tool and it can be extended to work with other models.…”
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Effectiveness of Frequent Point-of-Care Molecular COVID-19 Surveillance in a Rural Workplace: Nonrandomized Controlled Clinical Trial Among Miners by Akshay Sood, William “Cotton” Jarrell, Xin W Shore, Nestor Sosa, Alisha Parada, Nicholas Edwardson, Alexandra V Yingling, Teah Amirkabirian, Qiuying Cheng, Ivy Hurwitz, Linda S Cook, Shuguang Leng, Orrin B Myers, Douglas J Perkins

“…ObjectiveThe objective of this study was to investigate the feasibility and effectiveness of using frequent point-of-care molecular workplace surveillance as an intervention strategy to prevent the spread of SARS-CoV-2 at essential rural workplaces (mining sites) where physical distancing, remote work, and flexible schedules are not possible. MethodsIn this nonrandomized controlled clinical trial conducted from February 2021, to March 2022, 169 miners in New Mexico (intervention cohort) and 61 miners in Wyoming (control cohort) were enrolled. …”
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LAS TRANSFORMACIONES TERRITORIALES FRONTERIZAS SEGÚN LA CONCEPCIÓN IDEOLOGICA DE FRONTERA (1991-1995) by Alicia Laurín

“…En Argentina se ha transitado desde una noción de frontera concebida como una divisoria rígida y cerrada hacia otra que la concibe como deseable y necesariamente flexible para el logro de la integración. Una y otra racionalidad determinaron un uso territorial fronterizo diferente por parte del Estado. …”
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Harnessing the Power of Machine Learning Guided Discovery of NLRP3 Inhibitors Towards the Effective Treatment of Rheumatoid Arthritis by Sidra Ilyas, Abdul Manan, Chanyoon Park, Hee-Geun Jo, Donghun Lee

“…MD simulations (200 ns) revealed strong structural stability, flexibility, and interactions in the selected complexes. …”
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Feasibility of fetal cardiac function and anatomy assessment by real-time spiral balanced steady-state free precession magnetic resonance imaging at 0.55T by Ye Tian, Jon Detterich, Jay D. Pruetz, Ecrin Yagiz, John C. Wood, Krishna S. Nayak

“…Real-time MRI allowed easy adjustment of scan plan, automatic whole-heart volumetric sweeping, and flexible choice of reconstruction temporal resolution. …”
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Study protocol of a randomised controlled trial on SISU, a software agent providing a brief self-help intervention for adults with low psychological well-being by Harald Baumeister, Ann-Marie Küchler, David Ebert, Natalie Bauereiss, Eileen Bendig, Benjamin Erb, Lena Weger, Echo Meißner

“…Secondary outcomes are emotional well-being (Flourishing Scale), psychological flexibility (Acceptance and Action Questionnaire-II), quality of life (Assessment of Quality of Life -8D), satisfaction with the intervention (Client Satisfaction Questionnaire-8) and side effects (Inventory for the assessment of negative effectsof psychotherapy). …”
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Investigating the Effects of Optimized Mineral Fertilization on Plant Growth, Physiological Traits, Tuber Yield, and Biochemical Contents of Potato Crop by Hadjer Chabani, Neji Tarchoun, Roua Amami, Wassim Saadaoui, Najla Mezghani, Alexios A. Alexopoulos, Spyridon A. Petropoulos

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