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8741
Association between exposure to perfluoroalkyl and polyfluoroalkyl substances with estimated glomerular filtration rate: Mediating role of serum albumin
Published 2025-01-01“…Functional enrichment analysis suggested PFAS impair renal function by affecting lipid metabolism and increasing oxidative stress. Conclusions: PFAS exposure is negatively associated with eGFR and positively associated with the risk of decreased renal function, with albumin playing a partial mediating role.…”
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8742
Machine learning-based plasma metabolomics for improved cirrhosis risk stratification
Published 2025-02-01“…Key metabolites, including branched-chain amino acids (BCAAs), lipids, and markers of oxidative stress, were identified as significant predictors. …”
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8743
Exploring the Anti-PANoptosis Mechanism of Dachaihu Decoction Against Sepsis-Induced Acute Lung Injury: Network Pharmacology, Bioinformatics, and Experimental Validation
Published 2025-01-01“…In vivo, DCHD improved lung histopathological injury, reduced inflammatory factor expression, and alleviated oxidative stress injury in lung tissues. In vitro, DCHD-DS alleviated cell morphology changes, the release of pro-inflammatory factors, and p65 nucleus aggregation. …”
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8744
Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats
Published 2019-01-01“…In heart, PPARα activation leads to overall lower levels of free FAs and specific changes in certain FAs, compared with control. Furthermore, β-oxidation in liver and the enzymatic activities of well-known PPARα targeted genes were higher following PPARα administration. …”
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8745
Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism
Published 2024-09-01“…Conclusions The research results unequivocally demonstrated that atorvastatin can modulate VPA-induced autism by suppressing inflammation, oxidative stress, and apoptosis through TLR4/NF-κB/NOX-2 signaling pathway. …”
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8746
Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis
Published 2025-01-01“…We provided evidence that the SIPS-like phenotype is more likely induced by TCC-mediated cytokine release rather than oxidative stress. Overall, targeting TCC formation could be a future approach to attenuate OA progression.…”
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8747
MT1G promotes iron autophagy and inhibits the function of gastric cancer cell lines by intervening in GPX4/SQSTM1
Published 2024-11-01“…Multiple studies have shown that Metallothionein-1G (MT1G) is closely associated with oxidative stress, ferroptosis, and autophagy. However, the role and potential mechanisms of MT1G in GC have not been fully elucidated. …”
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8748
Preliminary study on the coconut crab (Birgus latro) rearing in captive pond
Published 2009-01-01“…The rearing activity was done in captive pond sized 5x5x1.3 m3 divided into 22 smaller ponds sized 1x1x1.3 m3 with a hiding hole (constructed by pile stones), supported by two small ponds sized 30x40x40 cm3 for sea and fresh water stocks, respectively. …”
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8749
Influence of minor hydrocarbon seepage on sulfur cycling in marine subsurface sediments
Published 2025-02-01“…Metagenomic and metatranscriptomic data indicated metabolic potential and activity towards sulfate reduction and anaerobic oxidation of methane (AOM). Expression of functional marker genes (<i>aprAB</i>, <i>dsrAB</i>, <i>mcrA</i>) revealed metabolic activities by sulfate-reducing Desulfobacterota and methanotrophic ANME-1 archaea sustained by HC traces in the sediment. …”
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8750
Enrichment of electrotrophic microorganisms from contrasting shallow-sea hydrothermal environments in bioelectrochemical reactors
Published 2025-02-01“…IntroductionHydrothermal vents are inhabited by electrotrophic microorganisms, which are capable of oxidizing extracellular compounds, such as metals, to power their metabolisms. …”
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8751
Molecular Changes in Aqueous Humor Associated with Inflammation Following Cataract Surgery in Patients with Fuchs’ Endothelial Corneal Dystrophy
Published 2024-11-01“…Abstract Introduction To evaluate the anterior chamber (AC) inflammation in the early postoperative period after cataract surgery and before Descemet membrane endothelial keratoplasty (DMEK) by quantifying oxidative stress and inflammatory mediators in aqueous humor of patients with Fuchs’ endothelial corneal dystrophy (FECD). …”
