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  1. 8301

    Single-nucleus RNA sequencing reveals distinct pathophysiological trophoblast signatures in spontaneous preterm birth subtypes by Cherilyn Uhm, Jianlei Gu, Weina Ju, Stephanie Pizzella, Hande Oktay, Joyce Yao-Chun Peng, Sararose Guariglia, Yong Liu, Hongyu Zhao, Yong Wang, Ramkumar Menon, Nanbert Zhong

    Published 2025-01-01
    “…In pPROM, heightened inflammation, oxidative stress, and vascular dysregulation with key pathways including tumor necrosis factor signaling, matrix metalloproteinase activation, and integrin-mediated cell adhesion, highlighted an invasive EVT profile potentially driven by hypoxic conditions and immune cell recruitment. …”
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  2. 8302

    A comprehensive analysis of the uterine microbiome in endometrial cancer patients - identification of Anaerococcus as a potential biomarker and carcinogenic cofactor by Olga Kuźmycz, Aleksandra Kowalczyk, Aleksandra Bolanowska, Anna Drozdzowska, Jakub Lach, Jakub Lach, Wiktoria Wierzbińska, Wiktoria Wierzbińska, Tomasz Kluz, Tomasz Kluz, Paweł Stączek

    Published 2025-01-01
    “…In vitro experiments were conducted to assess the functional impact of Anaerococcus on human uterine fibroblasts, including its ability to adhere to the human cells and induce oxidative stress.ResultsThe α-diversity metrics, including Shannon entropy and observed amplicon sequence variants (ASVs), revealed significantly higher microbial diversity in EC samples compared to EM. …”
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  3. 8303

    Protective Effect of Conditioned Medium of Immortalized Human Stem Cells from Exfoliated Deciduous Teeth Against Hair Graying Caused by X-Ray Irradiation via Its Antioxidative Acti... by Yasuhiro Katahira, Eri Horio, Natsuki Yamaguchi, Jukito Sonoda, Miu Yamagishi, Satomi Miyakawa, Fumihiro Murakami, Hideaki Hasegawa, Izuru Mizoguchi, Takayuki Yoshimoto

    Published 2025-01-01
    “…Hair graying is one of the common visible signs of human aging, resulting from decreased or abolished melanogenesis due to the depletion of melanocyte stem cells through excess accumulation of oxidative stress. Cell-free therapy using a conditioned medium (CM) of mesenchymal stem cells has been highlighted in the field of regenerative medicine owing to its potent therapeutic effects with lower regulatory hurdles and safety risk. …”
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  4. 8304

    Electronic and photophysical properties of copper (II) Complexes: Insights into solvatochromic Effects, Photoreduction, and fluorescence behavior by Haja Tar, Lama M. Alhomaidan, Lotfi Beji, Abrar S. Alnafisah, Noura Kouki, Sabri Messaoudi, Fahad M. Alminderej, Azizah A. Algreiby, Lotfi M. Aroua

    Published 2025-01-01
    “…While HL1 exhibits a single peak, HL2 displays two peaks, findings supported by calculated transition energies and oscillator strengths.Moreover, the oxidation processes of copper complexes with iodide salt and triethylamine unveil favorable electron transfer mechanisms, as corroborated by cyclic voltammograms and free energy change values. …”
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  5. 8305

    Autophagy-Enhancing Properties of <i>Hedyotis diffusa</i> Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient by Qiwen Zheng, Xiangji Jin, Trang Thi Minh Nguyen, Eun-Ji Yi, Se-Jig Park, Gyeong-Seon Yi, Su-Jin Yang, Tae-Hoo Yi

    Published 2025-01-01
    “…The decline in autophagy disrupts homeostasis in skin cells, leading to oxidative stress, energy deficiency, and inflammation—all key contributors to skin photoaging. …”
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  6. 8306

    Gas Seepage along the Edge of the Aquitaine Shelf (France): Origin and Local Fluxes by Livio Ruffine, Jean-Pierre Donval, Claire Croguennec, Laurent Bignon, Dominique Birot, Anne Battani, Germain Bayon, Jean-Claude Caprais, Nadine Lantéri, Denis Levaché, Stéphanie Dupré

    Published 2017-01-01
    “…It has been suggested that such a discrepancy was predominantly governed by the occurrence of anaerobic methane oxidation. The PEGAZ sampler also enabled us to estimate the local gas fluxes from the sampled streams. …”
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  7. 8307

    Short path molecular distillation of the essential oil from Pinus roxburghii oleoresin affords volatile fractions with powerful antioxidant and antimicrobial activities comparable... by Muhammad Adnan Ayub, Hawraz Ibrahim M. Amin, Rameen Waseem, Kamaran Younis M. Amin, Muhammad Asif Hanif, Amjad Hussain, Kovan Dilawar Issa, Jorge Ramírez, Chabaco Armijos, Muhammad Zubair, Giovanni Vidari

