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8821
Disulfidptosis-related gene signatures as prognostic biomarkers and predictors of immunotherapy response in HNSCC
Published 2025-01-01“…BackgroundDisulfidptosis is a newly discovered form of cell death associated with tumorigenesis, particularly under oxidative stress and metabolic disorder conditions. …”
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8822
Effects of deficit drip irrigation at different growth stages on citrus leaf physiology, fruit growth, yield, and water productivity in South China
Published 2025-02-01“…Meanwhile, the activities of superoxide dismutase, peroxidase, catalase and the content of proline also increased by 10.5 %-47.3 %, 24.9 %-77.4 %, 20.2–49.8 % and 10.1 %-39.0 %, respectively, which allowed crop to cope with DI-induced oxidative stress. When stomatal conductance (Gs) at stage I-IV reached 0.030–0.040, 0.074–0.096, 0.204–0.219, and 0.114–0.142 mmol·m−2·s−1, respectively, leaf net photosynthesis rate (Pn) did not significantly change, but transpiration rate was limited, and hereby enhanced instantaneous water use efficiency. …”
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8823
Ruthenium(II) Complex with 1-Hydroxy-9,10-Anthraquinone Inhibits Cell Cycle Progression at G0/G1 and Induces Apoptosis in Melanoma Cells
Published 2025-01-01“…Subsequent studies showed that (<b>1</b>) inhibits the proliferation of CHL-1 cells and induces apoptosis, associated at least in part with the pro-oxidant effect and cell cycle arrest at the G1/S transition.…”
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8824
Interactions of the emerging fungus Candida auris with Acanthamoeba castellanii reveal phenotypic changes with direct implications on the response to stress and virulence
Published 2025-02-01“…The MMC2 isolate displayed increased resistance to oxidative, osmotic, and thermal stresses upon interaction with A. castellanii, whereas MMC1 showed limited changes. …”
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8825
Coordination Chemistry of Mixed-Donor Pyridine-Containing Macrocyclic Ligands: From Optical to Redox Chemosensors for Heavy Metal Ions
Published 2024-12-01“…The maximum anodic shift of the ferrocene oxidation wave is observed in the presence of Pb<sup>2+</sup> (230 mV), to which corresponds a reaction coupling efficiency (RCE) value as large as 7.9 × 10<sup>3</sup>. …”
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8826
Toxic effects and mechanisms of nanoplastics and sulfonamide antibiotics on Scenedesmus obliquus
Published 2025-01-01“…The exposure of two NPs and four SAs and their binary mixtures differently promoted or inhibited superoxide dismutase and catalase activities in algal cells to different degrees and resulted in elevated levels of malondialdehyde content, suggesting that oxidative stress led to significant inhibition of chlorophyll content, total protein content, and growth of algal cells. …”
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8827
Astaxanthin mitigates doxorubicin-induced cardiotoxicity via inhibiting ferroptosis and autophagy: a study based on bioinformatic analysis and in vivo/vitro experiments
Published 2025-01-01“…The experimental results show that ASX significantly mitigates DOX-induced myocardial tissue damage, inflammatory response, oxidative stress, and damage to H9C2 cells. Mechanistically, ASX markedly ameliorates levels of ferroptosis and autophagy both in vitro and in vivo. …”
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8828
Brucea javanica oil inhibited the proliferation, migration, and invasion of oral squamous carcinoma by regulated the MTFR2 pathway
Published 2025-01-01“…At the same time, the expression of oxidative phosphorylation markers increased, the expression of glycolytic markers decreased, and glycolysis-mediated decomposition of reactive oxygen species decreased, and H2O2 and oxygen levels decreased.In addition, when MTFR2 expression increased or decreased, SOD2/H2O2 expression also increased or decreased.DiscussionIn this study, we concluded through in vitro and in vivo experiments that BJO may affect the SOD2/H2O2 signaling pathway by down-regulating MTFR2-mediated aerobic glycolysis, thereby inhibiting cell proliferation, Migration, and Invasion. …”
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8829
Metabolomics, network pharmacology, and microbiome analyses uncover the mechanisms of the Chinese herbal formula for the improvement of meat quality in spent hens
Published 2025-02-01“…Furthermore, the network pharmacology analysis indicated that CHF was closely associated with oxidative stress and lipid metabolism. The CHF supplementation increased the glutathione peroxidase level (P < 0.05) and upregulated gene expression related to the Nrf2 pathway (including HO-1, P < 0.05; Nrf2, P = 0.098; CAT, P = 0.060; GPX1, P = 0.063; and SOD2, P = 0.052) and lipid metabolism (including PPARγ, P < 0.05; SREBP1, P = 0.059; and CPT1A, P = 0.058). …”
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8830
Vaccarin suppresses diabetic nephropathy through <?A3B2 pi6?>inhibiting the EGFR/ERK1/2 signaling pathway
Published 2024-08-01“…RT-PCR is utilized to quantify the mRNA levels of renal fibrosis, oxidative stress and inflammation markers. The levels of malondialdehyde (MDA) and reactive oxygen species (ROS), as well as the content of glutathione peroxidase (GSH-Px), are measured. …”
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8831
Evaluation of the Residues of Rice (Oryza sativa L.), Black-Eyed Pea (Vigna unguiculata L.), Dill (Anethum graveolens L.), and Aubergine (Solanum melongena L.) on Characteristics o...
