New epigenome players in the regulation of PCSK9-H3K4me3 and H3K9ac alterations by statin in hypercholesterolemia by Sushmitha Duddu, Yash T. Katakia, Rituparna Chakrabarti, Pooja Sharma, Praphulla Chandra Shukla

“…Together, these findings suggest that statin induces the colocalization of H3K4me3 and H3K9ac to transcribe PCSK9 actively and that inhibiting these marks reduces PCSK9 expression and ultimately increases hepatocyte LDL uptake. …”
Get full text

Active Cycle Of Breathing Technique Terhadap Fungsi Paru pada Pasien Paska Operasi Bedah Jantung by Fakrul Ardiansyah, Elly Nurachmah, Muhamad Adam

Get full text

La friche PCUK entre dépollution, renaturation et régénération paysagère by Elisa Baldin

“…Within this framework, the site known as Produits Chimiques Ugine Kuhlmann (PCUK), within the Lille metropolitan area, is studied as an unique testing ground for observing a succession of approaches adopted since 1984 in the rehabilitation of sites and polluted soils. …”
Get full text

Assessment of the Symmetry and Deformation of a Submarine Hull Using the PCSE Method by Dąbrowski Paweł, Marchel Łukasz, Kiciński Radosław, Lindenbergh Roderik

Subjects: Get full text

Changes induced in mouse lipid metabolism by simultaneous impact of antisense oligonucleotide derivatives to <i>apoB</i>, <i>PCSK9</i>, and <i>apoCIII</i> mRNAs by S. I. Oshevski, Y. I. Ragino, E. V. Kashtanova, Y. V. Polonskaya, E. M. Stakhneva, V. P. Nikolin, N. A. Popova, N. A. Kolchanov, M. I. Voevoda

“…The following combinations of ASOs were four times injected to the mouse caudal vein: 1) ASO to apoB, 2) ASO to apoCIII, 3) ASO to apoB and ASO to PCSK9, 4) ASO to apoB, ASO to PCSK9, and ASO to apoCIII, 5) ASO to apoB (three doses), ASO to PCSK9, and ASO to apoCIII (two doses), 6) ASO to PCSK9 and (ASO to apoCIII – only in the fourth administration). …”
Get full text

Design and Performance Analysis of MISO-SRMR-DCSK System over Rayleigh Fading Channels by Gang Zhang, Yi man Hao, Tian qi Zhang

“…This paper presents the design and performance analysis of a short reference multifold rate DCSK (SRMR-DCSK) system to overcome the major drawback. …”
Get full text

Targeting PCSK9, through an innovative cVLP-based vaccine, enhanced the therapeutic activity of a cVLP-HER2 vaccine in a preclinical model of HER2-positive mammary carcinoma by Laura Scalambra, Francesca Ruzzi, Olga Maria Pittino, Maria Sofia Semprini, Chiara Cappello, Stefania Angelicola, Arianna Palladini, Patrizia Nanni, Louise Goksøyr, Cyrielle Fougeroux, Manuel L. Penichet, Adam Frederik Sander, Pier-Luigi Lollini

Subjects: Get full text

Familial Hypercholesterolemia: Genetics, Symptoms, Diagnosis and Treatment - A Literature Overview by Maciej Rutkiewicz, Sabina Przygodzka, Katarzyna Gadżała, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

Subjects: Get full text

Causal relationship of familial hypercholesterolemia with risk of intestinal vascular disorders: A mendelian randomization study by Gang Wei, Cheng Zhang, Feng-Jie Shen, Hua-Qi Guo, Lin Liu

Subjects: Get full text

Efektivitas Pemberian Mobilisasi Dini terhadap Tonus Otot, Kekuatan Otot, dan Kemampuan Motorik Fungsional Pasien Hemiparise Paska Stroke Iskemik by Reni Prima Gusty Gusty

Get full text

Okvir C-MAG za borbenu pušku sa 100 metaka 5,56 x 45 mm, International Defense Review, 1990 by M.P.

Subjects: Get full text

Optical Mode Calculation in Large-Area Photonic Crystal Surface-Emitting Lasers by Mindaugas Radziunas, Eduard Kuhn, Hans Wenzel, Ben King, Paul Crump

Subjects: Get full text

Optimal calorie restriction threshold: effect of FATmax exercise combined with different proportions of calorie restriction on hypercholesterolemia by Yuetong Wu, Li Zhang, Jing Li, Boyang Xue, Wenyuan Shang, Yingli Lu

Subjects: “…proprotein convertase subtilisin kexin type 9 (PCSK9)…”
Get full text

Association of Insomnia, Lipid Profile, and Lipid-Lowering Medications: A Narrative Review by Fang Jia, Shun-Yi Shi, Si-Fan Fei, Min Zhou, Jian-Jun Li

Subjects: “…proprotein convertase subtilisin/kexin type 9 inhibitors (pcsk9i)…”
Get full text

Bir Kuşak Bir Yol Girişimi ve Türkiye: Türkiye Girişime Dâhil Olmalı mı? by Erdem ATEŞ

Subjects: Get full text

CHANGE OF DYNAMICS OF SALES AND IMPORT OF MOTOR VEHICLES IN THE RUSSIAN MARKET UNDER THE INFLUENCE OF INSTABILITY OF THE EXTERNAL ENVIRONMENT by A. Pasko

Get full text

ANTHROPOMETRIC MEASUREMENT BASED ON STRUCTURE FROM MOTION IMAGING TECHNIQUE by S. Paśko, M. Sutkowski

Get full text

FEATURES OF TRANSFORMATION OF TRADE STRUCTURE IN THE MODERN WORLD MOTOR VEHICLES’ MARKET by A. Pas’Ko

Get full text