A machine learning model accurately identifies glycogen storage disease Ia patients based on plasma acylcarnitine profiles by Joost Groen, Bas M. de Haan, Ruben J. Overduin, Andrea B. Haijer-Schreuder, Terry GJ Derks, M. Rebecca Heiner-Fokkema

“…As GSD Ia patients demonstrate altered lipid metabolism and mitochondrial fatty acid oxidation, we built a machine learning model to identify GSD Ia patients based on plasma acylcarnitine profiles. …”
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Constraining the Geochemical Fingerprints of Gases from the UK Carboniferous Coal Measures at the Glasgow Geoenergy Observatories Field Site, Scotland by Rebecca M. Chambers, Gareth Johnson, Adrian J. Boyce, Stuart M. V. Gilfillan

“…Gas samples collected at depths of 63–79 m exhibit enrichments in 13CCH4 and 2H, indicating the oxidative consumption of CH4. This correlates with their proximity to the Glasgow Ell mine workings, which will have increased exposure to O2 from the atmosphere as a result of mining activities. …”
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The relationship between non-HDL-C/HDL-C ratio and bone mineral density: an NHANES study by Shuo Qi, Biao Peng, Zhanwang Xu, Daodi Qiu, Guoqing Tan

“…Further analysis suggests that dyslipidemia may influence bone metabolism through pathways such as inflammation and oxidative stress.ConclusionThe effect of NHHR on bone mineral density (BMD) varies by BMI, gender, and age. …”
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Genesis of the Daping Gold Deposit in the Middle Xuefeng Mountain Area, Southern China: Constraints from Geochemistry, Fluid Inclusion, and H-O-S Isotope by Xu Kong, Wen-Tian Mi, Xue-Yuan Qi, Shu-Jun Lǚ, Yu-Jun Dong, Jie Xin

“…Four stages of mineralization/alteration were identified: the first stage has mineral assemblages of quartz+pyrite+arsenopyrite±carbonate minerals, the second stage has mineral assemblages of quartz+polymetallic sulfide minerals (pyrite, arsenopyrite, chalcocite, galena, chalcopyrite, tetrahedrite)±chlorite±carbonate minerals, the third stage has mineral assemblages of quartz and carbonate minerals, and the supergene stage is characterized by limonite±patina which were formed by the oxidation of metal sulfides. Among them, the first stage and the second stage are the main gold mineralization stages. …”
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Exploring the Anti-depression Mechanism of Polygonatum ordoratum Based on GEO Database Combined with Network Pharmacology and Molecular Docking Technology by Zhenxu JIANG, Chaoxing WANG, Yuliang WANG, Hong ZHAO, Yu SHEN, Shiqing SUN, Yongzhe MA, Mingming SONG, Yu ZHANG

“…Conclusion: Yuzhu may exert its antidepressant effects through inflammatory response, oxidative stress, and prostaglandin synthesis pathways.…”
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Dexmedetomidine pretreatment enhances protective effect efficacy of pericytes agaist acute lung injury in septic mice by LUO Xi, ZHANG Zisen, YANG Ao

“…Conclusion　‍Dex pretreatment significantly enhances PCs’ protective effect on pulmonary vascular endothelial barrier functions in septic mice， which may be due to its enhancing anti-oxidative capacity of PCs. …”
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Metformin Ameliorates Ulcerative Colitis Through Inhibiting NLRP3 Inflammasome Activation by Cao R, Jing J, Ma Y, Qi W, Huang X, Zhang C, Lu Z, He J, Wang G, Ma Y, Zhang H

“…At last, Met exhibited an anti-oxidant effect, along with upregulating the level of UCP2 and NCF1.Conclusion: Met significantly ameliorated UC by inhibiting NLRP3 inflammasome activation in macrophages. …”
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Radiation-assisted tailoring of swelling behavior and water retention of Na-CMC/PAAm hydrogels for enhancing Beta Vulgaris under drought stress by Mahmoud A. El-diehy, Ibrahim I. Farghal, Mohamed A. Amin, Mohamed Mohamady Ghobashy, Abdelatti I. Nowwar, H. M. Gayed

