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8501
Insight into the role of antioxidant in microbial lignin degradation: Ascorbic acid as a fortifier of lignin-degrading enzymes
Published 2025-02-01“…Proteomics analysis suggested that the enhancement in enzyme activity was more likely to attributed to the reinforcement of AA on oxidative protein folding and transportation, rather than changes in enzyme expression. …”
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8502
Effects of coenzyme Q10 on endothelial and cardiac function in patients undergoing haemodialysis: study protocol for a pilot randomised controlled trial
Published 2020-09-01“…Secondary outcomes are death or hospitalisation due to cardiovascular events, all-cause mortality, change of CoQ10 concentration, the ratio of ubiquinol to ubiquinone, the change of oxidative stress markers (including malondialdehyde and 8-hydroxy-deoxyguanosine) and Left Ventricular Mass Index.Ethics and dissemination Risks associated with CoQ10 are minor, even at doses as high as 1800 mg according to previous studies. …”
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8503
MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology
Published 2025-02-01“…They regulate processes, such as mitochondrial Ca2+ (mCa2+) uptake, mitochondrial adenosine triphosphate (ATP) production, calcium dynamics, oxidative stress (OS), and cell death. Regulation makes it a potential target for treating diseases, especially cardiovascular diseases, neurodegenerative diseases, inflammatory diseases, metabolic diseases, and tumors.…”
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8504
Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personal...
Published 2025-01-01“…Furthermore, the LMGC is integral to cellular processes related to oxidative stress and lipid metabolism, both of which are significant factors in the context of ferroptosis. …”
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8505
Phenolic and amino acid profiles, and antioxidant properties of third generation snack foods adding Citrus mitis by-products and milk powder: impact of extrusion processing and mic...
Published 2025-02-01“…Total flavonoid content (TFC), hydroxyl radical scavenging activity (HRSA), and inhibition of human LDL oxidation (ILDLox) decreased in PS2 regarding PS1. …”
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8506
Effect of Dietary Supplementation of <i>Durvillaea Antarctica</i> Meal on Production and Meat Quality Traits of Lambs
Published 2025-01-01“…However, changes were observed in meat quality traits, including increased redness and reduced luminosity in the loin for the high inclusion treatment, in addition to slight alterations in pH and lower lipid oxidation in lambs’ meat fed <i>Durvillaea antarctica</i>. …”
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8507
Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus
Published 2025-01-01“…Moreover, scRNA-seq revealed significantly decreased intestinal TCRγδ T cells (γδT) associated with reduced aryl-hydrocarbon receptor repressor (AHRR) expression and subsequent oxidative stress and ferroptosis in Lpr mice. Antioxidant selenium effectively reversed the loss of γδT in Lpr mice, improved the gut barrier, and alleviated lupus symptoms. …”
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8508
Antioxidant and Laxative Effects of Methanol Extracts of Green Pine Cones (<i>Pinus densiflora</i>) in Sprague-Dawley Rats with Loperamide-Induced Constipation
Published 2024-12-01“…Oxidative stress is the key cause of the etiopathogenesis of several diseases associated with constipation. …”
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8509
Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders
Published 2025-01-01“…Additionally, we showed that treatment with the senolytic cocktail corrected gene expression programs associated with fatty acid metabolism, oxidative phosphorylation, the P53 pathway, and DNA repair, which were all downregulated in obese mice. …”
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8510
Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p
Published 2019-01-01“…Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is one of the major receptors expressed on the endothelium of arterial wall with a key role in endothelial dysfunction and the development of atherosclerosis. …”
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8511
Soluble Receptor for Advanced Glycation End Products: A Protective Molecule against Intramyocardial Lipid Accumulation in Obese Zucker Rats?