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8752
Application of Near-infrared reflectance spectroscopy in the diagnosis of varicocele in children and adolescents
Published 2024-04-01“…Δ rSO2 >11% values indicated disturbances in spermogram related to oxidative stress (AUC=0.702, 95% DI (0.51-0.88), sensitivity – 82%, specificity – 61%, p=0.031). …”
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8753
Integrative application of licorice root extract and melatonin improves faba bean growth and production in Cd-contaminated saline soil
Published 2025-01-01“…Application of LRE + Mt significantly mitigated the Cd-induced oxidative damage by increasing the activity of reactive oxygen species (ROS) scavenging enzymes such as superoxide dismutase, catalase, ascorbate peroxidase, and glutathione reductase, in parallel with enhanced ascorbate and reducing glutathione content. …”
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8754
Effects of Lupeol on Intestinal Anastomosis After Experimental Intestinal Ischemia-Reperfusion Injury in Rats
Published 2025-01-01“…In this process, anastomotic strength is as important as inflammatory responses and oxidative stress. Therefore, we conducted the study to investigate the effects of lupeol on intestinal ischemia-reperfusion injury, not only biochemically and histopathologically but also on anastomotic strength and miRNAs.Methods: Female rats were randomly divided into six groups. …”
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8755
Application of the DEB-TKTD model with multi-omics data: Prediction of life history traits of Chinese mitten crab (Eriocheir sinensis) under different salinities
Published 2025-01-01“…The omics results indicated that at 18 ‰, the osmoregulatory capacity and oxidative stress resistance were enhanced, and vitellogenin synthesis was stimulated. …”
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8756
Impact of dietary lysophospholipids supplementation on growth performance, meat quality, and lipid metabolism in finishing bulls fed diets varying in fatty acid saturation
Published 2025-01-01“…Abstract Background The objective of this study was to evaluate the effects of dietary fatty acids (FA) saturation and lysophospholipids supplementation on growth, meat quality, oxidative stability, FA profiles, and lipid metabolism of finishing beef bulls. …”
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8757
Bioinformatics analysis of ferroptosis-related hub genes and immunoinfiltration in myocardial ischemia/reperfusion following heart transplantation
Published 2025-01-01“…Unlike other modes of cell death, ferroptosis depends on the accumulation of iron within the cell and the oxidative degradation of polyunsaturated fatty acids. …”
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8758
Analysis of mRNA Pentatricopeptide Repeat Domain 1 as a prospective oncogene in clear cell renal cell carcinoma that accelerates tumor cells proliferation and invasion via the Akt/...
Published 2025-01-01“…Abstract Background Although pentatricopeptide repeat domain 1 (PTCD1) has been found to modulate mitochondrial metabolic and oxidative phosphorylation, its contribution in the growth of clear cell renal cell carcinoma (ccRCC) remains unknown. …”
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8759
Trade-Off Between Enzymatic Antioxidant Defense and Accumulation of Organic Metabolite Affects Salt Tolerance of White Clover Associated with Redox, Water, and Metabolic Homeostase...
Published 2025-01-01“…However, Trp004 maintained significantly higher leaf relative water content and chlorophyll content as well as lower osmotic potential and oxidative damage, compared with KL under salt stress. …”
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8760
Exploring the potential benefits of areca nut extract in animal production: a review
Published 2025-02-01“…Its remarkable anti-inflammatory and antioxidant potential, along with its outstanding performance in antibacterial, antifungal, and antiviral activities, plays a crucial role in inhibiting various pathogens and protecting cells from oxidative damage. This review aims to comprehensively explore the biological activities of areca nut extract and delve into its practical application potential in enhancing animal production efficiency and promoting sustainable livestock development.The pervasive presence of antibiotic residues—including tetracyclines, sulfonamides, and quinolones—in agricultural products such as meat, milk, and eggs has raised significant concerns due to their extensive use in animal husbandry. …”
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