“…Leaf chlorophyll content increased with a corresponding decline in stress enzymes indicating decreased oxidative damage. This eco-friendly Na-CMC/PAAm-based hydrogel seems to have potential use for addressing water scarcity and agricultural challenges.…”
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Conjugates of Phthalocyanines With Oligonucleotides as Reagents for Sensitized or Catalytic DNA Modification

“…Metallophthalocyanines were able to induce the DNA modification: phthalocyanines of Zn(II) and Al(III) were active as photosensitizers in the generation of singlet oxygen <mml:math alttext="$^{1}$chem{O_{2}}"> <mml:mrow> <mml:msup> <mml:mi/> <mml:mn>1</mml:mn> </mml:msup> <mml:msub> <mml:mtext>O</mml:mtext> <mml:mn>2</mml:mn> </mml:msub> </mml:mrow> </mml:math>, while phthalocyanine of Co(II) promoted DNA oxidation by molecular oxygen through the catalysis of formation of reactive oxygen species (<mml:math alttext="$^{cdot}$chem{{O_{2}}^{-}}"> <mml:msup> <mml:mi/> <mml:mo>&#x22C5;</mml:mo> </mml:msup> <mml:msubsup> <mml:mtext>O</mml:mtext> <mml:mn>2</mml:mn> <mml:mo>&#x2212;</mml:mo> </mml:msubsup> </mml:math>, <mml:math alttext="chem{H_{2}O_{2}}"> <mml:msub> <mml:mtext>O</mml:mtext> <mml:mn>2</mml:mn> </mml:msub> <mml:msub> <mml:mtext>H</mml:mtext> <mml:mn>2</mml:mn> </mml:msub> </mml:math>, OH). …”
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Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors by null Chunyan-Zou, null Yanpeng-He, null Changshun-Xie, null Fulai-Gao, null Xiaoli-Xie, null Xiukun-Chai, null Chenxi-He, null Dongqiang-Zhao

“…GO analysis results revealed that DEGs were involved in negative management of myocardial contraction, regulation of myocardial cell contraction, ethanol oxidation, cellular potassium ion homeostasis, and relaxation of cardiac muscle, and KEGG analysis showed that major DEGs were with cGMP-PKG signaling pathway. …”
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Hepatoprotective Effects of a Novel Trihoney against Nonalcoholic Fatty Liver Disease: A Comparative Study with Atorvastatin by Hamad Abdulsalam Hamad Alfarisi, Muhammad Bin Ibrahim, Zenab B. Hamad Mohamed, Nuraniza Azahari, Asmah Hanim Bt. Hamdan, Che Anuar Che Mohamad

“…Liver homogenate was analysed for oxidative stress parameters: superoxide dismutase (SOD), glutathione peroxidase (GPx), and malondialdehyde (MDA). …”
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Deciphering the Role of CD36 in Gestational Diabetes Mellitus: Linking Fatty Acid Metabolism and Inflammation in Disease Pathogenesis by Huang L, Zhang T, Zhu Y, Lai X, Tao H, Xing Y, Li Z

“…The modified expression and functionality of CD36 may contribute to inflammation and oxidative stress in maternal tissues, interfere with insulin signaling, and subsequently influence maternal insulin sensitivity and fetal growth, increasing the risk for GDM. …”
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Dose-Weighted Network Pharmacology: Evaluating Traditional Chinese Medicine Formulations for Lumbar Disc Herniation by Zhou C, Xiang T, Yu Y, Ma H, Liu C, Yang F, Yang L