    Published 2025-02-01
    “…The antioxidant and antimicrobial activities varied between fractions and subfractions; however, their overall potency makes the P. roxburghii oleoresin a potential source of valuable natural antimicrobial products employable against various foodborne microbes and molds, as well as a source of preservative agents against food oxidation. Longifolene, 3-carene, α-pinene and β-pinene were identified by GC-MS analysis as the main constituents of the P. roxburghii turpentine essential oil and the most active fractions and sub-fractions. …”
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  8. 8308

    Branched-chain fatty acids from goat milk alleviate ulcerative colitis via the TLR4/NF-κB/NLRP3 pathway by Jiaxin Zhang, Jinjing Zhong, Zhengying Cui, Yu Shen, Yaping Zheng, Yu Zhang, Chaoxin Man, Yanmei Hou, Qianyu Zhao, Yujun Jiang

    Published 2024-11-01
    “…These results show that BCFAs extracted from goat milk can significantly alleviate weight loss in mice, and reduce the disease activity index and the activity of myeloperoxidase while increasing the content of antioxidant enzymes in colon tissue and reducing the oxidation stress response. These data also show that BCFAs can down-regulate the gene and protein expression of the toll-like receptor 4 (TLR4)/ nuclear factor κB p65 (NF-κB p65)/NOD-like receptor thermal protein domain associated protein 3 (NLRP3) signaling pathway, and at the same time significantly reduce the expression of pro-inflammatory factors tumor necrosis factor α (TNF-α), interleukin 1β (IL-1β), and IL-18 in colon tissue, and significantly increase the expression of the anti-inflammatory factor IL-10. …”
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  9. 8309

    Analysis of microstructural evolution and mechanical properties of FGH101 powder superalloy and IN718 deformed superalloy via inertia friction welding by Jun Zhou, Jun Zhou, Yongqiang Zhang, Yongqiang Zhang, Yongqiang Zhang, Feng Qin, Feng Qin, Xuelong Zhang, Xuelong Zhang, Hao Wang, Hao Wang, Ze Liu, Ze Liu, Wenhan Zhang, Wenhan Zhang, Caiyan Huang, Caiyan Huang, Chunbo Zhang, Chunbo Zhang

    Published 2025-01-01
    “…Nickel-based superalloys are indispensable in aerospace engines due to their exceptional high-temperature strength, oxidation resistance, and corrosion resistance, making them critical for joining processes such as inertia friction welding (IFW), which is favored for its efficiency and superior joint quality. …”
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  10. 8310

    Legionella pneumophila subverts the antioxidant defenses of its amoeba host Acanthamoeba castellanii by Alban Hay, Willy Aucher, Romain Pigeault, Joanne Bertaux, Alexandre Crépin, Quentin Blancart Remaury, Yann Héchard, Ascel Samba-Louaka, Romain Villéger

    Published 2025-01-01
    “…One such aspect is the role of oxidative stress, with studies focusing on reactive oxygen species (ROS) production by the host and putting less emphasis on the involvement of the host's antioxidant defenses during the infectious process. …”
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  11. 8311

    Visible light photocatalytic degradation of tetracycline using copper ferrite nanoparticles synthesized via Glycine-Assisted combustion method by A. Dinesh, K. Radhakrishnan, V. Renuga, Rajendra P. Patil, Suriyaprakash Rajadesingu, S. Suthakaran, L. Guganathan, Manikandan Ayyar, Madhappan Santhamoorthy, Lalitha Gnanasekaran, Munawar Iqbal

    Published 2025-01-01
    “…This study shows that green synthesized CuFe2O4 NPs are potentially useful as reusable visible-light photocatalysts for breaking down drugs, specifically tetracycline, through oxidation in water.…”
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  12. 8312

    Transformation of NO in Combustion Gases by DC Corona by Oleksandr Molchanov, Kamil Krpec, Jiří Horák, Lenka Kuboňová, František Hopan, Jiří Ryšavý, Marcelina Bury

    Published 2025-01-01
    “…The reactions involving O and OH radicals were more important in positive corona, whereas ozone-mediated oxidation dominated in negative corona. The research results demonstrate that ESP technology with DC corona offers a promising, energy-efficient solution for NO<sub>x</sub> control in small-scale combustion systems.…”
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  13. 8313

    A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression by Qiuyang Wang, Kai Feng, Guangsheng Wan, Wei Liao, Jing Jin, Peng Wang, Xiaolian Sun, Weijun Wang, Qing Jiang