Published 2025-09-01“…To determine the organic carbon content in the soil before planting and during the mid-growth stage of the corn plant, organic carbon was oxidized using potassium dichromate in the presence of concentrated sulfuric acid, followed by titration with semi-normal ammonium ferrous sulfate in the presence of the ortho phenanthroline reagent (Walkley, 1934). …”
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8832
Artemisinin supplementation in concentrated cottonseed protein basal diets enhances growth, antioxidant capacity, intestinal immunity and microbiota in hybrid grouper (Epinephelus...
Published 2025-04-01“…Artemisinin supplementation significantly enhanced the activities of SOD, GSH-Px, CAT, and T-AOC in the liver and hindgut (P < 0.05),while also reducing MDA levels, thereby demonstrating its protective effect against oxidative stress and its ability to strengthen antioxidant defense system. …”
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8833
CHARACTERISTICS OF CYTOPROTECTIVE EFFECT ON THE GASTRIC MUCOSA OF CRYOPRESERVED PLACENTA EXTRACT UNDER WATER-IMMOBILIZATION STRESS
Published 2022-12-01“…The activity of NO synthases (NOS) in GM was determined spectrophotometrically by the amount of oxidized NADPH+H+. Results and Discussion. The use of CEP, as well as esomeprazole, led to a weakening of GM ulcers. …”
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8834
Pengaruh Pemberian Susu Coklat Terhadap Kadar F2Isoprostan pada Siswa di Pusat Pendidikan dan Latihan Olahraga Pelajar (PPLP) Sumatera Barat
Published 2015-09-01“…The increase in free<br />radicals if not neutralized by antioxidants in the body and it caused oxidative stress which can cause lipid peroxidation,<br />resulting in F2-isoprostane product compounds that can affect a variety of health problems. …”
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8835
Les vestiges fauniques de la rue Lecointre à Reims/Durocortorum : une carrière utilisée comme dépotoir
Published 2022-11-01“…The rare equine bones that present cut marks are likely related to an incidental recovery of raw materials (hides, tendons, muscle, bones). These deposits are clearly different from the collective management of equine corpses previously observed in Reims, and characterized by the mass disposal of carcasses in one place and resulting in an exclusive and impressive dumping site for these remains.…”
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8836
Mechanism of deactivation processes of excited iron(III) thiocyanato complexes with benacen-type ligands
Published 2006-01-01“…Formation of polystyrene containing bonded NCS group when irradiating the complexes in the presence of styrene monomer used as a radical scavenger indicates that the primary photoreduction of Fe(III) to Fe(II) is accompanied by the oxidation of NCS<mml:math alttext="$^ - $"> <mml:mrow> <mml:msup> <mml:mi/> <mml:mo>−</mml:mo> </mml:msup> </mml:mrow> </mml:math> ligand to <mml:math alttext="$^ ullet $"> <mml:mrow> <mml:msup> <mml:mi/> <mml:mo>•</mml:mo> </mml:msup> </mml:mrow> </mml:math>NCS radical. 4-R-benacen-ligands behave as an innocent moiety virtually not participating in the photoinduced redox processes. …”
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8837
Bone marrow mesenchymal stem cell-derived extracellular vesicles alleviate diabetes-exacerbated atherosclerosis via AMPK/mTOR pathway-mediated autophagy-related macrophage polariza...
Published 2025-01-01“…RAW264.7 macrophages were induced with oxidized low-density lipoprotein (ox-LDL) and high glucose (HG), co-cultured with BMSC-EVs, and analyzed for macrophage proliferation, migration, and foam cell formation. …”
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8838
Effects of olive leaf extract on exercise performance and muscle mitochondrial response in young healthy adults
Published 2025-01-01“…Targeted investigation of selected proteins involved in the oxidative phosphorylation pathway showed an overall decrease of expression immediately after exercise but did not reveal any differences between placebo and OLE. …”
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8839
Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro
Published 2025-02-01“…Enzyme-linked immunosorbent assays (ELISA) were used to assess the levels of pro-inflammatory cytokines, Fe2+, and associated oxidative stress indicators in the serum and cell supernatant. …”
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8840
Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia
Published 2025-01-01“…This study aims to explore the depression-like behavior, sleep changes, central oxidative stress response, pineal mitochondrial autophagy damage, melatonin secretion, histopathological changes of the pineal gland, and the expression of Pink1/Parkin signaling-related factors in CUMS+SD rats. …”
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