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8301
Single-nucleus RNA sequencing reveals distinct pathophysiological trophoblast signatures in spontaneous preterm birth subtypes
Published 2025-01-01“…In pPROM, heightened inflammation, oxidative stress, and vascular dysregulation with key pathways including tumor necrosis factor signaling, matrix metalloproteinase activation, and integrin-mediated cell adhesion, highlighted an invasive EVT profile potentially driven by hypoxic conditions and immune cell recruitment. …”
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8302
A comprehensive analysis of the uterine microbiome in endometrial cancer patients - identification of Anaerococcus as a potential biomarker and carcinogenic cofactor
Published 2025-01-01“…In vitro experiments were conducted to assess the functional impact of Anaerococcus on human uterine fibroblasts, including its ability to adhere to the human cells and induce oxidative stress.ResultsThe α-diversity metrics, including Shannon entropy and observed amplicon sequence variants (ASVs), revealed significantly higher microbial diversity in EC samples compared to EM. …”
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8303
Protective Effect of Conditioned Medium of Immortalized Human Stem Cells from Exfoliated Deciduous Teeth Against Hair Graying Caused by X-Ray Irradiation via Its Antioxidative Acti...
Published 2025-01-01“…Hair graying is one of the common visible signs of human aging, resulting from decreased or abolished melanogenesis due to the depletion of melanocyte stem cells through excess accumulation of oxidative stress. Cell-free therapy using a conditioned medium (CM) of mesenchymal stem cells has been highlighted in the field of regenerative medicine owing to its potent therapeutic effects with lower regulatory hurdles and safety risk. …”
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8304
Electronic and photophysical properties of copper (II) Complexes: Insights into solvatochromic Effects, Photoreduction, and fluorescence behavior
Published 2025-01-01“…While HL1 exhibits a single peak, HL2 displays two peaks, findings supported by calculated transition energies and oscillator strengths.Moreover, the oxidation processes of copper complexes with iodide salt and triethylamine unveil favorable electron transfer mechanisms, as corroborated by cyclic voltammograms and free energy change values. …”
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8305
Autophagy-Enhancing Properties of <i>Hedyotis diffusa</i> Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient
Published 2025-01-01“…The decline in autophagy disrupts homeostasis in skin cells, leading to oxidative stress, energy deficiency, and inflammation—all key contributors to skin photoaging. …”
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8306
Gas Seepage along the Edge of the Aquitaine Shelf (France): Origin and Local Fluxes
Published 2017-01-01“…It has been suggested that such a discrepancy was predominantly governed by the occurrence of anaerobic methane oxidation. The PEGAZ sampler also enabled us to estimate the local gas fluxes from the sampled streams. …”
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8307
Short path molecular distillation of the essential oil from Pinus roxburghii oleoresin affords volatile fractions with powerful antioxidant and antimicrobial activities comparable...
Published 2025-02-01“…The antioxidant and antimicrobial activities varied between fractions and subfractions; however, their overall potency makes the P. roxburghii oleoresin a potential source of valuable natural antimicrobial products employable against various foodborne microbes and molds, as well as a source of preservative agents against food oxidation. Longifolene, 3-carene, α-pinene and β-pinene were identified by GC-MS analysis as the main constituents of the P. roxburghii turpentine essential oil and the most active fractions and sub-fractions. …”
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8308
Branched-chain fatty acids from goat milk alleviate ulcerative colitis via the TLR4/NF-κB/NLRP3 pathway
Published 2024-11-01“…These results show that BCFAs extracted from goat milk can significantly alleviate weight loss in mice, and reduce the disease activity index and the activity of myeloperoxidase while increasing the content of antioxidant enzymes in colon tissue and reducing the oxidation stress response. These data also show that BCFAs can down-regulate the gene and protein expression of the toll-like receptor 4 (TLR4)/ nuclear factor κB p65 (NF-κB p65)/NOD-like receptor thermal protein domain associated protein 3 (NLRP3) signaling pathway, and at the same time significantly reduce the expression of pro-inflammatory factors tumor necrosis factor α (TNF-α), interleukin 1β (IL-1β), and IL-18 in colon tissue, and significantly increase the expression of the anti-inflammatory factor IL-10. …”
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8309
Analysis of microstructural evolution and mechanical properties of FGH101 powder superalloy and IN718 deformed superalloy via inertia friction welding
Published 2025-01-01“…Nickel-based superalloys are indispensable in aerospace engines due to their exceptional high-temperature strength, oxidation resistance, and corrosion resistance, making them critical for joining processes such as inertia friction welding (IFW), which is favored for its efficiency and superior joint quality. …”
