Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice by Yihong Yang, Guanghua Xiong, Huangqi Shi, Yulin Peng, Jinghong Liu, Yaxuan Jiang, Min Lu, Hongbo Liu, Yong Liu

“…Ultimately, the use of 4-PBA to pharmacologically inhibit ER stress may substantially reduce liver damage caused by HIRI in mice.ConclusionTaken together, our results suggested that sinensetin could alleviate HIRI injury through suppressing GRP78/CHOP-mediated ER stress, which may provide a novel therapeutic strategy for treating liver ischemia-reperfusion injury in clinical practice.…”
Get full text

Phenylbutyric Acid Modulates Apoptosis and ER Stress‐Related Gene Expression in Glycogen Storage Disease Type Ib In Vitro Model by Marina Parezanovic, Nina Stevanovic, Marina Andjelkovic, Milena Ugrin, Sonja Pavlovic, Maja Stojiljkovic, Anita Skakic

“…Our results proved the concept that 4‐PBA could alleviate markers of ER stress detected in the GSD Ib in vitro model system and prevent cell death. …”
Get full text

Crystal structure of bis(5-amino-1,2,4-triazol-4-ium-3-yl)methane sulfate, C5H10N8O4S by Zhang Guo-Tao, Wang Hua, Li Hong-Ya, Yan Biao

Get full text

4-Phenylbutyric Acid Attenuates Pancreatic Beta-Cell Injury in Rats with Experimental Severe Acute Pancreatitis by Yu-pu Hong, Wen-yi Guo, Wei-xing Wang, Liang Zhao, Ming-wei Xiang, Fang-chao Mei, Ablikim Abliz, Peng Hu, Wen-hong Deng, Jia Yu

“…To investigate the effect of 4-phenylbutyric acid (4-PBA) on the beta-cell injury following SAP and the underlying mechanism, twenty-four Sprague-Dawley rats were randomly divided into sham-operation (SO) group, SAP model group, and 4-PBA treatment group. …”
Get full text

Response of Maize (Zea mays L.) to Different Rates of Palm Bunch Ash Application in the Semi-deciduous Forest Agro-ecological Zone of Ghana by S. Adjei-Nsiah

“…The highest maize grain yield of 4530 and 6120 kg ha-1 was obtained at PBA application rate of 2 tons ha-1 for the major and minor rainy seasons, respectively.…”
Get full text

Inhibition of Endoplasmic Reticulum Stress by 4-Phenyl Butyric Acid Presents Therapeutic Effects on Periodontitis: Experimental Studies In Vitro and in Rats by Yang Feng, Rong Zhang, Yi-rong Wang, Fei Chen, Qiang Luo, Chuan Cai, Yang Jiao, Peng Xue

“…Thus, our findings suggested ER stress might act as a promising therapeutic target against periodontitis.…”
Get full text

Mutant Prevention Concentrations of Imipenem and Meropenem against Pseudomonas aeruginosa and Acinetobacter baumannii by E. Dahdouh, S. H. Shoucair, S. E. Salem, Z. Daoud

“…Detection of the mechanisms of resistance was performed using Antibiotic Susceptibility Testing, Double Disk Synergy, disk antagonism, addition of NaCl to the medium, addition of PBA or EDTA to Carbapenem disks, addition of PBA to Cefoxitin disks, and CCCP test for 10 Pseudomonas spp. and Acinetobacter baumannii strains. …”
Get full text

Prussian Blue analogs and transition metal K-edge XMCD: a longstanding friendship by Bordage, Amélie, N’Diaye, Adama, Bleuzen, Anne

“…This short review presents the reciprocal investigation of PBA with TM K-edge XMCD, from the first studies demonstrating that qualitative local magnetic information could be obtained on PBA from TM K-edge XMCD until our on-going project aiming at fundamentally understanding TM K-edge XMCD thanks to PBAs as model-compounds.…”
Get full text

Endoplasmic Reticulum Stress Regulates Scleral Remodeling in a Guinea Pig Model of Form-Deprivation Myopia by Chengcheng Zhu, Qingzhong Chen, Ying Yuan, Min Li, Bilian Ke

“…In vitro, TM induced ER stress in scleral fibroblasts, which was suppressed by 4-PBA. The mRNA expression of TGF-β1 and COL1A1 was upregulated after TM stimulation for 24 hours, but downregulated for 48 hours. …”
Get full text

Synthesis of acrylonitrile functionalized hydroxymethylfurfural derivatives with Mg(OH)$_{{2}}$ under solvent-free conditions by Mancipe, Sonia, Coca, Valentina, Castillo, Juan-Carlos, Rojas, Hugo, Brijaldo, María Helena, Castañeda, Claudia, Martínez, José Jobanny, Romanelli, Gustavo Pablo

Get full text

The adaptation of rainbow trout to warmer water: Oxidative damage in the germinal line by Vianel Sevastei, Sonia A. Crichigno, M. Victoria Santos, Andrea Trochine, Julio C. Painefilú, Noemí Zaritzky, Víctor E. Cussac

Get full text

Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus by Haoyi Yang, Yuwen Zhang, Yuxin Hong, Yuan Wei, Yuning Zhu, Lei Huang, Yuanxun Yang, Runbin Sun, Runbin Sun, Runbin Sun, Juan Li, Juan Li, Juan Li

“…After comprehensive consideration, bile acids were taken as our target for accurate quantification via targeted metabolomics. …”
Get full text