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8481
Association of Serum Alpha-Tocopherol and Retinol with the Extent of Coronary Lesions in Coronary Artery Disease
Published 2018-01-01“…Increased alpha-tocopherol levels in patients with more extensive coronary artery lesions may have resulted from altered vitamin E metabolism with increased oxidative stress.…”
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8482
Comparison of Physicochemical Properties, Fatty Acid Composition and Mineral Contents in Common Carp (Cyprinus carpio L.) Fillet and the Native Traditional Product Carp Ham
Published 2016-12-01“…The traditional product, Carp Ham, preserved positive nutritional features, which were better highlighted by the fatty acid composition, health-related indices and oxidative stability. The study indicated that the traditional manufacturing method retains the most part of the nutritional constituents present in the carp fillets.…”
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8483
Transcriptomic and behavioral studies reveal that glutamate receptors are involved in depressive-like behavior in adult olive flounder Paralichthys olivaceus
Published 2025-01-01“…The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed that ribosome, oxidative phosphorylation and glutamatergic synapse pathway were over-represented. …”
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8484
Ozone exposure and cardiovascular disease: A narrative review of epidemiology evidence and underlying mechanisms
Published 2025-01-01“…Proposed biological mechanisms suggest that O3 exposure engenders respiratory and systemic inflammation, oxidative stress, disruption of autonomic nervous and neuroendocrine systems, as well as impairment of coagulation function, glucose, and lipid metabolism. …”
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8485
Thioredoxin‐interacting protein (TXNIP) is a substrate of the NEDD4‐like E3 ubiquitin‐protein ligase WWP1 in cellular redox state regulation of acute myeloid leukemia cells
Published 2025-01-01“…As a result, accumulation of TXNIP in response to WWP1 inactivation in AML blasts reduces Trx activity and increases ROS production, hence inducing cellular oxidative stress. Increased ROS generation in WWP1‐depleted cells culminates in DNA strand breaks and subsequent apoptosis. …”
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8486
A comprehensive analysis of the effect of quorum-sensing molecule 3-oxo-C12-homoserine lactone on Candida auris and Candida albicans
Published 2025-06-01“…Moreover, HSL reduced intracellular iron and zinc levels (p < 0.05-0.001); furthermore, it modulated C. auris metabolism toward beta-oxidation, which may be associated with the observed reduction in in vivo virulence at lower HSL concentrations compared with C. albicans. …”
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8487
Sleep Disorders and Reproductive Health: Mechanisms, Consequences, and Potential Interventions
Published 2025-02-01“…Chronic stress, obesity, and other factors accompanying sleep disturbances can impair the functioning of hormonal axes, ultimately leading to oxidative stress—a metabolic basis for fertility issues. …”
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8488
Heme Oxygenase-1 Reduces Sepsis-Induced Endoplasmic Reticulum Stress and Acute Lung Injury
Published 2018-01-01“…Furthermore, HO-1 activation by hemin reduced p-PERK, p-eIF2-α, ATF4, and CHOP protein expression and oxidative stress and lung cell apoptosis. Additionally, HO-1 antagonist could aggregate the ER stress-related ALI. …”
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8489
Molecular insight into reproductive toxicity and transgenerational effects of Cadmium exposure on Drosophila melanogaster
Published 2025-02-01“…Transcriptome analysis revealed that, Cd-induced oxidative stress and ion transport disruption in the F0 generation could underlie synaptic dysfunction and impaired follicle cell development, impacting reproductive behavior and oocyte fertility. …”
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8490
A Decades-Long Journey of Palmitoylethanolamide (PEA) for Chronic Neuropathic Pain Management: A Comprehensive Narrative Review
Published 2024-12-01“…Also, it tries to understand if it can modernize the field of therapy based on PEA, thus offering a better treatment option for individuals with chronic long-term inflammation, oxidative stress, and neuropathic or mixed pain with a neuropathic component. …”
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8491
Cathepsin-D and outcomes in peripartum cardiomyopathy: Results from IPAC
Published 2025-01-01“…Background: Cathepsin-D is a protease released during oxidative stress that cleaves prolactin (PRL) generating a 16 kDa fragment that is pro-apoptotic, anti-angiogenic, and has been implicated in the pathogenesis of peripartum cardiomyopathy (PPCM). …”
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8492
Inhibition of Mitochondrial Fission Reverses Simulated Microgravity-Induced Osteoblast Dysfunction by Enhancing Mechanotransduction and Epigenetic Modification
Published 2025-01-01“…These mitochondrial alterations are linked to elevated reactive oxygen species levels, a decrease in ΔΨm, and a metabolic shift from oxidative phosphorylation to glycolysis, resulting in decreased adenosine triphosphate production, which are all indicative of mitochondrial dysfunction. …”
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8493
Melatonin Enhances Maize Germination, Growth, and Salt Tolerance by Regulating Reactive Oxygen Species Accumulation and Antioxidant Systems
Published 2025-01-01“…Moreover, exogenous melatonin alleviated NaCl-induced membrane damage and oxidative stress, and reduced Na<sup>+</sup> content and excessively large quantities of reactive oxygen species (ROS). …”
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8494
Severe Obesity in Women Can Lead to Worse Memory Function and Iron Dyshomeostasis Compared to Lower Grade Obesity
Published 2023-01-01“…Thus, iron dyshomeostasis observed in severe obesity may aggravate the cognitive impairment by altering metabolic homeostasis and enhancing oxidative stress. These findings can contribute to searching for biomarkers that indicate cognitive performance in the population with obesity.…”
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8495
Phytochemical investigation and evaluation of antioxidant and antidiabetic activities in aqueous extracts of Cedrus atlantica
Published 2025-01-01“…Further research to isolate and identify the bioactive compounds in CA extract could lead to new therapeutic strategies for managing diabetes and oxidative stress-related conditions.…”
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8496
Acute Myocardial Infarction Reduces Respiration in Rat Cardiac Fibers, despite Adipose Tissue Mesenchymal Stromal Cell Transplant
Published 2020-01-01“…In conclusion, AMI led to mitochondrial dysfunction with oxidative phosphorylation disorders, and AD-MSC improved CS temporarily but was not able to avoid alterations in mitochondria function over time.…”
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8497
Transcriptome and DNA methylation analysis of the goat pineal gland during puberty
Published 2025-01-01“…Genes regulated by DNA methylation regulates genes primarily involved in metabolic processes, oxidative phosphorylation, and signaling pathways related to thermogenesis. …”
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8498
A new peptide inhibitor of C1QBP exhibits potent anti‐tumour activity against triple negative breast cancer by impairing mitochondrial function and suppressing homologous recombina...
Published 2025-01-01“…Its mechanism of action involves mitochondrial impairment and the inhibition of oxidative phosphorylation (OXPHOS), achieved through direct binding to C1QBP, thereby promoting its ubiquitin‐dependent degradation. …”
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8499
Serum uric acid level and subclinical left ventricular dysfunction: a community‐based cohort study
Published 2020-06-01“…Abstract Aims Although serum uric acid (SUA) level is correlated with oxidative stress and serves as a marker of poor prognosis in heart failure patients, its possible association with subclinical left ventricular (LV) dysfunction has not been evaluated. …”
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8500
The potential of urinary miR-200c-3p as a biomarker of fluorosis in rats
Published 2025-01-01“…Fluorine is a strong oxidizing element and excessive intake can have harmful effects, particularly on the body's calcified tissues. …”
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