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8310
Legionella pneumophila subverts the antioxidant defenses of its amoeba host Acanthamoeba castellanii
Published 2025-01-01“…One such aspect is the role of oxidative stress, with studies focusing on reactive oxygen species (ROS) production by the host and putting less emphasis on the involvement of the host's antioxidant defenses during the infectious process. …”
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8311
Visible light photocatalytic degradation of tetracycline using copper ferrite nanoparticles synthesized via Glycine-Assisted combustion method
Published 2025-01-01“…This study shows that green synthesized CuFe2O4 NPs are potentially useful as reusable visible-light photocatalysts for breaking down drugs, specifically tetracycline, through oxidation in water.…”
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8312
Transformation of NO in Combustion Gases by DC Corona
Published 2025-01-01“…The reactions involving O and OH radicals were more important in positive corona, whereas ozone-mediated oxidation dominated in negative corona. The research results demonstrate that ESP technology with DC corona offers a promising, energy-efficient solution for NO<sub>x</sub> control in small-scale combustion systems.…”
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8313
A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression
Published 2025-01-01“…Abstract RNA interference (RNAi) and oxidative stress inhibition therapeutic strategies have been extensively utilized in the treatment of osteoarthritis (OA), the most prevalent degenerative joint disease. …”
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8314
Sorafenib-Loaded Silica-Containing Redox Nanoparticle Decreases Tumorigenic Potential of Lewis Lung Carcinoma
Published 2025-01-01“…Intestinal damage, a major adverse effect of free sorafenib, was significantly reduced with sora@siRNP, attributed to siRNP’s antioxidant property of mitigating oxidative damage. Survival rates in the experimental metastasis model were 66–74% for sorafenib but reached 100% for sora@siRNP, highlighting its superior efficacy and safety. …”
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8315
Bushen Huoxue formula protects against renal fibrosis and pyroptosis in chronic kidney disease by inhibiting ROS/NLRP3-mediated inflammasome activation
Published 2024-12-01“…Treatment with BSHX (0.25, 0.5, and 1 g/kg) significantly inhibited renal fibrosis and damage in 5/6 nephrectomized rats and simultaneously reduced oxidative stress and NLRP3 inflammasome activation. …”
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8316
Regulation of Exogenous Strigolactone on Storage Substance Metabolism and Endogenous Hormone Levels in the Early Germination Stage of Rice Seeds Under Salt Stress
Published 2024-12-01“…GR24 effectively enhanced the activities of superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX); increased ascorbic acid (ASA) and glutathione (GSH) levels; and reduced malondialdehyde (MDA) content. This reduced the oxidative damage of salt stress. Furthermore, GR24 significantly increased the contents of strigolactones (SLs), auxin (IAA), gibberellin (GA3), cytokinin (CTK) as well as IAA/ABA, CTK/ABA, GA/ABA, and SL/ABA ratios and reduced abscisic acid (ABA) levels. …”
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8317
Metabolic conversion of phenol to polyhydroxyalkanoate (PHA) for addressing dual environmental challenges: A review
Published 2025-01-01“…Meanwhile, PHA can be synthesized through the acetoacetyl-CoA (pathway I), de novo fatty acids synthesis (pathway II), β-oxidation (pathway III), and the tricarboxylic acid (TCA) cycle, with the induction of these pathways are highly dependent on the substrate. …”
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8318
Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model
Published 2020-01-01“…However, the administration of BA decreased liver enzyme concentrations, decreased hepatic oxidative stress, and improved antioxidant enzymes such as SOD and GPx. …”
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8319
Isolation and characterization of mercuric reductase by newly isolated halophilic bacterium, Bacillus firmus MN8
Published 2017-12-01“…To investigate enzyme activity of kinetic parameters, a spectrophotometer was used to measure the NADPH oxidation decrease at 340 n.m. The results showed that among the 21 halophilic and halotolerant strains isolated from Gavkhuni wetland, 4 were resistant to mercuric chloride. …”
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8320
The Analysis of Estrogen-Degrading and Functional Metabolism Genes in Rhodococcus equi DSSKP-R-001
Published 2020-01-01“…These DEGs included ABC transporters; estrogen-degrading genes, including those that perform initial oxidation and dehydrogenation reactions and those that further degrade the resulting substrates into small molecules; and metabolism genes that complete the intracellular transformation and utilization of estrogen metabolites through biological processes such as amino acid metabolism, lipid metabolism, carbohydrate metabolism, and the tricarboxylic acid cycle. …”
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