Published 2019-01-01“…Genes promoting fatty acid transport, activation, and oxidation in mitochondria/peroxisomes were upregulated in OB hearts. …”
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8512
Neuroimaging stratification reveals the striatal vulnerability to stress as a risk for schizophrenia
Published 2025-01-01“…This mediation was associated with the genes enriched in both glutamatergic synapses and response to oxidative stress. The stratified association between the striatum and stress highlights the differential vulnerability to stress, contributing to the complexity of the gene-by-environment etiology of schizophrenia.…”
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8513
Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact
Published 2025-01-01“…This accumulation led to oxidative damage, inflammatory responses, and neurodegenerative changes in the optic tectum, resulting in cholinergic system dysfunction. …”
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8514
Gross soil N transformations and microbial communities in Luxembourg beech forest (Fagus sylvatica L.) soils along a pH gradient
Published 2025-02-01“…Autotrophic nitrification also increased with pH, corresponding to elevated ammonium supply from gross mineralization and higher abundances of ammonia-oxidizers. Heterotrophic nitrification was much lower than autotrophic nitrification in calcareous soils but equally important in acidic soils. …”
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8515
Duodenal Organoids From Metabolic Dysfunction-Associated Steatohepatitis Patients Exhibit Absorptive and Barrier Alterations
Published 2025-01-01“…MDEOs displayed altered digestive potential associated with reduced mature absorptive cell fate, but they retained their lipid metabolic capacity, possibly mediated by lipid oxidation in stem/progenitor cells. Additionally, MDEOs misexpressed components of tight and adherens junctions and desmosomes compared to controls. …”
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8516
Does hydrogen-rich water mitigate MP toxicity in rainbow trout (Oncorhyncus mykiss)? Monitoring with hematology, DNA damage, and apoptosis via ROS/GSH/MDA pathway
Published 2023-06-01“…In this direction, the following were determined: PP+PE chronic toxicity in aquatic organisms, the toxicity mechanism and the effect of HRW as a possible treatment method in blood tissue; with hematological indices ([RBC count [RBC], leukocyte count [WBC], hemoglobin value [Hb], hematocrit ratio [Hct], platelet count [PLT], hemoglobin count per erythrocyte [MCHC], mean hemoglobin amount per erythrocyte [MCH] and mean erythrocyte volume [MCV]) in other tissues (liver, gill and brain tissue) oxidative stress response (catalase [CAT]), glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), glutathione (GSH), reactive oxygen products (ROS), malondialdehyde ([MDA] levels), DNA damage (8-OHdG: 8-Hydroxy-2-Deoxyguanosine), and the apoptosis (caspase 3) levels were investigated. …”
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8517
Impact of Arbuscular Mycorrhizal Symbiosis on Photosynthetic, Antioxidant Enzyme, and Water Flux Parameters in Salt-Stressed Chickpea (<i>Cicer arietinum</i>) Plants
Published 2025-01-01“…AMF (arbuscular mycorrhizal fungus) reduces salt’s detrimental effects on plants’ growth by bolstering the plant’s antioxidant defense system, effectively reducing the damage caused by oxidative stress. In this study, the impact of AMF on salinity stress alleviation in chickpea was investigated in pot-grown experiments. …”
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8518
Toxicological effects of the environmental pollutant perfluoronanoic acid on the ground-dwelling arthropod Solenopsis invicta
Published 2025-01-01“…Elevated superoxide dismutase (SOD) and catalase (CAT) activities at higher PFNA concentrations indicated oxidative stress in RIFAs. Collectively, these findings demonstrate PFNA's concentration-dependent toxic and repellent effects on RIFAs, emphasizing the need for further research on PFNA toxicity in ground-dwelling arthropods and the potential of RIFAs as a bioassay species for pollutant assessment.…”
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8519
Characterization of meat quality, storage stability, flavor-related compounds, and their relationship in Korean Woorimatdag No. 2 chicken breast meat during cold storage
Published 2025-01-01“…In both groups, aerobic plate counts, volatile basic nitrogen, and lipid oxidation levels increased, whereas creatine and dipeptide levels gradually decreased during storage. …”
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8520
Molecular and Biochemical Mechanisms of Scutellum Color Variation in <i>Bactrocera dorsalis</i> Adults (Diptera: Tephritidae)
Published 2025-01-01“…Most genes associated with scutellum color variation were involved in three pathways: oxidative phosphorylation, porphyrin and chlorophyll metabolism, and terpenoid backbone biosynthesis. …”
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