“…GO and KEGG pathway analyses highlighted key pathways related to oxidative stress and inflammation, providing mechanistic insights into the effectiveness of the treatments.Conclusion: Incorporating dosage as a reference factor into network pharmacology research proved feasible and effective, emphasizing the importance of precise dosage control in TCM formulations for treating LDH. …”
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Effect of Dry Aging on Beef Muscle Proteins by Galina V. Gurinovich, Irina S. Patrakova, Vladislav A. Khrenov, Marina V. Patshina, Antonina I. Shevchenko

“…According to the amino acid analysis, the optimal result was most pronounced on day 42 as proven by the moderate oxidative changes in proteins.…”
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Ameliorative effect of curcuminoids in liver fibrosis rat model via regulating GIPC1 gene and modulating MMP-8/TIMP-3 balance mediated by miR-483-5p by Rana Mostafa Adel, Sara Mostafa Kamal, Eman Adel Sherif, Sara Hatem El-shafiey

“…Results The attained results revealed significant regressions in livers’ relative weights, serum ALT (alanine aminotransferase), AST (aspartate aminotransferase), ALP (alkaline phosphatase) and LDH (lactate dehydrogenase), plasma PDGF (platelet-derived growth factor), liver TOC (total oxidative capacity), TNF-α, IL-6, TGF-β1, and downregulation in GIPC1 gene expression, besides, significant elevation in liver TAC (total antioxidant capacity) in CURC-treated rats. …”
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A novel cryopreservation solution for adipose tissue based on metformin by Yaping Deng, Xin Liu, Xichao Jian, Yan Zhang, Yinchi Hou, Suyun Hou, Fang Qi, Shune Xiao, Chengliang Deng

“…Methods This study initially examined the effect of various concentrations of metformin (0, 1, 2, 4, and 8 mM) on oxidative damage in adipose tissue to identify the optimal concentration. …”
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miR-199a-5p Exacerbated Intestinal Barrier Dysfunction through Inhibiting Surfactant Protein D and Activating NF-κB Pathway in Sepsis by Xianjin Du, Dan Tian, Jie Wei, Chen Yan, Peng Hu, Xu Wu, Wenbin Yang, Zhanyong Zhu

“…Additionally, we observed that miR-199a-5p affected the oxidative damage and inflammation in the intestine tissues from sepsis mice. …”
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Phthalates toxicity in vivo to rats, mice, birds, and fish: A thematic scoping review by Mohammad Shah Alam, Zannatul Maowa, Mohammad Nazmol Hasan

“…Most studies related to testicular toxicity (37.60 %), hepatotoxicity (23.53 %), and ovarian toxicity (18.30 %) investigations, while the rest consisted of neurotoxicity (6.88 %), renal toxicity (6.53 %), and thyroid toxicity studies (4.57 %). Studies focused on oxidative stress (34.64 %), apoptosis (22.22 %), steroid hormone deprivation (20.26 %), lipid metabolism disorder (11.76 %), and immunotoxicity (5.88 %) as mechanisms of toxicity. …”
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Response mechanism of ethanol-tolerant Saccharomyces cerevisiae strain ES-42 to increased ethanol during continuous ethanol fermentation by Xue-Xue Ji, Quan Zhang, Bai-Xue Yang, Qing-Ran Song, Zhao-Yong Sun, Cai-Yun Xie, Yue-Qin Tang

“…At lower ethanol concentrations (nearly 70 g/L), genes involved in mitochondrial ribosomes, oxidative phosphorylation, the tricarboxylic acid (TCA) cycle, antioxidant enzymes, ergosterol synthesis, and glycerol biosynthesis were specifically upregulated compared to those at 60 g/L. …”
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ICAM1 blockade improves ischemic muscle reperfusion in diabetic mice by Ninon Foussard, Célia Bourguignon, Virginie Grouthier, Caroline Caradu, Candice Chapouly, Alain-Pierre Gadeau, Thierry Couffinhal, Marie-Ange Renault

“…Notably anti-ICAM1 therapy did diminish macrophage infiltration and oxidative stress but not myopathy suggesting that myopathy characterized by small myocytes expressing higher level of MYH2 could be responsible for microangiopathy. …”
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