    Published 2025-01-01
    “…Abstract RNA interference (RNAi) and oxidative stress inhibition therapeutic strategies have been extensively utilized in the treatment of osteoarthritis (OA), the most prevalent degenerative joint disease. …”
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  14. 8314

    Sorafenib-Loaded Silica-Containing Redox Nanoparticle Decreases Tumorigenic Potential of Lewis Lung Carcinoma by Babita Shashni, Hao Thi Tran, Long Binh Vong, Ren-Jei Chung, Yukio Nagasaki

    Published 2025-01-01
    “…Intestinal damage, a major adverse effect of free sorafenib, was significantly reduced with sora@siRNP, attributed to siRNP’s antioxidant property of mitigating oxidative damage. Survival rates in the experimental metastasis model were 66–74% for sorafenib but reached 100% for sora@siRNP, highlighting its superior efficacy and safety. …”
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  15. 8315

    Bushen Huoxue formula protects against renal fibrosis and pyroptosis in chronic kidney disease by inhibiting ROS/NLRP3-mediated inflammasome activation by Lin Liao, Pengyu Tao, Qiming Xu, Jie Chen, Weiwei Liu, Jing Hu, Jianrao Lu

    Published 2024-12-01
    “…Treatment with BSHX (0.25, 0.5, and 1 g/kg) significantly inhibited renal fibrosis and damage in 5/6 nephrectomized rats and simultaneously reduced oxidative stress and NLRP3 inflammasome activation. …”
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  16. 8316

    Regulation of Exogenous Strigolactone on Storage Substance Metabolism and Endogenous Hormone Levels in the Early Germination Stage of Rice Seeds Under Salt Stress by Jianqin Zhang, Dianfeng Zheng, Naijie Feng, Aaqil Khan, Rui Deng, Jian Xiong, Linchong Ding, Zhiyuan Sun, Jiahuan Li, Xiaohui Yang, Chen Wu

    Published 2024-12-01
    “…GR24 effectively enhanced the activities of superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX); increased ascorbic acid (ASA) and glutathione (GSH) levels; and reduced malondialdehyde (MDA) content. This reduced the oxidative damage of salt stress. Furthermore, GR24 significantly increased the contents of strigolactones (SLs), auxin (IAA), gibberellin (GA3), cytokinin (CTK) as well as IAA/ABA, CTK/ABA, GA/ABA, and SL/ABA ratios and reduced abscisic acid (ABA) levels. …”
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  17. 8317

    Metabolic conversion of phenol to polyhydroxyalkanoate (PHA) for addressing dual environmental challenges: A review by Izzati Sabri, Mohd Zulkhairi Mohd Yusoff, Nor Azlan Nor Muhammad, Li Sim Ho, Norhayati Ramli

    Published 2025-01-01
    “…Meanwhile, PHA can be synthesized through the acetoacetyl-CoA (pathway I), de novo fatty acids synthesis (pathway II), β-oxidation (pathway III), and the tricarboxylic acid (TCA) cycle, with the induction of these pathways are highly dependent on the substrate. …”
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  18. 8318

    Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model by Akinjide Moses Akinnuga, Angezwa Siboto, Bongiwe Khumalo, Ntethelelo Hopewell Sibiya, Phikelelani Ngubane, Andile Khathi

    Published 2020-01-01
    “…However, the administration of BA decreased liver enzyme concentrations, decreased hepatic oxidative stress, and improved antioxidant enzymes such as SOD and GPx. …”
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  19. 8319

    Isolation and characterization of mercuric reductase by newly isolated halophilic bacterium, Bacillus firmus MN8 by M. Noroozi, M.A. Amoozegar, A.A. Pourbabaei, N.S. Naghavi, Z. Nourmohammadi

    Published 2017-12-01
    “…To investigate enzyme activity of kinetic parameters, a spectrophotometer was used to measure the NADPH oxidation decrease at 340 n.m. The results showed that among the 21 halophilic and halotolerant strains isolated from Gavkhuni wetland, 4 were resistant to mercuric chloride. …”
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  20. 8320

    The Analysis of Estrogen-Degrading and Functional Metabolism Genes in Rhodococcus equi DSSKP-R-001 by Kejian Tian, Fanxing Meng, Qi Meng, Yan Gao, Lili Zhang, Le Wang, Yuqing Wang, Xue Li, Hongliang Huo

    Published 2020-01-01
    “…These DEGs included ABC transporters; estrogen-degrading genes, including those that perform initial oxidation and dehydrogenation reactions and those that further degrade the resulting substrates into small molecules; and metabolism genes that complete the intracellular transformation and utilization of estrogen metabolites through biological processes such as amino acid metabolism, lipid metabolism, carbohydrate metabolism, and the tricarboxylic acid cycle. …”
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